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    Rolf Bodmer

    TitleAdjunct Professor
    SchoolUniversity of California, San Diego
    DepartmentPediatrics
    Address9500 Gilman Drive #0831
    CA La Jolla 92093
    Phone858-246-0009
    vCardDownload vCard

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Gan Z, Powell FL, Zambon AC, Buchholz KS, Fu Z, Ocorr K, Bodmer R, Moya EA, Stowe JC, Haddad GG, McCulloch AD. Transcriptomic analysis identifies a role of PI3K-Akt signalling in the responses of skeletal muscle to acute hypoxia in vivo. J Physiol. 2017 Sep 01; 595(17):5797-5813. PMID: 28688178.
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      2. Zanon A, Kalvakuri S, Rakovic A, Foco L, Guida M, Schwienbacher C, Serafin A, Rudolph F, Trilck M, Grünewald A, Stanslowsky N, Wegner F, Giorgio V, Lavdas AA, Bodmer R, Pramstaller PP, Klein C, Hicks AA, Pichler I, Seibler P. SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila. Hum Mol Genet. 2017 Jul 01; 26(13):2412-2425. PMID: 28379402.
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      3. Cannon L, Zambon AC, Cammarato A, Zhang Z, Vogler G, Munoz M, Taylor E, Cartry J, Bernstein SI, Melov S, Bodmer R. Expression patterns of cardiac aging in Drosophila. Aging Cell. 2017 Feb; 16(1):82-92. PMID: 28090760.
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      4. Blice-Baum AC, Zambon AC, Kaushik G, Viswanathan MC, Engler AJ, Bodmer R, Cammarato A. Modest overexpression of FOXO maintains cardiac proteostasis and ameliorates age-associated functional decline. Aging Cell. 2017 Feb; 16(1):93-103. PMID: 28090761.
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      5. Shahrestani P, Burke MK, Birse R, Kezos JN, Ocorr K, Mueller LD, Rose MR, Bodmer R. Experimental Evolution and Heart Function in Drosophila. Physiol Biochem Zool. 2017 Mar/Apr; 90(2):281-293. PMID: 28277957.
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      6. Sessions AO, Kaushik G, Parker S, Raedschelders K, Bodmer R, Van Eyk JE, Engler AJ. Extracellular matrix downregulation in the Drosophila heart preserves contractile function and improves lifespan. Matrix Biol. 2016 Oct 25. PMID: 27793636.
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      7. van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano MT, Wang X, Mateo Leach I, Eijgelsheim M, Sotoodehnia N, Hayward C, Sorice R, Meirelles O, Lyytikäinen LP, Polašek O, Tanaka T, Arking DE, Ulivi S, Trompet S, Müller-Nurasyid M, Smith AV, Dörr M, Kerr KF, Magnani JW, Del Greco M F, Zhang W, Nolte IM, Silva CT, Padmanabhan S, Tragante V, Esko T, Abecasis GR, Adriaens ME, Andersen K, Barnett P, Bis JC, Bodmer R, Buckley BM, Campbell H, Cannon MV, Chakravarti A, Chen LY, Delitala A, Devereux RB, Doevendans PA, Dominiczak AF, Ferrucci L, Ford I, Gieger C, Harris TB, Haugen E, Heinig M, Hernandez DG, Hillege HL, Hirschhorn JN, Hofman A, Hubner N, Hwang SJ, Iorio A, Kähönen M, Kellis M, Kolcic I, Kooner IK, Kooner JS, Kors JA, Lakatta EG, Lage K, Launer LJ, Levy D, Lundby A, Macfarlane PW, May D, Meitinger T, Metspalu A, Nappo S, Naitza S, Neph S, Nord AS, Nutile T, Okin PM, Olsen JV, Oostra BA, Penninger JM, Pennacchio LA, Pers TH, Perz S, Peters A, Pinto YM, Pfeufer A, Pilia MG, Pramstaller PP, Prins BP, Raitakari OT, Raychaudhuri S, Rice KM, Rossin EJ, Rotter JI, Schafer S, Schlessinger D, Schmidt CO, Sehmi J, Silljé HHW, Sinagra G, Sinner MF, Slowikowski K, Soliman EZ, Spector TD, Spiering W, Stamatoyannopoulos JA, Stolk RP, Strauch K, Tan ST, Tarasov KV, Trinh B, Uitterlinden AG, van den Boogaard M, van Duijn CM, van Gilst WH, Viikari JS, Visscher PM, Vitart V, Völker U, Waldenberger M, Weichenberger CX, Westra HJ, Wijmenga C, Wolffenbuttel BH, Yang J, Bezzina CR, Munroe PB, Snieder H, Wright AF, Rudan I, Boyer LA, Asselbergs FW, van Veldhuisen DJ, Stricker BH, Psaty BM, Ciullo M, Sanna S, Lehtimäki T, Wilson JF, Bandinelli S, Alonso A, Gasparini P, Jukema JW, Kääb S, Gudnason V, Felix SB, Heckbert SR, de Boer RA, Newton-Cheh C, Hicks AA, Chambers JC, Jamshidi Y, Visel A, Christoffels VM, Isaacs A, Samani NJ, de Bakker PIW. 52 Genetic Loci Influencing Myocardial Mass. J Am Coll Cardiol. 2016 Sep 27; 68(13):1435-1448. PMID: 27659466.
