Olivier Harismendy

Title(s)Adjunct Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
vCardDownload vCard

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    FEN1 Endonuclease as a Synthetic Lethal Target for Cancer Therapy
    NIH R01CA255341Aug 15, 2021 - Jul 31, 2026
    Role: Co-Principal Investigator
    In vivo detection and genome-wide location analysis of DNA-adducts
    NIH R21CA177519Sep 3, 2013 - Aug 31, 2017
    Role: Principal Investigator
    Identification of Somatic Mutations in Rare Subclones of Solid Tumors
    NIH R21CA155615Sep 22, 2011 - Aug 31, 2013
    Role: Principal Investigator
    REGULATORY GENOMIC STUDIES IN A COHORT OF IPS CELL DERIVED CARDIOMYOCYTES
    NIH U01HL107442Jul 15, 2011 - Jun 30, 2017
    Role: Principal Investigator

    Collapse Featured Content 
    Collapse Twitter
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ-focal adhesion kinase signaling circuitry. J Biol Chem. 2022 Dec 31; 299(2):102866. Arang N, Lubrano S, Rigiracciolo DC, Nachmanson D, Lippman SM, Mali P, Harismendy O, Gutkind JS. PMID: 36596361.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Accurate genome-wide genotyping from archival tissue to explore the contribution of common genetic variants to pre-cancer outcomes. J Transl Med. 2022 12 27; 20(1):623. Nachmanson D, Pagadala M, Steward J, Cheung C, Bruce LK, Lee NQ, O'Keefe TJ, Lin GY, Hasteh F, Morris GP, Carter H, Harismendy O. PMID: 36575447; PMCID: PMC9793518.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. A Randomized Multi-institutional Phase II Trial of Everolimus as Adjuvant Therapy in Patients with Locally Advanced Squamous Cell Cancer of the Head and Neck. Clin Cancer Res. 2022 12 01; 28(23):5040-5048. Nathan CO, Hayes DN, Karrison T, Harismendy O, Flores JM, Moore-Medlin T, Vokes EE, Gutkind JS, Neupane P, Mills G, Sargi Z, Seiwert T, Grilley-Olson J, Day T, Gillison M, Wade JL, Feldman L, Jha G, Kozloff M, O'Leary M, Worden FP, Cohen EEW. PMID: 36194164; PMCID: PMC9722644.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsCTClinical Trials
    4. Risk factors for breast cancer mortality after ductal carcinoma in situ diagnosis differ from those for invasive recurrence. Surgery. 2023 Feb; 173(2):305-311. O'Keefe TJ, Chau H, Harismendy O, Wallace AM. PMID: 36435650.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Assessing Unique Risk Factors for COVID-19 Complications Among Cancer Patients: A Multi-ethnic Cohort Study. J Immigr Minor Health. 2022 Nov 07. Borno HT, Kim MO, Tolstykh I, Lin A, Hong JC, Yousefi S, Zhang S, McKay RR, Harismendy O, Razavi P, Cinar P, Rugo H, Koshkin VS, Rabow M, Wang C, Bailey A, Small EJ. PMID: 36344859; PMCID: PMC9640901.
      View in: PubMed   Mentions:    Fields:    
    6. ASO Visual Abstract: Co-localization of Gastrointestinal Stromal Tumors (GIST) and Peritoneal Mesothelioma: A Case Series. Ann Surg Oncol. 2022 11; 29(12):7551-7552. Courelli AS, Sharma AK, Madlensky L, Choi YY, Li S, Sarno S, Kelly K, Mehtsun W, Horgan S, Harismendy O, Baumgartner JM, Sicklick JK. PMID: 36064993.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment. Cell Rep. 2022 08 16; 40(7):111201. Papadas A, Deb G, Cicala A, Officer A, Hope C, Pagenkopf A, Flietner E, Morrow ZT, Emmerich P, Wiesner J, Arauz G, Bansal V, Esbona K, Capitini CM, Matkowskyj KA, Deming DA, Politi K, Abrams SI, Harismendy O, Asimakopoulos F. PMID: 35977482; PMCID: PMC9402878.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    8. Co-Localization of Gastrointestinal Stromal Tumors (GIST) and Peritoneal Mesothelioma: A Case Series. Ann Surg Oncol. 2022 Nov; 29(12):7542-7548. Courelli AS, Sharma AK, Madlensky L, Choi YY, Li S, Sarno S, Kelly K, Mehtsun W, Horgan S, Harismendy O, Baumgartner JM, Sicklick JK. PMID: 35849291.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Single-cell characterization of step-wise acquisition of carboplatin resistance in ovarian cancer. NPJ Syst Biol Appl. 2022 06 17; 8(1):20. Wenzel AT, Champa D, Venkatesh H, Sun S, Tsai CY, Mesirov JP, Bui JD, Howell SB, Harismendy O. PMID: 35715421; PMCID: PMC9206019.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. COVID-19 Outcomes Among Patients With Cancer: Observations From the University of California Cancer Consortium COVID-19 Project Outcomes Registry. Oncologist. 2022 05 06; 27(5):398-406. Borno HT, Kim MO, Hong JC, Yousefi S, Lin A, Tolstykh I, Zhang S, McKay RR, Harismendy O, Cinar P, Rugo H, Koshkin VS, Rabow M, Wang C, Bailey A, Small EJ. PMID: 35348771; PMCID: PMC9074994.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Histopathological growth distribution of ductal carcinoma in situ: tumor size is not "one size fits all". Gland Surg. 2022 Feb; 11(2):307-318. O'Keefe TJ, Harismendy O, Wallace AM. PMID: 35284308; PMCID: PMC8899433.
