Tannishtha Reya

Title(s)Professor, Pharmacology and Medicine
SchoolHealth Sciences
Address9500 Gilman Drive #0695
La Jolla CA 92093
Phone858-534-6568
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    Other Positions
    Title(s)Pharmacology and Medicine


    Collapse Biography 
    Collapse Education and Training
    Williams CollegeB.A.Biology
    University of PennsylvaniaPh.D.Immunology
    University of California San FranciscoPost-Doctoral FellowshipImmunology
    Stanford UniversityPost-Doctoral FellowshipStem Cell Biology
    Collapse Awards and Honors
    2020Ruth Leff Siegel Award for Pancreatic Cancer Research (Columbia University)
    2020Frederick W. Alt Award for New Discoveries in Immunology (Cancer Research Institute)
    2015NCI Outstanding Investigator Award
    2009NIH Director's Pioneer Award
    2008Richard E. Weitzman Memorial Award (Endocrine Society)
    2007Leukemia and Lymphoma Society Scholar Award
    2005The Presidential Early Career Award for Scientists and Engineers (PECASE, US Govt.)

    Collapse Overview 
    Collapse Overview
    The primary goal of our lab is to understand the signaling pathways that regulate the choice between stem cell renewal and commitment, and define how the same signals are subverted in cancer. The lab has three primary areas of interest: analyzing the role of developmental signals in stem cells and cancer, defining mechanisms that initiate stem cell regeneration after injury and developing high-resolution imaging strategies to visualize the behavior of living stem cells during growth, regeneration, and can¬cer formation. These studies have implications not only for understanding the basic mechanisms that regulate normal and oncogenic self-renewal, but also for enhancing stem cell based therapies for human disease.

    Collapse Research 
    Collapse Research Activities and Funding
    Reprogramming human stem cells for blood cell generation
    CIRM DISC1-10074Jul 1, 2017 - Jun 30, 2018
    Role: Principal Investigator
    Reprogramming Transcriptional Circuitry to Control Pancreatic Cancer
    Stand Up to Cancer/AACR/CRUK/Lustgarten Jan 31, 2016 - Dec 31, 2018
    Role: Senior Investigator
    Molecular strategies for early detection and targeting of cancer
    NIH R35CA197699Aug 12, 2015 - Jul 31, 2028
    Role: Principal Investigator
    Musashi-mediated control of pancreatic cancer growth and progression
    NIH R01CA186043Feb 1, 2015 - Jan 31, 2021
    Role: Principal Investigator
    Molecular Determinants of Asymmetric Division
    NIH R01DK099335Apr 1, 2014 - Mar 31, 2019
    Role: Principal Investigator
    Imaging self-renewal and transformation in hematopoietic stem cells
    NIH DP1CA174422Sep 30, 2009 - Jul 31, 2015
    Role: Principal Investigator
    Imaging self-renewal and transformation in hematopoietic stem cells
    NIH DP1OD006430Sep 30, 2009 - Jul 31, 2014
    Role: Principal Investigator
    Imaging the stem cell niche in regeneration and cancer
    NIH R01HL097767Sep 5, 2009 - Jul 31, 2013
    Role: Principal Investigator
    Damage and regeneration in the hematopoietic system
    NIH R01DK072234May 15, 2006 - Apr 30, 2010
    Role: Principal Investigator
    Centers for Medical Countermeasures Against Radiation
    NIH U19AI067798Aug 31, 2005 - Jul 31, 2020
    Role: Co-Investigator
    Regulation of Hematopoietic Stem Cell Self-Renewal
    NIH R01DK063031Apr 1, 2003 - Jul 31, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Author Correction: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. Nature. 2021 Dec; 600(7889):E18. Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, Woo G, Fang L, Santisakultarm TP, Manor U, Xu R, Becerra CR, Borazanci E, Von Hoff DD, Grandgenett PM, Hollingsworth MA, Leblanc M, Umetsu SE, Collisson EA, Scadeng M, Lowy AM, Donahue TR, Reya T, Downes M, Evans RM, Wahl GM, Pawson T, Tian R, Hunter T. PMID: 34848876.
