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Tanya Nguyen

Title(s)Assistant Clinical Professor, Psychiatry
SchoolHealth Sciences
Phone619-471-3925
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    Dr. Tanya Nguyen earned her undergraduate degree in Neuroscience from the University of Southern California and her Ph.D. in Clinical Psychology (with an emphasis in Neuropsychology) from the SDSU/UCSD Joint Doctoral Program in Clinical Psychology. She completed her clinical internship at the VA Palo Alto and her postdoctoral fellowship at the VA San Diego in the Mental Illness Research, Education, and Clinical Centers (MIRECC), with a focus on neuropsychological assessment and clinical research. She then joined the clinical faculty in the UCSD School of Medicine, as Program Director of the Senior Behavioral Health (SBH) Intensive Outpatient Program and an attending neuropsychologist on the SBH inpatient unit. Her clinical expertise is in conducting neuropsychological evaluations to help determine causes of neurological or cognitive problems. Dr. Nguyen is actively involved in clinical research. She has been the PI on several NIH and national/local foundation grants. Broadly, her research aims to identify mechanisms cognitive and biological aging in serious mental illnesses. Her current work is focused on the gut-brain axis and understanding the relationship between the gut microbiome and brain/behavior, particularly as it pertains to accelerated aging in mental illness but also in healthy aging. Dr. Nguyen was awarded an NIMH K23 Career Development Award to investigate the role of inflammation and the gut microbiome in schizophrenia and how imbalance of the gut ecosystem can alter immune responses, leading to alterations to brain and behavioral function.

    Collapse Research 
    Collapse Research Activities and Funding
    Characterizing the gut microbiome in schizophrenia: Relationship to age, cognition, & disease-related factors
    NIH/NIMH K23MH118435Jul 1, 2019 - Jun 30, 2023
    Role: Principal Investigator
    Inflammatory Correlates of Cognitive and Neural Heterogeneity in Schizophrenia
    APA Society for Clinical Neuropsychology Early Career Pilot Study Award Jul 1, 2016 - Jun 30, 2017
    Role: Principal Investigator
    Choline Intervention in Children with Fetal Alcohol Spectrum Disorders
    NIH/NIAAA F31AA021630Sep 10, 2012 - Sep 9, 2015
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Nguyen TT, Hathaway H, Kosciolek T, Knight R, Jeste DV. Gut microbiome in serious mental illnesses: A systematic review and critical evaluation. Schizophr Res. 2019 Sep 05. PMID: 31495702.
      View in: PubMed
    2. Tringale KR, Nguyen TT, Karunamuni R, Seibert T, Huynh-Le MP, Connor M, Moiseenko V, Gorman MK, Marshall A, Tibbs MD, Farid N, Simpson D, Sanghvi P, McDonald CR, Hattangadi-Gluth JA. Quantitative imaging biomarkers of damage to ritical memory regions associated with post-radiotherapy memory performance in brain tumor patients. Int J Radiat Oncol Biol Phys. 2019 Aug 10. PMID: 31408667.
      View in: PubMed
    3. Nguyen TT, Jeste DV. Positive light on schizophrenia and aging: Commentary on course and predictors of symptomatic remission in schizophrenia: A 5-year follow-up study in a Dutch psychiatric catchment area, by Lange et al. Schizophr Res. 2019 Jul 31. PMID: 31377051.
      View in: PubMed
    4. Tringale KR, Nguyen T, Bahrami N, Marshall DC, Leyden KM, Karunamuni R, Seibert TM, Kay Gorman M, Connor M, Burkeen J, Piccioni DE, Farid N, Hattangadi-Gluth JA, McDonald CR. Identifying early diffusion imaging biomarkers of regional white matter injury as indicators of executive function decline following brain radiotherapy: A prospective clinical trial in primary brain tumor patients. Radiother Oncol. 2019 Mar; 132:27-33. PMID: 30825966.
      View in: PubMed
    5. Nguyen TT, Kosciolek T, Maldonado Y, Daly RE, Martin AS, McDonald D, Knight R, Jeste DV. Differences in gut microbiome composition between persons with chronic schizophrenia and healthy comparison subjects. Schizophr Res. 2019 Feb; 204:23-29. PMID: 30268819.
      View in: PubMed
    6. McDonald D, Hyde E, Debelius JW, Morton JT, Gonzalez A, Ackermann G, Aksenov AA, Behsaz B, Brennan C, Chen Y, DeRight Goldasich L, Dorrestein PC, Dunn RR, Fahimipour AK, Gaffney J, Gilbert JA, Gogul G, Green JL, Hugenholtz P, Humphrey G, Huttenhower C, Jackson MA, Janssen S, Jeste DV, Jiang L, Kelley ST, Knights D, Kosciolek T, Ladau J, Leach J, Marotz C, Meleshko D, Melnik AV, Metcalf JL, Mohimani H, Montassier E, Navas-Molina J, Nguyen TT, Peddada S, Pevzner P, Pollard KS, Rahnavard G, Robbins-Pianka A, Sangwan N, Shorenstein J, Smarr L, Song SJ, Spector T, Swafford AD, Thackray VG, Thompson LR, Tripathi A, Vázquez-Baeza Y, Vrbanac A, Wischmeyer P, Wolfe E, Zhu Q, Knight R. American Gut: an Open Platform for Citizen Science Microbiome Research. mSystems. 2018 May-Jun; 3(3). PMID: 29795809.