      View in: PubMed   Mentions:
    12. Stem-like breast cancer cells in the activated state resist genetic stress via TGFBI-ZEB1. NPJ Breast Cancer. 2022 Jan 13; 8(1):5. Sun Q, Wang Y, Officer A, Pecknold B, Lee G, Harismendy O, Desgrosellier JS. PMID: 35027548; PMCID: PMC8758745.
      View in: PubMed   Mentions: 3  
    13. The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ. NPJ Breast Cancer. 2022 Jan 13; 8(1):6. Nachmanson D, Officer A, Mori H, Gordon J, Evans MF, Steward J, Yao H, O'Keefe T, Hasteh F, Stein GS, Jepsen K, Weaver DL, Hirst GL, Sprague BL, Esserman LJ, Borowsky AD, Stein JL, Harismendy O. PMID: 35027560; PMCID: PMC8758681.
      View in: PubMed   Mentions: 4  
    14. Large and diffuse ductal carcinoma in situ: potentially lethal subtypes of "preinvasive" disease. Int J Clin Oncol. 2022 Jan; 27(1):121-130. O'Keefe TJ, Harismendy O, Wallace AM. PMID: 34618239.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Inhibition of mTOR signaling and clinical activity of metformin in oral premalignant lesions. JCI Insight. 2021 09 08; 6(17). Gutkind JS, Molinolo AA, Wu X, Wang Z, Nachmanson D, Harismendy O, Alexandrov LB, Wuertz BR, Ondrey FG, Laronde D, Rock LD, Rosin M, Coffey C, Butler VD, Bengtson L, Hsu CH, Bauman JE, Hewitt SM, Cohen EE, Chow HS, Lippman SM, Szabo E. PMID: 34255745; PMCID: PMC8492350.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    16. Genomics Links Inflammation With Neurocognitive Impairment in Children Living With Human Immunodeficiency Virus Type-1. J Infect Dis. 2021 09 01; 224(5):870-880. Rawat P, Brummel SS, Singh KK, Kim J, Frazer KA, Nichols S, Seage GR, Williams PL, Van Dyke RB, Harismendy O, Trout RN, Spector SA. PMID: 33373444; PMCID: PMC8408770.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    17. Establishment of Patient-Derived Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response. Clin Cancer Res. 2022 01 01; 28(1):187-200. Yebra M, Bhargava S, Kumar A, Burgoyne AM, Tang CM, Yoon H, Banerjee S, Aguilera J, Cordes T, Sheth V, Noh S, Ustoy R, Li S, Advani SJ, Corless CL, Heinrich MC, Kurzrock R, Lippman SM, Fanta PT, Harismendy O, Metallo C, Sicklick JK. PMID: 34426440; PMCID: PMC8738129.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. Prevalence of cancer susceptibility variants in patients with multiple Lynch syndrome related cancers. Sci Rep. 2021 07 20; 11(1):14807. Choi YY, Shin SJ, Lee JE, Madlensky L, Lee ST, Park JS, Jo JH, Kim H, Nachmanson D, Xu X, Noh SH, Cheong JH, Harismendy O. PMID: 34285288; PMCID: PMC8292343.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Synchronous, Yet Genomically Distinct, GIST Offer New Insights Into Precise Targeting of Tumor Driver Mutations. JCO Precis Oncol. 2021; 5. Makris EA, Sharma AK, Bergstrom EN, Xu X, de la Torre J, Banerjee S, Nguyen V, Hosseini M, Burgoyne A, Harismendy O, Alexandrov LB, Sicklick JK. PMID: 34250403; PMCID: PMC8232556.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Cancer-associated fibroblast secretion of PDGFC promotes gastrointestinal stromal tumor growth and metastasis. Oncogene. 2021 03; 40(11):1957-1973. Yoon H, Tang CM, Banerjee S, Yebra M, Noh S, Burgoyne AM, Torre J, Siena M, Liu M, Klug LR, Choi YY, Hosseini M, Delgado AL, Wang Z, French RP, Lowy A, DeMatteo RP, Heinrich MC, Molinolo AA, Gutkind JS, Harismendy O, Sicklick JK. PMID: 33603171; PMCID: PMC7979540.