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Sheila Crowe

Title(s)Professor In Residence, Medicine
SchoolHealth Sciences
Address9500 Gilman Drive #0063
La Jolla CA 92093
Phone858-534-2757
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    Collapse Biography 
    Collapse Education and Training
    Fellowship1988 McMaster University
    Residency1986McMaster University
    Internship1983McMaster University
    MD1982McMaster University
    BSc1979University of Toronto (Trinity College)

    Collapse Research 
    Collapse Research Activities and Funding
    Immunoprofiling for identifying biomarkers in celiac disease
    NIH/NIAID R21AI149636Feb 12, 2020 - Jan 31, 2022
    Role: Principal Investigator
    Food: At the Intersection of Gut Health and Disease (2019 James W. Freston Single Topic Conference)
    NIH/NIDDK R13DK122788Jul 1, 2019 - Jun 30, 2020
    Role: Principal Investigator
    AGA FORWARD PROGRAM - Fostering Opportunities Resulting in Workforce and Research Diversity
    NIH/NIDDK R25DK118761Jul 1, 2018 - Apr 30, 2023
    Role: Co-Principal Investigator
    OXIDATIVE INJURY TO GASTRIC EPITHELIAL CELLS BY H. PYLORI
    NIH/NIDDK R01DK061769Sep 15, 2009 - Jun 30, 2007
    Role: Principal Investigator
    1/2 SDSU/UCSD Cancer Center Comprehensive Partnership
    NIH/NCI U54CA132379Dec 1, 2007 - Sep 29, 2011
    Role: Principal Investigator
    2/2 SDSU/UCSD Cancer Center Comprehensive Partnership
    NIH/NCI U54CA132384Dec 1, 2007 - Sep 29, 2011
    Role: Principal Investigator
    GI Response to Injury: Canada 2004
    NIH/NIDDK R13DK070501Sep 25, 2004 - Aug 31, 2005
    Role: Principal Investigator
    GASTROINTESTINAL RESPONSE TO INJURY: CANADA 2001
    NIH/NIDDK R13DK061930Sep 30, 2001 - Sep 29, 2002
    Role: Principal Investigator
    Research Training in Digestive Diseases
    NIH/NIDDK T32DK007769Jul 1, 1999 - Jun 30, 2015
    Role: Principal Investigator
    Training Grant in Gastroenterology
    NIH/NIDDK T32DK007202Jul 1, 1976 - Mar 31, 1992
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The 2019 James W. Freston Conference: Food at the Intersection of Gut Health and Disease. Gastroenterology. 2020 Mar 26. Mullin G, Chey W, Crowe S. PMID: 32224128.
      View in: PubMed   Mentions:    Fields:    
    2. Putting celiac disease in perspective: Pathogenesis, comorbidity and transition of care. United European Gastroenterol J. 2020 Mar; 8(2):129-130. Crowe SE. PMID: 32213063.
      View in: PubMed   Mentions:
    3. Celiac Disease. Ann Intern Med. 2020 01 07; 172(1):ITC1-ITC16. Rubin JE, Crowe SE. PMID: 31905394.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    4. Educating the Next Generation of Undergraduate URM Cancer Scientists: Results and Lessons Learned from a Cancer Research Partnership Scholar Program. J Cancer Educ. 2019 Nov 14. Gaida E, Barrios AJ, Wolkowicz R, Crowe SE, Bernstein SI, Quintana Serrano MA, Dumbauld JN, Pakiz B, Cripps RM, Arredondo EM, Martinez ME, Madanat H. PMID: 31728922.
      View in: PubMed   Mentions:    Fields:    
    5. Safety and efficacy of AMG 714 in patients with type 2 refractory coeliac disease: a phase 2a, randomised, double-blind, placebo-controlled, parallel-group study. Lancet Gastroenterol Hepatol. 2019 12; 4(12):960-970. Cellier C, Bouma G, van Gils T, Khater S, Malamut G, Crespo L, Collin P, Green PHR, Crowe SE, Tsuji W, Butz E, Cerf-Bensussan N, Macintyre E, Parnes JR, Leon F, Hermine O, Mulder CJ. PMID: 31494097.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    6. Antigen-Specific Mucosal Immunity Regulates Development of Intestinal Bacteria-Mediated Diseases. Gastroenterology. 2019 12; 157(6):1530-1543.e4. Fujimoto K, Kawaguchi Y, Shimohigoshi M, Gotoh Y, Nakano Y, Usui Y, Hayashi T, Kimura Y, Uematsu M, Yamamoto T, Akeda Y, Rhee JH, Yuki Y, Ishii KJ, Crowe SE, Ernst PB, Kiyono H, Uematsu S. PMID: 31445037.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    7. Helicobacter pylori Infection. Reply. N Engl J Med. 2019 08 08; 381(6):588-589. Crowe SE. PMID: 31390513.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Helicobacter pylori Infection. N Engl J Med. 2019 Mar 21; 380(12):1158-1165. Crowe SE. PMID: 30893536.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. Food Allergy Vs Food Intolerance in Patients With Irritable Bowel Syndrome. Gastroenterol Hepatol (N Y). 2019 Jan; 15(1):38-40. Crowe SE. PMID: 30899207.
      View in: PubMed   Mentions:
    10. Statement on Best Practices in the Use of Pathology as a Diagnostic Tool for Celiac Disease: A Guide for Clinicians and Pathologists. Am J Surg Pathol. 2018 09; 42(9):e44-e58. Robert ME, Crowe SE, Burgart L, Yantiss RK, Lebwohl B, Greenson JK, Guandalini S, Murray JA. PMID: 29923907.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Houston Consensus Conference on Testing for Helicobacter pylori Infection in the United States. Clin Gastroenterol Hepatol. 2018 07; 16(7):992-1002.e6. El-Serag HB, Kao JY, Kanwal F, Gilger M, LoVecchio F, Moss SF, Crowe SE, Elfant A, Haas T, Hapke RJ, Graham DY. PMID: 29559361.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Vedolizumab in Patients With Common Variable Immune Deficiency and Gut Inflammation. Am J Gastroenterol. 2017 10; 112(10):1621. Boland BS, Riedl MA, Valasek MA, Crowe SE, Sandborn WJ. PMID: 28978958.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Society Leadership and Diversity: Hail to the Women! Gastroenterology. 2017 Sep; 153(3):618-620. Lok A, Burke CA, Crowe SE, Woods KL. PMID: 28821326.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Society Leadership and Diversity: Hail to the Women! Am J Gastroenterol. 2017 Sep; 112(9):1353-1355. Lok A, Burke CA, Crowe SE, Woods KL. PMID: 28809385.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Society Leadership and Diversity: Hail to the Women! Hepatology. 2017 09; 66(3):686-690. Lok A, Burke CA, Crowe SE, Woods KL. PMID: 28810060.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Society Leadership and Diversity: Hail to the Women! Gastrointest Endosc. 2017 Aug 02. Lok A, Burke CA, Crowe SE, Woods KL. PMID: 28821325.
      View in: PubMed   Mentions:    Fields:    
    17. Membrane-bound ß-catenin degradation is enhanced by ETS2-mediated Siah1 induction in Helicobacter pylori-infected gastric cancer cells. Oncogenesis. 2017 May 08; 6(5):e327. Das L, Kokate SB, Dixit P, Rath S, Rout N, Singh SP, Crowe SE, Bhattacharyya A. PMID: 28481365.
      View in: PubMed   Mentions:
    18. Oxidative Stress Resulting From Helicobacter pylori Infection Contributes to Gastric Carcinogenesis. Cell Mol Gastroenterol Hepatol. 2017 May; 3(3):316-322. Butcher LD, den Hartog G, Ernst PB, Crowe SE. PMID: 28462373.
      View in: PubMed   Mentions: 4     Fields:    
    19. Inhibition of histone/lysine acetyltransferase activity kills CoCl2-treated and hypoxia-exposed gastric cancer cells and reduces their invasiveness. Int J Biochem Cell Biol. 2017 01; 82:28-40. Rath S, Das L, Kokate SB, Ghosh N, Dixit P, Rout N, Singh SP, Chattopadhyay S, Ashktorab H, Smoot DT, Swamy MM, Kundu TK, Crowe SE, Bhattacharyya A. PMID: 27890795.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    20. Duodenal Bulb Biopsies Remain Relevant in the Diagnosis of Adult Celiac Disease. Clin Gastroenterol Hepatol. 2016 11; 14(11):1589-1592. Pace LA, Crowe SE. PMID: 27565522.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Development of Celiac Disease Therapeutics: Report of the Third Gastroenterology Regulatory Endpoints and Advancement of Therapeutics Workshop. Gastroenterology. 2016 09; 151(3):407-11. Leffler D, Kupfer SS, Lebwohl B, Bugin K, Griebel D, Lathrop JT, Lee JJ, Mulberg AE, Papadopoulos E, Tomaino J, Crowe SE. PMID: 27456385.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    22. Letter: global emergence of Helicobacter pylori antibiotic resistance - unanswered questions. Authors' reply. Aliment Pharmacol Ther. 2016 06; 43(11):1249-50. Thung I, Crowe SE, Valasek MA. PMID: 27137739.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    23. Complex Relationships Between Food, Diet, and the Microbiome. Gastroenterol Clin North Am. 2016 06; 45(2):253-65. Pace LA, Crowe SE. PMID: 27261897.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. Transition from childhood to adulthood in coeliac disease: the Prague consensus report. Gut. 2016 08; 65(8):1242-51. Ludvigsson JF, Agreus L, Ciacci C, Crowe SE, Geller MG, Green PH, Hill I, Hungin AP, Koletzko S, Koltai T, Lundin KE, Mearin ML, Murray JA, Reilly N, Walker MM, Sanders DS, Shamir R, Troncone R, Husby S. PMID: 27196596.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    25. ETS2 and Twist1 promote invasiveness of Helicobacter pylori-infected gastric cancer cells by inducing Siah2. Biochem J. 2016 06 01; 473(11):1629-40. Das L, Kokate SB, Rath S, Rout N, Singh SP, Crowe SE, Mukhopadhyay AK, Bhattacharyya A. PMID: 27048589.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    26. Regulation of Rac1 and Reactive Oxygen Species Production in Response to Infection of Gastrointestinal Epithelia. PLoS Pathog. 2016 Jan; 12(1):e1005382. den Hartog G, Chattopadhyay R, Ablack A, Hall EH, Butcher LD, Bhattacharyya A, Eckmann L, Harris PR, Das S, Ernst PB, Crowe SE. PMID: 26761793.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    27. Review article: the global emergence of Helicobacter pylori antibiotic resistance. Aliment Pharmacol Ther. 2016 Feb; 43(4):514-33. Thung I, Aramin H, Vavinskaya V, Gupta S, Park JY, Crowe SE, Valasek MA. PMID: 26694080.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    28. The role of C1q in recognition of apoptotic epithelial cells and inflammatory cytokine production by phagocytes during Helicobacter pylori infection. J Inflamm (Lond). 2015; 12:51. Fox S, Ryan KA, Berger AH, Petro K, Das S, Crowe SE, Ernst PB. PMID: 26357509.
      View in: PubMed   Mentions:
    29. The stomach in health and disease. Gut. 2015 Oct; 64(10):1650-68. Hunt RH, Camilleri M, Crowe SE, El-Omar EM, Fox JG, Kuipers EJ, Malfertheiner P, McColl KE, Pritchard DM, Rugge M, Sonnenberg A, Sugano K, Tack J. PMID: 26342014.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    30. Gluten Introduction, Breastfeeding, and Celiac Disease: Back to the Drawing Board. Am J Gastroenterol. 2016 Jan; 111(1):12-4. Lebwohl B, Murray JA, Verdú EF, Crowe SE, Dennis M, Fasano A, Green PH, Guandalini S, Khosla C. PMID: 26259710.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    31. Immunodeficiency and autoimmune enterocolopathy linked to NFAT5 haploinsufficiency. J Immunol. 2015 Mar 15; 194(6):2551-60. Boland BS, Widjaja CE, Banno A, Zhang B, Kim SH, Stoven S, Peterson MR, Jones MC, Su HI, Crowe SE, Bui JD, Ho SB, Okugawa Y, Goel A, Marietta EV, Khosroheidari M, Jepsen K, Aramburu J, López-Rodríguez C, Sandborn WJ, Murray JA, Harismendy O, Chang JT. PMID: 25667416.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    32. Food allergy and food intolerance. World Rev Nutr Diet. 2015; 111:76-81. Leung J, Crowe SE. PMID: 25418393.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Regulation of Noxa-mediated apoptosis in Helicobacter pylori-infected gastric epithelial cells. FASEB J. 2015 Mar; 29(3):796-806. Rath S, Das L, Kokate SB, Pratheek BM, Chattopadhyay S, Goswami C, Chattopadhyay R, Crowe SE, Bhattacharyya A. PMID: 25404713.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    34. Management of celiac disease: beyond the gluten-free diet. Gastroenterology. 2014 Jun; 146(7):1594-6. Crowe SE. PMID: 24786557.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases. Physiol Rev. 2014 Apr; 94(2):329-54. Bhattacharyya A, Chattopadhyay R, Mitra S, Crowe SE. PMID: 24692350.
      View in: PubMed   Mentions: 161     Fields:    Translation:HumansAnimalsCells
    36. Brain angiogenesis inhibitor 1 is expressed by gastric phagocytes during infection with Helicobacter pylori and mediates the recognition and engulfment of human apoptotic gastric epithelial cells. FASEB J. 2014 May; 28(5):2214-24. Das S, Sarkar A, Ryan KA, Fox S, Berger AH, Juncadella IJ, Bimczok D, Smythies LE, Harris PR, Ravichandran KS, Crowe SE, Smith PD, Ernst PB. PMID: 24509909.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    37. Apurinic/apyrimidinic endonuclease-1 is associated with angiogenesis and VEGF production via upregulation of COX-2 expression in esophageal cancer tissues. Am J Physiol Gastrointest Liver Physiol. 2014 Feb; 306(3):G183-90. Nagoya H, Futagami S, Shimpuku M, Tatsuguchi A, Wakabayashi T, Yamawaki H, Kodaka Y, Kawagoe T, Watarai Y, Makino H, Miyashita M, Tsuchiya S, Crowe SE, Sakamoto C. PMID: 24284961.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    38. Dietary proteins and functional gastrointestinal disorders. Am J Gastroenterol. 2013 May; 108(5):728-36. Boettcher E, Crowe SE. PMID: 23567359.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    39. Personal perspectives on mentoring. Gastroenterology. 2013 Mar; 144(3):488-91. Crowe SE. PMID: 23347674.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. Helicobacter pylori in gastric malignancies. Curr Gastroenterol Rep. 2012 Dec; 14(6):489-96. Bhandari A, Crowe SE. PMID: 23054813.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    41. Colonic diverticulosis is associated with an increased adenoma detection rate in patients undergoing first-time screening colonoscopy. J Interv Gastroenterol. 2012 Apr; 2(2):70-75. Gohil VB, Patrie JT, Shami VM, Sauer BG, Argo CK, Crowe SE, Wang AY. PMID: 23687589.
      View in: PubMed   Mentions:
    42. Environmental and lifestyle influences on disorders of the large and small intestine: implications for treatment. Dig Dis. 2011; 29(2):249-54. Hall EH, Crowe SE. PMID: 21734392.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    43. When to reconsider the diagnosis of irritable bowel syndrome. Gastroenterol Clin North Am. 2011 Jun; 40(2):291-307, vii. Hammerle CW, Crowe SE. PMID: 21601781.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    44. In the clinic. Celiac disease. Ann Intern Med. 2011 May 03; 154(9):ITC5-1-ITC5-15; quiz ITC5-16. Crowe SE. PMID: 21536935.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    45. Loss of TFF1 is associated with activation of NF-?B-mediated inflammation and gastric neoplasia in mice and humans. J Clin Invest. 2011 May; 121(5):1753-67. Soutto M, Belkhiri A, Piazuelo MB, Schneider BG, Peng D, Jiang A, Washington MK, Kokoye Y, Crowe SE, Zaika A, Correa P, Peek RM, El-Rifai W. PMID: 21490402.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    46. Mechanism of hypoxia-inducible factor 1 alpha-mediated Mcl1 regulation in Helicobacter pylori-infected human gastric epithelium. Am J Physiol Gastrointest Liver Physiol. 2010 Nov; 299(5):G1177-86. Bhattacharyya A, Chattopadhyay R, Hall EH, Mebrahtu ST, Ernst PB, Crowe SE. PMID: 20829524.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    47. A 41-year-old woman with abdominal complaints: is it food allergy or food intolerance? How to tell the difference. Clin Gastroenterol Hepatol. 2010 Sep; 8(9):755-9; quiz; e97. Degaetani MA, Crowe SE. PMID: 20363367.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. Helicobacter pylori-induced histone modification, associated gene expression in gastric epithelial cells, and its implication in pathogenesis. PLoS One. 2010 Apr 01; 5(4):e9875. Ding SZ, Fischer W, Kaparakis-Liaskos M, Liechti G, Merrell DS, Grant PA, Ferrero RL, Crowe SE, Haas R, Hatakeyama M, Goldberg JB. PMID: 20368982.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    49. Dual regulation by apurinic/apyrimidinic endonuclease-1 inhibits gastric epithelial cell apoptosis during Helicobacter pylori infection. Cancer Res. 2010 Apr 01; 70(7):2799-808. Chattopadhyay R, Bhattacharyya A, Crowe SE. PMID: 20332233.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    50. Treatment of postmenopausal osteoporosis in a patient with celiac disease. Nat Rev Endocrinol. 2010 Mar; 6(3):167-71. Pinkerton JV, Dalkin AC, Crowe SE, Wilson BB, Stelow EB. PMID: 20173778.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Acetylation of apurinic/apyrimidinic endonuclease-1 regulates Helicobacter pylori-mediated gastric epithelial cell apoptosis. Gastroenterology. 2009 Jun; 136(7):2258-69. Bhattacharyya A, Chattopadhyay R, Burnette BR, Cross JV, Mitra S, Ernst PB, Bhakat KK, Crowe SE. PMID: 19505426.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    52. Tumor necrosis factor (TNF)-alpha-induced IL-8 expression in gastric epithelial cells: role of reactive oxygen species and AP endonuclease-1/redox factor (Ref)-1. Cytokine. 2009 Jun; 46(3):359-69. O'Hara AM, Bhattacharyya A, Bai J, Mifflin RC, Ernst PB, Mitra S, Crowe SE. PMID: 19376732.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    53. A2A adenosine receptor (AR) activation inhibits pro-inflammatory cytokine production by human CD4+ helper T cells and regulates Helicobacter-induced gastritis and bacterial persistence. Mucosal Immunol. 2009 May; 2(3):232-42. Alam MS, Kurtz CC, Wilson JM, Burnette BR, Wiznerowicz EB, Ross WG, Rieger JM, Figler RA, Linden J, Crowe SE, Ernst PB. PMID: 19262506.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    54. CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice. J Infect Dis. 2009 Feb 15; 199(4):494-504. Alam MS, Kurtz CC, Rowlett RM, Reuter BK, Wiznerowicz E, Das S, Linden J, Crowe SE, Ernst PB. PMID: 19281303.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    55. Celecoxib inhibits apurinic/apyrimidinic endonuclease-1 expression and prevents gastric cancer in Helicobacter pylori-infected mongolian gerbils. Digestion. 2008; 78(2-3):93-102. Futagami S, Kawagoe T, Horie A, Shindo T, Hamamoto T, Suzuki K, Kusunoki M, Miyake K, Gudis K, Tsukui T, Crowe SE, Sakamoto C. PMID: 18987470.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    56. Expression of apurinic/apyrimidinic endonuclease-1 (APE-1) in H. pylori-associated gastritis, gastric adenoma, and gastric cancer. Helicobacter. 2008 Jun; 13(3):209-18. Futagami S, Hiratsuka T, Shindo T, Horie A, Hamamoto T, Suzuki K, Kusunoki M, Miyake K, Gudis K, Crowe SE, Tsukui T, Sakamoto C. PMID: 18466396.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    57. Celiac disease refractory to a gluten-free diet? Clin Chem. 2008 Feb; 54(2):441-4; discussion 444-5. Mikesh LM, Crowe SE, Bullock GC, Taylor NE, Bruns DE. PMID: 18223137.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    58. The effect of the cag pathogenicity island on binding of Helicobacter pylori to gastric epithelial cells and the subsequent induction of apoptosis. Helicobacter. 2007 Dec; 12(6):583-90. Minohara Y, Boyd DK, Hawkins HK, Ernst PB, Patel J, Crowe SE. PMID: 18001397.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    59. Helicobacter pylori infection and related gastrointestinal diseases. J Clin Gastroenterol. 2007 Jul; 41(6):548-58. Makola D, Peura DA, Crowe SE. PMID: 17577110.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    60. Helicobacter pylori infection induces oxidative stress and programmed cell death in human gastric epithelial cells. Infect Immun. 2007 Aug; 75(8):4030-9. Ding SZ, Minohara Y, Fan XJ, Wang J, Reyes VE, Patel J, Dirden-Kramer B, Boldogh I, Ernst PB, Crowe SE. PMID: 17562777.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    61. Detection of Celiac disease in primary care: a multicenter case-finding study in North America. Am J Gastroenterol. 2007 Jul; 102(7):1454-60. Catassi C, Kryszak D, Louis-Jacques O, Duerksen DR, Hill I, Crowe SE, Brown AR, Procaccini NJ, Wonderly BA, Hartley P, Moreci J, Bennett N, Horvath K, Burk M, Fasano A. PMID: 17355413.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansPHPublic Health
    62. Fatal encephalitis in a patient with refractory celiac disease presenting with myorhythmia and carpal spasm. Mov Disord. 2007 Feb 15; 22(3):407-11. Dimberg EL, Crowe SE, Trugman JM, Swerdlow RH, Lopes MB, Bourne TD, Burns TM. PMID: 17230474.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    63. Interleukin-8 induction by Helicobacter pylori in gastric epithelial cells is dependent on apurinic/apyrimidinic endonuclease-1/redox factor-1. J Immunol. 2006 Dec 01; 177(11):7990-9. O'Hara AM, Bhattacharyya A, Mifflin RC, Smith MF, Ryan KA, Scott KG, Naganuma M, Casola A, Izumi T, Mitra S, Ernst PB, Crowe SE. PMID: 17114472.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    64. The translation of Helicobacter pylori basic research to patient care. Gastroenterology. 2006 Jan; 130(1):188-206; quiz 212-3. Ernst PB, Peura DA, Crowe SE. PMID: 16401482.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    65. Expression of tight-junction protein claudin-7 is an early event in gastric tumorigenesis. Am J Pathol. 2005 Aug; 167(2):577-84. Johnson AH, Frierson HF, Zaika A, Powell SM, Roche J, Crowe S, Moskaluk CA, El-Rifai W. PMID: 16049341.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    66. Polarized expression of CD74 by gastric epithelial cells. J Histochem Cytochem. 2005 Dec; 53(12):1481-9. Barrera CA, Beswick EJ, Sierra JC, Bland D, Espejo R, Mifflin R, Adegboyega P, Crowe SE, Ernst PB, Reyes VE. PMID: 15923369.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    67. Gastrointestinal food allergy: new insights into pathophysiology and clinical perspectives. Gastroenterology. 2005 Apr; 128(4):1089-113. Bischoff S, Crowe SE. PMID: 15825090.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimals
    68. Helicobacter infection, chronic inflammation, and the development of malignancy. Curr Opin Gastroenterol. 2005 Jan; 21(1):32-8. Crowe SE. PMID: 15687882.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    69. Helicobacter pylori and H2O2 increase AP endonuclease-1/redox factor-1 expression in human gastric epithelial cells. Gastroenterology. 2004 Sep; 127(3):845-58. Ding SZ, O'Hara AM, Denning TL, Dirden-Kramer B, Mifflin RC, Reyes VE, Ryan KA, Elliott SN, Izumi T, Boldogh I, Mitra S, Ernst PB, Crowe SE. PMID: 15362040.
