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Ryan Trim

Title(s)Associate Professor, Psychiatry
SchoolHealth Sciences
Phone858-642-3693
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    Collapse Biography 
    Collapse Education and Training
    University of North Carolina, Chapel Hill, NCBS05/2000Psychology
    Arizona State University, Tempe, AZMA06/2002Clinical Psychology
    Arizona State University, Tempe, AZPhD06/2007Clinical Psychology

    Collapse Overview 
    Collapse Overview
    Broadly, I am interested in the impact of individual and environmental risk factors on substance use and related high-risk behaviors across the lifespan. My primary research interest focuses on the onset, maintenance, and escalation of substance use in adolescence and young adulthood from a developmental psychopathology perspective. My current NIAAA grant examines cognitive factors and brain functioning associated with various levels of alcohol-tobacco co-use involvement among young adults. Clinically, I serve as director of the Substance Abuse/Mental Illness (SAMI) Clinic at the VA San Diego where I oversee the development, application, and teaching of integrated treatment approaches for veterans with co-occurring psychiatric and substance use disorders. As such, I have an overarching passion for enhancing our understanding and treatment of complex substance use comorbidities both as a researcher and clinician.

    Collapse Research 
    Collapse Research Activities and Funding
    Motives for Simultaneous Alcohol and Tobacco Use in Young Adults
    NIH/NIAAA R21AA021822Sep 10, 2013 - Aug 31, 2015
    Role: Principal Investigator

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    Collapse Featured Publications

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Curry I, Trim RS, Brown SA, Hopfer CJ, Stallings MC, Wall TL. Positive expectancies mediate the association between sensation seeking and marijuana outcomes in at-risk young adults: A test of the acquired preparedness model. Am J Addict. 2018 Jun 06. PMID: 29873863.
      View in: PubMed
    2. Trim RS, Doran N. Simultaneous alcohol & tobacco use expectancies in young adult co-users. Addict Behav. 2018 Feb; 77:96-99. PMID: 28992581.
      View in: PubMed
    3. Curry I, Luk JW, Trim RS, Hopfer CJ, Hewitt JK, Stallings MC, Brown SA, Wall TL. Impulsivity Dimensions and Risky Sex Behaviors in an At-Risk Young Adult Sample. Arch Sex Behav. 2018 Feb; 47(2):529-536. PMID: 28884246.
      View in: PubMed
    4. Siegel EY, Haller M, Cui R, Trim RS, Tate SR, Norman SB. Examining changes in negative mood regulation expectancies, posttraumatic stress disorder, depression, and substance use following integrated cognitive-behavioral therapy. Subst Abus. 2017 Oct-Dec; 38(4):468-472. PMID: 28632462.
      View in: PubMed
    5. Luk JW, Trim RS, Karyadi KA, Curry I, Hopfer CJ, Hewitt JK, Stallings MC, Brown SA, Wall TL. Unique and interactive effects of impulsivity facets on reckless driving and driving under the influence in a high-risk young adult sample. Pers Individ Dif. 2017 Aug 01; 114:42-47. PMID: 29038610.
      View in: PubMed
    6. Luk JW, Worley MJ, Winiger E, Trim RS, Hopfer CJ, Hewitt JK, Brown SA, Wall TL. Risky driving and sexual behaviors as developmental outcomes of co-occurring substance use and antisocial behavior. Drug Alcohol Depend. 2016 12 01; 169:19-25. PMID: 27750183.
      View in: PubMed
    7. Haller M, Colvonen PJ, Davis BC, Trim RS, Bogner R, Sevcik J, Norman SB. Examining Pretreatment Differences Between Veterans in Residential Versus Outpatient Treatment for Alcohol Use Disorder and Comorbid Combat-Related PTSD. J Dual Diagn. 2016 Jul-Dec; 12(3-4):282-289. PMID: 27808661.
      View in: PubMed
    8. Choi TK, Worley MJ, Trim RS, Howard D, Brown SA, Hopfer CJ, Hewitt JK, Wall TL. Effect of adolescent substance use and antisocial behavior on the development of early adulthood depression. Psychiatry Res. 2016 Apr 30; 238:143-149. PMID: 27086224.