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    21. Immune-related IncRNA LINC00944 responds to variations in ADAR1 levels and it is associated with breast cancer prognosis. Life Sci. 2021 Mar 01; 268:118956. de Santiago PR, Blanco A, Morales F, Marcelain K, Harismendy O, Sj?berg Herrera M, Armis?n R. PMID: 33383047.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    22. Mutational profiling of micro-dissected pre-malignant lesions from archived specimens. BMC Med Genomics. 2020 11 18; 13(1):173. Nachmanson D, Steward J, Yao H, Officer A, Jeong E, O'Keefe TJ, Hasteh F, Jepsen K, Hirst GL, Esserman LJ, Borowsky AD, Harismendy O. PMID: 33208147; PMCID: PMC7672910.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    23. Deciphering cell-cell interactions and communication from gene expression. Nat Rev Genet. 2021 02; 22(2):71-88. Armingol E, Officer A, Harismendy O, Lewis NE. PMID: 33168968; PMCID: PMC7649713.
      View in: PubMed   Mentions: 171     Fields:    Translation:HumansAnimalsCells
    24. HER2-Overexpressing Ductal Carcinoma In Situ Associated with Increased Risk of Ipsilateral Invasive Recurrence, Receptor Discordance with Recurrence. Cancer Prev Res (Phila). 2020 09; 13(9):761-772. O'Keefe TJ, Blair SL, Hosseini A, Harismendy O, Wallace AM. PMID: 32493703; PMCID: PMC7483601.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. PLoS Genet. 2020 01; 16(1):e1008558. Delaney JR, Patel CB, Bapat J, Jones CM, Ramos-Zapatero M, Ortell KK, Tanios R, Haghighiabyaneh M, Axelrod J, DeStefano JW, Tancioni I, Schlaepfer DD, Harismendy O, La Spada AR, Stupack DG. PMID: 31923184; PMCID: PMC6953790.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    26. HNRNPK maintains epidermal progenitor function through transcription of proliferation genes and degrading differentiation promoting mRNAs. Nat Commun. 2019 09 13; 10(1):4198. Li J, Chen Y, Xu X, Jones J, Tiwari M, Ling J, Wang Y, Harismendy O, Sen GL. PMID: 31519929; PMCID: PMC6744489.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    27. Illuminating the Onco-GPCRome: Novel G protein-coupled receptor-driven oncocrine networks and targets for cancer immunotherapy. J Biol Chem. 2019 07 19; 294(29):11062-11086. Wu V, Yeerna H, Nohata N, Chiou J, Harismendy O, Raimondi F, Inoue A, Russell RB, Tamayo P, Gutkind JS. PMID: 31171722; PMCID: PMC6643028.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    28. Evaluating and sharing global genetic ancestry in biomedical datasets. J Am Med Inform Assoc. 2019 05 01; 26(5):457-461. Harismendy O, Kim J, Xu X, Ohno-Machado L. PMID: 30869786; PMCID: PMC6433181.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    29. Activation of hedgehog signaling associates with early disease progression in chronic lymphocytic leukemia. Blood. 2019 06 20; 133(25):2651-2663. Ghia EM, Rassenti LZ, Neuberg DS, Blanco A, Yousif F, Smith EN, McPherson JD, Hudson TJ, HALT Pan-Leukemia Gene Panel Consortium, Harismendy O, Frazer KA, Kipps TJ. PMID: 30923040; PMCID: PMC6587306.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    30. Inhibition of mTOR Signaling and Clinical Activity of Rapamycin in Head and Neck Cancer in a Window of Opportunity Trial. Clin Cancer Res. 2019 02 15; 25(4):1156-1164. Day TA, Shirai K, O'Brien PE, Matheus MG, Godwin K, Sood AJ, Kompelli A, Vick JA, Martin D, Vitale-Cross L, Callejas-Varela JL, Wang Z, Wu X, Harismendy O, Molinolo AA, Lippman SM, Van Waes C, Szabo E, Gutkind JS. PMID: 30420444; PMCID: PMC6377824.