Thomas Broggini

TitlePostdoctoral Scholar
InstitutionUniversity of California San Diego
Address9500 Gilman Drive #0374
La Jolla CA 92093
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    1. Uhl C, Markel M, Broggini T, Nieminen M, Kremenetskaia I, Vajkoczy P, Czabanka M. EphB4 mediates resistance to antiangiogenic therapy in experimental glioma. Angiogenesis. 2018 Jul 10. PMID: 29987450.
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    2. Acker G, Piper SK, Datwyler AL, Broggini T, Kremenetskaia I, Nieminen-Kelhä M, Lips J, Harms U, Mueller S, Lättig-Tünnemann G, Trachsel E, Palumbo A, Neri D, Klohs J, Endres M, Vajkoczy P, Harms C, Czabanka M. Targeting the extradomain A of fibronectin allows identification of vascular resistance to antiangiogenic therapy in experimental glioma. Oncotarget. 2018 Jun 12; 9(45):27760-27772. PMID: 29963235.
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    3. Bayerl SH, Nieminen-Kelhä M, Broggini T, Vajkoczy P, Prinz V. Lateral Chronic Cranial Window Preparation Enables In Vivo Observation Following Distal Middle Cerebral Artery Occlusion in Mice. J Vis Exp. 2016 12 29; (118). PMID: 28060307.
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    4. Broggini T, Schnell L, Ghoochani A, Mateos JM, Buchfelder M, Wiendieck K, Schäfer MK, Eyupoglu IY, Savaskan NE. Plasticity Related Gene 3 (PRG3) overcomes myelin-associated growth inhibition and promotes functional recovery after spinal cord injury. Aging (Albany NY). 2016 Oct 15; 8(10):2463-2487. PMID: 27744421.
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    5. Broggini T, Piffko A, Hoffmann CJ, Harms C, Vajkoczy P, Czabanka M. Passive Entrapment of Tumor Cells Determines Metastatic Dissemination to Spinal Bone and Other Osseous Tissues. PLoS One. 2016; 11(9):e0162540. PMID: 27603673; PMCID: PMC5014376.
    6. Fan Z, Bittermann-Rummel P, Yakubov E, Chen D, Broggini T, Sehm T, Hatipoglu Majernik G, Hock SW, Schwarz M, Engelhorn T, Doerfler A, Buchfelder M, Eyupoglu IY, Savaskan NE. PRG3 induces Ras-dependent oncogenic cooperation in gliomas. Oncotarget. 2016 May 03; 7(18):26692-708. PMID: 27058420.
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    7. Broggini T, Wüstner M, Harms C, Stange L, Blaes J, Thomé C, Harms U, Mueller S, Weiler M, Wick W, Vajkoczy P, Czabanka M. NDRG1 overexpressing gliomas are characterized by reduced tumor vascularization and resistance to antiangiogenic treatment. Cancer Lett. 2016 10 01; 380(2):568-76. PMID: 26297987.
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    8. Broggini T, Czabanka M, Piffko A, Harms C, Hoffmann C, Mrowka R, Wenke F, Deutsch U, Grötzinger C, Vajkoczy P. ICAM1 depletion reduces spinal metastasis formation in vivo and improves neurological outcome. Eur Spine J. 2015 Oct; 24(10):2173-81. PMID: 25711910.
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    9. Savaskan NE, Fan Z, Broggini T, Buchfelder M, Eyüpoglu IY. Neurodegeneration and the Brain Tumor Microenvironment. [corrected]. Curr Neuropharmacol. 2015; 13(2):258-65. PMID: 26411769; PMCID: PMC4598438.
    10. Czabanka M, Bruenner J, Parmaksiz G, Broggini T, Topalovic M, Bayerl SH, Auf G, Kremenetskaia I, Nieminen M, Jabouille A, Mueller S, Harms U, Harms C, Koch A, Heppner FL, Vajkoczy P. Combined temozolomide and sunitinib treatment leads to better tumour control but increased vascular resistance in O6-methylguanine methyltransferase-methylated gliomas. Eur J Cancer. 2013 Jun; 49(9):2243-52. PMID: 23499430.
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    11. Broggini T, Nitsch R, Savaskan NE. Plasticity-related gene 5 (PRG5) induces filopodia and neurite growth and impedes lysophosphatidic acid- and nogo-A-mediated axonal retraction. Mol Biol Cell. 2010 Feb 15; 21(4):521-37. PMID: 20032306; PMCID: PMC2820418.
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