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Raphael Reher

Title(s)Postdoctoral Scholar, Center for Marine Biotechnology and Biomedecine
SchoolMarine Sciences
Address9500 Gilman Drive #0212
La Jolla CA 92093
Phone858-534-0578
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Products. J Am Chem Soc. 2020 Mar 04; 142(9):4114-4120. Reher R, Kim HW, Zhang C, Mao HH, Wang M, Nothias LF, Caraballo-Rodriguez AM, Glukhov E, Teke B, Leao T, Alexander KL, Duggan BM, Van Everbroeck EL, Dorrestein PC, Cottrell GW, Gerwick WH. PMID: 32045230.
      View in: PubMed   Mentions: 2     Fields:    
    2. Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors. Br J Pharmacol. 2020 Apr; 177(8):1898-1916. Kuschak M, Namasivayam V, Rafehi M, Voss JH, Garg J, Schlegel JG, Abdelrahman A, Kehraus S, Reher R, Küppers J, Sylvester K, Hinz S, Matthey M, Wenzel D, Fleischmann BK, Pfeifer A, Inoue A, Gütschow M, König GM, Müller CE. PMID: 31881095.
      View in: PubMed   Mentions:    Fields:    
    3. Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain. J Med Chem. 2019 10 24; 62(20):9026-9044. Boudreau PD, Miller BW, McCall LI, Almaliti J, Reher R, Hirata K, Le T, Siqueira-Neto JL, Hook V, Gerwick WH. PMID: 31539239.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    4. Structural and Dynamical Basis of G Protein Inhibition by YM-254890 and FR900359: An Inhibitor in Action. J Chem Inf Model. 2019 10 28; 59(10):4361-4373. Tietze D, Kaufmann D, Tietze AA, Voll A, Reher R, König G, Hausch F. PMID: 31539242.
      View in: PubMed   Mentions:    Fields:    
    5. Direct targeting of Gaq and Ga11 oncoproteins in cancer cells. Sci Signal. 2019 03 19; 12(573). Annala S, Feng X, Shridhar N, Eryilmaz F, Patt J, Yang J, Pfeil EM, Cervantes-Villagrana RD, Inoue A, Häberlein F, Slodczyk T, Reher R, Kehraus S, Monteleone S, Schrage R, Heycke N, Rick U, Engel S, Pfeifer A, Kolb P, König G, Bünemann M, Tüting T, Vázquez-Prado J, Gutkind JS, Gaffal E, Kostenis E. PMID: 30890659.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. Rational design of a heterotrimeric G protein a subunit with artificial inhibitor sensitivity. J Biol Chem. 2019 04 12; 294(15):5747-5758. Malfacini D, Patt J, Annala S, Harpsøe K, Eryilmaz F, Reher R, Crüsemann M, Hanke W, Zhang H, Tietze D, Gloriam DE, Bräuner-Osborne H, Strømgaard K, König GM, Inoue A, Gomeza J, Kostenis E. PMID: 30745359.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Deciphering Specificity Determinants for FR900359-Derived Gq a Inhibitors Based on Computational and Structure-Activity Studies. ChemMedChem. 2018 08 20; 13(16):1634-1643. Reher R, Kühl T, Annala S, Benkel T, Kaufmann D, Nubbemeyer B, Odhiambo JP, Heimer P, Bäuml CA, Kehraus S, Crüsemann M, Kostenis E, Tietze D, König GM, Imhof D. PMID: 29873888.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    8. Applying Molecular Networking for the Detection of Natural Sources and Analogues of the Selective Gq Protein Inhibitor FR900359. J Nat Prod. 2018 07 27; 81(7):1628-1635. Reher R, Kuschak M, Heycke N, Annala S, Kehraus S, Dai HF, Müller CE, Kostenis E, König GM, Crüsemann M. PMID: 29943987.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    9. Lack of beta-arrestin signaling in the absence of active G proteins. Nat Commun. 2018 01 23; 9(1):341. Grundmann M, Merten N, Malfacini D, Inoue A, Preis P, Simon K, Rüttiger N, Ziegler N, Benkel T, Schmitt NK, Ishida S, Müller I, Reher R, Kawakami K, Inoue A, Rick U, Kühl T, Imhof D, Aoki J, König GM, Hoffmann C, Gomeza J, Wess J, Kostenis E. PMID: 29362459.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    10. Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359. Angew Chem Int Ed Engl. 2018 01 15; 57(3):836-840. Crüsemann M, Reher R, Schamari I, Brachmann AO, Ohbayashi T, Kuschak M, Malfacini D, Seidinger A, Pinto-Carbó M, Richarz R, Reuter T, Kehraus S, Hallab A, Attwood M, Schiöth HB, Mergaert P, Kikuchi Y, Schäberle TF, Kostenis E, Wenzel D, Müller CE, Piel J, Carlier A, Eberl L, König GM. PMID: 29194875.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    11. The genome analysis of Candidatus Burkholderia crenata reveals that secondary metabolism may be a key function of the Ardisia crenata leaf nodule symbiosis. Environ Microbiol. 2016 09; 18(8):2507-22. Carlier A, Fehr L, Pinto-Carbó M, Schäberle T, Reher R, Dessein S, König G, Eberl L. PMID: 26663534.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells