Shashi Tiwari

Title(s)Assistant Project Scientist, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    1. Evaluation of Microchip-Based Point-Of-Care Device "Gazelle" for Diagnosis of Sickle Cell Disease in India. Front Med (Lausanne). 2021; 8:639208. Shrivas S, Patel M, Kumar R, Gwal A, Uikey R, Tiwari SK, Verma AK, Thota P, Das A, Bharti PK, Shanmugam R. PMID: 34722554; PMCID: PMC8548372.
      View in: PubMed   Mentions: 3  
    2. Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors. J Med Chem. 2022 02 24; 65(4):2866-2879. Huff S, Kummetha IR, Tiwari SK, Huante MB, Clark AE, Wang S, Bray W, Smith D, Carlin AF, Endsley M, Rana TM. PMID: 34570513; PMCID: PMC8491550.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    3. First Observation of Compound Heterozygosity for Hb S/Hb Lepore-Hollandia in India. Indian J Hematol Blood Transfus. 2022 Jan; 38(1):187-190. Mun A, Kumar R, Tiwari S, Uikey R, Thakur P, Mishra S, Chakma T, Shanmugam R. PMID: 34334973; PMCID: PMC8315253.
      View in: PubMed   Mentions:
    4. Therapeutic efficacy of artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in four malaria endemic states of India. Malar J. 2021 May 21; 20(1):229. Krishna S, Mishra S, Tiwari P, Vishwakarma AK, Khandai S, Shrivastava S, Verma AK, Tiwari S, Barman H, Jhariya S, Tiwari P, Tidgam AS, Varun BM, Singh S, Yerane N, Tembhurne CR, Mandavi PL, Tekam SS, Malik M, Behera KP, Jayswar H, Sonwani K, Diggikar MS, Pradhan MM, Khasotiya SS, Kumar A, Dhingra N, Bustos MDG, Christophel EM, Ringwald P, Kumari R, Shukla MM, Singh N, Das A, Bharti PK. PMID: 34020652; PMCID: PMC8139028.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsPHPublic Health
    5. Revealing Tissue-Specific SARS-CoV-2 Infection and Host Responses using Human Stem Cell-Derived Lung and Cerebral Organoids. Stem Cell Reports. 2021 03 09; 16(3):437-445. Tiwari SK, Wang S, Smith D, Carlin AF, Rana TM. PMID: 33631122; PMCID: PMC7879814.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    6. Rapid 3D Bioprinting of Glioblastoma Model Mimicking Native Biophysical Heterogeneity. Small. 2021 04; 17(15):e2006050. Tang M, Tiwari SK, Agrawal K, Tan M, Dang J, Tam T, Tian J, Wan X, Schimelman J, You S, Xia Q, Rana TM, Chen S. PMID: 33502104; PMCID: PMC8049977.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    7. m6A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells. ACS Chem Biol. 2021 02 19; 16(2):324-333. Huff S, Tiwari SK, Gonzalez GM, Wang Y, Rana TM. PMID: 33412003; PMCID: PMC7901021.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    8. In-silico primer designing and PCR for detection of novel coronavirus-19. J Infect Public Health. 2020 Dec; 13(12):1885-1886. Tiwari SK, Singh AK, Singh A. PMID: 33158805; PMCID: PMC7584436.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    9. Zika virus depletes neural stem cells and evades selective autophagy by suppressing the Fanconi anemia protein FANCC. EMBO Rep. 2020 12 03; 21(12):e49183. Tiwari SK, Dang JW, Lin N, Qin Y, Wang S, Rana TM. PMID: 33073500; PMCID: PMC7726779.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    10. Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and other coronaviruses by depleting membrane cholesterol. EMBO J. 2020 11 02; 39(21):e106057. Wang S, Li W, Hui H, Tiwari SK, Zhang Q, Croker BA, Rawlings S, Smith D, Carlin AF, Rana TM. PMID: 32944968; PMCID: PMC7537045.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    11. Cypermethrin Impairs Hippocampal Neurogenesis and Cognitive Functions by Altering Neural Fate Decisions in the Rat Brain. Mol Neurobiol. 2021 Jan; 58(1):263-280. Yadav A, Tandon A, Seth B, Goyal S, Singh SJ, Tiwari SK, Agarwal S, Nair S, Chaturvedi RK. PMID: 32920670.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    12. Correction: Dynamin-related protein 1 inhibition mitigates bisphenol A-mediated alterations in mitochondrial dynamics and neural stem cell proliferation and differentiation. J Biol Chem. 2020 Feb 28; 295(9):2887. Agarwal S, Yadav A, Tiwari SK, Seth B, Chauhan LKS, Khare P, Ray RS, Chaturvedi RK. PMID: 32111722; PMCID: PMC7049950.
