Nelly El-sakkary

Title(s)Postdoctoral Scholar, School of Pharmacy and Pharmaceutical Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation. Eur J Med Chem. 2021 Sep 10; 226:113823. Padalino G, El-Sakkary N, Liu LJ, Liu C, Harte DSG, Barnes RE, Sayers E, Forde-Thomas J, Whiteland H, Bassetto M, Ferla S, Johnson G, Jones AT, Caffrey CR, Chalmers I, Brancale A, Hoffmann KF. PMID: 34536671.
      View in: PubMed   Mentions:    Fields:    
    2. Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis. J Med Chem. 2021 07 08; 64(13):9404-9430. Klug DM, Mavrogiannaki EM, Forbes KC, Silva L, Diaz-Gonzalez R, Pérez-Moreno G, Ceballos-Pérez G, Garcia-Hernández R, Bosch-Navarrete C, Cordón-Obras C, Gómez-Liñán C, Saura A, Momper JD, Martinez-Martinez MS, Manzano P, Syed A, El-Sakkary N, Caffrey CR, Gamarro F, Ruiz-Perez LM, Gonzalez Pacanowska D, Ferrins L, Navarro M, Pollastri MP. PMID: 34156862; PMCID: PMC8412142.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. A Machine Learning Strategy for Drug Discovery Identifies Anti-Schistosomal Small Molecules. ACS Infect Dis. 2021 02 12; 7(2):406-420. Zorn KM, Sun S, McConnon CL, Ma K, Chen EK, Foil DH, Lane TR, Liu LJ, El-Sakkary N, Skinner DE, Ekins S, Caffrey CR. PMID: 33434015; PMCID: PMC7887754.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    4. Congeners Derived from Microtubule-Active Phenylpyrimidines Produce a Potent and Long-Lasting Paralysis of Schistosoma mansoni In Vitro. ACS Infect Dis. 2021 05 14; 7(5):1089-1103. Monti L, Cornec AS, Oukoloff K, Kovalevich J, Prijs K, Alle T, Brunden KR, Smith AB, El-Sakkary N, Liu LJ, Syed A, Skinner DE, Ballatore C, Caffrey CR. PMID: 33135408.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    5. Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone. J Antimicrob Chemother. 2020 10 01; 75(10):2925-2932. Probst A, Häberli C, Siegel D, Huang J, Vigneron S, Ta AP, Skinner DE, El-Sakkary N, Momper JD, Gangoiti J, Dong Y, Vennerstrom JL, Charman SA, Caffrey CR, Keiser J. PMID: 32617557; PMCID: PMC7556815.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    6. Synthesis and Bioactivity of Phthalimide Analogs as Potential Drugs to Treat Schistosomiasis, a Neglected Disease of Poverty. Pharmaceuticals (Basel). 2020 02 03; 13(2). Singh S, El-Sakkary N, Skinner DE, Sharma PP, Ottilie S, Antonova-Koch Y, Kumar P, Winzeler E, Caffrey CR, Rathi B. PMID: 32028743; PMCID: PMC7169845.
      View in: PubMed   Mentions:
    7. Structure-Bioactivity Relationships of Lapatinib Derived Analogs against Schistosoma mansoni. ACS Med Chem Lett. 2020 Mar 12; 11(3):258-265. Buskes MJ, Clements M, Bachovchin KA, Jalani HB, Leonard A, Bag S, Klug DM, Singh B, Campbell RF, Sciotti RJ, El-Sakkary N, Caffrey CR, Pollastri MP, Ferrins L. PMID: 32184954; PMCID: PMC7073886.
      View in: PubMed   Mentions: 1  
    8. The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni. ACS Infect Dis. 2019 10 11; 5(10):1802-1812. Bibo-Verdugo B, Wang SC, Almaliti J, Ta AP, Jiang Z, Wong DA, Lietz CB, Suzuki BM, El-Sakkary N, Hook V, Salvesen GS, Gerwick WH, Caffrey CR, O'Donoghue AJ. PMID: 31355632; PMCID: PMC7283364.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    9. Bioactivity of Farnesyltransferase Inhibitors Against Entamoeba histolytica and Schistosoma mansoni. Front Cell Infect Microbiol. 2019; 9:180. Probst A, Nguyen TN, El-Sakkary N, Skinner D, Suzuki BM, Buckner FS, Gelb MH, Caffrey CR, Debnath A. PMID: 31192168; PMCID: PMC6548881.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    10. Octopamine signaling in the metazoan pathogen Schistosoma mansoni: localization, small-molecule screening and opportunities for drug development. Dis Model Mech. 2018 07 30; 11(7). El-Sakkary N, Chen S, Arkin MR, Caffrey CR, Ribeiro P. PMID: 29925529; PMCID: PMC6078403.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    11. Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target. PLoS Negl Trop Dis. 2017 Jul; 11(7):e0005680. Long T, Rojo-Arreola L, Shi D, El-Sakkary N, Jarnagin K, Rock F, Meewan M, Rascón AA, Lin L, Cunningham KA, Lemieux GA, Podust L, Abagyan R, Ashrafi K, McKerrow JH, Caffrey CR. PMID: 28704396; PMCID: PMC5526615.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    12. Biogenic amines and the control of neuromuscular signaling in schistosomes. Invert Neurosci. 2012 Jun; 12(1):13-28. Ribeiro P, Gupta V, El-Sakkary N. PMID: 22526557.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    13. A novel G protein-coupled receptor of Schistosoma mansoni (SmGPR-3) is activated by dopamine and is widely expressed in the nervous system. PLoS Negl Trop Dis. 2012; 6(2):e1523. El-Shehabi F, Taman A, Moali LS, El-Sakkary N, Ribeiro P. PMID: 22389736; PMCID: PMC3289605.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
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