      View in: PubMed   Mentions:
    2. Hematopoietic Stem Cells and Regeneration. Cold Spring Harb Perspect Biol. 2021 Nov 08. Biermann M, Reya T. PMID: 34750175.
      View in: PubMed   Mentions:
    3. The Role of the Microenvironment and Immune System in Regulating Stem Cell Fate in Cancer. Trends Cancer. 2021 07; 7(7):624-634. Ferguson LP, Diaz E, Reya T. PMID: 33509688; PMCID: PMC8318571.
      View in: PubMed   Mentions:    Fields:    
    4. A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia. Nat Commun. 2020 11 26; 11(1):5998. Spinler K, Bajaj J, Ito T, Zimdahl B, Hamilton M, Ahmadi A, Koechlein CS, Lytle N, Kwon HY, Anower-E-Khuda F, Sun H, Blevins A, Weeks J, Kritzik M, Karlseder J, Ginsberg MH, Park PW, Esko JD, Reya T. PMID: 33243988; PMCID: PMC7691523.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    5. AMD1 is required for the maintenance of leukemic stem cells and promotes chronic myeloid leukemic growth. Oncogene. 2021 01; 40(3):603-617. Sari IN, Yang YG, Wijaya YT, Jun N, Lee S, Kim KS, Bajaj J, Oehler VG, Kim SH, Choi SY, Park SH, Kim DW, Reya T, Han J, Kwon HY. PMID: 33203990.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. MARCH Proteins Mediate Responses to Antitumor Antibodies. J Immunol. 2020 11 15; 205(10):2883-2892. Ablack JN, Ortiz J, Bajaj J, Trinh K, Lagarrigue F, Cantor JM, Reya T, Ginsberg MH. PMID: 33077644.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas. Cancer Res. 2020 10 15; 80(20):4324-4334. Lenkiewicz E, Malasi S, Hogenson TL, Flores LF, Barham W, Phillips WJ, Roesler AS, Chambers KR, Rajbhandari N, Hayashi A, Antal CE, Downes M, Grandgenett PM, Hollingsworth MA, Cridebring D, Xiong Y, Lee JH, Ye Z, Yan H, Hernandez MC, Leiting JL, Evans RM, Ordog T, Truty MJ, Borad MJ, Reya T, Von Hoff DD, Fernandez-Zapico ME, Barrett MT. PMID: 32928922; PMCID: PMC7906529.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    8. An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia. Nature Cancer. 2020; 1(4):410-422. Bajaj J, Hamilton M, Shima Y, Chambers K, Spinler K, Van Nostrand EL, Yee B, Blue SM, Chen M, Rizzeri D, Chuah C, Oehler V, Broome EH, Sasik R, Scott-Browne J, Rao A, Yeo GW, Reya T.
    9. An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia. Nat Cancer. 2020 Apr; 1(4):410-422. Bajaj J, Hamilton M, Shima Y, Chambers K, Spinler K, Van Nostrand EL, Yee BA, Blue SM, Chen M, Rizzeri D, Chuah C, Oehler VG, Broome HE, Sasik R, Scott-Browne J, Rao A, Yeo GW, Reya T. PMID: 34109316; PMCID: PMC8186448.