      View in: PubMed
    7. Nguyen TT, Eyler LT, Jeste DV. Systemic Biomarkers of Accelerated Aging in Schizophrenia: A Critical Review and Future Directions. Schizophr Bull. 2018 02 15; 44(2):398-408. PMID: 29462455.
      View in: PubMed
    8. Nguyen TT, Kosciolek T, Eyler LT, Knight R, Jeste DV. Overview and systematic review of studies of microbiome in schizophrenia and bipolar disorder. J Psychiatr Res. 2018 04; 99:50-61. PMID: 29407287.
      View in: PubMed
    9. Nguyen TT, Dev SI, Chen G, Liou SC, Martin AS, Irwin MR, Carroll JE, Tu X, Jeste DV, Eyler LT. Abnormal levels of vascular endothelial biomarkers in schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2018 Dec; 268(8):849-860. PMID: 28942562.
      View in: PubMed
    10. Jeste DV, Nguyen TT. Successful Aging of Physicians. Am J Geriatr Psychiatry. 2018 02; 26(2):209-211. PMID: 28935514.
      View in: PubMed
    11. Dev SI, Nguyen TT, McKenna BS, Sutherland AN, Bartsch H, Theilmann RJ, Eyler LT. Steeper Slope of Age-Related Changes in White Matter Microstructure and Processing Speed in Bipolar Disorder. Am J Geriatr Psychiatry. 2017 Jul; 25(7):744-752. PMID: 28342644.
      View in: PubMed
    12. Seibert TM, Karunamuni R, Kaifi S, Burkeen J, Connor M, Krishnan AP, White NS, Farid N, Bartsch H, Murzin V, Nguyen TT, Moiseenko V, Brewer JB, McDonald CR, Dale AM, Hattangadi-Gluth JA. Cerebral Cortex Regions Selectively Vulnerable to Radiation Dose-Dependent Atrophy. Int J Radiat Oncol Biol Phys. 2017 04 01; 97(5):910-918. PMID: 28333012.
      View in: PubMed
    13. Nguyen TT, Risbud RD, Mattson SN, Chambers CD, Thomas JD. Randomized, double-blind, placebo-controlled clinical trial of choline supplementation in school-aged children with fetal alcohol spectrum disorders. Am J Clin Nutr. 2016 12; 104(6):1683-1692. PMID: 27806977.
      View in: PubMed
    14. Nguyen TT, Kovacevic S, Dev SI, Lu K, Liu TT, Eyler LT. Dynamic functional connectivity in bipolar disorder is associated with executive function and processing speed: A preliminary study. Neuropsychology. 2017 01; 31(1):73-83. PMID: 27775400.
      View in: PubMed
    15. Nguyen TT, Risbud RD, Chambers CD, Thomas JD. Dietary Nutrient Intake in School-Aged Children With Heavy Prenatal Alcohol Exposure. Alcohol Clin Exp Res. 2016 05; 40(5):1075-82. PMID: 27012806.
      View in: PubMed
    16. Simmons RW, Nguyen TT, Thomas JD, Riley EP. The Use of Open- and Closed-Loop Control During Goal-Directed Force Responses by Children with Heavy Prenatal Alcohol Exposure. Alcohol Clin Exp Res. 2015 Sep; 39(9):1814-22. PMID: 26248225; PMCID: PMC4558327.
    17. Infante MA, Moore EM, Nguyen TT, Fourligas N, Mattson SN, Riley EP. Objective assessment of ADHD core symptoms in children with heavy prenatal alcohol exposure. Physiol Behav. 2015 Sep 01; 148:45-50. PMID: 25447751; PMCID: PMC4408220.
    18. Nguyen TT, Glass L, Coles CD, Kable JA, May PA, Kalberg WO, Sowell ER, Jones KL, Riley EP, Mattson SN. The clinical utility and specificity of parent report of executive function among children with prenatal alcohol exposure. J Int Neuropsychol Soc. 2014 Aug; 20(7):704-16. PMID: 25033032; PMCID: PMC4228981.
    19. Nguyen TT, Ashrafi A, Thomas JD, Riley EP, Simmons RW. Children with heavy prenatal alcohol exposure have different frequency domain signal characteristics when producing isometric force. Neurotoxicol Teratol. 2013 Jan-Feb; 35:14-20. PMID: 23238099; PMCID: PMC3603370.
    20. Nguyen TT, Levy SS, Riley EP, Thomas JD, Simmons RW. Children with heavy prenatal alcohol exposure experience reduced control of isotonic force. Alcohol Clin Exp Res. 2013 Feb; 37(2):315-24. PMID: 22834891; PMCID: PMC3752030.
    21. Simmons RW, Nguyen TT, Levy SS, Thomas JD, Mattson SN, Riley EP. Children with heavy prenatal alcohol exposure exhibit deficits when regulating isometric force. Alcohol Clin Exp Res. 2012 Feb; 36(2):302-9. PMID: 22014260; PMCID: PMC3578740.
    22. Mattson SN, Crocker N, Nguyen TT. Fetal alcohol spectrum disorders: neuropsychological and behavioral features. Neuropsychol Rev. 2011 Jun; 21(2):81-101. PMID: 21503685; PMCID: PMC3410672.