Philipp Spahn

Title(s)	Assistant Project Scientist, Pediatrics
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate. Nat Chem Biol. 2021 06; 17(6):684-692. Weiss RJ, Spahn PN, Chiang AWT, Liu Q, Li J, Hamill KM, Rother S, Clausen TM, Hoeksema MA, Timm BM, Godula K, Glass CK, Tor Y, Gordts PLSM, Lewis NE, Esko JD. PMID: 33846619.

View in: PubMed Mentions: 1 Fields:
Bio Biology Che Chemistry
Translation:Humans Cells
A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes. Metab Eng. 2021 07; 66:114-122. Karottki KJC, Hefzi H, Li S, Pedersen LE, Spahn PN, Joshi C, Ruckerbauer D, Bort JAH, Thomas A, Lee JS, Borth N, Lee GM, Kildegaard HF, Lewis NE. PMID: 33813034.

View in: PubMed Mentions: 1 Fields:
Bio Biomedical Engineering Met Metabolism
ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis. Proc Natl Acad Sci U S A. 2020 04 28; 117(17):9311-9317. Weiss RJ, Spahn PN, Toledo AG, Chiang AWT, Kellman BP, Li J, Benner C, Glass CK, Gordts PLSM, Lewis NE, Esko JD. PMID: 32277030.

View in: PubMed Mentions: 5 Fields:
Sci Science
Translation:Humans Animals Cells
A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma. Cell. 2019 04 18; 177(3):572-586.e22. Lytle NK, Ferguson LP, Rajbhandari N, Gilroy K, Fox RG, Deshpande A, Schürch CM, Hamilton M, Robertson N, Lin W, Noel P, Wartenberg M, Zlobec I, Eichmann M, Galván JA, Karamitopoulou E, Gilderman T, Esparza LA, Shima Y, Spahn P, French R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik M, Von Hoff D, Han H, Ideker T, Deshpande AJ, Lowy AM, Adams PD, Reya T. PMID: 30955884.

View in: PubMed Mentions: 27 Fields:
Cel Cell Biology
Translation:Humans Animals Cells
PinAPL-Py: A comprehensive web-application for the analysis of CRISPR/Cas9 screens. Sci Rep. 2017 Nov 20; 7(1):15854. Spahn PN, Bath T, Weiss RJ, Kim J, Esko JD, Lewis NE, Harismendy O. PMID: 29158538.

View in: PubMed Mentions: 13 Fields:
Sci Science
Predictive glycoengineering of biosimilars using a Markov chain glycosylation model. Biotechnol J. 2017 Feb; 12(2). Spahn PN, Hansen AH, Kol S, Voldborg BG, Lewis NE. PMID: 27860290.

View in: PubMed Mentions: 8 Fields:
Bio Biotechnology
Translation:Animals Cells
A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism. Cell Syst. 2016 11 23; 3(5):434-443.e8. Hefzi H, Ang KS, Hanscho M, Bordbar A, Ruckerbauer D, Lakshmanan M, Orellana CA, Baycin-Hizal D, Huang Y, Ley D, Martinez VS, Kyriakopoulos S, Jiménez NE, Zielinski DC, Quek LE, Wulff T, Arnsdorf J, Li S, Lee JS, Paglia G, Loira N, Spahn PN, Pedersen LE, Gutierrez JM, King ZA, Lund AM, Nagarajan H, Thomas A, Abdel-Haleem AM, Zanghellini J, Kildegaard HF, Voldborg BG, Gerdtzen ZP, Betenbaugh MJ, Palsson BO, Andersen MR, Nielsen LK, Borth N, Lee DY, Lewis NE. PMID: 27883890.

View in: PubMed Mentions: 34 Fields:
Cel Cell Biology Com Computational Biology Mol Molecular Biology
Translation:Humans Animals Cells
Modulating carbohydrate-protein interactions through glycoengineering of monoclonal antibodies to impact cancer physiology. Curr Opin Struct Biol. 2016 10; 40:104-111. Chiang AW, Li S, Spahn PN, Richelle A, Kuo CC, Samoudi M, Lewis NE. PMID: 27639240.

View in: PubMed Mentions: 8 Fields:
Bio Biochemistry Mol Molecular Biology
Translation:Humans Animals
A Markov chain model for N-linked protein glycosylation--towards a low-parameter tool for model-driven glycoengineering. . 2016 Jan; 33:52-66. Spahn PN, Hansen AH, Hansen HG, Arnsdorf J, Kildegaard HF, Lewis NE. PMID: 26537759.

View in: PubMed Mentions:
Systems glycobiology for glycoengineering. Curr Opin Biotechnol. 2014 Dec; 30:218-24. Spahn PN, Lewis NE. PMID: 25202878.

View in: PubMed Mentions: 20 Fields:
Bio Biotechnology
Translation:Humans Cells
Multiple regulatory safeguards confine the expression of the GATA factor Serpent to the hemocyte primordium within the Drosophila mesoderm. Dev Biol. 2014 Feb 01; 386(1):272-9. Spahn P, Huelsmann S, Rehorn KP, Mischke S, Mayer M, Casali A, Reuter R. PMID: 24360907.

View in: PubMed Mentions: 1 Fields:
Bio Biology Emb Embryology
Translation:Animals Cells
The analysis of temporal gene expression to estimate the age of forensically important blow fly pupae: results from three blind studies. Int J Legal Med. 2014 May; 128(3):565-73. Boehme P, Spahn P, Amendt J, Zehner R. PMID: 24178670.

View in: PubMed Mentions: 8 Fields:
Jur Jurisprudence
Translation:Animals
A vertex model of Drosophila ventral furrow formation. PLoS One. 2013; 8(9):e75051. Spahn P, Reuter R. PMID: 24066163.

View in: PubMed Mentions: 18 Fields:
Med Medicine (General)Sci Science
Translation:Animals
Differential gene expression during metamorphosis: a promising approach for age estimation of forensically important Calliphora vicina pupae (Diptera: Calliphoridae). Int J Legal Med. 2013 Jan; 127(1):243-9. Boehme P, Spahn P, Amendt J, Zehner R. PMID: 22555870.

View in: PubMed Mentions: 13 Fields:
Jur Jurisprudence
Translation:Animals
The PDZ-GEF protein Dizzy regulates the establishment of adherens junctions required for ventral furrow formation in Drosophila. J Cell Sci. 2012 Aug 15; 125(Pt 16):3801-12. Spahn P, Ott A, Reuter R. PMID: 22553205.

View in: PubMed Mentions: 14 Fields:
Cel Cell Biology
Translation:Animals Cells
Tracking the evolutionary history of Cortinarius species in section Calochroi, with transoceanic disjunct distributions. BMC Evol Biol. 2011 Jul 19; 11:213. Garnica S, Spahn P, Oertel B, Ammirati J, Oberwinkler F. PMID: 21771336.

View in: PubMed Mentions: 5 Fields:
Bio Biology
Translation:Animals Cells