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Owen Leddy

Title(s)Postdoctoral Scholar, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Correction: Immunopeptidomics reveals determinants of Mycobacterium tuberculosis antigen presentation on MHC class I. Elife. 2025 Aug 20; 14. Leddy O, White FM, Bryson BD. PMID: 40833258; PMCID: PMC12367294.
      View in: PubMed   Mentions:    Fields:    
    2. Targeting infection-specific peptides in immunopeptidomics studies for vaccine target discovery. J Exp Med. 2025 Oct 06; 222(10). Leddy O, Yuki Y, Carrington M, Bryson BD, White FM. PMID: 40689854; PMCID: PMC12279011.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. High-throughput screening for class I peptide MHC binding via yeast surface display. bioRxiv. 2025 May 28. Holec PV, Breuckman KC, Leddy O, White FM, Bryson BD, Birnbaum ME. PMID: 40501710; PMCID: PMC12154660.
      View in: PubMed   Mentions:
    4. A SecA-associated protease modulates the extent of surface display of staphylococcal protein A. J Bacteriol. 2025 Apr 17; 207(4):e0052224. Azam MS, Ibrahim AM, Leddy O, Oh S-Y, Schneewind O, Missiakas D. PMID: 40135891; PMCID: PMC12004944.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    5. Screening a library of temperature-sensitive mutants to identify secretion factors in Staphylococcus aureus. J Bacteriol. 2025 Feb 20; 207(2):e0043324. Leddy O, Ibrahim AM, Azam MS, Solomon S, Yu W, Schneewind O, Missiakas D. PMID: 39817767; PMCID: PMC11841065.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    6. Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface. Microbiol Spectr. 2025 Feb 04; 13(2):e0227724. Lepe BA, Zheng CR, Leddy OK, Allsup BL, Solomon SL, Bryson BD. PMID: 39688428; PMCID: PMC11792546.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. Validation and quantification of peptide antigens presented on MHCs using SureQuant. Nat Protoc. 2025 05; 20(5):1196-1222. Leddy O, Cui Y, Ahn R, Stopfer L, Choe E, Kim DH, Roerden M, Spranger S, Bryson BD, White FM. PMID: 39438697; PMCID: PMC12012165.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. PathMHC: a workflow to selectively target pathogen-derived MHC peptides in discovery immunopeptidomics experiments for vaccine target identification. bioRxiv. 2024 Sep 11. Leddy O, Yuki Y, Carrington M, Bryson BD, White FM. PMID: 39314426; PMCID: PMC11419027.
      View in: PubMed   Mentions:
    9. Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface. bioRxiv. 2024 Jul 02. Lepe BA, Zheng CR, Leddy OK, Allsup BL, Solomon SL, Bryson BD. PMID: 39005324; PMCID: PMC11245043.
      View in: PubMed   Mentions:
    10. Immunopeptidomics reveals determinants of Mycobacterium tuberculosis antigen presentation on MHC class I. Elife. 2023 04 19; 12. Leddy O, White FM, Bryson BD. PMID: 37073954; PMCID: PMC10159623.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    11. MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas. Proc Natl Acad Sci U S A. 2022 12 06; 119(49):e2208900119. Stopfer LE, Rettko NJ, Leddy O, Mesfin JM, Brown E, Winski S, Bryson B, Wells JA, White FM. PMID: 36454758; PMCID: PMC9894220.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    12. Leveraging Immunopeptidomics To Study and Combat Infectious Disease. mSystems. 2021 Aug 31; 6(4):e0031021. Leddy OK, White FM, Bryson BD. PMID: 34342538; PMCID: PMC8407116.
      View in: PubMed   Mentions: 9     Fields:    
    13. Structured silicon for revealing transient and integrated signal transductions in microbial systems. Sci Adv. 2020 02; 6(7):eaay2760. Gao X, Jiang Y, Lin Y, Kim KH, Fang Y, Yi J, Meng L, Lee HC, Lu Z, Leddy O, Zhang R, Tu Q, Feng W, Nair V, Griffin PJ, Shi F, Shekhawat GS, Dinner AR, Park HG, Tian B. PMID: 32110728; PMCID: PMC7021504.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    14. Entropic constraints on the steady-state fitness of competing self-replicators. J Chem Phys. 2018 Dec 14; 149(22):224105. Leddy O, Lu Z, Dinner AR. PMID: 30553248; PMCID: PMC7789856.
      View in: PubMed   Mentions:    Fields:    
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