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    Sameh Ali

    TitleAssociate Adjunct Professor
    SchoolUniversity of California, San Diego
    DepartmentAnesthesiology
    Address9500 Gilman Drive #9125
    CA La Jolla 92093
    Phone858-552-8585
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Abdel-Rahman EA, Mahmoud AM, Aaliya A, Radwan Y, Yasseen B, Al-Okda A, Atwa A, Elhanafy E, Habashy M, Ali S. Resolving Contributions of Oxygen-Consuming and ROS-Generating Enzymes at the Synapse. Oxid Med Cell Longev. 2016; 2016:1089364. PMID: 28003863.
        View in: PubMed
      2. A Abdel-Rahman E, Mahmoud AM, Khalifa AM, Ali S. Physiological and pathophysiological reactive oxygen species as probed by EPR spectroscopy: the underutilized research window on muscle ageing. J Physiol. 2016 Aug 15; 594(16):4591-613. PMID: 26801204.
        View in: PubMed
      3. Jiang J, Chan A, Ali S, Saha A, Haushalter KJ, Lam WL, Glasheen M, Parker J, Brenner M, Mahon SB, Patel HH, Ambasudhan R, Lipton SA, Pilz RB, Boss GR. Hydrogen Sulfide-Mechanisms of Toxicity and Development of an Antidote. Sci Rep. 2016; 6:20831. PMID: 26877209.
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      4. Zúñiga-Hertz JP, Rebelato E, Kassan A, Khalifa AM, Ali S, Patel HH, Abdulkader F. Distinct pathways of cholesterol biosynthesis impact on insulin secretion. J Endocrinol. 2015 Jan; 224(1):75-84. PMID: 25453115.
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      5. Niesman IR, Schilling JM, Shapiro LA, Kellerhals SE, Bonds JA, Kleschevnikov AM, Cui W, Voong A, Krajewski S, Ali S, Roth DM, Patel HH, Patel PM, Head BP. Traumatic brain injury enhances neuroinflammation and lesion volume in caveolin deficient mice. J Neuroinflammation. 2014; 11(1):39. PMID: 24593993.
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      6. Dugan LL, You YH, Ali S, Diamond-Stanic M, Miyamoto S, Decleves AE, Andreyev A, Quach T, Ly S, Shekhtman G, Nguyen W, Chepetan A, Le TP, Wang L, Xu M, Paik KP, Fogo A, Viollet B, Murphy A, Brosius F, Naviaux RK, Sharma K. AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function. J Clin Invest. 2013 Nov 1; 123(11):4888-99. PMID: 24135141.
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      7. Panneerselvam M, Ali S, Finley JC, Kellerhals SE, Migita MY, Head BP, Patel PM, Roth DM, Patel HH. Epicatechin regulation of mitochondrial structure and function is opioid receptor dependent. Mol Nutr Food Res. 2013 Jun; 57(6):1007-14. PMID: 23625721.
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      8. Sastri M, Haushalter KJ, Panneerselvam M, Chang P, Fridolfsson H, Finley JC, Ng D, Schilling JM, Miyanohara A, Day ME, Hakozaki H, Petrosyan S, Koller A, King CC, Darshi M, Blumenthal DK, Ali S, Roth DM, Patel HH, Taylor SS. A kinase interacting protein (AKIP1) is a key regulator of cardiac stress. Proc Natl Acad Sci U S A. 2013 Jan 29; 110(5):E387-96. PMID: 23319652.
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      9. Fridolfsson HN, Kawaraguchi Y, Ali S, Panneerselvam M, Niesman IR, Finley JC, Kellerhals SE, Migita MY, Okada H, Moreno AL, Jennings M, Kidd MW, Bonds JA, Balijepalli RC, Ross RS, Patel PM, Miyanohara A, Chen Q, Lesnefsky EJ, Head BP, Roth DM, Insel PA, Patel HH. Mitochondria-localized caveolin in adaptation to cellular stress and injury. FASEB J. 2012 Nov; 26(11):4637-49. PMID: 22859372.
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      10. Tsai CY, Finley JC, Ali S, Patel HH, Howell SB. Copper influx transporter 1 is required for FGF, PDGF and EGF-induced MAPK signaling. Biochem Pharmacol. 2012 Oct 15; 84(8):1007-13. PMID: 22842628.
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      11. Ali S, Hsiao M, Zhao HW, Dugan LL, Haddad GG, Zhou D. Hypoxia-adaptation involves mitochondrial metabolic depression and decreased ROS leakage. PLoS One. 2012; 7(5):e36801. PMID: 22574227.
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      12. Pamenter ME, Ali S, Tang Q, Finley JC, Gu XQ, Dugan LL, Haddad GG. An in vitro ischemic penumbral mimic perfusate increases NADPH oxidase-mediated superoxide production in cultured hippocampal neurons. Brain Res. 2012 May 3; 1452:165-72. PMID: 22459046.