      View in: PubMed   Mentions: 2  
    10. Stem cells in cancer initiation and progression. J Cell Biol. 2020 01 06; 219(1). Bajaj J, Diaz E, Reya T. PMID: 31874116; PMCID: PMC7039188.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    11. Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. Nature. 2019 05; 569(7754):131-135. Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, Woo G, Fang L, Santisakultarm TP, Manor U, Xu R, Becerra CR, Borazanci E, Von Hoff DD, Grandgenett PM, Hollingsworth MA, Leblanc M, Umetsu SE, Collisson EA, Scadeng M, Lowy AM, Donahue TR, Reya T, Downes M, Evans RM, Wahl GM, Pawson T, Tian R, Hunter T. PMID: 30996350; PMCID: PMC6565370.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    12. A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma. Cell. 2019 04 18; 177(3):572-586.e22. Lytle NK, Ferguson LP, Rajbhandari N, Gilroy K, Fox RG, Deshpande A, Schürch CM, Hamilton M, Robertson N, Lin W, Noel P, Wartenberg M, Zlobec I, Eichmann M, Galván JA, Karamitopoulou E, Gilderman T, Esparza LA, Shima Y, Spahn P, French R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik M, Von Hoff D, Han H, Ideker T, Deshpande AJ, Lowy AM, Adams PD, Reya T. PMID: 30955884; PMCID: PMC6711371.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    13. Stem cell fate in cancer growth, progression and therapy resistance. Nat Rev Cancer. 2018 11; 18(11):669-680. Lytle NK, Barber AG, Reya T. PMID: 30228301; PMCID: PMC8388042.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansCells
    14. Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State Plasticity. Cancer Cell. 2018 09 10; 34(3):466-482.e6. Dravis C, Chung CY, Lytle NK, Herrera-Valdez J, Luna G, Trejo CL, Reya T, Wahl GM. PMID: 30174241; PMCID: PMC6152943.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    15. Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas. Cancer Cell. 2017 Dec 11; 32(6):824-839.e8. Todoric J, Antonucci L, Di Caro G, Li N, Wu X, Lytle NK, Dhar D, Banerjee S, Fagman JB, Browne CD, Umemura A, Valasek MA, Kessler H, Tarin D, Goggins M, Reya T, Diaz-Meco M, Moscat J, Karin M. PMID: 29153842; PMCID: PMC5730340.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    16. Glucose feeds the TCA cycle via circulating lactate. Nature. 2017 11 02; 551(7678):115-118. Hui S, Ghergurovich JM, Morscher RJ, Jang C, Teng X, Lu W, Esparza LA, Reya T, Yanxiang Guo J, White E, Rabinowitz JD. PMID: 29045397; PMCID: PMC5898814.
      View in: PubMed   Mentions: 289     Fields:    Translation:AnimalsCells
    17. CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia. Cancer Cell. 2016 Nov 14; 30(5):792-805. Bajaj J, Konuma T, Lytle NK, Kwon HY, Ablack JN, Cantor JM, Rizzieri D, Chuah C, Oehler VG, Broome EH, Ball ED, van der Horst EH, Ginsberg MH, Reya T. PMID: 27908736; PMCID: PMC5137811.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    18. Delayed Onset of Symptoms Through Feedback Interference in Chronic Cancers. Converg Sci Phys Oncol. 2016; 2(4). Haney S, Reya T, Bazhenov M. PMID: 29744132; PMCID: PMC5937283.
