Dr. Schwab's research focuses on biomarkers to diagnosis and refine the treatment of cancer. His current projects include precision oncology using DNA sequencing, target discovery using RNA sequencing, and validation of novel cancer initiating cell markers.
In support of these, and future, biomarker studies Dr. Schwab co-directs a biorepository to prospectively collect de-identified blood, urine and tumor specimens. This resource has a series of key features to maximize its future utility; (1) specimens are associated with detailed clinical data that is regularly updated, (2) three methods to ensure follow up data are available are used, including social security number queries to the national databases, (3) samples are stored as small volume aliquots at –80 degrees Celsius to prevent freeze/thaw damage, (4) subjects are consented for germ line DNA sequencing (5) buffy coat is stored in nucleic acid stabilizing solution and (6) through a collaboration with The Jackson Laboratory patient derived xenografts are generated.
Education and Training
BA - Molecular and Cell Biology, University of California, Berkeley - 1995
MD - Albert Einstein College of Medicine - 2000
Residency - Internal Medicine, University of California, San Diego - 2003
Fellowship - Hematology/Oncology, University of California, San Diego - 2006