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    31. ADAR1-mediated RNA-editing of 3'UTRs in breast cancer. Biol Res. 2018 Oct 05; 51(1):36. Sagredo EA, Blanco A, Sagredo AI, P?rez P, Sep?lveda-Hermosilla G, Morales F, M?ller B, Verdugo R, Marcelain K, Harismendy O, Armis?n R. PMID: 30290838; PMCID: PMC6172785.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    32. Integrative genomic analysis of mouse and human hepatocellular carcinoma. Proc Natl Acad Sci U S A. 2018 10 16; 115(42):E9879-E9888. Dow M, Pyke RM, Tsui BY, Alexandrov LB, Nakagawa H, Taniguchi K, Seki E, Harismendy O, Shalapour S, Karin M, Carter H, Font-Burgada J. PMID: 30287485; PMCID: PMC6196518.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    33. Prognostic Importance of Age, Tumor Location, and Tumor Grade in Grade II Astrocytomas: An Integrated Analysis of the Cancer Genome Atlas and the Surveillance, Epidemiology, and End Results Database. World Neurosurg. 2019 Jan; 121:e411-e418. Alattar AA, Carroll KT, Bryant AK, Hirshman B, Joshi R, Carter BS, Harismendy O, Chen CC. PMID: 30266697.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    34. Exome-wide analysis of bi-allelic alterations identifies a Lynch phenotype in The Cancer Genome Atlas. Genome Med. 2018 09 14; 10(1):69. Buckley AR, Ideker T, Carter H, Harismendy O, Schork NJ. PMID: 30217226; PMCID: PMC6138910.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    35. Genomic Landscape of Appendiceal Neoplasms. JCO Precis Oncol. 2018; 2. Ang CS, Shen JP, Hardy-Abeloos CJ, Huang JK, Ross JS, Miller VA, Jacobs MT, Chen IL, Xu D, Ali SM, Baumgartner J, Lowy A, Fanta P, Ideker T, Millis SZ, Harismendy O. PMID: 32913983; PMCID: PMC7446344.
      View in: PubMed   Mentions: 5     Fields:    
    36. Nuclear respiratory factor 1 promotes spheroid survival and mesenchymal transition in mammary epithelial cells. Oncogene. 2018 11; 37(47):6152-6165. Zhou Y, Xu Z, Quan D, Zhang F, Zhang H, Xiao T, Hou S, Qiao H, Harismendy O, Wang JYJ, Suo G. PMID: 29995872; PMCID: PMC6329670.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    37. Interaction Between the Contributions of Tumor Location, Tumor Grade, and Patient Age to the Survival Benefit Associated with Gross Total Resection. World Neurosurg. 2018 Mar; 111:e790-e798. Carroll KT, Bryant AK, Hirshman B, Alattar AA, Joshi R, Gabel B, Carter BS, Harismendy O, Vaida F, Chen CC. PMID: 29309983.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    38. PinAPL-Py: A comprehensive web-application for the analysis of CRISPR/Cas9 screens. Sci Rep. 2017 Nov 20; 7(1):15854. Spahn PN, Bath T, Weiss RJ, Kim J, Esko JD, Lewis NE, Harismendy O. PMID: 29158538; PMCID: PMC5696473.
      View in: PubMed   Mentions: 33     Fields:    
    39. Duodenal-Jejunal Flexure GI Stromal Tumor Frequently Heralds Somatic NF1 and Notch Pathway Mutations. JCO Precis Oncol. 2017; 2017. Burgoyne AM, De Siena M, Alkhuziem M, Tang CM, Medina B, Fanta PT, Belinsky MG, von Mehren M, Thorson JA, Madlensky L, Bowler T, D'Angelo F, Stupack DG, Harismendy O, DeMatteo RP, Sicklick JK. PMID: 29938249; PMCID: PMC6013064.