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    70. Food allergy and the gastrointestinal tract. Curr Opin Gastroenterol. 2004 Mar; 20(2):156-61. Bischoff S, Crowe SE. PMID: 15703638.
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    71. Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cells. J Biol Chem. 2003 Aug 29; 278(35):32552-60. Smith MF, Mitchell A, Li G, Ding S, Fitzmaurice AM, Ryan K, Crowe S, Goldberg JB. PMID: 12807870.
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    72. Oxidative stress induces the expression of Fas and Fas ligand and apoptosis in murine intestinal epithelial cells. Free Radic Biol Med. 2002 Dec 15; 33(12):1641-50. Denning TL, Takaishi H, Crowe SE, Boldogh I, Jevnikar A, Ernst PB. PMID: 12488132.
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    73. Interleukin-8 gene regulation in intestinal epithelial cells infected with rotavirus: role of viral-induced IkappaB kinase activation. Virology. 2002 Jun 20; 298(1):8-19. Casola A, Garofalo RP, Crawford SE, Estes MK, Mercurio F, Crowe SE, Brasier AR. PMID: 12093168.
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    74. Gastrointestinal food allergies: do they exist? Curr Gastroenterol Rep. 2001 Aug; 3(4):351-7. Crowe SE. PMID: 11470005.
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    75. Helicobacter pylori infection as a model for gastrointestinal immunity and chronic inflammatory diseases. Dig Dis. 2001; 19(2):104-11. Ernst PB, Takaishi H, Crowe SE. PMID: 11549818.
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    76. Prostaglandin levels in stimulated macrophages are controlled by phospholipase A2-activating protein and by activation of phospholipase C and D. J Biol Chem. 2001 Feb 23; 276(8):5467-75. Ribardo DA, Crowe SE, Kuhl KR, Peterson JW, Chopra AK. PMID: 11094054.
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    77. Virulence and pathogenicity of Helicobacter pylori. Gastroenterol Clin North Am. 2000 Sep; 29(3):649-70. Go MF, Crowe SE. PMID: 11030079.
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    78. Helicobacter pylori urease binds to class II MHC on gastric epithelial cells and induces their apoptosis. J Immunol. 2000 Aug 15; 165(4):1918-24. Fan X, Gunasena H, Cheng Z, Espejo R, Crowe SE, Ernst PB, Reyes VE. PMID: 10925273.
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    79. Neutrophil activation by bacterial lipoprotein versus lipopolysaccharide: differential requirements for serum and CD14. J Immunol. 2000 Mar 01; 164(5):2674-83. Soler-Rodriguez AM, Zhang H, Lichenstein HS, Qureshi N, Niesel DW, Crowe SE, Peterson JW, Klimpel GR. PMID: 10679108.
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    80. Myofibroblasts. II. Intestinal subepithelial myofibroblasts. Am J Physiol. 1999 08; 277(2):C183-201. Powell DW, Mifflin RC, Valentich JD, Crowe SE, Saada JI, West AB. PMID: 10444394.
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    81. Myofibroblasts. I. Paracrine cells important in health and disease. Am J Physiol. 1999 07; 277(1):C1-9. Powell DW, Mifflin RC, Valentich JD, Crowe SE, Saada JI, West AB. PMID: 10409103.
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    82. Regulation of the mucosal immune response. Am J Trop Med Hyg. 1999 Apr; 60(4 Suppl):2-9. Ernst PB, Song F, Klimpel GR, Haeberle H, Bamford KB, Crowe SE, Ye G, Reyes VE. PMID: 10344671.
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    83. Comparison of biopsy and serological methods of diagnosis of Helicobacter pylori infection and the potential role of antibiotics. Am J Gastroenterol. 1998 Aug; 93(8):1291-6. Luthra GK, DiNuzzo AR, Gourley WK, Crowe SE. PMID: 9707053.
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    84. Cell-specific expression of RANTES, MCP-1, and MIP-1alpha by lower airway epithelial cells and eosinophils infected with respiratory syncytial virus. J Virol. 1998 Jun; 72(6):4756-64. Olszewska-Pazdrak B, Casola A, Saito T, Alam R, Crowe SE, Mei F, Ogra PL, Garofalo RP. PMID: 9573240.
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    85. The effect of class II major histocompatibility complex expression on adherence of Helicobacter pylori and induction of apoptosis in gastric epithelial cells: a mechanism for T helper cell type 1-mediated damage. J Exp Med. 1998 May 18; 187(10):1659-69. Fan X, Crowe SE, Behar S, Gunasena H, Ye G, Haeberle H, Van Houten N, Gourley WK, Ernst PB, Reyes VE. PMID: 9584144.
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    86. Rotavirus infection of cultured intestinal epithelial cells induces secretion of CXC and CC chemokines. Gastroenterology. 1998 May; 114(5):947-55. Casola A, Estes MK, Crawford SE, Ogra PL, Ernst PB, Garofalo RP, Crowe SE. PMID: 9558283.
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    87. Lymphocytes in the human gastric mucosa during Helicobacter pylori have a T helper cell 1 phenotype. Gastroenterology. 1998 Mar; 114(3):482-92. Bamford KB, Fan X, Crowe SE, Leary JF, Gourley WK, Luthra GK, Brooks EG, Graham DY, Reyes VE, Ernst PB. PMID: 9496938.
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    88. How does Helicobacter pylori cause mucosal damage? The inflammatory response. Gastroenterology. 1997 Dec; 113(6 Suppl):S35-42; discussion S50. Ernst PB, Crowe SE, Reyes VE. PMID: 9394758.
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    89. Mast cell mediated ion transport in intestine from patients with and without inflammatory bowel disease. Gut. 1997 Dec; 41(6):785-92. Crowe SE, Luthra GK, Perdue MH. PMID: 9462211.
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    90. Differential stimulation of interleukin-12 (IL-12) and IL-10 by live and killed Helicobacter pylori in vitro and association of IL-12 production with gamma interferon-producing T cells in the human gastric mucosa. Infect Immun. 1997 Oct; 65(10):4229-35. Haeberle HA, Kubin M, Bamford KB, Garofalo R, Graham DY, El-Zaatari F, Karttunen R, Crowe SE, Reyes VE, Ernst PB. PMID: 9317031.
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    91. Expression of B7-1 and B7-2 costimulatory molecules by human gastric epithelial cells: potential role in CD4+ T cell activation during Helicobacter pylori infection. J Clin Invest. 1997 Apr 01; 99(7):1628-36. Ye G, Barrera C, Fan X, Gourley WK, Crowe SE, Ernst PB, Reyes VE. PMID: 9120006.
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    92. Expression of interleukin 8 and CD54 by human gastric epithelium after Helicobacter pylori infection in vitro. Gastroenterology. 1995 Jan; 108(1):65-74. Crowe SE, Alvarez L, Dytoc M, Hunt RH, Muller M, Sherman P, Patel J, Jin Y, Ernst PB. PMID: 7806065.
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    93. The role of the local immune response in the pathogenesis of peptic ulcer formation. Scand J Gastroenterol Suppl. 1994; 205:22-8. Ernst PB, Jin Y, Reyes VE, Crowe SE. PMID: 7863238.
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    94. Anti-immunoglobulin E-stimulated ion transport in human large and small intestine. Gastroenterology. 1993 Sep; 105(3):764-72. Crowe SE, Perdue MH. PMID: 8359647.
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    95. Gastrointestinal food hypersensitivity: basic mechanisms of pathophysiology. Gastroenterology. 1992 Sep; 103(3):1075-95. Crowe SE, Perdue MH. PMID: 1499910.
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    96. Allergic reactions of rat jejunal mucosa. Ion transport responses to luminal antigen and inflammatory mediators. Gastroenterology. 1990 Jul; 99(1):74-82. Crowe SE, Sestini P, Perdue MH. PMID: 2344944.
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