Nils Svensson

Title(s)Assistant Adjunct Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0001-8077-9824 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Gothenburg, Gothenburg, SwedenMSc2009Pharmacy
    University of Gothenburg, Gothenburg, SwedenPhD2014Immunology and Rheumatology
    Collapse Awards and Honors
    2019Arthritis National Research Foundation Scholar

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Pathogenic role of ILC2 in rheumatoid arthritis
    NIH R21AR076578Sep 24, 2020 - Aug 31, 2022
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Activated low-density granulocytes in peripheral and intervillous blood and neutrophil inflammation in placentas from SLE pregnancies. Lupus Sci Med. 2021 03; 8(1). Stockfelt M, Larsson G, Engstr?m H, Puttonen H, Zetterberg H, Blennow K, Sj?wall C, Strevens H, J?nsen A, Bengtsson AA, Majczuk Sennstr?m M, Zickert A, Svenungsson E, Gunnarsson I, Trysberg E, Jacobsson B, Hultg?rd Ekwall AK, Christenson K, Bylund J, Svensson MND, Lundell AC. PMID: 33685997; PMCID: PMC7942245.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    2. PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis. JCI Insight. 2020 10 15; 5(20). Hsieh WC, Svensson MN, Zoccheddu M, Tremblay ML, Sakaguchi S, Stanford SM, Bottini N. PMID: 33055428; PMCID: PMC7605542.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    3. Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. Sci Adv. 2020 06; 6(26):eaba4353. Svensson MND, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody KM, Slowikowski K, Mizoguchi F, Humby F, Hands R, Santelli E, Sacchetti C, Wakabayashi K, Wu DJ, Barback C, Ai R, Wang W, Sims GP, Mydel P, Kasama T, Boyle DL, Galimi F, Vera D, Tremblay ML, Raychaudhuri S, Brenner MB, Firestein GS, Pitzalis C, Ekwall AH, Stanford SM, Bottini N. PMID: 32637608; PMCID: PMC7319753.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    4. PTPN22 phosphorylation acts as a molecular rheostat for the inhibition of TCR signaling. Sci Signal. 2020 03 17; 13(623). Yang S, Svensson MND, Harder NHO, Hsieh WC, Santelli E, Kiosses WB, Moresco JJ, Yates JR, King CC, Liu L, Stanford SM, Bottini N. PMID: 32184287; PMCID: PMC7263369.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    5. RPTPa phosphatase activity is allosterically regulated by the membrane-distal catalytic domain. J Biol Chem. 2020 04 10; 295(15):4923-4936. Wen Y, Yang S, Wakabayashi K, Svensson MND, Stanford SM, Santelli E, Bottini N. PMID: 32139509; PMCID: PMC7152759.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    6. Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity. J Clin Invest. 2019 03 01; 129(3):1193-1210. Svensson MN, Doody KM, Schmiedel BJ, Bhattacharyya S, Panwar B, Wiede F, Yang S, Santelli E, Wu DJ, Sacchetti C, Gujar R, Seumois G, Kiosses WB, Aubry I, Kim G, Mydel P, Sakaguchi S, Kronenberg M, Tiganis T, Tremblay ML, Ay F, Vijayanand P, Bottini N. PMID: 30620725; PMCID: PMC6391091.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    7. Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70. Nat Commun. 2018 07 06; 9(1):2627. Zhao M, Svensson MND, Venken K, Chawla A, Liang S, Engel I, Mydel P, Day J, Elewaut D, Bottini N, Kronenberg M. PMID: 29980684; PMCID: PMC6035278.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    8. IGF-1R signalling contributes to IL-6 production and T cell dependent inflammation in rheumatoid arthritis. Biochim Biophys Acta Mol Basis Dis. 2017 09; 1863(9):2158-2170. Erlandsson MC, T?yr? Silfversw?rd S, Nadali M, Turkkila M, Svensson MND, Jonsson IM, Andersson KME, Bokarewa MI. PMID: 28583713.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    9. RAGE Deficiency Impairs Bacterial Clearance in Murine Staphylococcal Sepsis, but Has No Significant Impact on Staphylococcal Septic Arthritis. PLoS One. 2016; 11(12):e0167287. Mohammad M, Na M, Welin A, Svensson MN, Ali A, Jin T, Pullerits R. PMID: 27907047; PMCID: PMC5131947.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    10. Receptor Protein Tyrosine Phosphatase a-Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice. Arthritis Rheumatol. 2016 Feb; 68(2):359-69. Stanford SM, Svensson MN, Sacchetti C, Pilo CA, Wu DJ, Kiosses WB, Hellvard A, Bergum B, Muench GR, Elly C, Liu YC, den Hertog J, Elson A, Sap J, Mydel P, Boyle DL, Corr M, Firestein GS, Bottini N. PMID: 26414708; PMCID: PMC4770259.