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      8. Achal M, Trujillo AS, Melkani GC, Farman GP, Ocorr K, Viswanathan MC, Kaushik G, Newhard CS, Glasheen BM, Melkani A, Suggs JA, Moore JR, Swank DM, Bodmer R, Cammarato A, Bernstein SI. A Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in Drosophila. J Mol Biol. 2016 Jun 05; 428(11):2446-61. PMID: 27107639; PMCID: PMC4884507 [Available on 06/05/17].
      9. Trujillo GV, Nodal DH, Lovato CV, Hendren JD, Helander LA, Lovato TL, Bodmer R, Cripps RM. The canonical Wingless signaling pathway is required but not sufficient for inflow tract formation in the Drosophila melanogaster heart. Dev Biol. 2016 May 01; 413(1):16-25. PMID: 26983369; PMCID: PMC4834244 [Available on 05/01/17].
      10. Del Álamo JC, Lemons D, Serrano R, Savchenko A, Cerignoli F, Bodmer R, Mercola M. High throughput physiological screening of iPSC-derived cardiomyocytes for drug development. Biochim Biophys Acta. 2016 Jul; 1863(7 Pt B):1717-27. PMID: 26952934; PMCID: PMC4885786 [Available on 07/01/17].
      11. Hartley PS, Motamedchaboki K, Bodmer R, Ocorr K. SPARC-Dependent Cardiomyopathy in Drosophila. Circ Cardiovasc Genet. 2016 Apr; 9(2):119-29. PMID: 26839388; PMCID: PMC4838489.
      12. Diop SB, Bodmer R. Gaining Insights into Diabetic Cardiomyopathy from Drosophila. Trends Endocrinol Metab. 2015 Nov; 26(11):618-27. PMID: 26482877; PMCID: PMC4638170 [Available on 11/01/16].
      13. Zarndt R, Piloto S, Powell FL, Haddad GG, Bodmer R, Ocorr K. Cardiac responses to hypoxia and reoxygenation in Drosophila. Am J Physiol Regul Integr Comp Physiol. 2015 Dec 1; 309(11):R1347-57. PMID: 26377557.
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      14. Smith KA, Voiriot G, Tang H, Fraidenburg DR, Song S, Yamamura H, Yamamura A, Guo Q, Wan J, Pohl NM, Tauseef M, Bodmer R, Ocorr K, Thistlethwaite PA, Haddad GG, Powell FL, Makino A, Mehta D, Yuan JX. Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2015 Sep; 53(3):355-67. PMID: 25569851.
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      15. Ivy JR, Drechsler M, Catterson JH, Bodmer R, Ocorr K, Paululat A, Hartley PS. Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes. PLoS One. 2015; 10(8):e0134620. PMID: 26301956; PMCID: PMC4547745.
      16. Cannon L, Bodmer R. Genetic manipulation of cardiac ageing. J Physiol. 2016 Apr 15; 594(8):2075-83. PMID: 26060055; PMCID: PMC4933115 [Available on 04/15/17].
      17. Hardy CM, Birse RT, Wolf MJ, Yu L, Bodmer R, Gibbs AG. Obesity-associated cardiac dysfunction in starvation-selected Drosophila melanogaster. Am J Physiol Regul Integr Comp Physiol. 2015 Sep 15; 309(6):R658-67. PMID: 26136533; PMCID: PMC4591367.
