Somaira Nowsheen

Title(s)Resident Physician, Dermatology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A ribosomal gene panel predicting a novel synthetic lethality in non-BRCAness tumors. Signal Transduct Target Ther. 2023 05 10; 8(1):183. Zhang C, Guo Q, Chen L, Wu Z, Yan XJ, Zou C, Zhang Q, Tan J, Fang T, Rao Q, Li Y, Shen S, Deng M, Wang L, Gao H, Yu J, Li H, Zhang C, Nowsheen S, Kloeber J, Zhao F, Yin P, Teng C, Lin Z, Song K, Yao S, Yao L, Wu L, Zhang Y, Cheng X, Gao Q, Yuan J, Lou Z, Zhang JS. PMID: 37160887; PMCID: PMC10170152.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. DNA Repair Deficiency Regulates Immunity Response in Cancers: Molecular Mechanism and Approaches for Combining Immunotherapy. Cancers (Basel). 2023 Mar 06; 15(5). Xu Y, Nowsheen S, Deng M. PMID: 36900418; PMCID: PMC10000854.
      View in: PubMed   Mentions: 4  
    3. Correction to: USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization. Cell Death Differ. 2023 Mar; 30(3):857-858. Wu C, Luo K, Zhao F, Yin P, Song Y, Deng M, Huang J, Chen Y, Li L, Lee S, Kim J, Zhou Q, Tu X, Nowsheen S, Luo Q, Gao X, Lou Z, Liu Z, Yuan J. PMID: 36289447; PMCID: PMC9984370.
      View in: PubMed   Mentions: 1     Fields:    
    4. Author Correction: The bromodomain containing protein BRD-9 orchestrates RAD51-RAD54 complex formation and regulates homologous recombination-mediated repair. Nat Commun. 2022 Nov 23; 13(1):7190. Zhou Q, Huang J, Zhang C, Zhao F, Kim W, Tu X, Zhang Y, Nowsheen S, Zhu Q, Deng M, Chen Y, Qin B, Luo K, Liu B, Lou Z, Mutter RW, Yuan J. PMID: 36418323; PMCID: PMC9684546.
      View in: PubMed   Mentions:    Fields:    
    5. ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection. Nat Cell Biol. 2021 08; 23(8):894-904. Zhao F, Kim W, Gao H, Liu C, Zhang Y, Chen Y, Deng M, Zhou Q, Huang J, Hu Q, Chen SH, Nowsheen S, Kloeber JA, Qin B, Yin P, Tu X, Guo G, Qin S, Zhang C, Gao M, Luo K, Liu Y, Lou Z, Yuan J. PMID: 34354233.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    6. Cutaneous lupus erythematosus mimicking radiation dermatitis in a patient with breast cancer. JAAD Case Rep. 2021 Sep; 15:64-66. Nowsheen S, Crum O, Hughes S, Wentland AL. PMID: 34401433; PMCID: PMC8358281.
      View in: PubMed   Mentions:
    7. Dupilumab in the treatment of nasal polyposis: A retrospective, real-world study. Ann Allergy Asthma Immunol. 2021 09; 127(3):386-387. Nowsheen S, Darveaux JI. PMID: 34022386.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Real-world efficacy and safety of dupilumab use in the treatment of asthma. Ann Allergy Asthma Immunol. 2021 07; 127(1):147-149. Nowsheen S, Darveaux JI. PMID: 33848633.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    9. Peristomal pemphigoid: A single-center retrospective cohort study. J Am Acad Dermatol. 2022 01; 86(1):204-207. Nowsheen S, Wieland CN, Camilleri MJ, Gibson LE, Lehman JS. PMID: 33508392.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Disseminated intravascular coagulopathy: a complication of Stevens-Johnson syndrome/toxic epidermal necrolysis. Int J Dermatol. 2021 Feb; 60(2):185-189. El-Azhary RA, Nowsheen S, Gibson LE, DiCaudo DJ. PMID: 33332598.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Differences between Stevens-Johnson syndrome versus toxic epidermal necrolysis. Int J Dermatol. 2021 Jan; 60(1):53-59. Nowsheen S, Lehman JS, El-Azhary RA. PMID: 33252832.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Use of spironolactone to treat acne in adolescent females. Pediatr Dermatol. 2021 Jan; 38(1):72-76. Roberts EE, Nowsheen S, Davis DMR, Hand JL, Tollefson MM, Wetter DA. PMID: 33009838.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    13. Extracellular matrix stiffness determines DNA repair efficiency and cellular sensitivity to genotoxic agents. Sci Adv. 2020 09; 6(37). Deng M, Lin J, Nowsheen S, Liu T, Zhao Y, Villalta PW, Sicard D, Tschumperlin DJ, Lee S, Kim J, Lou Z. PMID: 32917705; PMCID: PMC7486107.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    14. Author Correction: Regulation of sister chromatid cohesion by nuclear PD-L1. Cell Res. 2020 Sep; 30(9):823. Yu J, Qin B, Moyer AM, Nowsheen S, Tu X, Dong H, Boughey JC, Goetz MP, Weinshilboum R, Lou Z, Wang L. PMID: 32636455; PMCID: PMC7608186.
