Tongbin Wu

TitleAssistant Project Scientist
InstitutionUniversity of California San Diego
Address9500 Gilman Drive #0613C
La Jolla CA 92093
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    1. Jiang L, Huang C, Gan Y, Wu T, Tang X, Wang Y, Wang R, Zhang Y. Radiation-induced late dysphagia after intensity-modulated radiotherapy in nasopharyngeal carcinoma patients: a dose-volume effect analysis. Sci Rep. 2018 Nov 06; 8(1):16396. PMID: 30401941.
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    2. Wang N, Li JY, Li S, Guo XC, Wu T, Wang WF, Li DS. Fibroblast growth factor 21 regulates foam cells formation and inflammatory response in Ox-LDL-induced THP-1 macrophages. Biomed Pharmacother. 2018 Oct 17; 108:1825-1834. PMID: 30372888.
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    3. Wang J, Wu T, Fang X, Min W, Yang Z. Characterization and immunomodulatory activity of an exopolysaccharide produced by Lactobacillus plantarum JLK0142 isolated from fermented dairy tofu. Int J Biol Macromol. 2018 Apr 21; 115:985-993. PMID: 29684452.
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    4. Lv C, Zeng HW, Wang JX, Yuan X, Zhang C, Fang T, Yang PM, Wu T, Zhou YD, Nagle DG, Zhang WD. The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG. Cell Death Dis. 2018 Feb 07; 9(2):165. PMID: 29416003.
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    5. Kim S, Jing K, Shin S, Jeong S, Han SH, Oh H, Yoo YS, Han J, Jeon YJ, Heo JY, Kweon GR, Park SK, Park JI, Wu T, Lim K. ?3-polyunsaturated fatty acids induce cell death through apoptosis and autophagy in glioblastoma cells: In vitro and in vivo. Oncol Rep. 2018 Jan; 39(1):239-246. PMID: 29192322.
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    6. Wu T, Mu Y, Bogomolovas J, Fang X, Veevers J, Nowak RB, Pappas CT, Gregorio CC, Evans SM, Fowler VM, Chen J. HSPB7 is indispensable for heart development by modulating actin filament assembly. Proc Natl Acad Sci U S A. 2017 Nov 07; 114(45):11956-11961. PMID: 29078393.
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    7. Lv J, Li D, Luo L, Wu T, Zhang S. Molecular transformation of natural and anthropogenic dissolved organic matter under photo-irradiation in the presence of nano TiO2. Water Res. 2017 11 15; 125:201-208. PMID: 28863342.
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    8. Fang X, Bogomolovas J, Wu T, Zhang W, Liu C, Veevers J, Stroud MJ, Zhang Z, Ma X, Mu Y, Lao DH, Dalton ND, Gu Y, Wang C, Wang M, Liang Y, Lange S, Ouyang K, Peterson KL, Evans SM, Chen J. Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy. J Clin Invest. 2017 Aug 01; 127(8):3189-3200. PMID: 28737513.
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    9. Chava S, Lee C, Aydin Y, Chandra PK, Dash A, Chedid M, Thung SN, Moroz K, Wu T, Nayak NC, Dash S. Chaperone-mediated autophagy compensates for impaired macroautophagy in the cirrhotic liver to promote hepatocellular carcinoma. Oncotarget. 2017 Jun 20; 8(25):40019-40036. PMID: 28402954.
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    10. Fang X, Stroud MJ, Ouyang K, Fang L, Zhang J, Dalton ND, Gu Y, Wu T, Peterson KL, Huang HD, Chen J, Wang N. Adipocyte-specific loss of PPAR? attenuates cardiac hypertrophy. JCI Insight. 2016 Oct 06; 1(16):e89908. PMID: 27734035.
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    11. Qadir XV, Chen W, Han C, Song K, Zhang J, Wu T. miR-223 Deficiency Protects against Fas-Induced Hepatocyte Apoptosis and Liver Injury through Targeting Insulin-Like Growth Factor 1 Receptor. Am J Pathol. 2015 Dec; 185(12):3141-51. PMID: 26598234; PMCID: PMC4729243 [Available on 12/01/16].
    12. Tong G, Liu Y, Wu T, Ye Y, Tong C. High-quality elliptical iron glycolate nanosheets: selective synthesis and chemical conversion into FexOy nanorings, porous nanosheets, and nanochains with enhanced visible-light photocatalytic activity. Nanoscale. 2015 Oct 21; 7(39):16493-503. PMID: 26394606.
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    13. Shimoda Y, Matsuo K, Kitamura Y, Ono K, Ueyama T, Matoba S, Yamada H, Wu T, Chen J, Emoto N, Ikeda K. Diabetes-Related Ankyrin Repeat Protein (DARP/Ankrd23) Modifies Glucose Homeostasis by Modulating AMPK Activity in Skeletal Muscle. PLoS One. 2015; 10(9):e0138624. PMID: 26398569; PMCID: PMC4580461.
    14. Chen W, Han C, Zhang J, Song K, Wang Y, Wu T. miR-150 Deficiency Protects against FAS-Induced Acute Liver Injury in Mice through Regulation of AKT. PLoS One. 2015; 10(7):e0132734. PMID: 26196694; PMCID: PMC4510058.