      18. Kaushik G, Spenlehauer A, Sessions AO, Trujillo AS, Fuhrmann A, Fu Z, Venkatraman V, Pohl D, Tuler J, Wang M, Lakatta EG, Ocorr K, Bodmer R, Bernstein SI, Van Eyk JE, Cammarato A, Engler AJ. Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart. Sci Transl Med. 2015 Jun 17; 7(292):292ra99. PMID: 26084806.
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      19. Sen A, Kalvakuri S, Bodmer R, Cox RT. Clueless, a protein required for mitochondrial function, interacts with the PINK1-Parkin complex in Drosophila. Dis Model Mech. 2015 Jun; 8(6):577-89. PMID: 26035866; PMCID: PMC4457034.
      20. Martínez-Morentin L, Martínez L, Piloto S, Yang H, Schon EA, Garesse R, Bodmer R, Ocorr K, Cervera M, Arredondo JJ. Cardiac deficiency of single cytochrome oxidase assembly factor scox induces p53-dependent apoptosis in a Drosophila cardiomyopathy model. Hum Mol Genet. 2015 Jul 1; 24(13):3608-22. PMID: 25792727.
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      21. Diop SB, Bisharat-Kernizan J, Birse RT, Oldham S, Ocorr K, Bodmer R. PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase. Cell Rep. 2015 Mar 04. PMID: 25753422.
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      22. Vogler G, Bodmer R. Cellular Mechanisms of Drosophila Heart Morphogenesis. J Cardiovasc Dev Dis. 2015 Mar 01; 2(1):2-16. PMID: 26236710.
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      23. Trujillo AS, Ramos R, Bodmer R, Bernstein SI, Ocorr K, Melkani GC. Drosophila as a potential model to ameliorate mutant Huntington-mediated cardiac amyloidosis. Rare Dis. 2014; 2(1):e968003. PMID: 26942103; PMCID: PMC4755237.
      24. Vogler G, Liu J, Iafe TW, Migh E, Mihály J, Bodmer R. Cdc42 and formin activity control non-muscle myosin dynamics during Drosophila heart morphogenesis. J Cell Biol. 2014 Sep 29; 206(7):909-22. PMID: 25267295; PMCID: PMC4178965.
      25. Ocorr K, Vogler G, Bodmer R. Methods to assess Drosophila heart development, function and aging. Methods. 2014 Jun 15; 68(1):265-72. PMID: 24727147; PMCID: PMC4058868.
      26. Reed LK, Lee K, Zhang Z, Rashid L, Poe A, Hsieh B, Deighton N, Glassbrook N, Bodmer R, Gibson G. Systems genomics of metabolic phenotypes in wild-type Drosophila melanogaster. Genetics. 2014 Jun; 197(2):781-93. PMID: 24671769; PMCID: PMC4063932.
      27. Lim HY, Wang W, Chen J, Ocorr K, Bodmer R. ROS regulate cardiac function via a distinct paracrine mechanism. Cell Rep. 2014 Apr 10; 7(1):35-44. PMID: 24656823; PMCID: PMC4164050.
      28. Kumsta C, Ching TT, Nishimura M, Davis AE, Gelino S, Catan HH, Yu X, Chu CC, Ong B, Panowski SH, Baird N, Bodmer R, Hsu AL, Hansen M. Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1. Aging Cell. 2014 Jun; 13(3):419-30. PMID: 24314125; PMCID: PMC4059541.
      29. Nishimura M, Kumsta C, Kaushik G, Diop SB, Ding Y, Bisharat-Kernizan J, Catan H, Cammarato A, Ross RS, Engler AJ, Bodmer R, Hansen M, Ocorr K. A dual role for integrin-linked kinase and ß1-integrin in modulating cardiac aging. Aging Cell. 2014 Jun; 13(3):431-40. PMID: 24400780.
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      30. Melkani GC, Trujillo AS, Ramos R, Bodmer R, Bernstein SI, Ocorr K. Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart. PLoS Genet. 2013; 9(12):e1004024. PMID: 24367279; PMCID: PMC3868535.
      31. Tang M, Yuan W, Bodmer R, Wu X, Ocorr K. The role of pygopus in the differentiation of intracardiac valves in Drosophila. Genesis. 2014 Jan; 52(1):19-28. PMID: 24265259; PMCID: PMC4142678.
