Ryan Hard

Title(s)Assistant Project Scientist, Chemistry and Biochemistry
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. RESP2: An uncertainty aware multi-target multi-property optimization AI pipeline for antibody discovery. bioRxiv. 2024 Jul 31. Parkinson J, Hard R, Ko YS, Wang W. PMID: 39131296; PMCID: PMC11312550.
      View in: PubMed   Mentions:
    2. The RESP AI model accelerates the identification of tight-binding antibodies. Nat Commun. 2023 01 28; 14(1):454. Parkinson J, Hard R, Wang W. PMID: 36709319; PMCID: PMC9884274.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    3. Engineering human JMJD2A tudor domains for an improved understanding of histone peptide recognition. Proteins. 2023 01; 91(1):32-46. Parkinson J, Hard R, Ainsworth R, Wang W. PMID: 35927178; PMCID: PMC9771871.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Engineering a Histone Reader Protein by Combining Directed Evolution, Sequencing, and Neural Network Based Ordinal Regression. J Chem Inf Model. 2020 08 24; 60(8):3992-4004. Parkinson J, Hard R, Ainsworth RI, Li N, Wang W. PMID: 32786513.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    5. Deciphering and engineering chromodomain-methyllysine peptide recognition. Sci Adv. 2018 11; 4(11):eaau1447. Hard R, Li N, He W, Ross B, Mo GCH, Peng Q, Stein RSL, Komives E, Wang Y, Zhang J, Wang W. PMID: 30417094; PMCID: PMC6221542.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    6. Discovery and Mechanism of Highly Efficient Cyclic Cell-Penetrating Peptides. Biochemistry. 2016 05 10; 55(18):2601-12. Qian Z, Martyna A, Hard RL, Wang J, Appiah-Kubi G, Coss C, Phelps MA, Rossman JS, Pei D. PMID: 27089101; PMCID: PMC8562596.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansAnimalsCells
    7. Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery. Biochemistry. 2014 Jun 24; 53(24):4034-46. Qian Z, LaRochelle JR, Jiang B, Lian W, Hard RL, Selner NG, Luechapanichkul R, Barrios AM, Pei D. PMID: 24896852; PMCID: PMC4075989.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    8. Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry. 2011 Sep 06; 50(35):7637-46. Zhang Y, Zhang J, Yuan C, Hard RL, Park IH, Li C, Bell C, Pei D. PMID: 21800896; PMCID: PMC3164524.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    9. Distinct ligand specificity of the Tiam1 and Tiam2 PDZ domains. Biochemistry. 2011 Mar 01; 50(8):1296-308. Shepherd TR, Hard RL, Murray AM, Pei D, Fuentes EJ. PMID: 21192692; PMCID: PMC3059893.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    10. HDAC6 and Ubp-M BUZ domains recognize specific C-terminal sequences of proteins. Biochemistry. 2010 Dec 21; 49(50):10737-46. Hard RL, Liu J, Shen J, Zhou P, Pei D. PMID: 21090589; PMCID: PMC3005221.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
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