      View in: PubMed   Mentions: 9     Fields:    
    40. Deep mining heterogeneous networks of biomedical linked data to predict novel drug-target associations. Bioinformatics. 2017 Aug 01; 33(15):2337-2344. Zong N, Kim H, Ngo V, Harismendy O. PMID: 28430977; PMCID: PMC5860112.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    41. Pan-cancer analysis reveals technical artifacts in TCGA germline variant calls. BMC Genomics. 2017 06 12; 18(1):458. Buckley AR, Standish KA, Bhutani K, Ideker T, Lasken RS, Carter H, Harismendy O, Schork NJ. PMID: 28606096; PMCID: PMC5467262.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    42. iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types. Stem Cell Reports. 2017 04 11; 8(4):1086-1100. Panopoulos AD, D'Antonio M, Benaglio P, Williams R, Hashem SI, Schuldt BM, DeBoever C, Arias AD, Garcia M, Nelson BC, Harismendy O, Jakubosky DA, Donovan MKR, Greenwald WW, Farnam K, Cook M, Borja V, Miller CA, Grinstein JD, Drees F, Okubo J, Diffenderfer KE, Hishida Y, Modesto V, Dargitz CT, Feiring R, Zhao C, Aguirre A, McGarry TJ, Matsui H, Li H, Reyna J, Rao F, O'Connor DT, Yeo GW, Evans SM, Chi NC, Jepsen K, Nariai N, M?ller FJ, Goldstein LSB, Izpisua Belmonte JC, Adler E, Loring JF, Berggren WT, D'Antonio-Chronowska A, Smith EN, Frazer KA. PMID: 28410642; PMCID: PMC5390244.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    43. Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. Nat Commun. 2017 02 15; 8:14423. Delaney JR, Patel CB, Willis KM, Haghighiabyaneh M, Axelrod J, Tancioni I, Lu D, Bapat J, Young S, Cadassou O, Bartakova A, Sheth P, Haft C, Hui S, Saenz C, Schlaepfer DD, Harismendy O, Stupack DG. PMID: 28198375; PMCID: PMC5316854.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    44. Whole genome sequencing of an African American family highlights toll like receptor 6 variants in Kawasaki disease susceptibility. PLoS One. 2017; 12(2):e0170977. Kim J, Shimizu C, Kingsmore SF, Veeraraghavan N, Levy E, Ribeiro Dos Santos AM, Yang H, Flatley J, Hoang LT, Hibberd ML, Tremoulet AH, Harismendy O, Ohno-Machado L, Burns JC. PMID: 28151979; PMCID: PMC5289527.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    45. FGFR1 and NTRK3 actionable alterations in "Wild-Type" gastrointestinal stromal tumors. J Transl Med. 2016 12 14; 14(1):339. Shi E, Chmielecki J, Tang CM, Wang K, Heinrich MC, Kang G, Corless CL, Hong D, Fero KE, Murphy JD, Fanta PT, Ali SM, De Siena M, Burgoyne AM, Movva S, Madlensky L, Heestand GM, Trent JC, Kurzrock R, Morosini D, Ross JS, Harismendy O, Sicklick JK. PMID: 27974047; PMCID: PMC5157084.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    46. Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression. Oncotarget. 2016 Nov 29; 7(48):78226-78241. Tang CM, Lee TE, Syed SA, Burgoyne AM, Leonard SY, Gao F, Chan JC, Shi E, Chmielecki J, Morosini D, Wang K, Ross JS, Kendrick ML, Bardsley MR, Siena M, Mao J, Harismendy O, Ordog T, Sicklick JK. PMID: 27793025; PMCID: PMC5346634.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    47. Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance. Cell Rep. 2016 08 30; 16(9):2348-58. Saddawi-Konefka R, Seelige R, Gross ET, Levy E, Searles SC, Washington A, Santosa EK, Liu B, O'Sullivan TE, Harismendy O, Bui JD. PMID: 27545889; PMCID: PMC5007173.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    48. Immune DNA signature of T-cell infiltration in breast tumor exomes. Sci Rep. 2016 07 25; 6:30064. Levy E, Marty R, G?rate Calder?n V, Woo B, Dow M, Armisen R, Carter H, Harismendy O. PMID: 27452728; PMCID: PMC4958917.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    49. Use of Liquid Biopsies in Clinical Oncology: Pilot Experience in 168 Patients. Clin Cancer Res. 2016 Nov 15; 22(22):5497-5505. Schwaederle M, Husain H, Fanta PT, Piccioni DE, Kesari S, Schwab RB, Patel SP, Harismendy O, Ikeda M, Parker BA, Kurzrock R. PMID: 27185373.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCTClinical Trials