      View in: PubMed
    9. Haller M, Norman SB, Cummins K, Trim RS, Xu X, Cui R, Allard CB, Brown SA, Tate SR. Integrated Cognitive Behavioral Therapy Versus Cognitive Processing Therapy for Adults With Depression, Substance Use Disorder, and Trauma. J Subst Abuse Treat. 2016 Mar; 62:38-48. PMID: 26718130.
      View in: PubMed
    10. Doran N, Trim RS. Correlates of other tobacco use in a community sample of young adults. Addict Behav. 2015 Dec; 51:131-5. PMID: 26255638; PMCID: PMC4558378 [Available on 12/01/16].
      View in: PubMed, PubMed Central
    11. Norman SB, Haller M, Spadoni AD, Drummond SP, Risbrough V, Hamblen JL, Trim RS, Blanes EX. Maximizing the utility of a single site randomized controlled psychotherapy trial. Contemp Clin Trials. 2015 May; 42:244-51. PMID: 25933919.
      View in: PubMed
    12. Browne KC, Trim RS, Myers US, Norman SB. Trauma-related guilt: conceptual development and relationship with posttraumatic stress and depressive symptoms. J Trauma Stress. 2015 Apr; 28(2):134-41. PMID: 25864504.
      View in: PubMed
    13. Trim RS, Worley MJ, Wall TL, Hopfer CJ, Crowley TJ, Hewitt JK, Brown SA. Bivariate Trajectories of Substance Use and Antisocial Behavior: Associations with Emerging Adult Outcomes in a High-Risk Sample. Emerg Adulthood. 2015 Aug 01; 3(4):265-276. PMID: 26889401.
      View in: PubMed
    14. Trim, R.S., Worley, M.J., Wall, T.L., Hopfer, C.J., Crowley, T.J., Hewitt, J.K., Brown, S.A.Bivariate trajectories of substance use and antisocial behavior: Associations with emerging adult outcomes in a high-risk sample. Emerging Adulthood. 2015; 4(3):265-276.
      View Publication
    15. Worley MJ, Trim RS, Tate SR, Roesch SC, Myers MG, Brown SA. Self-efficacy and social networks after treatment for alcohol or drug dependence and major depression: disentangling person and time-level effects. Psychol Addict Behav. 2014 Dec; 28(4):1220-9. PMID: 25347018; PMCID: PMC4651972.
      View in: PubMed, PubMed Central
    16. Doran N, Trim RS. The prospective effects of impulsivity on alcohol and tobacco use in a college sample. J Psychoactive Drugs. 2013 Nov-Dec; 45(5):379-85. PMID: 24592663.
      View in: PubMed
    17. Swerdlow NR, Light GA, Trim RS, Breier MR, Hines SR, Powell SB. Forebrain gene expression predicts deficits in sensorimotor gating after isolation rearing in male rats. Behav Brain Res. 2013 Nov 15; 257:118-28. PMID: 24076151; PMCID: PMC3897308.
      View in: PubMed, PubMed Central
    18. Trim RS, Schuckit MA, Smith TL. Predictors of initial and sustained remission from alcohol use disorders: findings from the 30-year follow-up of the San Diego Prospective Study. Alcohol Clin Exp Res. 2013 Aug; 37(8):1424-31. PMID: 23458300; PMCID: PMC3675188.
      View in: PubMed, PubMed Central
    19. Norman SB, Allard CB, Trim RS, Thorp SR, Behrooznia M, Masino TT, Stein MB. Psychometrics of the Overall Anxiety Severity and Impairment Scale (OASIS) in a sample of women with and without trauma histories. Arch Womens Ment Health. 2013 Apr; 16(2):123-9. PMID: 23296334.
      View in: PubMed
    20. Schuckit MA, Smith TL, Trim RS, Kuperman S, Kramer J, Hesselbrock V, Bucholz KK, Nurnberger JI, Hesselbrock M, Saunders G. Sex differences in how a low sensitivity to alcohol relates to later heavy drinking. Drug Alcohol Rev. 2012 Nov; 31(7):871-80. PMID: 22708705; PMCID: PMC3459074.
