Tony Ngo

TitlePostdoctoral Scholar
InstitutionUniversity of California San Diego
DepartmentSchool of Pharmacy and Pharmaceutical Science
Address9500 Gilman Drive #0747
La Jolla CA 92093
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    1. Coleman JLJ, Mouat MA, Wu J, Jancovski N, Bassi JK, Chan AY, Humphreys DT, Mrad N, Yu ZY, Ngo T, Iismaa S, Dos Remedios CG, Feneley MP, Allen AM, Graham RM, Smith NJ. Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control. Biol Sex Differ. 2018 Apr 06; 9(1):14. PMID: 29625592.
      View in: PubMed
    2. Naz S, Ngo T, Farooq U, Abagyan R. Analysis of drug binding pockets and repurposing opportunities for twelve essential enzymes of ESKAPE pathogens. PeerJ. 2017; 5:e3765. PMID: 28948099.
      View in: PubMed
    3. Coleman JL, Ngo T, Smith NJ. The G protein-coupled receptor N-terminus and receptor signalling: N-tering a new era. Cell Signal. 2017 05; 33:1-9. PMID: 28188824.
      View in: PubMed
    4. Ngo T, Ilatovskiy AV, Stewart AG, Coleman JL, McRobb FM, Riek RP, Graham RM, Abagyan R, Kufareva I, Smith NJ. Orphan receptor ligand discovery by pickpocketing pharmacological neighbors. Nat Chem Biol. 2017 02; 13(2):235-242. PMID: 27992882.
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    5. Coleman JL, Ngo T, Schmidt J, Mrad N, Liew CK, Jones NM, Graham RM, Smith NJ. Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity. Sci Signal. 2016 Apr 12; 9(423):ra36. PMID: 27072655.
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    6. Ngo T, Kufareva I, Coleman JLj, Graham RM, Abagyan R, Smith NJ. Identifying ligands at orphan GPCRs: current status using structure-based approaches. Br J Pharmacol. 2016 10; 173(20):2934-51. PMID: 26837045.
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    7. Coleman JL, Brennan K, Ngo T, Balaji P, Graham RM, Smith NJ. Rapid Knockout and Reporter Mouse Line Generation and Breeding Colony Establishment Using EUCOMM Conditional-Ready Embryonic Stem Cells: A Case Study. Front Endocrinol (Lausanne). 2015; 6:105. PMID: 26175717; PMCID: PMC4485191.
    8. Ngo T, Coleman JL, Smith NJ. Using constitutive activity to define appropriate high-throughput screening assays for orphan g protein-coupled receptors. Methods Mol Biol. 2015; 1272:91-106. PMID: 25563179.
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    9. Ngo T, Nicholas TJ, Chen J, Finch AM, Griffith R. 5-HT1A receptor pharmacophores to screen for off-target activity of a1-adrenoceptor antagonists. J Comput Aided Mol Des. 2013 Apr; 27(4):305-19. PMID: 23625023.
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