      View in: PubMed   Mentions: 1  
    19. High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo. Nat Commun. 2016 07 18; 7:12169. Koechlein CS, Harris JR, Lee TK, Weeks J, Fox RG, Zimdahl B, Ito T, Blevins A, Jung SH, Chute JP, Chourasia A, Covert MW, Reya T. PMID: 27425143; PMCID: PMC4960315.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    20. Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. Nature. 2016 06 16; 534(7607):407-411. Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp J, Kritzik M, Sicklick J, Sander M, Grandgenett PM, Hollingsworth MA, Shibata S, Pizzo D, Valasek M, Sasik R, Scadeng M, Okano H, Kim Y, MacLeod AR, Lowy AM, Reya T. PMID: 27281208; PMCID: PMC4998062.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    21. Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia. Cell Stem Cell. 2015 Aug 06; 17(2):152-164. Kwon HY, Bajaj J, Ito T, Blevins A, Konuma T, Weeks J, Lytle NK, Koechlein CS, Rizzieri D, Chuah C, Oehler VG, Sasik R, Hardiman G, Reya T. PMID: 26212080; PMCID: PMC4664079.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    22. Fearful symmetry: subversion of asymmetric division in cancer development and progression. Cancer Res. 2015 Mar 01; 75(5):792-7. Bajaj J, Zimdahl B, Reya T. PMID: 25681272; PMCID: PMC4784538.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    23. Musashi signaling in stem cells and cancer. Annu Rev Cell Dev Biol. 2015; 31:249-67. Fox RG, Park FD, Koechlein CS, Kritzik M, Reya T. PMID: 26566113.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    24. Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade. Proc Natl Acad Sci U S A. 2014 Sep 23; 111(38):13870-5. Wu X, Zhang W, Font-Burgada J, Palmer T, Hamil AS, Biswas SK, Poidinger M, Borcherding N, Xie Q, Ellies LG, Lytle NK, Wu LW, Fox RG, Yang J, Dowdy SF, Reya T, Karin M. PMID: 25189770; PMCID: PMC4183333.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    25. Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration. Genes Dev. 2014 May 01; 28(9):995-1004. Lento W, Ito T, Zhao C, Harris JR, Huang W, Jiang C, Owzar K, Piryani S, Racioppi L, Chao N, Reya T. PMID: 24788518; PMCID: PMC4018497.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCellsPHPublic Health
    26. Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia. Nat Genet. 2014 Mar; 46(3):245-52. Zimdahl B, Ito T, Blevins A, Bajaj J, Konuma T, Weeks J, Koechlein CS, Kwon HY, Arami O, Rizzieri D, Broome HE, Chuah C, Oehler VG, Sasik R, Hardiman G, Reya T. PMID: 24487275; PMCID: PMC4267534.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    27. Wnt signaling in normal and malignant hematopoiesis. Cold Spring Harb Perspect Biol. 2013 Feb 01; 5(2). Lento W, Congdon K, Voermans C, Kritzik M, Reya T. PMID: 23378582; PMCID: PMC3552513.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    28. Pleiotrophin regulates the retention and self-renewal of hematopoietic stem cells in the bone marrow vascular niche. Cell Rep. 2012 Oct 25; 2(4):964-75. Himburg HA, Harris JR, Ito T, Daher P, Russell JL, Quarmyne M, Doan PL, Helms K, Nakamura M, Fixsen E, Herradon G, Reya T, Chao NJ, Harroch S, Chute JP. PMID: 23084748; PMCID: PMC3696585.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    29. Tannishtha Reya: classic pathways, new views on cancer. Interview by Caitlin Sedwick. J Cell Biol. 2012 Sep 03; 198(5):766-7. Reya T. PMID: 22945930; PMCID: PMC3432759.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. β-Arrestin2 mediates the initiation and progression of myeloid leukemia. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12532-7. Fereshteh M, Ito T, Kovacs JJ, Zhao C, Kwon HY, Tornini V, Konuma T, Chen M, Lefkowitz RJ, Reya T. PMID: 22773819; PMCID: PMC3411976.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    31. aSIRTing control over cancer stem cells. Cancer Cell. 2012 Feb 14; 21(2):140-2. Ito T, Zimdahl B, Reya T. PMID: 22340585.
      View in: PubMed   Mentions: 4     Fields:    
    32. Illuminating immune privilege--a role for regulatory T cells in preventing rejection. N Engl J Med. 2011 Sep 08; 365(10):956-7. Reya T. PMID: 21899457.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    33. Regulation of myeloid leukaemia by the cell-fate determinant Musashi. Nature. 2010 Aug 05; 466(7307):765-8. Ito T, Kwon HY, Zimdahl B, Congdon KL, Blum J, Lento WE, Zhao C, Lagoo A, Gerrard G, Foroni L, Goldman J, Goh H, Kim SH, Kim DW, Chuah C, Oehler VG, Radich JP, Jordan CT, Reya T. PMID: 20639863; PMCID: PMC2918284.
      View in: PubMed   Mentions: 157     Fields:    Translation:HumansAnimalsCells
    34. Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth. Cancer Cell. 2010 Apr 13; 17(4):388-99. Kim J, Tang JY, Gong R, Kim J, Lee JJ, Clemons KV, Chong CR, Chang KS, Fereshteh M, Gardner D, Reya T, Liu JO, Epstein EH, Stevens DA, Beachy PA. PMID: 20385363; PMCID: PMC4039177.
      View in: PubMed   Mentions: 186     Fields:    Translation:HumansAnimalsCells
    35. Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells. Nat Med. 2010 Apr; 16(4):475-82. Himburg HA, Muramoto GG, Daher P, Meadows SK, Russell JL, Doan P, Chi JT, Salter AB, Lento WE, Reya T, Chao NJ, Chute JP. PMID: 20305662; PMCID: PMC3689427.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansAnimalsCells
    36. Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia. Nature. 2009 Apr 09; 458(7239):776-9. Zhao C, Chen A, Jamieson CH, Fereshteh M, Abrahamsson A, Blum J, Kwon HY, Kim J, Chute JP, Rizzieri D, Munchhof M, VanArsdale T, Beachy PA, Reya T. PMID: 19169242; PMCID: PMC2946231.
      View in: PubMed   Mentions: 352     Fields:    Translation:HumansAnimalsCells
    37. Inhibition of apoptosome formation by suppression of Hsp90beta phosphorylation in tyrosine kinase-induced leukemias. Mol Cell Biol. 2008 Sep; 28(17):5494-506. Kurokawa M, Zhao C, Reya T, Kornbluth S. PMID: 18591256; PMCID: PMC2519729.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    38. Divide and conquer: how asymmetric division shapes cell fate in the hematopoietic system. Curr Opin Immunol. 2008 Jun; 20(3):302-7. Congdon KL, Reya T. PMID: 18554882; PMCID: PMC2560983.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    39. Activation of Wnt signaling in hematopoietic regeneration. Stem Cells. 2008 May; 26(5):1202-10. Congdon KL, Voermans C, Ferguson EC, DiMascio LN, Uqoezwa M, Zhao C, Reya T. PMID: 18308947.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    40. Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo. Cancer Cell. 2007 Dec; 12(6):528-41. Zhao C, Blum J, Chen A, Kwon HY, Jung SH, Cook JM, Lagoo A, Reya T. PMID: 18068630; PMCID: PMC2262869.
      View in: PubMed   Mentions: 264     Fields:    Translation:AnimalsCells
    41. Imaging hematopoietic precursor division in real time. Cell Stem Cell. 2007 Nov; 1(5):541-54. Wu M, Kwon HY, Rattis F, Blum J, Zhao C, Ashkenazi R, Jackson TL, Gaiano N, Oliver T, Reya T. PMID: 18345353; PMCID: PMC2267762.
      View in: PubMed   Mentions: 132     Fields:    Translation:AnimalsCells
    42. Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Mol Cell Biol. 2007 Jun; 27(12):4328-39. Zhao Y, Altman BJ, Coloff JL, Herman CE, Jacobs SR, Wieman HL, Wofford JA, Dimascio LN, Ilkayeva O, Kelekar A, Reya T, Rathmell JC. PMID: 17371841; PMCID: PMC1900055.
      View in: PubMed   Mentions: 94     Fields:    Translation:AnimalsCells
    43. Calmodulin-dependent protein kinase IV regulates hematopoietic stem cell maintenance. J Biol Chem. 2005 Sep 30; 280(39):33101-8. Kitsos CM, Sankar U, Illario M, Colomer-Font JM, Duncan AW, Ribar TJ, Reya T, Means AR. PMID: 16020540.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    44. Wnt signalling in stem cells and cancer. Nature. 2005 Apr 14; 434(7035):843-50. Reya T, Clevers H. PMID: 15829953.