      32. Taghli-Lamallem O, Jagla K, Chamberlain JS, Bodmer R. Mechanical and non-mechanical functions of Dystrophin can prevent cardiac abnormalities in Drosophila. Exp Gerontol. 2014 Jan; 49:26-34. PMID: 24231130; PMCID: PMC4340692.
      33. Heinrichsen ET, Zhang H, Robinson JE, Ngo J, Diop S, Bodmer R, Joiner WJ, Metallo CM, Haddad GG. Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster. Mol Metab. 2014 Feb; 3(1):42-54. PMID: 24567903.
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      34. Tang M, Yuan W, Fan X, Liu M, Bodmer R, Ocorr K, Wu X. Pygopus maintains heart function in aging Drosophila independently of canonical Wnt signaling. Circ Cardiovasc Genet. 2013 Oct; 6(5):472-80. PMID: 24046329; PMCID: PMC3871875.
      35. Harpaz N, Ordan E, Ocorr K, Bodmer R, Volk T. Multiplexin promotes heart but not aorta morphogenesis by polarized enhancement of slit/robo activity at the heart lumen. PLoS Genet. 2013 Jun; 9(6):e1003597. PMID: 23825967; PMCID: PMC3694841.
      36. Nirala NK, Rahman M, Walls SM, Singh A, Zhu LJ, Bamba T, Fukusaki E, Srideshikan SM, Harris GL, Ip YT, Bodmer R, Acharya UR. Survival response to increased ceramide involves metabolic adaptation through novel regulators of glycolysis and lipolysis. PLoS Genet. 2013 Jun; 9(6):e1003556. PMID: 23818862; PMCID: PMC3688504.
      37. Dubchak I, Munoz M, Poliakov A, Salomonis N, Minovitsky S, Bodmer R, Zambon AC. Whole-Genome rVISTA: a tool to determine enrichment of transcription factor binding sites in gene promoters from transcriptomic data. Bioinformatics. 2013 Aug 15; 29(16):2059-61. PMID: 23736530.
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      38. Rahman MM, Sykiotis GP, Nishimura M, Bodmer R, Bohmann D. Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes. Aging Cell. 2013 Aug; 12(4):554-62. PMID: 23521918; PMCID: PMC3714369.
      39. Zhang Z, Hsieh B, Poe A, Anderson J, Ocorr K, Gibson G, Bodmer R. Complex genetic architecture of cardiac disease in a wild type inbred strain of Drosophila melanogaster. PLoS One. 2013; 8(4):e62909. PMID: 23638165; PMCID: PMC3639251.
      40. Na J, Musselman LP, Pendse J, Baranski TJ, Bodmer R, Ocorr K, Cagan R. A Drosophila model of high sugar diet-induced cardiomyopathy. PLoS Genet. 2013; 9(1):e1003175. PMID: 23326243; PMCID: PMC3542070.
      41. Scimia MC, Hurtado C, Ray S, Metzler S, Wei K, Wang J, Woods CE, Purcell NH, Catalucci D, Akasaka T, Bueno OF, Vlasuk GP, Kaliman P, Bodmer R, Smith LH, Ashley E, Mercola M, Brown JH, Ruiz-Lozano P. APJ acts as a dual receptor in cardiac hypertrophy. Nature. 2012 Aug 16; 488(7411):394-8. PMID: 22810587.
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      42. Kaushik G, Zambon AC, Fuhrmann A, Bernstein SI, Bodmer R, Engler AJ, Cammarato A. Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction. J Cell Mol Med. 2012 Aug; 16(8):1656-62. PMID: 22225769.
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      43. Spindler SR, Li R, Dhahbi JM, Yamakawa A, Mote P, Bodmer R, Ocorr K, Williams RT, Wang Y, Ablao KP. Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation. PLoS One. 2012; 7(6):e39581. PMID: 22737247; PMCID: PMC3380867.
      44. Qian L, Bodmer R. Probing the polygenic basis of cardiomyopathies in Drosophila. J Cell Mol Med. 2012 May; 16(5):972-7. PMID: 22268758; PMCID: PMC3337951.
      45. Diop SB, Bodmer R. Drosophila as a model to study the genetic mechanisms of obesity-associated heart dysfunction. J Cell Mol Med. 2012 May; 16(5):966-71. PMID: 22303936; PMCID: PMC3454526.
