Philipp Spahn

TitlePostdoctoral Scholar
InstitutionUniversity of California San Diego
Address9500 Gilman Drive #0760
La Jolla CA 92093
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    1. Spahn PN, Bath T, Weiss RJ, Kim J, Esko JD, Lewis NE, Harismendy O. PinAPL-Py: A comprehensive web-application for the analysis of CRISPR/Cas9 screens. Sci Rep. 2017 Nov 20; 7(1):15854. PMID: 29158538.
      View in: PubMed
    2. Spahn PN, Hansen AH, Kol S, Voldborg BG, Lewis NE. Predictive glycoengineering of biosimilars using a Markov chain glycosylation model. Biotechnol J. 2017 Feb; 12(2). PMID: 27860290.
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    3. Hefzi H, Ang KS, Hanscho M, Bordbar A, Ruckerbauer D, Lakshmanan M, Orellana CA, Baycin-Hizal D, Huang Y, Ley D, Martinez VS, Kyriakopoulos S, Jiménez NE, Zielinski DC, Quek LE, Wulff T, Arnsdorf J, Li S, Lee JS, Paglia G, Loira N, Spahn PN, Pedersen LE, Gutierrez JM, King ZA, Lund AM, Nagarajan H, Thomas A, Abdel-Haleem AM, Zanghellini J, Kildegaard HF, Voldborg BG, Gerdtzen ZP, Betenbaugh MJ, Palsson BO, Andersen MR, Nielsen LK, Borth N, Lee DY, Lewis NE. A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism. Cell Syst. 2016 Nov 23; 3(5):434-443.e8. PMID: 27883890.
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    4. Chiang AW, Li S, Spahn PN, Richelle A, Kuo CC, Samoudi M, Lewis NE. Modulating carbohydrate-protein interactions through glycoengineering of monoclonal antibodies to impact cancer physiology. Curr Opin Struct Biol. 2016 10; 40:104-111. PMID: 27639240.
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    5. Spahn PN, Hansen AH, Hansen HG, Arnsdorf J, Kildegaard HF, Lewis NE. A Markov chain model for N-linked protein glycosylation--towards a low-parameter tool for model-driven glycoengineering. Metab Eng. 2016 Jan; 33:52-66. PMID: 26537759.
      View in: PubMed
    6. Spahn PN, Lewis NE. Systems glycobiology for glycoengineering. Curr Opin Biotechnol. 2014 Dec; 30:218-24. PMID: 25202878.
      View in: PubMed
    7. Spahn P, Huelsmann S, Rehorn KP, Mischke S, Mayer M, Casali A, Reuter R. Multiple regulatory safeguards confine the expression of the GATA factor Serpent to the hemocyte primordium within the Drosophila mesoderm. Dev Biol. 2014 Feb 01; 386(1):272-9. PMID: 24360907.
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    8. Boehme P, Spahn P, Amendt J, Zehner R. The analysis of temporal gene expression to estimate the age of forensically important blow fly pupae: results from three blind studies. Int J Legal Med. 2014 May; 128(3):565-73. PMID: 24178670.
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    9. Spahn P, Reuter R. A vertex model of Drosophila ventral furrow formation. PLoS One. 2013; 8(9):e75051. PMID: 24066163; PMCID: PMC3774731.
    10. Boehme P, Spahn P, Amendt J, Zehner R. Differential gene expression during metamorphosis: a promising approach for age estimation of forensically important Calliphora vicina pupae (Diptera: Calliphoridae). Int J Legal Med. 2013 Jan; 127(1):243-9. PMID: 22555870.
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    11. Spahn P, Ott A, Reuter R. The PDZ-GEF protein Dizzy regulates the establishment of adherens junctions required for ventral furrow formation in Drosophila. J Cell Sci. 2012 Aug 15; 125(Pt 16):3801-12. PMID: 22553205.
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    12. Garnica S, Spahn P, Oertel B, Ammirati J, Oberwinkler F. Tracking the evolutionary history of Cortinarius species in section Calochroi, with transoceanic disjunct distributions. BMC Evol Biol. 2011 Jul 19; 11:213. PMID: 21771336; PMCID: PMC3161008.
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