      View in: PubMed   Mentions: 1395     Fields:    Translation:HumansAnimalsCells
    45. Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance. Nat Immunol. 2005 Mar; 6(3):314-22. Duncan AW, Rattis FM, DiMascio LN, Congdon KL, Pazianos G, Zhao C, Yoon K, Cook JM, Willert K, Gaiano N, Reya T. PMID: 15665828.
      View in: PubMed   Mentions: 298     Fields:    Translation:HumansAnimalsCells
    46. Frizzled 9 knock-out mice have abnormal B-cell development. Blood. 2005 Mar 15; 105(6):2487-94. Ranheim EA, Kwan HC, Reya T, Wang YK, Weissman IL, Francke U. PMID: 15572594.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    47. The elements of stem cell self-renewal: a genetic perspective. Biotechniques. 2003 Dec; 35(6):1240-7. Pazianos G, Uqoezwa M, Reya T. PMID: 14682059.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    48. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature. 2003 May 22; 423(6938):409-14. Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, Willert K, Hintz L, Nusse R, Weissman IL. PMID: 12717450.
      View in: PubMed   Mentions: 664     Fields:    Translation:AnimalsCells
    49. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature. 2003 May 22; 423(6938):448-52. Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, Yates JR, Nusse R. PMID: 12717451.
      View in: PubMed   Mentions: 731     Fields:    Translation:AnimalsCells
    50. Stem cells, cancer, and cancer stem cells. Nature. 2001 Nov 01; 414(6859):105-11. Reya T, Morrison SJ, Clarke MF, Weissman IL. PMID: 11689955.
      View in: PubMed   Mentions: 3360     Fields:    Translation:HumansAnimalsCells
    51. Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity. 2000 Jul; 13(1):15-24. Reya T, O'Riordan M, Okamura R, Devaney E, Willert K, Nusse R, Grosschedl R. PMID: 10933391.
      View in: PubMed   Mentions: 143     Fields:    Translation:AnimalsCells
    52. Lymphoid precursors. Curr Opin Immunol. 2000 Apr; 12(2):144-50. Akashi K, Reya T, Dalma-Weiszhausz D, Weissman IL. PMID: 10712944.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    53. Control of lymphocyte differentiation by the LEF-1/TCF family of transcription factors. Cold Spring Harb Symp Quant Biol. 1999; 64:133-40. Reya T, Okamura R, Grosschedl R. PMID: 11232278.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    54. Mechanisms of intestinal epithelial cell injury and colitis in interleukin 2 (IL2)-deficient mice. Cell Immunol. 1998 Jul 10; 187(1):52-66. Baumgart DC, Olivier WA, Reya T, Peritt D, Rombeau JL, Carding SR. PMID: 9682004.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    55. Abnormal myelocytic cell development in interleukin-2 (IL-2)-deficient mice: evidence for the involvement of IL-2 in myelopoiesis. Blood. 1998 Apr 15; 91(8):2935-47. Reya T, Contractor NV, Couzens MS, Wasik MA, Emerson SG, Carding SR. PMID: 9531604.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    56. Transcriptional regulation of B-cell differentiation. Curr Opin Immunol. 1998 Apr; 10(2):158-65. Reya T, Grosschedl R. PMID: 9602304.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    57. Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficient mice. J Immunol. 1998 Jan 01; 160(1):385-94. Contractor NV, Bassiri H, Reya T, Park AY, Baumgart DC, Wasik MA, Emerson SG, Carding SR. PMID: 9551995.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    58. Thymic stromal-cell abnormalities and dysregulated T-cell development in IL-2-deficient mice. Dev Immunol. 1998; 5(4):287-302. Reya T, Bassiri H, Biancaniello R, Carding SR. PMID: 9814585; PMCID: PMC2275991.
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