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    11. Murine germinal center B cells require functional Fms-like tyrosine kinase 3 signaling for IgG1 class-switch recombination. Proc Natl Acad Sci U S A. 2015 Dec 01; 112(48):E6644-53. Svensson MN, Andersson KM, Was?n C, Erlandsson MC, Nurkkala-Karlsson M, Jonsson IM, Brisslert M, Bemark M, Bokarewa MI. PMID: 26627255; PMCID: PMC4672832.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    12. Impaired signaling through the Fms-like tyrosine kinase 3 receptor increases osteoclast formation and bone damage in arthritis. J Leukoc Biol. 2016 Mar; 99(3):413-23. Svensson MN, Erlandsson MC, Jonsson IM, Andersson KM, Bokarewa MI. PMID: 26392589.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    13. Survivin co-ordinates formation of follicular T-cells acting in synergy with Bcl-6. Oncotarget. 2015 Aug 21; 6(24):20043-57. Andersson KM, Brisslert M, Cavallini NF, Svensson MN, Welin A, Erlandsson MC, Ciesielski MJ, Katona G, Bokarewa MI. PMID: 26343374; PMCID: PMC4652986.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    14. Trabecular bone loss in collagen antibody-induced arthritis. Arthritis Res Ther. 2015 Jul 25; 17:189. Grahnemo L, Andersson A, Nurkkala-Karlsson M, Stubelius A, Lagerquist MK, Svensson MN, Ohlsson C, Carlsten H, Islander U. PMID: 26209517; PMCID: PMC4514982.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    15. IL-1 Receptor Antagonist Treatment Aggravates Staphylococcal Septic Arthritis and Sepsis in Mice. PLoS One. 2015; 10(7):e0131645. Ali A, Na M, Svensson MN, Magnusson M, Welin A, Schwarze JC, Mohammad M, Josefsson E, Pullerits R, Jin T. PMID: 26135738; PMCID: PMC4489902.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    16. Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy. Sci Transl Med. 2015 May 20; 7(288):288ra76. Doody KM, Stanford SM, Sacchetti C, Svensson MN, Coles CH, Mitakidis N, Kiosses WB, Bartok B, Fos C, Cory E, Sah RL, Liu-Bryan R, Boyle DL, Arnett HA, Mustelin T, Corr M, Esko JD, Tremblay ML, Firestein GS, Aricescu AR, Bottini N. PMID: 25995222; PMCID: PMC4458332.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    17. CTLA4 Immunoglobulin but Not Anti-Tumor Necrosis Factor Therapy Promotes Staphylococcal Septic Arthritis in Mice. J Infect Dis. 2015 Oct 15; 212(8):1308-16. Ali A, Welin A, Schwarze JC, Svensson MN, Na M, Jarneborn A, Magnusson M, Mohammad M, Kwiecinski J, Josefsson E, Bylund J, Pullerits R, Jin T. PMID: 25838268.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    18. Down-regulation of survivin alleviates experimental arthritis. J Leukoc Biol. 2015 Jan; 97(1):135-45. Andersson KM, Svensson MN, Erlandsson MC, Jonsson IM, Bokarewa MI. PMID: 25381389.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    19. S100A4 regulates the Src-tyrosine kinase dependent differentiation of Th17 cells in rheumatoid arthritis. Biochim Biophys Acta. 2014 Nov; 1842(11):2049-59. Brisslert M, Bian L, Svensson MN, Santos RF, Jonsson IM, Barsukov I, Erlandsson M, Andersson K, Carmo AM, Bokarewa MI. PMID: 25035294.
      View in: PubMed   Mentions: 4     Fields:    
    20. Expression of metastasin S100A4 is essential for bone resorption and regulates osteoclast function. Biochim Biophys Acta. 2013 Dec; 1833(12):2653-2663. Erlandsson MC, Svensson MD, Jonsson IM, Bian L, Ambartsumian N, Andersson S, Peng Z, V??r?niemi J, Ohlsson C, Andersson KME, Bokarewa MI. PMID: 23830916.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    21. Fms-like tyrosine kinase 3 ligand controls formation of regulatory T cells in autoimmune arthritis. PLoS One. 2013; 8(1):e54884. Svensson MN, Andersson SE, Erlandsson MC, Jonsson IM, Ekwall AK, Andersson KM, Nilsson A, Bian L, Brisslert M, Bokarewa MI. PMID: 23349985; PMCID: PMC3549988.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    22. Activation of Fms-like tyrosine kinase 3 signaling enhances survivin expression in a mouse model of rheumatoid arthritis. PLoS One. 2012; 7(10):e47668. Andersson SE, Svensson MN, Erlandsson MC, Dehlin M, Andersson KM, Bokarewa MI. PMID: 23082191; PMCID: PMC3474718.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    23. Resistin and insulin/insulin-like growth factor signaling in rheumatoid arthritis. Arthritis Rheum. 2011 Oct; 63(10):2894-904. Bostr?m EA, Svensson M, Andersson S, Jonsson IM, Ekwall AK, Eisler T, Dahlberg LE, Smith U, Bokarewa MI. PMID: 21739426.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells