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Shaun Mckinnie

Title(s)Postdoctoral Scholar, Center for Marine Biotechnology and Biomedecine
SchoolMarine Sciences
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Rothe ML, Li J, Garibay E, Moore BS, McKinnie SMK. Synthesis, bioactivity, and enzymatic modification of antibacterial thiotetromycin derivatives. Org Biomol Chem. 2019 Mar 14. PMID: 30869693.
      View in: PubMed
    2. Fischer C, Lamer T, Wang W, McKinnie SMK, Iturrioz X, Llorens-Cortes C, Oudit GY, Vederas JC. Plasma kallikrein cleaves and inactivates apelin-17: Palmitoyl- and PEG-extended apelin-17 analogs as metabolically stable blood pressure-lowering agents. Eur J Med Chem. 2019 Jan 18; 166:119-124. PMID: 30690406.
      View in: PubMed
    3. McKinnie S, Miles ZD, Jordan PA, Awakawa T, Pepper HP, Murray LAM, George JH, Moore BS. Total enzyme syntheses of napyradiomycins A1 and B1. J Am Chem Soc. 2018 Dec 10. PMID: 30525563.
      View in: PubMed
    4. Brunson JK, McKinnie SMK, Chekan JR, McCrow JP, Miles ZD, Bertrand EM, Bielinski VA, Luhavaya H, Oborník M, Smith GJ, Hutchins DA, Allen AE, Moore BS. Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom. Science. 2018 09 28; 361(6409):1356-1358. PMID: 30262498.
      View in: PubMed
    5. Murray LAM, McKinnie SMK, Pepper HP, Erni R, Miles ZD, Cruickshank MC, López-Pérez B, Moore BS, George JH. Total Synthesis Establishes the Biosynthetic Pathway to the Naphterpin and Marinone Natural Products. Angew Chem Int Ed Engl. 2018 Aug 20; 57(34):11009-11014. PMID: 29935040.
      View in: PubMed
    6. Zheng J, McKinnie SMK, El Gamal A, Feng W, Dong Y, Agarwal V, Fenical W, Kumar A, Cao Z, Moore BS, Pessah IN. Correction to Organohalogens Naturally Biosynthesized in Marine Environments and Produced As Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol. 2018 Jul 03; 52(13):7594. PMID: 29916692.
      View in: PubMed
    7. Zheng J, McKinnie SMK, El Gamal A, Feng W, Dong Y, Agarwal V, Fenical W, Kumar A, Cao Z, Moore BS, Pessah IN. Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol. 2018 May 01; 52(9):5469-5478. PMID: 29617551.
      View in: PubMed
    8. McKinnie SMK, Miles ZD, Moore BS. Characterization and Biochemical Assays of Streptomyces Vanadium-Dependent Chloroperoxidases. Methods Enzymol. 2018; 604:405-424. PMID: 29779661.
      View in: PubMed
    9. McKinnie SMK, Wang W, Fischer C, McDonald T, Kalin KR, Iturrioz X, Llorens-Cortes C, Oudit GY, Vederas JC. Synthetic Modification within the "RPRL" Region of Apelin Peptides: Impact on Cardiovascular Activity and Stability to Neprilysin and Plasma Degradation. J Med Chem. 2017 07 27; 60(14):6408-6427. PMID: 28685579.
      View in: PubMed
    10. Zhong JC, Zhang ZZ, Wang W, McKinnie SMK, Vederas JC, Oudit GY. Targeting the apelin pathway as a novel therapeutic approach for cardiovascular diseases. Biochim Biophys Acta Mol Basis Dis. 2017 08; 1863(8):1942-1950. PMID: 27825851.
      View in: PubMed
    11. McKinnie SM, Fischer C, Tran KM, Wang W, Mosquera F, Oudit GY, Vederas JC. The Metalloprotease Neprilysin Degrades and Inactivates Apelin Peptides. Chembiochem. 2016 08 17; 17(16):1495-8. PMID: 27377680.
      View in: PubMed
    12. Wang W, McKinnie SM, Farhan M, Paul M, McDonald T, McLean B, Llorens-Cortes C, Hazra S, Murray AG, Vederas JC, Oudit GY. Angiotensin-Converting Enzyme 2 Metabolizes and Partially Inactivates Pyr-Apelin-13 and Apelin-17: Physiological Effects in the Cardiovascular System. Hypertension. 2016 08; 68(2):365-77. PMID: 27217402.
      View in: PubMed
    13. McKinnie SM, Rodriguez-Lopez EM, Vederas JC, Crowther JM, Suzuki H, Dobson RC, Leustek T, Triassi AJ, Wheatley MS, Hudson AO. Differential response of orthologous L,L-diaminopimelate aminotransferases (DapL) to enzyme inhibitory antibiotic lead compounds. Bioorg Med Chem. 2014 Jan 01; 22(1):523-30. PMID: 24268540.
      View in: PubMed
    14. Wang W, McKinnie SM, Patel VB, Haddad G, Wang Z, Zhabyeyev P, Das SK, Basu R, McLean B, Kandalam V, Penninger JM, Kassiri Z, Vederas JC, Murray AG, Oudit GY. Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues. J Am Heart Assoc. 2013 Jul 01; 2(4):e000249. PMID: 23817469; PMCID: PMC3828798.
    15. Ross AC, McKinnie SM, Vederas JC. The synthesis of active and stable diaminopimelate analogues of the lantibiotic peptide lactocin S. J Am Chem Soc. 2012 Feb 01; 134(4):2008-11. PMID: 22280450.
      View in: PubMed
    16. Pattabiraman VR, McKinnie SM, Vederas JC. Solid-supported synthesis and biological evaluation of the lantibiotic peptide bis(desmethyl) lacticin 3147 A2. Angew Chem Int Ed Engl. 2008; 47(49):9472-5. PMID: 18937239.
      View in: PubMed