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      13. Zhao HW, Ali S, Haddad GG. Does hyperoxia selection cause adaptive alterations of mitochondrial electron transport chain activity leading to a reduction of superoxide production? Antioxid Redox Signal. 2012 May 15; 16(10):1071-6. PMID: 22229946.
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      14. Kawaraguchi Y, Horikawa YT, Murphy AN, Murray F, Miyanohara A, Ali S, Head BP, Patel PM, Roth DM, Patel HH. Volatile anesthetics protect cancer cells against tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via caveolins. Anesthesiology. 2011 Sep; 115(3):499-508. PMID: 21862885.
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      15. Head BP, Hu Y, Finley JC, Saldana MD, Bonds JA, Miyanohara A, Niesman IR, Ali S, Murray F, Insel PA, Roth DM, Patel HH, Patel PM. Neuron-targeted caveolin-1 protein enhances signaling and promotes arborization of primary neurons. J Biol Chem. 2011 Sep 23; 286(38):33310-21. PMID: 21799010.
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      16. Horikawa YT, Panneerselvam M, Kawaraguchi Y, Tsutsumi YM, Ali S, Balijepalli RC, Murray F, Head BP, Niesman IR, Rieg T, Vallon V, Insel PA, Patel HH, Roth DM. Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signaling. J Am Coll Cardiol. 2011 May 31; 57(22):2273-83. PMID: 21616289.
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      17. Head BP, Peart JN, Panneerselvam M, Yokoyama T, Pearn ML, Niesman IR, Bonds JA, Schilling JM, Miyanohara A, Headrick J, Ali S, Roth DM, Patel PM, Patel HH. Loss of caveolin-1 accelerates neurodegeneration and aging. PLoS One. 2010; 5(12):e15697. PMID: 21203469.
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      18. Ali S, Young JW, Wallace CK, Gresack J, Jeste DV, Geyer MA, Dugan LL, Risbrough VB. Initial evidence linking synaptic superoxide production with poor short-term memory in aged mice. Brain Res. 2011 Jan 12; 1368:65-70. PMID: 21075081.
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      19. Ali S, Marcondes MC, Bajova H, Dugan LL, Conti B. Metabolic depression and increased reactive oxygen species production by isolated mitochondria at moderately lower temperatures. J Biol Chem. 2010 Oct 15; 285(42):32522-8. PMID: 20716522.
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      20. Douglas RM, Ryu J, Kanaan A, Del Carmen Rivero M, Dugan LL, Haddad GG, Ali S. Neuronal death during combined intermittent hypoxia/hypercapnia is due to mitochondrial dysfunction. Am J Physiol Cell Physiol. 2010 Jun; 298(6):C1594-602. PMID: 20357179.
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      21. Dugan LL, Ali S, Shekhtman G, Roberts AJ, Lucero J, Quick KL, Behrens MM. IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase. PLoS One. 2009; 4(5):e5518. PMID: 19436757.
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      22. Behrens MM, Ali S, Dugan LL. Interleukin-6 mediates the increase in NADPH-oxidase in the ketamine model of schizophrenia. J Neurosci. 2008 Dec 17; 28(51):13957-66. PMID: 19091984.
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      23. Ali S, Hardt JI, Dugan LL. SOD activity of carboxyfullerenes predicts their neuroprotective efficacy: a structure-activity study. Nanomedicine. 2008 Dec; 4(4):283-94. PMID: 18656425.
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      24. Cuddihy SL, Ali S, Musiek ES, Lucero J, Kopp SJ, Morrow JD, Dugan LL. Prolonged alpha-tocopherol deficiency decreases oxidative stress and unmasks alpha-tocopherol-dependent regulation of mitochondrial function in the brain. J Biol Chem. 2008 Mar 14; 283(11):6915-24. PMID: 18180306.
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      25. Behrens MM, Ali S, Dao DN, Lucero J, Shekhtman G, Quick KL, Dugan LL. Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase. Science. 2007 Dec 7; 318(5856):1645-7. PMID: 18063801.
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      26. Ali S, Xiong C, Lucero J, Behrens MM, Dugan LL, Quick KL. Gender differences in free radical homeostasis during aging: shorter-lived female C57BL6 mice have increased oxidative stress. Aging Cell. 2006 Dec; 5(6):565-74. PMID: 17129217.
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      27. Quick KL, Ali S, Arch R, Xiong C, Wozniak D, Dugan LL. A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice. Neurobiol Aging. 2008 Jan; 29(1):117-28. PMID: 17079053.
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      28. Ali S, Hardt JI, Quick KL, Kim-Han JS, Erlanger BF, Huang TT, Epstein CJ, Dugan LL. A biologically effective fullerene (C60) derivative with superoxide dismutase mimetic properties. Free Radic Biol Med. 2004 Oct 15; 37(8):1191-202. PMID: 15451059.
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