    50. Cronkhite Canada Syndrome: Significant Response to Infliximab and a Possible Clue to Pathogenesis. Am J Gastroenterol. 2016 05; 111(5):746-8. Boland BS, Bagi P, Valasek MA, Chang JT, Bustamante R, Madlensky L, Sandborn WJ, Harismendy O, Gupta S. PMID: 27151126; PMCID: PMC5824983.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    51. Mutational Profiling Can Establish Clonal or Independent Origin in Synchronous Bilateral Breast and Other Tumors. PLoS One. 2015; 10(11):e0142487. Bao L, Messer K, Schwab R, Harismendy O, Pu M, Crain B, Yost S, Frazer KA, Rana B, Hasteh F, Wallace A, Parker BA. PMID: 26554380; PMCID: PMC4640562.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    52. Both GLUT-1 and GLUT-14 are Independent Prognostic Factors in Gastric Adenocarcinoma. Ann Surg Oncol. 2015 Dec; 22 Suppl 3:S822-31. Berlth F, M?nig S, Pinther B, Grimminger P, Maus M, Schl?sser H, Plum P, Warnecke-Eberz U, Harismendy O, Drebber U, Bollschweiler E, H?lscher A, Alakus H. PMID: 26183839.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    53. Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression. Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30):E4055-64. Kozono D, Li J, Nitta M, Sampetrean O, Gonda D, Kushwaha DS, Merzon D, Ramakrishnan V, Zhu S, Zhu K, Matsui H, Harismendy O, Hua W, Mao Y, Kwon CH, Saya H, Nakano I, Pizzo DP, VandenBerg SR, Chen CC. PMID: 26159421; PMCID: PMC4522819.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    54. BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma. J Transl Med. 2015 Apr 16; 13:122. Alakus H, Yost SE, Woo B, French R, Lin GY, Jepsen K, Frazer KA, Lowy AM, Harismendy O. PMID: 25889843; PMCID: PMC4422481.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    55. Genetic and epigenetic profiling of CLL disease progression reveals limited somatic evolution and suggests a relationship to memory-cell development. Blood Cancer J. 2015 Apr 10; 5:e303. Smith EN, Ghia EM, DeBoever CM, Rassenti LZ, Jepsen K, Yoon KA, Matsui H, Rozenzhak S, Alakus H, Shepard PJ, Dai Y, Khosroheidari M, Bina M, Gunderson KL, Messer K, Muthuswamy L, Hudson TJ, Harismendy O, Barrett CL, Jamieson CH, Carson DA, Kipps TJ, Frazer KA. PMID: 25860294; PMCID: PMC4450323.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    56. Immunodeficiency and autoimmune enterocolopathy linked to NFAT5 haploinsufficiency. J Immunol. 2015 Mar 15; 194(6):2551-60. Boland BS, Widjaja CE, Banno A, Zhang B, Kim SH, Stoven S, Peterson MR, Jones MC, Su HI, Crowe SE, Bui JD, Ho SB, Okugawa Y, Goel A, Marietta EV, Khosroheidari M, Jepsen K, Aramburu J, L?pez-Rodr?guez C, Sandborn WJ, Murray JA, Harismendy O, Chang JT. PMID: 25667416; PMCID: PMC4355235.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    57. Correction: Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin. Genome Med. 2014; 6(7):53. Alakus H, Babicky ML, Ghosh P, Yost S, Jepsen K, Dai Y, Arias A, Samuels ML, Mose ES, Schwab RB, Peterson MR, Lowy AM, Frazer KA, Harismendy O. PMID: 25228923; PMCID: PMC4165363.
      View in: PubMed   Mentions: 1     Fields:    
    58. Network-based analysis identifies epigenetic biomarkers of esophageal squamous cell carcinoma progression. Bioinformatics. 2014 Nov 01; 30(21):3054-61. Cheng CP, Kuo IY, Alakus H, Frazer KA, Harismendy O, Wang YC, Tseng VS. PMID: 25015989; PMCID: PMC4609006.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    59. Homozygous GNAS 393C-allele carriers with locally advanced esophageal cancer fail to benefit from platinum-based preoperative chemoradiotherapy. Ann Surg Oncol. 2014 Dec; 21(13):4375-82. Alakus H, Bollschweiler E, H?lscher AH, Warnecke-Eberz U, Frazer KA, Harismendy O, Lowy AM, M?nig SP, Eberz PM, Maus M, Drebber U, Siffert W, Metzger R. PMID: 24986238.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    60. Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin. Genome Med. 2014; 6(5):43. Alakus H, Babicky ML, Ghosh P, Yost S, Jepsen K, Dai Y, Arias A, Samuels ML, Mose ES, Schwab RB, Peterson MR, Lowy AM, Frazer KA, Harismendy O. PMID: 24944587; PMCID: PMC4062050.
      View in: PubMed   Mentions: 42     Fields:    
    61. Evaluation of ultra-deep targeted sequencing for personalized breast cancer care. Breast Cancer Res. 2013 Dec 10; 15(6):R115. Harismendy O, Schwab RB, Alakus H, Yost SE, Matsui H, Hasteh F, Wallace AM, Park HL, Madlensky L, Parker B, Carpenter PM, Jepsen K, Anton-Culver H, Frazer KA. PMID: 24326041; PMCID: PMC3978701.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    62. Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling. Cell. 2013 Oct 10; 155(2):384-96. He G, Dhar D, Nakagawa H, Font-Burgada J, Ogata H, Jiang Y, Shalapour S, Seki E, Yost SE, Jepsen K, Frazer KA, Harismendy O, Hatziapostolou M, Iliopoulos D, Suetsugu A, Hoffman RM, Tateishi R, Koike K, Karin M. PMID: 24120137; PMCID: PMC4015514.
      View in: PubMed   Mentions: 216     Fields:    Translation:AnimalsCells
    63. Whole transcriptome sequencing enables discovery and analysis of viruses in archived primary central nervous system lymphomas. PLoS One. 2013; 8(9):e73956. DeBoever C, Reid EG, Smith EN, Wang X, Dumaop W, Harismendy O, Carson D, Richman D, Masliah E, Frazer KA. PMID: 24023918; PMCID: PMC3762708.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    64. Mutascope: sensitive detection of somatic mutations from deep amplicon sequencing. Bioinformatics. 2013 Aug 01; 29(15):1908-9. Yost SE, Alakus H, Matsui H, Schwab RB, Jepsen K, Frazer KA, Harismendy O. PMID: 23712659; PMCID: PMC3712217.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    65. Transcriptome sequencing of tumor subpopulations reveals a spectrum of therapeutic options for squamous cell lung cancer. PLoS One. 2013; 8(3):e58714. Barrett CL, Schwab RB, Jung H, Crain B, Goff DJ, Jamieson CH, Thistlethwaite PA, Harismendy O, Carson DA, Frazer KA. PMID: 23527012; PMCID: PMC3604164.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    66. High-resolution mutational profiling suggests the genetic validity of glioblastoma patient-derived pre-clinical models. PLoS One. 2013; 8(2):e56185. Yost SE, Pastorino S, Rozenzhak S, Smith EN, Chao YS, Jiang P, Kesari S, Frazer KA, Harismendy O. PMID: 23441165; PMCID: PMC3575368.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    67. Identification of high-confidence somatic mutations in whole genome sequence of formalin-fixed breast cancer specimens. Nucleic Acids Res. 2012 Aug; 40(14):e107. Yost SE, Smith EN, Schwab RB, Bao L, Jung H, Wang X, Voest E, Pierce JP, Messer K, Parker BA, Harismendy O, Frazer KA. PMID: 22492626; PMCID: PMC3413110.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    68. Genomics in 2011: challenges and opportunities. Genome Biol. 2011 Dec 28; 12(12):137. Adams DJ, Berger B, Harismendy O, Huttenhower C, Liu XS, Myers CL, Oshlack A, Rinn JL, Walhout AJ. PMID: 22204305; PMCID: PMC3334607.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    69. Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing. Genome Biol. 2011 Dec 20; 12(12):R124. Harismendy O, Schwab RB, Bao L, Olson J, Rozenzhak S, Kotsopoulos SK, Pond S, Crain B, Chee MS, Messer K, Link DR, Frazer KA. PMID: 22185227; PMCID: PMC3334619.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    70. Sensitive gene fusion detection using ambiguously mapping RNA-Seq read pairs. Bioinformatics. 2011 Apr 15; 27(8):1068-75. Kinsella M, Harismendy O, Nakano M, Frazer KA, Bafna V. PMID: 21330288; PMCID: PMC3072550.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    71. 9p21 DNA variants associated with coronary artery disease impair interferon-? signalling response. Nature. 2011 Feb 10; 470(7333):264-8. Harismendy O, Notani D, Song X, Rahim NG, Tanasa B, Heintzman N, Ren B, Fu XD, Topol EJ, Rosenfeld MG, Frazer KA. PMID: 21307941; PMCID: PMC3079517.
      View in: PubMed   Mentions: 293     Fields:    Translation:HumansCells
    72. Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level. Genome Biol. 2010; 11(11):R118. Harismendy O, Bansal V, Bhatia G, Nakano M, Scott M, Wang X, Dib C, Turlotte E, Sipe JC, Murray SS, Deleuze JF, Bafna V, Topol EJ, Frazer KA. PMID: 21118518; PMCID: PMC3156957.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    73. A covering method for detecting genetic associations between rare variants and common phenotypes. PLoS Comput Biol. 2010 Oct 14; 6(10):e1000954. Bhatia G, Bansal V, Harismendy O, Schork NJ, Topol EJ, Frazer K, Bafna V. PMID: 20976246; PMCID: PMC2954823.