      View in: PubMed   Mentions:    Fields:    
    15. Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging. Mol Cell. 2020 09 03; 79(5):824-835.e5. Huang J, Zhou Q, Gao M, Nowsheen S, Zhao F, Kim W, Zhu Q, Kojima Y, Yin P, Zhang Y, Guo G, Tu X, Deng M, Luo K, Qin B, Machida Y, Lou Z. PMID: 32649882; PMCID: PMC7484104.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    16. STK38 promotes ATM activation by acting as a reader of histone H4 ufmylation. Sci Adv. 2020 06; 6(23):eaax8214. Qin B, Yu J, Nowsheen S, Zhao F, Wang L, Lou Z. PMID: 32537488; PMCID: PMC7269669.
      View in: PubMed   Mentions: 15     Fields:    
    17. The bromodomain containing protein BRD-9 orchestrates RAD51-RAD54 complex formation and regulates homologous recombination-mediated repair. Nat Commun. 2020 05 26; 11(1):2639. Zhou Q, Huang J, Zhang C, Zhao F, Kim W, Tu X, Zhang Y, Nowsheen S, Zhu Q, Deng M, Chen Y, Qin B, Luo K, Liu B, Lou Z, Mutter RW, Yuan J. PMID: 32457312; PMCID: PMC7251110.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    18. Regulation of sister chromatid cohesion by nuclear PD-L1. Cell Res. 2020 07; 30(7):590-601. Yu J, Qin B, Moyer AM, Nowsheen S, Tu X, Dong H, Boughey JC, Goetz MP, Weinshilboum R, Lou Z, Wang L. PMID: 32350394; PMCID: PMC7343880.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    19. The role of poly(ADP-ribose) polymerase inhibitors in the treatment of cancer and methods to overcome resistance: a review. Cell Biosci. 2020; 10:35. Patel M, Nowsheen S, Maraboyina S, Xia F. PMID: 32180937; PMCID: PMC7065339.
      View in: PubMed   Mentions: 39  
    20. Treatment of acne with spironolactone: a retrospective review of 395 adult patients at Mayo Clinic, 2007-2017. J Eur Acad Dermatol Venereol. 2020 Sep; 34(9):2106-2110. Roberts EE, Nowsheen S, Davis MDP, McEvoy MT, Newman CC, Sartori Valinotti JC, Sciallis GF, Torgerson RR, Wetter DA. PMID: 32078195.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Utilization of Cardiac Surveillance Tests in Survivors of Breast Cancer and Lymphoma After Anthracycline-Based Chemotherapy. Circ Cardiovasc Qual Outcomes. 2020 03; 13(3):e005984. Ruddy KJ, Sangaralingham LR, Van Houten H, Nowsheen S, Sandhu N, Moslehi J, Neuman H, Jemal A, Haddad TC, Blaes AH, Villarraga HR, Thompson C, Shah ND, Herrmann J. PMID: 32106704; PMCID: PMC7101030.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    22. CHK2-FOXK axis promotes transcriptional control of autophagy programs. Sci Adv. 2020 01; 6(1):eaax5819. Chen Y, Wu J, Liang G, Geng G, Zhao F, Yin P, Nowsheen S, Wu C, Li Y, Li L, Kim W, Zhou Q, Huang J, Liu J, Zhang C, Guo G, Deng M, Tu X, Gao X, Liu Z, Chen Y, Lou Z, Luo K, Yuan J. PMID: 31911943; PMCID: PMC6938702.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    23. ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex. Nat Commun. 2019 11 22; 10(1):5304. Kim W, Zhao F, Wu R, Qin S, Nowsheen S, Huang J, Zhou Q, Chen Y, Deng M, Guo G, Luo K, Lou Z, Yuan J. PMID: 31757956; PMCID: PMC6876566.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    24. Melanoma in a patient with previously unrecognized Birt-Hogg-Dubé syndrome. JAAD Case Rep. 2019 Nov; 5(11):947-952. Nowsheen S, Hand JL, Gibson LE, El-Azhary RA. PMID: 31687461; PMCID: PMC6820253.
      View in: PubMed   Mentions: 1  
    25. The AMPK-Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome. Nat Cell Biol. 2019 08; 21(8):940-951. Lee SB, Kim JJ, Han SA, Fan Y, Guo LS, Aziz K, Nowsheen S, Kim SS, Park SY, Luo Q, Chung JO, Choi SI, Aziz A, Yin P, Tong SY, Fiesel FC, Springer W, Zhang JS, Lou Z. PMID: 31358971; PMCID: PMC6679774.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    26. Adalimumab-induced erythrodermic reactions. Int J Dermatol. 2019 Oct; 58(10):e204-e206. Nowsheen S, Kohorst JJ, El-Azhary RA. PMID: 31135963.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    27. A novel UCHL3 inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homologous recombination-mediated DNA double strand break repair. Cell Death Dis. 2019 05 21; 10(6):398. Song Z, Tu X, Zhou Q, Huang J, Chen Y, Liu J, Lee S, Kim W, Nowsheen S, Luo K, Yuan J, Lou Z. PMID: 31113933; PMCID: PMC6529448.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    28. PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy. Mol Cell. 2019 06 20; 74(6):1215-1226.e4. Tu X, Qin B, Zhang Y, Zhang C, Kahila M, Nowsheen S, Yin P, Yuan J, Pei H, Li H, Yu J, Song Z, Zhou Q, Zhao F, Liu J, Zhang C, Dong H, Mutter RW, Lou Z. PMID: 31053471; PMCID: PMC6737939.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    29. UFL1 promotes histone H4 ufmylation and ATM activation. Nat Commun. 2019 03 18; 10(1):1242. Qin B, Yu J, Nowsheen S, Wang M, Tu X, Liu T, Li H, Wang L, Lou Z. PMID: 30886146; PMCID: PMC6423285.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    30. Chemotherapy-induced skin toxicity and capillary leak syndrome. Int J Dermatol. 2019 Jul; 58(7):856-860. Hunjan MK, Nowsheen S, Ramos-Rodriguez AJ, Bridges AG, Lehman JS, Hashmi SK, El-Azhary RA. PMID: 30847892.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2. Cancer Lett. 2019 05 01; 449:114-124. Wu J, Chen Y, Geng G, Li L, Yin P, Nowsheen S, Li Y, Wu C, Liu J, Zhao F, Kim W, Zhou Q, Huang J, Guo G, Zhang C, Tu X, Gao X, Lou Z, Luo K, Qiao H, Yuan J. PMID: 30771428.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    32. Clinical and histopathological spectrum of toxic erythema of chemotherapy in patients who have undergone allogeneic hematopoietic cell transplantation. Hematol Oncol Stem Cell Ther. 2019 Mar; 12(1):19-25. Hunjan MK, Nowsheen S, Ramos-Rodriguez AJ, Hashmi SK, Bridges AG, Lehman JS, El-Azhary R. PMID: 30248313.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Trastuzumab in Female Breast Cancer Patients With Reduced Left Ventricular Ejection Fraction. J Am Heart Assoc. 2018 08 07; 7(15):e008637. Nowsheen S, Aziz K, Park JY, Lerman A, Villarraga HR, Ruddy KJ, Herrmann J. PMID: 30371238; PMCID: PMC6201446.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    34. ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage. Nat Commun. 2018 07 16; 9(1):2736. Nowsheen S, Aziz K, Luo K, Deng M, Qin B, Yuan J, Jeganathan KB, Yu J, Zhang H, Ding W, van Deursen JM, Lou Z. PMID: 30013081; PMCID: PMC6048040.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    35. USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization. Cell Death Differ. 2018 11; 25(10):1855-1869. Wu C, Luo K, Zhao F, Yin P, Song Y, Deng M, Huang J, Chen Y, Li L, Lee S, Kim J, Zhou Q, Tu X, Nowsheen S, Luo Q, Gao X, Lou Z, Liu Z, Yuan J. PMID: 29867130; PMCID: PMC6180113.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    36. Calling RNF168 to action. Cell Stress. 2018 May 10; 2(5):113-114. Nowsheen S, Lou Z. PMID: 31225475; PMCID: PMC6551701.
      View in: PubMed   Mentions: 3  
    37. DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine. J Clin Invest. 2018 06 01; 128(6):2376-2388. Yu J, Qin B, Moyer AM, Nowsheen S, Liu T, Qin S, Zhuang Y, Liu D, Lu SW, Kalari KR, Visscher DW, Copland JA, McLaughlin SA, Moreno-Aspitia A, Northfelt DW, Gray RJ, Lou Z, Suman VJ, Weinshilboum R, Boughey JC, Goetz MP, Wang L. PMID: 29708513; PMCID: PMC5983332.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    38. Preventing Today's Survivors of Breast Cancer From Becoming Tomorrow's Cardiac Patients. J Oncol Pract. 2018 04; 14(4):213-214. Nowsheen S, Duma N, Ruddy KJ. PMID: 29641946.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Synthetic Lethality of PARP Inhibition and Ionizing Radiation is p53-dependent. Mol Cancer Res. 2018 07; 16(7):1092-1102. Sizemore ST, Mohammad R, Sizemore GM, Nowsheen S, Yu H, Ostrowski MC, Chakravarti A, Xia F. PMID: 29592899; PMCID: PMC6713455.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    40. L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage. Nat Cell Biol. 2018 04; 20(4):455-464. Nowsheen S, Aziz K, Aziz A, Deng M, Qin B, Luo K, Jeganathan KB, Zhang H, Liu T, Yu J, Deng Y, Yuan J, Ding W, van Deursen JM, Lou Z. PMID: 29581593; PMCID: PMC6083879.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    41. Cardiovascular Concerns in BRCA1 and BRCA2 Mutation Carriers. Curr Treat Options Cardiovasc Med. 2018 Mar 01; 20(2):18. Gast KC, Viscuse PV, Nowsheen S, Haddad TC, Mutter RW, Wahner Hendrickson AE, Couch FJ, Ruddy KJ. PMID: 29497862.
      View in: PubMed   Mentions: 4  
    42. The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization. Oncogene. 2018 05; 37(18):2422-2431. Li L, Liu T, Li Y, Wu C, Luo K, Yin Y, Chen Y, Nowsheen S, Wu J, Lou Z, Yuan J. PMID: 29449692; PMCID: PMC5940338.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    43. Chk1 inhibitor SCH 900776 enhances the antitumor activity of MLN4924 on pancreatic cancer. Cell Cycle. 2018; 17(2):191-199. Li JA, Song C, Rong Y, Kuang T, Wang D, Xu X, Yuan J, Luo K, Qin B, Nowsheen S, Lou Z, Lou W. PMID: 29157102; PMCID: PMC5884359.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    44. Complex DNA Damage: A Route to Radiation-Induced Genomic Instability and Carcinogenesis. Cancers (Basel). 2017 Jul 18; 9(7). Mavragani IV, Nikitaki Z, Souli MP, Aziz A, Nowsheen S, Aziz K, Rogakou E, Georgakilas AG. PMID: 28718816; PMCID: PMC5532627.
      View in: PubMed   Mentions: 62  
    45. Incidence, Diagnosis, and Treatment of Cardiac Toxicity from Trastuzumab in Patients with Breast Cancer. Curr Breast Cancer Rep. 2017 Sep; 9(3):173-182. Nowsheen S, Viscuse PV, O'Sullivan CC, Sandhu NP, Haddad TC, Blaes A, Klemp J, Nhola L, Herrmann J, Ruddy KJ. PMID: 29225726; PMCID: PMC5718359.
      View in: PubMed   Mentions: 11  
    46. USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response. Nat Commun. 2017 06 01; 8:15752. Li Y, Luo K, Yin Y, Wu C, Deng M, Li L, Chen Y, Nowsheen S, Lou Z, Yuan J. PMID: 28569838; PMCID: PMC5461494.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    47. USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling. EMBO J. 2017 05 15; 36(10):1434-1446. Luo K, Li Y, Yin Y, Li L, Wu C, Chen Y, Nowsheen S, Hu Q, Zhang L, Lou Z, Yuan J. PMID: 28363942; PMCID: PMC5430216.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    48. Regulation of Serine-Threonine Kinase Akt Activation by NAD+-Dependent Deacetylase SIRT7. Cell Rep. 2017 01 31; 18(5):1229-1240. Yu J, Qin B, Wu F, Qin S, Nowsheen S, Shan S, Zayas J, Pei H, Lou Z, Wang L. PMID: 28147277; PMCID: PMC5298804.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    49. CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1. Nat Commun. 2017 01 09; 8:13923. Liu T, Yu J, Deng M, Yin Y, Zhang H, Luo K, Qin B, Li Y, Wu C, Ren T, Han Y, Yin P, Kim J, Lee S, Lin J, Zhang L, Zhang J, Nowsheen S, Wang L, Boughey J, Goetz MP, Yuan J, Lou Z. PMID: 28067227; PMCID: PMC5228031.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    50. A phosphorylation-deubiquitination cascade regulates the BRCA2-RAD51 axis in homologous recombination. Genes Dev. 2016 12 01; 30(23):2581-2595. Luo K, Li L, Li Y, Wu C, Yin Y, Chen Y, Deng M, Nowsheen S, Yuan J, Lou Z. PMID: 27941124; PMCID: PMC5204351.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    51. Failure to detect DNA-guided genome editing using Natronobacterium gregoryi Argonaute. Nat Biotechnol. 2016 11 28; 35(1):17-18. Lee SH, Turchiano G, Ata H, Nowsheen S, Romito M, Lou Z, Ryu SM, Ekker SC, Cathomen T, Kim JS. PMID: 27893702; PMCID: PMC5662444.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    52. Designing a broad-spectrum integrative approach for cancer prevention and treatment. Semin Cancer Biol. 2015 Dec; 35 Suppl:S276-S304. Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HPV, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HMC, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo M. PMID: 26590477; PMCID: PMC4819002.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    53. A multi-targeted approach to suppress tumor-promoting inflammation. Semin Cancer Biol. 2015 Dec; 35 Suppl:S151-S184. Samadi AK, Bilsland A, Georgakilas AG, Amedei A, Amin A, Bishayee A, Azmi AS, Lokeshwar BL, Grue B, Panis C, Boosani CS, Poudyal D, Stafforini DM, Bhakta D, Niccolai E, Guha G, Vasantha Rupasinghe HP, Fujii H, Honoki K, Mehta K, Aquilano K, Lowe L, Hofseth LJ, Ricciardiello L, Ciriolo MR, Singh N, Whelan RL, Chaturvedi R, Ashraf SS, Shantha Kumara HMC, Nowsheen S, Mohammed SI, Keith WN, Helferich WG, Yang X. PMID: 25951989; PMCID: PMC4635070.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    54. Broad targeting of resistance to apoptosis in cancer. Semin Cancer Biol. 2015 Dec; 35 Suppl:S78-S103. Mohammad RM, Muqbil I, Lowe L, Yedjou C, Hsu HY, Lin LT, Siegelin MD, Fimognari C, Kumar NB, Dou QP, Yang H, Samadi AK, Russo GL, Spagnuolo C, Ray SK, Chakrabarti M, Morre JD, Coley HM, Honoki K, Fujii H, Georgakilas AG, Amedei A, Niccolai E, Amin A, Ashraf SS, Helferich WG, Yang X, Boosani CS, Guha G, Bhakta D, Ciriolo MR, Aquilano K, Chen S, Mohammed SI, Keith WN, Bilsland A, Halicka D, Nowsheen S, Azmi AS. PMID: 25936818; PMCID: PMC4720504.
      View in: PubMed   Mentions: 276     Fields:    Translation:HumansCells
    55. Sustained proliferation in cancer: Mechanisms and novel therapeutic targets. Semin Cancer Biol. 2015 Dec; 35 Suppl:S25-S54. Feitelson MA, Arzumanyan A, Kulathinal RJ, Blain SW, Holcombe RF, Mahajna J, Marino M, Martinez-Chantar ML, Nawroth R, Sanchez-Garcia I, Sharma D, Saxena NK, Singh N, Vlachostergios PJ, Guo S, Honoki K, Fujii H, Georgakilas AG, Bilsland A, Amedei A, Niccolai E, Amin A, Ashraf SS, Boosani CS, Guha G, Ciriolo MR, Aquilano K, Chen S, Mohammed SI, Azmi AS, Bhakta D, Halicka D, Keith WN, Nowsheen S. PMID: 25892662; PMCID: PMC4898971.
