Samuel Klein

TitleAdjunct Professor
InstitutionUniversity of California San Diego
Address9500 Gilman Drive #0956
La Jolla CA 92093
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    1. van Vliet S, Smith GI, Porter L, Ramaswamy R, Reeds DN, Okunade AL, Yoshino J, Klein S, Mittendorfer B. The muscle anabolic effect of protein ingestion during a hyperinsulinemic euglycemic clamp in middle-aged women is not caused by leucine alone. J Physiol. 2018 Jul 27. PMID: 30054913.
      View in: PubMed
    2. Smith GI, Commean PK, Reeds DN, Klein S, Mittendorfer B. Effect of Protein Supplementation During Diet-Induced Weight Loss on Muscle Mass and Strength: A Randomized Controlled Study. Obesity (Silver Spring). 2018 May; 26(5):854-861. PMID: 29687650.
      View in: PubMed
    3. Pettus J, Reeds D, Cavaiola TS, Boeder S, Levin M, Tobin G, Cava E, Thai D, Shi J, Yan H, Bautista E, McMillan J, Unger R, Henry RR, Klein S. Effect of a glucagon receptor antibody (REMD-477) in type 1 diabetes: A randomized controlled trial. Diabetes Obes Metab. 2018 May; 20(5):1302-1305. PMID: 29283470.
      View in: PubMed
    4. Reeds DN, Pietka TA, Yarasheski KE, Cade WT, Patterson BW, Okunade A, Abumrad NA, Klein S. HIV infection does not prevent the metabolic benefits of diet-induced weight loss in women with obesity. Obesity (Silver Spring). 2017 Apr; 25(4):682-688. PMID: 28245099.
      View in: PubMed
    5. Smith GI, Yoshino J, Kelly SC, Reeds DN, Okunade A, Patterson BW, Klein S, Mittendorfer B. High-Protein Intake during Weight Loss Therapy Eliminates the Weight-Loss-Induced Improvement in Insulin Action in Obese Postmenopausal Women. Cell Rep. 2016 10 11; 17(3):849-861. PMID: 27732859.
      View in: PubMed
    6. Weiss EP, Albert SG, Reeds DN, Kress KS, McDaniel JL, Klein S, Villareal DT. Effects of matched weight loss from calorie restriction, exercise, or both on cardiovascular disease risk factors: a randomized intervention trial. Am J Clin Nutr. 2016 Sep; 104(3):576-86. PMID: 27465384; PMCID: PMC4997297 [Available on 09/01/17].
    7. Petry TZ, Fabbrini E, Otoch JP, Carmona MA, Caravatto PP, Salles JE, Sarian T, Correa JL, Schiavon CA, Patterson BW, Cohen R, Klein S. Effect of Duodenal-Jejunal Bypass Surgery on Glycemic Control in Type 2 Diabetes: A Randomized Controlled Trial. Obesity (Silver Spring). 2015 Oct; 23(10):1973-9. PMID: 26414562; PMCID: PMC4603288 [Available on 10/01/16].
    8. Smith GI, Julliand S, Reeds DN, Sinacore DR, Klein S, Mittendorfer B. Fish oil-derived n-3 PUFA therapy increases muscle mass and function in healthy older adults. Am J Clin Nutr. 2015 Jul; 102(1):115-22. PMID: 25994567; PMCID: PMC4480667.
    9. Weiss EP, Albert SG, Reeds DN, Kress KS, Ezekiel UR, McDaniel JL, Patterson BW, Klein S, Villareal DT. Calorie Restriction and Matched Weight Loss From Exercise: Independent and Additive Effects on Glucoregulation and the Incretin System in Overweight Women and Men. Diabetes Care. 2015 Jul; 38(7):1253-62. PMID: 25877812; PMCID: PMC4477336.
    10. Smith GI, Yoshino J, Stromsdorfer KL, Klein SJ, Magkos F, Reeds DN, Klein S, Mittendorfer B. Protein Ingestion Induces Muscle Insulin Resistance Independent of Leucine-Mediated mTOR Activation. Diabetes. 2015 May; 64(5):1555-63. PMID: 25475435; PMCID: PMC4407849.
    11. Reeds DN, Mohammed BS, Klein S, Boswell CB, Young VL. Metabolic and structural effects of phosphatidylcholine and deoxycholate injections on subcutaneous fat: a randomized, controlled trial. Aesthet Surg J. 2013 Mar; 33(3):400-8. PMID: 23439063; PMCID: PMC3667691.
    12. Wang X, Belani S, Coyne DW, Fabbrini E, Reeds DN, Patterson BW, Mittendorfer B, Klein S. Very Low Density Lipoprotein Metabolism in Patients with Chronic Kidney Disease. Cardiorenal Med. 2012 Feb; 2(1):57-65. PMID: 22493604.
      View in: PubMed
    13. Reeds DN, Patterson BW, Okunade A, Holloszy JO, Polonsky KS, Klein S. Ginseng and ginsenoside Re do not improve ß-cell function or insulin sensitivity in overweight and obese subjects with impaired glucose tolerance or diabetes. Diabetes Care. 2011 May; 34(5):1071-6. PMID: 21411505; PMCID: PMC3114517.
    14. Kirk E, Reeds DN, Finck BN, Mayurranjan SM, Mayurranjan MS, Patterson BW, Klein S. Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction. Gastroenterology. 2009 May; 136(5):1552-60. PMID: 19208352; PMCID: PMC2677125.
    15. Mohammed BS, Cohen S, Reeds D, Young VL, Klein S. Long-term effects of large-volume liposuction on metabolic risk factors for coronary heart disease. Obesity (Silver Spring). 2008 Dec; 16(12):2648-51. PMID: 18820648; PMCID: PMC2656416.
    16. Reeds DN, Stuart CA, Perez O, Klein S. Adipose tissue, hepatic, and skeletal muscle insulin sensitivity in extremely obese subjects with acanthosis nigricans. Metabolism. 2006 Dec; 55(12):1658-63. PMID: 17142140.
      View in: PubMed
    17. Cade WT, Reeds DN, Mittendorfer B, Patterson BW, Powderly WG, Klein S, Yarasheski KE. Blunted lipolysis and fatty acid oxidation during moderate exercise in HIV-infected subjects taking HAART. Am J Physiol Endocrinol Metab. 2007 Mar; 292(3):E812-9. PMID: 17106066; PMCID: PMC3935339.
    18. Reeds DN, Cade WT, Patterson BW, Powderly WG, Klein S, Yarasheski KE. Whole-body proteolysis rate is elevated in HIV-associated insulin resistance. Diabetes. 2006 Oct; 55(10):2849-55. PMID: 17003352; PMCID: PMC1764855.
    19. Chaparro J, Reeds DN, Wen W, Xueping E, Klein S, Semenkovich CF, Bae KT, Quirk EK, Powderly WG, Yarasheski KE, Li E. Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based highly active antiretroviral therapy. Metabolism. 2005 May; 54(5):561-7. PMID: 15877283; PMCID: PMC1564433.
    20. Kelley DE, Bray GA, Pi-Sunyer FX, Klein S, Hill J, Miles J, Hollander P. Clinical efficacy of orlistat therapy in overweight and obese patients with insulin-treated type 2 diabetes: A 1-year randomized controlled trial. Diabetes Care. 2002 Jun; 25(6):1033-41. PMID: 12032111.
      View in: PubMed
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