      View in: PubMed   Mentions:    Fields:    
    13. Withdrawal: Activation of autophagic flux against xenoestrogen bisphenol-A-Induced hippocampal neurodegeneration via AMP kinase (AMPK)/mammalian target of rapamycin (mTOR) pathways. J Biol Chem. 2020 02 28; 295(9):2889. Agarwal S, Tiwari SK, Seth B, Yadav A, Singh A, Mudawal A, Chauhan LKS, Gupta SK, Choubey V, Tripathi A, Kumar A, Ray RS, Shukla S, Parmar D, Chaturvedi RK. PMID: 32111724; PMCID: PMC7049953.
      View in: PubMed   Mentions:    Fields:    
    14. Glial cell diversity and methamphetamine-induced neuroinflammation in human cerebral organoids. Mol Psychiatry. 2021 04; 26(4):1194-1207. Dang J, Tiwari SK, Agrawal K, Hui H, Qin Y, Rana TM. PMID: 32051547; PMCID: PMC7423603.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    15. Integrin αvβ5 Internalizes Zika Virus during Neural Stem Cells Infection and Provides a Promising Target for Antiviral Therapy. Cell Rep. 2020 01 28; 30(4):969-983.e4. Wang S, Zhang Q, Tiwari SK, Lichinchi G, Yau EH, Hui H, Li W, Furnari F, Rana TM. PMID: 31956073; PMCID: PMC7293422.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    16. Correction to: Neuroprotective Role of Novel Triazine Derivatives by Activating Wnt/β Catenin Signaling Pathway in Rodent Models of Alzheimer's Disease. Mol Neurobiol. 2019 Oct; 56(10):7246-7248. Sinha A, Tamboli RS, Seth B, Kanhed AM, Tiwari SK, Agarwal S, Nair S, Giridhar R, Chaturvedi RK, Yadav MR. PMID: 31463875.
      View in: PubMed   Mentions:    Fields:    
    17. The Long Noncoding RNA HEAL Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter. mBio. 2019 09 24; 10(5). Chao TC, Zhang Q, Li Z, Tiwari SK, Qin Y, Yau E, Sanchez A, Singh G, Chang K, Kaul M, Karris MAY, Rana TM. PMID: 31551335; PMCID: PMC6759764.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    18. Correction to: Inhibitory Effects of Bisphenol-A on Neural Stem Cells Proliferation and Differentiation in the Rat Brain Are Dependent on Wnt/β-Catenin Pathway. Mol Neurobiol. 2019 Sep; 56(9):6666-6667. Tiwari SK, Agarwal S, Seth B, Yadav A, Ray RS, Mishra VN, Chaturvedi RK. PMID: 31273605.
      View in: PubMed   Mentions:    Fields:    
    19. Correction to: Bisphenol-A Mediated Inhibition of Hippocampal Neurogenesis Attenuated by Curcumin via Canonical Wnt Pathway. Mol Neurobiol. 2019 Sep; 56(9):6660-6662. Tiwari SK, Agarwal S, Tripathi A, Chaturvedi RK. PMID: 31254153.
      View in: PubMed   Mentions: 1     Fields:    
    20. Correction to: Bisphenol-A Impairs Myelination Potential During Development in the Hippocampus of the Rat Brain. Mol Neurobiol. 2019 Jul; 56(7):5270-5271. Tiwari SK, Agarwal S, Chauhan LKS, Mishra VN, Chaturvedi RK. PMID: 31054077.
      View in: PubMed   Mentions: 3     Fields:    
    21. Genome-wide Integrative Analysis of Zika-Virus-Infected Neuronal Stem Cells Reveals Roles for MicroRNAs in Cell Cycle and Stemness. Cell Rep. 2019 06 18; 27(12):3618-3628.e5. Dang JW, Tiwari SK, Qin Y, Rana TM. PMID: 31216479; PMCID: PMC6687627.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    22. Correction to Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer's Disease Model via Canonical Wnt/β-Catenin Pathway. ACS Nano. 2019 Jun 25; 13(6):7355. Tiwari SK, Agarwal S, Seth B, Yadav A, Nair S, Bhatnagar P, Karmakar M, Kumari M, Chauhan LKS, Patel DK, Srivastava V, Singh D, Gupta SK, Tripathi A, Chaturvedi RK, Gupta KC. PMID: 31135130.
      View in: PubMed   Mentions: 3     Fields:    
    23. The long noncoding RNA ROCKI regulates inflammatory gene expression. EMBO J. 2019 04 15; 38(8). Zhang Q, Chao TC, Patil VS, Qin Y, Tiwari SK, Chiou J, Dobin A, Tsai CM, Li Z, Dang J, Gupta S, Urdahl K, Nizet V, Gingeras TR, Gaulton KJ, Rana TM. PMID: 30918008; PMCID: PMC6463213.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    24. ERRATUM Mechanism of Nanotization-Mediated Improvement in the Efficacy of Caffeine Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Parkinsonism (Journal of Biomedical Nanotechnology, Vol. 11(12), pp. 2211-2222 (2015)). J Biomed Nanotechnol. 2019 01 01; 15(1):212-213. Singhal NK, Agarwal S, Bhatnagar P, Tiwari MN, Tiwari SK, Srivastava G, Kumar P, Seth B, Patel DK, Chaturvedi RK, Singh MP, Gupta KC. PMID: 30480528.
      View in: PubMed   Mentions:    Fields:    
    25. Hexadecylated linear PEI self-assembled nanostructures as efficient vectors for neuronal gene delivery. Drug Deliv Transl Res. 2018 10; 8(5):1436-1449. Bansal R, Seth B, Tiwari S, Jahan S, Kumari M, Pant AB, Chaturvedi RK, Kumar P, Gupta KC. PMID: 29671276.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    26. Inhibition of the transforming growth factor-β/SMAD cascade mitigates the anti-neurogenic effects of the carbamate pesticide carbofuran. J Biol Chem. 2017 11 24; 292(47):19423-19440. Seth B, Yadav A, Agarwal S, Tiwari SK, Chaturvedi RK. PMID: 28982980; PMCID: PMC5702680.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    27. Zika virus infection reprograms global transcription of host cells to allow sustained infection. Emerg Microbes Infect. 2017 Apr 26; 6(4):e24. Tiwari SK, Dang J, Qin Y, Lichinchi G, Bansal V, Rana TM. PMID: 28442752; PMCID: PMC5457678.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    28. Dynamin-related Protein 1 Inhibition Mitigates Bisphenol A-mediated Alterations in Mitochondrial Dynamics and Neural Stem Cell Proliferation and Differentiation. J Biol Chem. 2016 07 29; 291(31):15923-39. Agarwal S, Yadav A, Tiwari SK, Seth B, Chauhan LK, Khare P, Ray RS, Chaturvedi RK. PMID: 27252377; PMCID: PMC4965546.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    29. Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3. Cell Stem Cell. 2016 08 04; 19(2):258-265. Dang J, Tiwari SK, Lichinchi G, Qin Y, Patil VS, Eroshkin AM, Rana TM. PMID: 27162029; PMCID: PMC5116380.
      View in: PubMed   Mentions: 346     Fields:    Translation:HumansAnimalsCells
    30. Photoprotective efficiency of PLGA-curcumin nanoparticles versus curcumin through the involvement of ERK/AKT pathway under ambient UV-R exposure in HaCaT cell line. Biomaterials. 2016 Apr; 84:25-41. Chopra D, Ray L, Dwivedi A, Tiwari SK, Singh J, Singh KP, Kushwaha HN, Jahan S, Pandey A, Gupta SK, Chaturvedi RK, Pant AB, Ray RS, Gupta KC. PMID: 26803409.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    31. Human Mesenchymal Stem Cell-Derived Conditioned Media for Hair Regeneration Applications. J Stem Cells. 2016; 11(4):201-211. Ramdasi S, Tiwari SK. PMID: 28296872.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    32. Mechanism of Nanotization-Mediated Improvement in the Efficacy of Caffeine Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Parkinsonism. J Biomed Nanotechnol. 2015 Dec; 11(12):2211-22. Singhal NK, Agarwal S, Bhatnagar P, Tiwari MN, Tiwari SK, Srivastava G, Kumar P, Brashket S, Patel DK, Chaturvedi RK, Singh MP, Gupta KC. PMID: 26510314.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    33. Ethosuximide Induces Hippocampal Neurogenesis and Reverses Cognitive Deficits in an Amyloid-β Toxin-induced Alzheimer Rat Model via the Phosphatidylinositol 3-Kinase (PI3K)/Akt/Wnt/β-Catenin Pathway. J Biol Chem. 2015 Nov 20; 290(47):28540-28558. Tiwari SK, Seth B, Agarwal S, Yadav A, Karmakar M, Gupta SK, Choubey V, Sharma A, Chaturvedi RK. PMID: 26420483; PMCID: PMC4653709.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
    34. Activation of Autophagic Flux against Xenoestrogen Bisphenol-A-induced Hippocampal Neurodegeneration via AMP kinase (AMPK)/Mammalian Target of Rapamycin (mTOR) Pathways. J Biol Chem. 2015 Aug 21; 290(34):21163-21184. Agarwal S, Tiwari SK, Seth B, Yadav A, Singh A, Mudawal A, Chauhan LKS, Gupta SK, Choubey V, Tripathi A, Kumar A, Ray RS, Shukla S, Parmar D, Chaturvedi RK. PMID: 26139607; PMCID: PMC4543672.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    35. Bisphenol-A Mediated Inhibition of Hippocampal Neurogenesis Attenuated by Curcumin via Canonical Wnt Pathway. Mol Neurobiol. 2016 07; 53(5):3010-3029. Tiwari SK, Agarwal S, Tripathi A, Chaturvedi RK. PMID: 25963729.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    36. Inhibitory Effects of Bisphenol-A on Neural Stem Cells Proliferation and Differentiation in the Rat Brain Are Dependent on Wnt/β-Catenin Pathway. Mol Neurobiol. 2015 Dec; 52(3):1735-1757. Tiwari SK, Agarwal S, Seth B, Yadav A, Ray RS, Mishra VN, Chaturvedi RK. PMID: 25381574.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    37. Neuroprotective Role of Novel Triazine Derivatives by Activating Wnt/β Catenin Signaling Pathway in Rodent Models of Alzheimer's Disease. Mol Neurobiol. 2015 Aug; 52(1):638-52. Sinha A, Tamboli RS, Seth B, Kanhed AM, Tiwari SK, Agarwal S, Nair S, Giridhar R, Chaturvedi RK, Yadav MR. PMID: 25257697.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    38. Bisphenol-A impairs myelination potential during development in the hippocampus of the rat brain. Mol Neurobiol. 2015; 51(3):1395-416. Tiwari SK, Agarwal S, Chauhan LK, Mishra VN, Chaturvedi RK. PMID: 25084756.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    39. Association between children death and consumption of Cassia occidentalis seeds: clinical and experimental investigations. Food Chem Toxicol. 2014 May; 67:236-48. Panigrahi G, Tiwari S, Ansari KM, Chaturvedi RK, Khanna VK, Chaudhari BP, Vashistha VM, Raisuddin S, Das M. PMID: 24614135.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    40. Mitochondria: prospective targets for neuroprotection in Parkinson's disease. Curr Pharm Des. 2014; 20(35):5558-73. Yadav A, Agarwal S, Tiwari SK, Chaturvedi RK. PMID: 24606805.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    41. Peptide therapeutics in neurodegenerative disorders. Curr Med Chem. 2014; 21(23):2610-31. Tiwari SK, Chaturvedi RK. PMID: 24533803.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    42. Curcumin-loaded nanoparticles potently induce adult neurogenesis and reverse cognitive deficits in Alzheimer's disease model via canonical Wnt/β-catenin pathway. ACS Nano. 2014 Jan 28; 8(1):76-103. Tiwari SK, Agarwal S, Seth B, Yadav A, Nair S, Bhatnagar P, Karmakar M, Kumari M, Chauhan LK, Patel DK, Srivastava V, Singh D, Gupta SK, Tripathi A, Chaturvedi RK, Gupta KC. PMID: 24467380.
      View in: PubMed   Mentions: 155     Fields:    Translation:Animals
    43. Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism. Free Radic Biol Med. 2013 Dec; 65:704-718. Tiwari MN, Agarwal S, Bhatnagar P, Singhal NK, Tiwari SK, Kumar P, Chauhan LKS, Patel DK, Chaturvedi RK, Singh MP, Gupta KC. PMID: 23933227.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    44. Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease. Hum Mol Genet. 2012 Aug 01; 21(15):3474-88. Chaturvedi RK, Hennessey T, Johri A, Tiwari SK, Mishra D, Agarwal S, Kim YS, Beal MF. PMID: 22589249; PMCID: PMC3491961.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    45. Prenatal carbofuran exposure inhibits hippocampal neurogenesis and causes learning and memory deficits in offspring. Toxicol Sci. 2012 May; 127(1):84-100. Mishra D, Tiwari SK, Agarwal S, Sharma VP, Chaturvedi RK. PMID: 22240977.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCellsPHPublic Health
    46. Functionalized chiral vinyl aminosulfoxonium salts: asymmetric synthesis and application to the synthesis of enantiopure unsaturated prolines, beta,gamma-dehydro amino acids, and cyclopentanoid keto aminosulfoxonium ylides. J Am Chem Soc. 2006 Jun 07; 128(22):7360-73. Tiwari SK, Gais HJ, Lindenmaier A, Babu GS, Raabe G, Reddy LR, Köhler F, Günter M, Koep S, Iska VB. PMID: 16734492.
      View in: PubMed   Mentions: 3     Fields:    
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