    15. Chen W, Han C, Zhang J, Song K, Wang Y, Wu T. Deletion of Mir155 prevents Fas-induced liver injury through up-regulation of Mcl-1. Am J Pathol. 2015 Apr; 185(4):1033-44. PMID: 25794705; PMCID: PMC4380848.
    16. Wu T, Fu XD. Genomic functions of U2AF in constitutive and regulated splicing. RNA Biol. 2015; 12(5):479-85. PMID: 25901584; PMCID: PMC4615725.
    17. Shao C, Yang B, Wu T, Huang J, Tang P, Zhou Y, Zhou J, Qiu J, Jiang L, Li H, Chen G, Sun H, Zhang Y, Denise A, Zhang DE, Fu XD. Mechanisms for U2AF to define 3' splice sites and regulate alternative splicing in the human genome. Nat Struct Mol Biol. 2014 Nov; 21(11):997-1005. PMID: 25326705; PMCID: PMC4429597.
    18. Huang J, Wu T, Guo Z, Lou T, Yu S, Gong W, Ji C. Crystallization and preliminary X-ray diffraction analysis of D53H mutant Escherichia coli cAMP receptor protein. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Dec; 69(Pt 12):1436-9. PMID: 24316848; PMCID: PMC3855738.
    19. Domenighetti AA, Chu PH, Wu T, Sheikh F, Gokhin DS, Guo LT, Cui Z, Peter AK, Christodoulou DC, Parfenov MG, Gorham JM, Li DY, Banerjee I, Lai X, Witzmann FA, Seidman CE, Seidman JG, Gomes AV, Shelton GD, Lieber RL, Chen J. Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice. Hum Mol Genet. 2014 Jan 01; 23(1):209-25. PMID: 23975679; PMCID: PMC3916749.
    20. Lu D, Han C, Wu T. 15-hydroxyprostaglandin dehydrogenase-derived 15-keto-prostaglandin E2 inhibits cholangiocarcinoma cell growth through interaction with peroxisome proliferator-activated receptor-?, SMAD2/3, and TAP63 proteins. J Biol Chem. 2013 Jul 05; 288(27):19484-502. PMID: 23687300; PMCID: PMC3707651.
    21. He J, Kang L, Wu T, Zhang J, Wang H, Gao H, Zhang Y, Huang B, Liu W, Kou Z, Zhang H, Gao S. An elaborate regulation of Mammalian target of rapamycin activity is required for somatic cell reprogramming induced by defined transcription factors. Stem Cells Dev. 2012 Sep 20; 21(14):2630-41. PMID: 22471963.
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    22. Qiu R, Wang F, Liu M, Yang Z, Wu T, Ji C. Crystallization and preliminary X-ray analysis of the yeast tRNA-thiouridine modification protein 1 (Tum1p). Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Aug 01; 67(Pt 8):953-5. PMID: 21821903; PMCID: PMC3151136.
    23. Wu T, Jia L, Du R, Tao X, Chen J, Cheng B. Genome-wide analysis reveals the active roles of keratinocytes in oral mucosal adaptive immune response. Exp Biol Med (Maywood). 2011 Jul; 236(7):832-43. PMID: 21676921.
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    24. Xue Y, Zhou Y, Wu T, Zhu T, Ji X, Kwon YS, Zhang C, Yeo G, Black DL, Sun H, Fu XD, Zhang Y. Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. Mol Cell. 2009 Dec 25; 36(6):996-1006. PMID: 20064465; PMCID: PMC2807993.
    25. Li G, Han C, Xu L, Lim K, Isse K, Wu T. Cyclooxygenase-2 prevents fas-induced liver injury through up-regulation of epidermal growth factor receptor. Hepatology. 2009 Sep; 50(3):834-43. PMID: 19585617; PMCID: PMC2758493.
    26. Yin G, Ji C, Zeng L, Wang Z, Wang J, Shen Z, Wu T, Gu S, Xie Y, Mao Y. Cloning and characterization of a novel KRAB-domain-containing zinc finger gene (ZNF284L). Mol Biol Rep. 2006 Jun; 33(2):137-44. PMID: 16817023.
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    27. Yin G, Ji C, Wu T, Shen Z, Xu X, Xie Y, Mao Y. Cloning, characterization and subcellular localization of a gene encoding a human Ubiquitin-conjugating enzyme (E2) homologous to the Arabidopsis thaliana UBC-16 gene product. Front Biosci. 2006 May 01; 11:1500-7. PMID: 16368532.
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    28. Lu DP, Dong L, Wu T, Huang XJ, Zhang MJ, Han W, Chen H, Liu DH, Gao ZY, Chen YH, Xu LP, Zhang YC, Ren HY, Li D, Liu KY. Conditioning including antithymocyte globulin followed by unmanipulated HLA-mismatched/haploidentical blood and marrow transplantation can achieve comparable outcomes with HLA-identical sibling transplantation. Blood. 2006 Apr 15; 107(8):3065-73. PMID: 16380454.
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