      46. Choo YS, Vogler G, Wang D, Kalvakuri S, Iliuk A, Tao WA, Bodmer R, Zhang Z. Regulation of parkin and PINK1 by neddylation. Hum Mol Genet. 2012 Jun 01; 21(11):2514-23. PMID: 22388932; PMCID: PMC3349425.
      47. Grossman TR, Gamliel A, Wessells RJ, Taghli-Lamallem O, Jepsen K, Ocorr K, Korenberg JR, Peterson KL, Rosenfeld MG, Bodmer R, Bier E. Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects. PLoS Genet. 2011 Nov; 7(11):e1002344. PMID: 22072978.
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      48. Birse RT, Bodmer R. Lipotoxicity and cardiac dysfunction in mammals and Drosophila. Crit Rev Biochem Mol Biol. 2011 Oct; 46(5):376-85. PMID: 21851295; PMCID: PMC4386717.
      49. Melkani GC, Bodmer R, Ocorr K, Bernstein SI. The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model. PLoS One. 2011; 6(7):e22579. PMID: 21799905; PMCID: PMC3143160.
      50. Lim HY, Bodmer R. Phospholipid homeostasis and lipotoxic cardiomyopathy: a matter of balance. Fly (Austin). 2011 Jul-Sep; 5(3):234-6. PMID: 21494094; PMCID: PMC3225766.
      51. Eleftherianos I, Won S, Chtarbanova S, Squiban B, Ocorr K, Bodmer R, Beutler B, Hoffmann JA, Imler JL. ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):12024-9. PMID: 21719711; PMCID: PMC3141999.
      52. Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, Otway RT, Huang Y, King IN, Maillet M, Zheng Y, Crawley T, Taghli-Lamallem O, Semsarian C, Dunwoodie S, Winlaw D, Harvey RP, Fatkin D, Towbin JA, Molkentin JD, Srivastava D, Ocorr K, Bruneau BG, Bodmer R. Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. J Cell Biol. 2011 Jun 27; 193(7):1181-96. PMID: 21690310; PMCID: PMC3216339.
      53. Cammarato A, Ahrens CH, Alayari NN, Qeli E, Rucker J, Reedy MC, Zmasek CM, Gucek M, Cole RN, Van Eyk JE, Bodmer R, O'Rourke B, Bernstein SI, Foster DB. A mighty small heart: the cardiac proteome of adult Drosophila melanogaster. PLoS One. 2011 Apr 25; 6(4):e18497. PMID: 21541028; PMCID: PMC3081823.
      54. Lim HY, Wang W, Wessells RJ, Ocorr K, Bodmer R. Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila. Genes Dev. 2011 Jan 15; 25(2):189-200. PMID: 21245170; PMCID: PMC3022264.
      55. Nishimura M, Ocorr K, Bodmer R, Cartry J. Drosophila as a model to study cardiac aging. Exp Gerontol. 2011 May; 46(5):326-30. PMID: 21130861; PMCID: PMC3079765.
      56. Birse RT, Choi J, Reardon K, Rodriguez J, Graham S, Diop S, Ocorr K, Bodmer R, Oldham S. High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila. Cell Metab. 2010 Nov 03; 12(5):533-44. PMID: 21035763; PMCID: PMC3026640.
      57. Lee JH, Bodmer R, Bier E, Karin M. Sestrins at the crossroad between stress and aging. Aging (Albany NY). 2010 Jun; 2(6):369-74. PMID: 20606249.
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      58. Luo N, Li G, Li Y, Fan X, Wang Y, Ye X, Mo X, Zhou J, Yuan W, Tan M, Xie H, Ocorr K, Bodmer R, Deng Y, Wu X. SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity. BMB Rep. 2010 May; 43(5):355-61. PMID: 20510020.
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      59. Neely GG, Kuba K, Cammarato A, Isobe K, Amann S, Zhang L, Murata M, Elmén L, Gupta V, Arora S, Sarangi R, Dan D, Fujisawa S, Usami T, Xia CP, Keene AC, Alayari NN, Yamakawa H, Elling U, Berger C, Novatchkova M, Koglgruber R, Fukuda K, Nishina H, Isobe M, Pospisilik JA, Imai Y, Pfeufer A, Hicks AA, Pramstaller PP, Subramaniam S, Kimura A, Ocorr K, Bodmer R, Penninger JM. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Cell. 2010 Apr 02; 141(1):142-53. PMID: 20371351; PMCID: PMC2855221.
      60. Lee JH, Budanov AV, Park EJ, Birse R, Kim TE, Perkins GA, Ocorr K, Ellisman MH, Bodmer R, Bier E, Karin M. Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies. Science. 2010 Mar 5; 327(5970):1223-8. PMID: 20203043.
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      61. Hu J, Yuan W, Tang M, Wang Y, Fan X, Mo X, Li Y, Ying Z, Wan Y, Ocorr K, Bodmer R, Deng Y, Wu X. KBTBD7, a novel human BTB-kelch protein, activates transcriptional activities of SRE and AP-1. BMB Rep. 2010 Jan; 43(1):17-22. PMID: 20132730.
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      62. Alayari NN, Vogler G, Taghli-Lamallem O, Ocorr K, Bodmer R, Cammarato A. Fluorescent labeling of Drosophila heart structures. J Vis Exp. 2009 Oct 13; (32). PMID: 19826399; PMCID: PMC3164059.
      63. Ocorr K, Fink M, Cammarato A, Bernstein S, Bodmer R. Semi-automated Optical Heartbeat Analysis of small hearts. J Vis Exp. 2009 Sep 16; (31). PMID: 19759521; PMCID: PMC3150057.
      64. Wessells R, Fitzgerald E, Piazza N, Ocorr K, Morley S, Davies C, Lim HY, Elmén L, Hayes M, Oldham S, Bodmer R. d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila. Aging Cell. 2009 Sep; 8(5):542-52. PMID: 19594484; PMCID: PMC2832479.
      65. Qian L, Bodmer R. Partial loss of GATA factor Pannier impairs adult heart function in Drosophila. Hum Mol Genet. 2009 Sep 01; 18(17):3153-63. PMID: 19494035; PMCID: PMC2722980.
      66. Buechling T, Akasaka T, Vogler G, Ruiz-Lozano P, Ocorr K, Bodmer R. Non-autonomous modulation of heart rhythm, contractility and morphology in adult fruit flies. Dev Biol. 2009 Apr 15; 328(2):483-92. PMID: 19233157; PMCID: PMC2829972.
      67. Fink M, Callol-Massot C, Chu A, Ruiz-Lozano P, Izpisua Belmonte JC, Giles W, Bodmer R, Ocorr K. A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts. Biotechniques. 2009 Feb; 46(2):101-13. PMID: 19317655.
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      68. Mann T, Bodmer R, Pandur P. The Drosophila homolog of vertebrate Islet1 is a key component in early cardiogenesis. Development. 2009 Jan; 136(2):317-26. PMID: 19088091; PMCID: PMC2685972.
      69. Qian L, Mohapatra B, Akasaka T, Liu J, Ocorr K, Towbin JA, Bodmer R. Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease. Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50):19833-8. PMID: 19074289; PMCID: PMC2605007.
      70. Yu W, Li Y, Zhou X, Deng Y, Wang Z, Yuan W, Li D, Zhu C, Zhao X, Mo X, Huang W, Luo N, Yan Y, Ocorr K, Bodmer R, Wang Y, Wu X. A novel human BTB-kelch protein KLHL31, strongly expressed in muscle and heart, inhibits transcriptional activities of TRE and SRE. Mol Cells. 2008 Nov 30; 26(5):443-53. PMID: 18719355.
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      71. Wang D, Tang B, Zhao G, Pan Q, Xia K, Bodmer R, Zhang Z. Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons. Mol Neurodegener. 2008 Feb 08; 3:3. PMID: 18257932; PMCID: PMC2276501.
      72. Taghli-Lamallem O, Akasaka T, Hogg G, Nudel U, Yaffe D, Chamberlain JS, Ocorr K, Bodmer R. Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype. Aging Cell. 2008 Mar; 7(2):237-49. PMID: 18221418; PMCID: PMC2840698.
      73. Mery A, Taghli-Lamallem O, Clark KA, Beckerle MC, Wu X, Ocorr K, Bodmer R. The Drosophila muscle LIM protein, Mlp84B, is essential for cardiac function. J Exp Biol. 2008 Jan; 211(Pt 1):15-23. PMID: 18083727.
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      74. Li Y, Yang D, Bai Y, Mo X, Huang W, Yuan W, Yin Z, Deng Y, Murashko O, Wang Y, Fan X, Zhu C, Ocorr K, Bodmer R, Wu X. ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway. Mol Cell Biochem. 2008 Mar; 310(1-2):141-51. PMID: 18084723.
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      75. Shaw P, Ocorr K, Bodmer R, Oldham S. Drosophila aging 2006/2007. Exp Gerontol. 2008 Jan; 43(1):5-10. PMID: 18061385; PMCID: PMC2223272.
      76. Cammarato A, Dambacher CM, Knowles AF, Kronert WA, Bodmer R, Ocorr K, Bernstein SI. Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles. Mol Biol Cell. 2008 Feb; 19(2):553-62. PMID: 18045988; PMCID: PMC2230588.
      77. Liu J, Qian L, Han Z, Wu X, Bodmer R. Spatial specificity of mesodermal even-skipped expression relies on multiple repressor sites. Dev Biol. 2008 Jan 15; 313(2):876-86. PMID: 18067885; PMCID: PMC2245897.
      78. Ocorr KA, Crawley T, Gibson G, Bodmer R. Genetic variation for cardiac dysfunction in Drosophila. PLoS One. 2007 Jul 11; 2(7):e601. PMID: 17622346; PMCID: PMC1913553.
      79. Ocorr K, Perrin L, Lim HY, Qian L, Wu X, Bodmer R. Genetic control of heart function and aging in Drosophila. Trends Cardiovasc Med. 2007 Jul; 17(5):177-82. PMID: 17574126; PMCID: PMC1950717.
      80. Ocorr K, Reeves NL, Wessells RJ, Fink M, Chen HS, Akasaka T, Yasuda S, Metzger JM, Giles W, Posakony JW, Bodmer R. KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging. Proc Natl Acad Sci U S A. 2007 Mar 6; 104(10):3943-8. PMID: 17360457.
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      81. Wessells RJ, Bodmer R. Age-related cardiac deterioration: insights from Drosophila. Front Biosci. 2007 Jan 01; 12:39-48. PMID: 17127282.
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      82. Wessells RJ, Bodmer R. Cardiac aging. Semin Cell Dev Biol. 2007 Feb; 18(1):111-6. PMID: 17275368.
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      83. Lim HY, Bodmer R, Perrin L. Drosophila aging 2005/06. Exp Gerontol. 2006 Dec; 41(12):1213-6. PMID: 17126511; PMCID: PMC1855203.
      84. Ocorr K, Akasaka T, Bodmer R. Age-related cardiac disease model of Drosophila. Mech Ageing Dev. 2007 Jan; 128(1):112-6. PMID: 17125816; PMCID: PMC1850850.
      85. Zaffran S, Reim I, Qian L, Lo PC, Bodmer R, Frasch M. Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila. Development. 2006 Oct; 133(20):4073-83. PMID: 16987868.
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      86. Liu M, Su M, Lyons GE, Bodmer R. Functional conservation of zinc-finger homeodomain gene zfh1/SIP1 in Drosophila heart development. Dev Genes Evol. 2006 Nov; 216(11):683-93. PMID: 16957952.
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      87. Wang D, Qian L, Xiong H, Liu J, Neckameyer WS, Oldham S, Xia K, Wang J, Bodmer R, Zhang Z. Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila. Proc Natl Acad Sci U S A. 2006 Sep 05; 103(36):13520-5. PMID: 16938835; PMCID: PMC1569195.
      88. Akasaka T, Klinedinst S, Ocorr K, Bustamante EL, Kim SK, Bodmer R. The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):11999-2004. PMID: 16882722; PMCID: PMC1567687.
      89. Luong N, Davies CR, Wessells RJ, Graham SM, King MT, Veech R, Bodmer R, Oldham SM. Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity. Cell Metab. 2006 Aug; 4(2):133-42. PMID: 16890541.
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      90. Choma MA, Izatt SD, Wessells RJ, Bodmer R, Izatt JA. Images in cardiovascular medicine: in vivo imaging of the adult Drosophila melanogaster heart with real-time optical coherence tomography. Circulation. 2006 Jul 11; 114(2):e35-6. PMID: 16831991.
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      91. Liu J, Qian L, Wessells RJ, Bidet Y, Jagla K, Bodmer R. Hedgehog and RAS pathways cooperate in the anterior-posterior specification and positioning of cardiac progenitor cells. Dev Biol. 2006 Feb 15; 290(2):373-85. PMID: 16387294.