      View in: PubMed   Mentions: 55     Fields:    
    74. Accurate detection and genotyping of SNPs utilizing population sequencing data. Genome Res. 2010 Apr; 20(4):537-45. Bansal V, Harismendy O, Tewhey R, Murray SS, Schork NJ, Topol EJ, Frazer KA. PMID: 20150320; PMCID: PMC2847757.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    75. Biomarkers of endocannabinoid system activation in severe obesity. PLoS One. 2010 Jan 20; 5(1):e8792. Sipe JC, Scott TM, Murray S, Harismendy O, Simon GM, Cravatt BF, Waalen J. PMID: 20098695; PMCID: PMC2808340.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    76. Microdroplet-based PCR enrichment for large-scale targeted sequencing. Nat Biotechnol. 2009 Nov; 27(11):1025-31. Tewhey R, Warner JB, Nakano M, Libby B, Medkova M, David PH, Kotsopoulos SK, Samuels ML, Hutchison JB, Larson JW, Topol EJ, Weiner MP, Harismendy O, Olson J, Link DR, Frazer KA. PMID: 19881494; PMCID: PMC2779736.
      View in: PubMed   Mentions: 159     Fields:    Translation:HumansCells
    77. Enrichment of sequencing targets from the human genome by solution hybridization. Genome Biol. 2009; 10(10):R116. Tewhey R, Nakano M, Wang X, Pabón-Peña C, Novak B, Giuffre A, Lin E, Happe S, Roberts DN, LeProust EM, Topol EJ, Harismendy O, Frazer KA. PMID: 19835619; PMCID: PMC2784331.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    78. Elucidating the role of 8q24 in colorectal cancer. Nat Genet. 2009 Aug; 41(8):868-9. Harismendy O, Frazer KA. PMID: 19639026.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    79. Evaluation of next generation sequencing platforms for population targeted sequencing studies. Genome Biol. 2009; 10(3):R32. Harismendy O, Ng PC, Strausberg RL, Wang X, Stockwell TB, Beeson KY, Schork NJ, Murray SS, Topol EJ, Levy S, Frazer KA. PMID: 19327155; PMCID: PMC2691003.
      View in: PubMed   Mentions: 269     Fields:    Translation:HumansCells
    80. Method for improving sequence coverage uniformity of targeted genomic intervals amplified by LR-PCR using Illumina GA sequencing-by-synthesis technology. Biotechniques. 2009 Mar; 46(3):229-31. Harismendy O, Frazer K. PMID: 19317667.
      View in: PubMed   Mentions: 31     Fields:    
    81. Genetic determinants of phenotypic diversity in humans. Genome Biol. 2008 Apr 24; 9(4):215. Rahim NG, Harismendy O, Topol EJ, Frazer KA. PMID: 18439327; PMCID: PMC2643926.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    82. Maf1 is involved in coupling carbon metabolism to RNA polymerase III transcription. Mol Cell Biol. 2007 Nov; 27(21):7693-702. Ciesla M, Towpik J, Graczyk D, Oficjalska-Pham D, Harismendy O, Suleau A, Balicki K, Conesa C, Lefebvre O, Boguta M. PMID: 17785443; PMCID: PMC2169064.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    83. Nucleosome depletion activates poised RNA polymerase III at unconventional transcription sites in Saccharomyces cerevisiae. J Biol Chem. 2006 Sep 29; 281(39):29155-64. Guffanti E, Percudani R, Harismendy O, Soutourina J, Werner M, Iacovella MG, Negri R, Dieci G. PMID: 16816405.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    84. A minimal promoter for TFIIIC-dependent in vitro transcription of snoRNA and tRNA genes by RNA polymerase III. J Biol Chem. 2006 Aug 18; 281(33):23945-57. Guffanti E, Ferrari R, Preti M, Forloni M, Harismendy O, Lefebvre O, Dieci G. PMID: 16787917.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    85. General repression of RNA polymerase III transcription is triggered by protein phosphatase type 2A-mediated dephosphorylation of Maf1. Mol Cell. 2006 Jun 09; 22(5):623-32. Oficjalska-Pham D, Harismendy O, Smagowicz WJ, Gonzalez de Peredo A, Boguta M, Sentenac A, Lefebvre O. PMID: 16762835.
      View in: PubMed   Mentions: 85     Fields:    Translation:Cells
    86. Genome-wide location of yeast RNA polymerase III transcription machinery. EMBO J. 2003 Sep 15; 22(18):4738-47. Harismendy O, Gendrel CG, Soularue P, Gidrol X, Sentenac A, Werner M, Lefebvre O. PMID: 12970186; PMCID: PMC212732.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    With one click, see people who:

    Mentor Faculty

    Run Clinical Trials

    See more options in the Advanced Search tab

    Olivier's Networks
    Concepts (447)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (118)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSD Profiles is managed by the UC San Diego Altman Clinical and Translational Research Institute (ACTRI).
    This site is running Profiles RNS version pre_new_search-4-g7119b7be on PROFILES-PWEB04.

    Copyright © The Regents of the University of California