      View in: PubMed   Mentions: 223     Fields:    Translation:HumansCells
    56. Therapeutic targeting of replicative immortality. Semin Cancer Biol. 2015 Dec; 35 Suppl:S104-S128. Yaswen P, MacKenzie KL, Keith WN, Hentosh P, Rodier F, Zhu J, Firestone GL, Matheu A, Carnero A, Bilsland A, Sundin T, Honoki K, Fujii H, Georgakilas AG, Amedei A, Amin A, Helferich B, Boosani CS, Guha G, Ciriolo MR, Chen S, Mohammed SI, Azmi AS, Bhakta D, Halicka D, Niccolai E, Aquilano K, Ashraf SS, Nowsheen S, Yang X. PMID: 25869441; PMCID: PMC4600408.
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    57. Cancer prevention and therapy through the modulation of the tumor microenvironment. Semin Cancer Biol. 2015 Dec; 35 Suppl:S199-S223. Casey SC, Amedei A, Aquilano K, Azmi AS, Benencia F, Bhakta D, Bilsland AE, Boosani CS, Chen S, Ciriolo MR, Crawford S, Fujii H, Georgakilas AG, Guha G, Halicka D, Helferich WG, Heneberg P, Honoki K, Keith WN, Kerkar SP, Mohammed SI, Niccolai E, Nowsheen S, Vasantha Rupasinghe HP, Samadi A, Singh N, Talib WH, Venkateswaran V, Whelan RL, Yang X, Felsher DW. PMID: 25865775; PMCID: PMC4930000.
      View in: PubMed   Mentions: 163     Fields:    Translation:HumansCells
    58. Tissue invasion and metastasis: Molecular, biological and clinical perspectives. Semin Cancer Biol. 2015 Dec; 35 Suppl:S244-S275. Jiang WG, Sanders AJ, Katoh M, Ungefroren H, Gieseler F, Prince M, Thompson SK, Zollo M, Spano D, Dhawan P, Sliva D, Subbarayan PR, Sarkar M, Honoki K, Fujii H, Georgakilas AG, Amedei A, Niccolai E, Amin A, Ashraf SS, Ye L, Helferich WG, Yang X, Boosani CS, Guha G, Ciriolo MR, Aquilano K, Chen S, Azmi AS, Keith WN, Bilsland A, Bhakta D, Halicka D, Nowsheen S, Pantano F, Santini D. PMID: 25865774.
      View in: PubMed   Mentions: 216     Fields:    Translation:HumansCells
    59. Immune evasion in cancer: Mechanistic basis and therapeutic strategies. Semin Cancer Biol. 2015 Dec; 35 Suppl:S185-S198. Vinay DS, Ryan EP, Pawelec G, Talib WH, Stagg J, Elkord E, Lichtor T, Decker WK, Whelan RL, Kumara HMCS, Signori E, Honoki K, Georgakilas AG, Amin A, Helferich WG, Boosani CS, Guha G, Ciriolo MR, Chen S, Mohammed SI, Azmi AS, Keith WN, Bilsland A, Bhakta D, Halicka D, Fujii H, Aquilano K, Ashraf SS, Nowsheen S, Yang X, Choi BK, Kwon BS. PMID: 25818339.
      View in: PubMed   Mentions: 604     Fields:    Translation:HumansCells
    60. Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds. Semin Cancer Biol. 2015 Dec; 35 Suppl:S55-S77. Amin ARMR, Karpowicz PA, Carey TE, Arbiser J, Nahta R, Chen ZG, Dong JT, Kucuk O, Khan GN, Huang GS, Mi S, Lee HY, Reichrath J, Honoki K, Georgakilas AG, Amedei A, Amin A, Helferich B, Boosani CS, Ciriolo MR, Chen S, Mohammed SI, Azmi AS, Keith WN, Bhakta D, Halicka D, Niccolai E, Fujii H, Aquilano K, Ashraf SS, Nowsheen S, Yang X, Bilsland A, Shin DM. PMID: 25749195; PMCID: PMC4561219.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    61. Broad targeting of angiogenesis for cancer prevention and therapy. Semin Cancer Biol. 2015 Dec; 35 Suppl:S224-S243. Wang Z, Dabrosin C, Yin X, Fuster MM, Arreola A, Rathmell WK, Generali D, Nagaraju GP, El-Rayes B, Ribatti D, Chen YC, Honoki K, Fujii H, Georgakilas AG, Nowsheen S, Amedei A, Niccolai E, Amin A, Ashraf SS, Helferich B, Yang X, Guha G, Bhakta D, Ciriolo MR, Aquilano K, Chen S, Halicka D, Mohammed SI, Azmi AS, Bilsland A, Keith WN, Jensen LD. PMID: 25600295; PMCID: PMC4737670.