      View in: PubMed, PubMed Central
    21. Swerdlow NR, Shilling PD, Breier M, Trim RS, Light GA, Marie RS. Fronto-temporal-mesolimbic gene expression and heritable differences in amphetamine-disrupted sensorimotor gating in rats. Psychopharmacology (Berl). 2012 Dec; 224(3):349-62. PMID: 22700037.
      View in: PubMed
    22. Doran N, Khoddam R, Sanders PE, Schweizer CA, Trim RS, Myers MG. A prospective study of the Acquired Preparedness Model: the effects of impulsivity and expectancies on smoking initiation in college students. Psychol Addict Behav. 2013 Sep; 27(3):714-22. PMID: 22686965; PMCID: PMC4779050.
      View in: PubMed, PubMed Central
    23. Paulus MP, Schuckit MA, Tapert SF, Tolentino NJ, Matthews SC, Smith TL, Trim RS, Hall SA, Simmons AN. High versus low level of response to alcohol: evidence of differential reactivity to emotional stimuli. Biol Psychiatry. 2012 Nov 15; 72(10):848-55. PMID: 22608014; PMCID: PMC3433640.
      View in: PubMed, PubMed Central
    24. Jacobus J, Thayer RE, Trim RS, Bava S, Frank LR, Tapert SF. White matter integrity, substance use, and risk taking in adolescence. Psychol Addict Behav. 2013 Jun; 27(2):431-42. PMID: 22564204.
      View in: PubMed
    25. Worley MJ, Trim RS, Roesch SC, Mrnak-Meyer J, Tate SR, Brown SA. Comorbid depression and substance use disorder: longitudinal associations between symptoms in a controlled trial. J Subst Abuse Treat. 2012 Oct; 43(3):291-302. PMID: 22406052; PMCID: PMC3382030.
      View in: PubMed, PubMed Central
    26. Schuckit MA, Smith TL, Kalmijn J, Trim RS, Cesario E, Saunders G, Sanchez C, Campbell N. Comparison across two generations of prospective models of how the low level of response to alcohol affects alcohol outcomes. J Stud Alcohol Drugs. 2012 Mar; 73(2):195-204. PMID: 22333327; PMCID: PMC3281979.
      View in: PubMed, PubMed Central
    27. Schuckit MA, Tapert S, Matthews SC, Paulus MP, Tolentino NJ, Smith TL, Trim RS, Hall S, Simmons A. fMRI differences between subjects with low and high responses to alcohol during a stop signal task. Alcohol Clin Exp Res. 2012 01; 36(1):130-40. PMID: 22003983; PMCID: PMC3253183.
      View in: PubMed, PubMed Central
    28. Bekman NM, Anderson KG, Trim RS, Metrik J, Diulio AR, Myers MG, Brown SA. Thinking and drinking: alcohol-related cognitions across stages of adolescent alcohol involvement. Psychol Addict Behav. 2011 Sep; 25(3):415-25. PMID: 21534645; PMCID: PMC3372460.
      View in: PubMed, PubMed Central
    29. Norman SB, Trim RS, Goldsmith AA, Dimsdale JE, Hoyt DB, Norman GJ, Stein MB. Role of risk factors proximate to time of trauma in the course of PTSD and MDD symptoms following traumatic injury. J Trauma Stress. 2011 Aug; 24(4):390-8. PMID: 21834085.
      View in: PubMed
    30. Reed MB, Clapp JD, Weber M, Trim R, Lange J, Shillington AM. Predictors of partying prior to bar attendance and subsequent BrAC. Addict Behav. 2011 Dec; 36(12):1341-3. PMID: 21862231.
      View in: PubMed
    31. Schuckit MA, Smith TL, Trim RS, Allen RC, Fukukura T, Knight EE, Cesario EM, Kreikebaum SA. A prospective evaluation of how a low level of response to alcohol predicts later heavy drinking and alcohol problems. Am J Drug Alcohol Abuse. 2011 Nov; 37(6):479-86. PMID: 21797810.
      View in: PubMed
    32. Trim RS, Clapp JD, Reed MB, Shillington A, Thombs D. Drinking plans and drinking outcomes: examining young adults' weekend drinking behavior. J Drug Educ. 2011; 41(3):253-70. PMID: 22125921.
      View in: PubMed
    33. Worley MJ, Trim RS, Tate SR, Hall JE, Brown SA. Service utilization during and after outpatient treatment for comorbid substance use disorder and depression. J Subst Abuse Treat. 2010 Sep; 39(2):124-31. PMID: 20598832.
      View in: PubMed
    34. Trim RS, Simmons AN, Tolentino NJ, Hall SA, Matthews SC, Robinson SK, Smith TL, Padula CB, Paulus MP, Tapert SF, Schuckit MA. Acute ethanol effects on brain activation in low- and high-level responders to alcohol. Alcohol Clin Exp Res. 2010 Jul; 34(7):1162-70. PMID: 20477775; PMCID: PMC3774836.
      View in: PubMed, PubMed Central
    35. Schuckit MA, Smith TL, Trim RS, Tolentino NJ, Hall SA. Comparing structural equation models that use different measures of the level of response to alcohol. Alcohol Clin Exp Res. 2010 May; 34(5):861-8. PMID: 20201931.
      View in: PubMed
    36. Trim RS, Schuckit MA, Smith TL. Predicting drinking onset with discrete-time survival analysis in offspring from the San Diego prospective study. Drug Alcohol Depend. 2010 Mar 01; 107(2-3):215-20. PMID: 19959300; PMCID: PMC2822001.
      View in: PubMed, PubMed Central
    37. Clapp JD, Min JW, Trim RS, Reed MB, Lange JE, Shillington AM, Croff JM. Predictors of error in estimates of blood alcohol concentration: a replication. J Stud Alcohol Drugs. 2009 Sep; 70(5):683-8. PMID: 19737492; PMCID: PMC2741548.
      View in: PubMed, PubMed Central
    38. Trim RS, Schuckit MA, Smith TL. The relationships of the level of response to alcohol and additional characteristics to alcohol use disorders across adulthood: a discrete-time survival analysis. Alcohol Clin Exp Res. 2009 Sep; 33(9):1562-70. PMID: 19485971; PMCID: PMC2947374.
      View in: PubMed, PubMed Central
    39. Schuckit MA, Smith TL, Danko GP, Trim R, Bucholz KK, Edenberg HJ, Hesselbrock V, Kramer JJ, Dick DM. An evaluation of the full level of response to alcohol model of heavy drinking and problems in COGA offspring. J Stud Alcohol Drugs. 2009 May; 70(3):436-45. PMID: 19371495; PMCID: PMC2670749.
      View in: PubMed, PubMed Central
    40. Clapp JD, Reed MB, Min JW, Shillington AM, Croff JM, Holmes MR, Trim RS. Blood alcohol concentrations among bar patrons: A multi-level study of drinking behavior. Drug Alcohol Depend. 2009 Jun 01; 102(1-3):41-8. PMID: 19250775; PMCID: PMC2674139.
      View in: PubMed, PubMed Central
    41. Schuckit MA, Smith TL, Trim R, Fukukura T, Allen R. The overlap in predicting alcohol outcome for two measures of the level of response to alcohol. Alcohol Clin Exp Res. 2009 Mar; 33(3):563-9. PMID: 19120060; PMCID: PMC2651993.
      View in: PubMed, PubMed Central
    42. Schuckit MA, Smith TL, Trim RS, Heron J, Horwood J, Davis J, Hibbeln J. The self-rating of the effects of alcohol questionnaire as a predictor of alcohol-related outcomes in 12-year-old subjects. Alcohol Alcohol. 2008 Nov-Dec; 43(6):641-6. PMID: 18845530; PMCID: PMC2720769.
      View in: PubMed, PubMed Central
    43. Schuckit MA, Smith TL, Trim R, Heron J, Horwood J, Davis JM, Hibbeln JR. The performance of elements of a 'level of response to alcohol'-based model of drinking behaviors in 13-year-olds. Addiction. 2008 Nov; 103(11):1786-92. PMID: 18778389; PMCID: PMC2588481.
      View in: PubMed, PubMed Central
    44. Trim RS, Chassin L. Neighborhood socioeconomic status effects on adolescent alcohol outcomes using growth models: exploring the role of parental alcoholism. J Stud Alcohol Drugs. 2008 Sep; 69(5):639-48. PMID: 18781238; PMCID: PMC2575391.
      View in: PubMed, PubMed Central
    45. Schuckit MA, Smith TL, Trim R, Kreikebaum S, Hinga B, Allen R. Testing the level of response to alcohol-based model of heavy drinking and alcohol problems in offspring from the San Diego Prospective Study. J Stud Alcohol Drugs. 2008 Jul; 69(4):571-9. PMID: 18612573.
      View in: PubMed
    46. Schuckit MA, Danko GP, Smith TL, Bierut LJ, Bucholz KK, Edenberg HJ, Hesselbrock V, Kramer J, Nurnberger JI, Trim R, Allen R, Kreikebaum S, Hinga B. The prognostic implications of DSM-IV abuse criteria in drinking adolescents. Drug Alcohol Depend. 2008 Sep 01; 97(1-2):94-104. PMID: 18479842; PMCID: PMC2581466.
      View in: PubMed, PubMed Central
    47. Trim RS, Schuckit MA, Smith TL. Level of response to alcohol within the context of alcohol-related domains: an examination of longitudinal approaches assessing changes over time. Alcohol Clin Exp Res. 2008 Mar; 32(3):472-80. PMID: 18302725.
      View in: PubMed
    48. Schuckit MA, Smith TL, Hesselbrock V, Bucholz KK, Bierut L, Edenberg H, Kramer J, Longacre E, Fukukura T, Kalmijn J, Danko GP, Trim R. Clinical implications of tolerance to alcohol in nondependent young drinkers. Am J Drug Alcohol Abuse. 2008; 34(2):133-49. PMID: 18293230.
      View in: PubMed
    49. Schuckit MA, Smith TL, Danko GP, Pierson J, Trim R, Nurnberger JI, Kramer J, Kuperman S, Bierut LJ, Hesselbrock V. A comparison of factors associated with substance-induced versus independent depressions. J Stud Alcohol Drugs. 2007 Nov; 68(6):805-12. PMID: 17960298.
      View in: PubMed
    50. Schuckit MA, Smith TL, Pierson J, Trim R, Danko GP. Externalizing disorders in the offspring from the San Diego prospective study of alcoholism. J Psychiatr Res. 2008 Jul; 42(8):644-52. PMID: 17765266; PMCID: PMC2414261.
      View in: PubMed, PubMed Central
    51. Trim RS, Meehan BT, King KM, Chassin L. The relation between adolescent substance use and young adult internalizing symptoms: findings from a high-risk longitudinal sample. Psychol Addict Behav. 2007 Mar; 21(1):97-107. PMID: 17385959.
      View in: PubMed
    52. King KM, Meehan BT, Trim RS, Chassin L. Substance use and academic outcomes: Synthesizing findings and future directions. Addiction. 2006 Dec; 101(12):1688-9. PMID: 17156166; PMCID: PMC2156039.
      View in: PubMed, PubMed Central
    53. King KM, Meehan BT, Trim RS, Chassin L. Marker or mediator? The effects of adolescent substance use on young adult educational attainment. Addiction. 2006 Dec; 101(12):1730-40. PMID: 17156172; PMCID: PMC2238681.
      View in: PubMed, PubMed Central
    54. Trim RS, Leuthe E, Chassin L. Sibling influence on alcohol use in a young adult, high-risk sample. J Stud Alcohol. 2006 May; 67(3):391-8. PMID: 16608148.
      View in: PubMed
    55. Trim RS, Chassin L. Drinking restraint, alcohol consumption and alcohol dependence among children of alcoholics. J Stud Alcohol. 2004 Jan; 65(1):122-5. PMID: 15000511.
      View in: PubMed
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