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      92. Qian L, Liu J, Bodmer R. Slit and Robo control cardiac cell polarity and morphogenesis. Curr Biol. 2005 Dec 20; 15(24):2271-8. PMID: 16360689.
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      93. Fujioka M, Wessells RJ, Han Z, Liu J, Fitzgerald K, Yusibova GL, Zamora M, Ruiz-Lozano P, Bodmer R, Jaynes JB. Embryonic even skipped-dependent muscle and heart cell fates are required for normal adult activity, heart function, and lifespan. Circ Res. 2005 Nov 25; 97(11):1108-14. PMID: 16239588; PMCID: PMC2726805.
      94. Krupp JJ, Yaich LE, Wessells RJ, Bodmer R. Identification of genetic loci that interact with cut during Drosophila wing-margin development. Genetics. 2005 Aug; 170(4):1775-95. PMID: 15956666; PMCID: PMC1449764.
      95. Qian L, Liu J, Bodmer R. Neuromancer Tbx20-related genes (H15/midline) promote cell fate specification and morphogenesis of the Drosophila heart. Dev Biol. 2005 Mar 15; 279(2):509-24. PMID: 15733676.
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      96. Wessells RJ, Fitzgerald E, Cypser JR, Tatar M, Bodmer R. Insulin regulation of heart function in aging fruit flies. Nat Genet. 2004 Dec; 36(12):1275-81. PMID: 15565107.
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      97. Bier E, Bodmer R. Drosophila, an emerging model for cardiac disease. Gene. 2004 Nov 10; 342(1):1-11. PMID: 15527959.
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      98. Zimmer C, Tiveron MC, Bodmer R, Cremer H. Dynamics of Cux2 expression suggests that an early pool of SVZ precursors is fated to become upper cortical layer neurons. Cereb Cortex. 2004 Dec; 14(12):1408-20. PMID: 15238450.
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      99. Wessells RJ, Bodmer R. Screening assays for heart function mutants in Drosophila. Biotechniques. 2004 Jul; 37(1):58-60, 62, 64 passim. PMID: 15283201.
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      100. Klinedinst SL, Bodmer R. Gata factor Pannier is required to establish competence for heart progenitor formation. Development. 2003 Jul; 130(13):3027-38. PMID: 12756184.
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      101. Han Z, Bodmer R. Myogenic cells fates are antagonized by Notch only in asymmetric lineages of the Drosophila heart, with or without cell division. Development. 2003 Jul; 130(13):3039-51. PMID: 12756185.
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      102. Holland ND, Venkatesh TV, Holland LZ, Jacobs DK, Bodmer R. AmphiNk2-tin, an amphioxus homeobox gene expressed in myocardial progenitors: insights into evolution of the vertebrate heart. Dev Biol. 2003 Mar 1; 255(1):128-37. PMID: 12618138.
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      103. Han Z, Fujioka M, Su M, Liu M, Jaynes JB, Bodmer R. Transcriptional integration of competence modulated by mutual repression generates cell-type specificity within the cardiogenic mesoderm. Dev Biol. 2002 Dec 15; 252(2):225-40. PMID: 12482712; PMCID: PMC2693947.
      104. Akasaka T, Takahashi N, Suzuki M, Koseki H, Bodmer R, Koga H. MBLR, a new RING finger protein resembling mammalian Polycomb gene products, is regulated by cell cycle-dependent phosphorylation. Genes Cells. 2002 Aug; 7(8):835-50. PMID: 12167161.
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      105. Lockwood WK, Bodmer R. The patterns of wingless, decapentaplegic, and tinman position the Drosophila heart. Mech Dev. 2002 Jun; 114(1-2):13-26. PMID: 12175486.
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      106. Hardiman KE, Brewster R, Khan SM, Deo M, Bodmer R. The bereft gene, a potential target of the neural selector gene cut, contributes to bristle morphogenesis. Genetics. 2002 May; 161(1):231-47. PMID: 12019237; PMCID: PMC1462110.
      107. Yuan WZ, Bodmer R, Zhu CB, Wang YQ, Li YQ, Wu XS. [The use of RNAi as a technique to study the functions of heart-related genes in Drosophila]. Yi Chuan Xue Bao. 2002 Jan; 29(1):34-8. PMID: 11838373.
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