      View in: PubMed   Mentions: 187     Fields:    Translation:Humans
    62. Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6). FASEB J. 2015 Jan; 29(1):152-63. Mazzone A, Gibbons SJ, Bernard CE, Nowsheen S, Middha S, Almada LL, Ordog T, Kendrick ML, Reid Lombardo KM, Shen KR, Galietta LJ, Fernandez-Zapico ME, Farrugia G. PMID: 25351986; PMCID: PMC4285536.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    63. An ex vivo assay of XRT-induced Rad51 foci formation predicts response to PARP-inhibition in ovarian cancer. Gynecol Oncol. 2014 Aug; 134(2):331-7. Shah MM, Dobbin ZC, Nowsheen S, Wielgos M, Katre AA, Alvarez RD, Konstantinopoulos PA, Yang ES, Landen CN. PMID: 24844596; PMCID: PMC4221419.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    64. Toxicity and adverse effects of Tamoxifen and other anti-estrogen drugs. Pharmacol Ther. 2013 Sep; 139(3):392-404. Yang G, Nowsheen S, Aziz K, Georgakilas AG. PMID: 23711794.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsPHPublic Health
    65. Assaying DNA damage in hippocampal neurons using the comet assay. J Vis Exp. 2012 Dec 19; (70):e50049. Nowsheen S, Xia F, Yang ES. PMID: 23271144; PMCID: PMC3576424.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    66. Endoglin (CD105) contributes to platinum resistance and is a target for tumor-specific therapy in epithelial ovarian cancer. Clin Cancer Res. 2013 Jan 01; 19(1):170-82. Ziebarth AJ, Nowsheen S, Steg AD, Shah MM, Katre AA, Dobbin ZC, Han HD, Lopez-Berestein G, Sood AK, Conner M, Yang ES, Landen CN. PMID: 23147994; PMCID: PMC3537868.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    67. Synthetic lethal interactions between EGFR and PARP inhibition in human triple negative breast cancer cells. PLoS One. 2012; 7(10):e46614. Nowsheen S, Cooper T, Stanley JA, Yang ES. PMID: 23071597; PMCID: PMC3469581.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    68. The intersection between DNA damage response and cell death pathways. Exp Oncol. 2012 Oct; 34(3):243-54. Nowsheen S, Yang ES. PMID: 23070009; PMCID: PMC3754840.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    69. HER2 overexpression renders human breast cancers sensitive to PARP inhibition independently of any defect in homologous recombination DNA repair. Cancer Res. 2012 Sep 15; 72(18):4796-806. Nowsheen S, Cooper T, Bonner JA, LoBuglio AF, Yang ES. PMID: 22987487; PMCID: PMC3458582.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    70. Targeting BRCA1 localization to augment breast tumor sensitivity to poly(ADP-Ribose) polymerase inhibition. Cancer Res. 2012 Nov 01; 72(21):5547-55. Yang ES, Nowsheen S, Rahman MA, Cook RS, Xia F. PMID: 22962264; PMCID: PMC3771348.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    71. Biomarkers to assess the targeting of DNA repair pathways to augment tumor response to therapy. Curr Mol Med. 2012 Jul 01; 12(6):788-803. Nowsheen S, Whitley AC, Yang ES. PMID: 22292444.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    72. The interplay between inflammation and oxidative stress in carcinogenesis. Curr Mol Med. 2012 Jul 01; 12(6):672-80. Nowsheen S, Aziz K, Kryston TB, Ferguson NF, Georgakilas A. PMID: 22292435.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    73. Epigenetic inactivation of DNA repair in breast cancer. Cancer Lett. 2014 Jan 28; 342(2):213-22. Nowsheen S, Aziz K, Tran PT, Gorgoulis VG, Yang ES, Georgakilas AG. PMID: 22634493.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    74. MARCKS regulates growth and radiation sensitivity and is a novel prognostic factor for glioma. Clin Cancer Res. 2012 Jun 01; 18(11):3030-41. Jarboe JS, Anderson JC, Duarte CW, Mehta T, Nowsheen S, Hicks PH, Whitley AC, Rohrbach TD, McCubrey RO, Chiu S, Burleson TM, Bonner JA, Gillespie GY, Yang ES, Willey CD. PMID: 22619307; PMCID: PMC3756473.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    75. Kinomic profiling approach identifies Trk as a novel radiation modulator. Radiother Oncol. 2012 Jun; 103(3):380-7. Jarboe JS, Jaboin JJ, Anderson JC, Nowsheen S, Stanley JA, Naji F, Ruijtenbeek R, Tu T, Hallahan DE, Yang ES, Bonner JA, Willey CD. PMID: 22561027; PMCID: PMC3368103.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    76. Targeting DNA damage and repair: embracing the pharmacological era for successful cancer therapy. Pharmacol Ther. 2012 Mar; 133(3):334-50. Aziz K, Nowsheen S, Pantelias G, Iliakis G, Gorgoulis VG, Georgakilas AG. PMID: 22197993.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    77. Molecular markers for cancer prognosis and treatment: have we struck gold? Cancer Lett. 2012 Dec 31; 327(1-2):142-52. Nowsheen S, Aziz K, Panayiotidis MI, Georgakilas AG. PMID: 22120674.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    78. Emerging roles of glycogen synthase kinase 3 in the treatment of brain tumors. Front Mol Neurosci. 2011; 4:47. Mills CN, Nowsheen S, Bonner JA, Yang ES. PMID: 22275880; PMCID: PMC3223722.
      View in: PubMed   Mentions: 29  
    79. Cetuximab augments cytotoxicity with poly (adp-ribose) polymerase inhibition in head and neck cancer. PLoS One. 2011; 6(8):e24148. Nowsheen S, Bonner JA, Lobuglio AF, Trummell H, Whitley AC, Dobelbower MC, Yang ES. PMID: 21912620; PMCID: PMC3166164.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    80. p53-dependent BRCA1 nuclear export controls cellular susceptibility to DNA damage. Cancer Res. 2011 Aug 15; 71(16):5546-57. Jiang J, Yang ES, Jiang G, Nowsheen S, Wang H, Wang T, Wang Y, Billheimer D, Chakravarthy AB, Brown M, Haffty B, Xia F. PMID: 21742769.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    81. The poly(ADP-Ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy. Radiother Oncol. 2011 Jun; 99(3):331-8. Nowsheen S, Bonner JA, Yang ES. PMID: 21719137; PMCID: PMC3157293.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    82. Inhibition of STAT-3 results in greater cetuximab sensitivity in head and neck squamous cell carcinoma. Radiother Oncol. 2011 Jun; 99(3):339-43. Bonner JA, Yang ES, Trummell HQ, Nowsheen S, Willey CD, Raisch KP. PMID: 21704410.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    83. Glycogen synthase kinase 3beta inhibition enhances repair of DNA double-strand breaks in irradiated hippocampal neurons. Neuro Oncol. 2011 May; 13(5):459-70. Yang ES, Nowsheen S, Wang T, Thotala DK, Xia F. PMID: 21398658; PMCID: PMC3093336.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    84. Nanotechnology in cancer therapy: targeting the inhibition of key DNA repair pathways. Curr Mol Med. 2010 Oct; 10(7):626-39. Aziz K, Nowsheen S, Georgakilas AG. PMID: 20712589.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    85. Tumors induce complex DNA damage in distant proliferative tissues in vivo. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):17992-7. Redon CE, Dickey JS, Nakamura AJ, Kareva IG, Naf D, Nowsheen S, Kryston TB, Bonner WM, Georgakilas AG, Sedelnikova OA. PMID: 20855610; PMCID: PMC2964229.
      View in: PubMed   Mentions: 59     Fields:    Translation:Animals
    86. DNA damage-induced cytotoxicity is dissociated from BRCA1's DNA repair function but is dependent on its cytosolic accumulation. Cancer Res. 2010 Aug 01; 70(15):6258-67. Wang H, Yang ES, Jiang J, Nowsheen S, Xia F. PMID: 20631074; PMCID: PMC2912952.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    87. Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice. J Clin Invest. 2009 May; 119(5):1124-35. Yang ES, Wang H, Jiang G, Nowsheen S, Fu A, Hallahan DE, Xia F. PMID: 19425167; PMCID: PMC2673855.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    88. Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues. Mutat Res. 2009 Mar 31; 674(1-2):131-6. Nowsheen S, Wukovich RL, Aziz K, Kalogerinis PT, Richardson CC, Panayiotidis MI, Bonner WM, Sedelnikova OA, Georgakilas AG. PMID: 18948225; PMCID: PMC6944316.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
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