Nelly El-sakkary

Title(s)	Postdoctoral Scholar, School of Pharmacy and Pharmaceutical Science
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation. Eur J Med Chem. 2021 Sep 10; 226:113823. Padalino G, El-Sakkary N, Liu LJ, Liu C, Harte DSG, Barnes RE, Sayers E, Forde-Thomas J, Whiteland H, Bassetto M, Ferla S, Johnson G, Jones AT, Caffrey CR, Chalmers I, Brancale A, Hoffmann KF. PMID: 34536671.

View in: PubMed Mentions: Fields:
Che Chemistry
Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis. J Med Chem. 2021 07 08; 64(13):9404-9430. Klug DM, Mavrogiannaki EM, Forbes KC, Silva L, Diaz-Gonzalez R, Pérez-Moreno G, Ceballos-Pérez G, Garcia-Hernández R, Bosch-Navarrete C, Cordón-Obras C, Gómez-Liñán C, Saura A, Momper JD, Martinez-Martinez MS, Manzano P, Syed A, El-Sakkary N, Caffrey CR, Gamarro F, Ruiz-Perez LM, Gonzalez Pacanowska D, Ferrins L, Navarro M, Pollastri MP. PMID: 34156862; PMCID: PMC8412142.

View in: PubMed Mentions: Fields:
Che Chemistry
Translation:Humans Animals Cells
A Machine Learning Strategy for Drug Discovery Identifies Anti-Schistosomal Small Molecules. ACS Infect Dis. 2021 02 12; 7(2):406-420. Zorn KM, Sun S, McConnon CL, Ma K, Chen EK, Foil DH, Lane TR, Liu LJ, El-Sakkary N, Skinner DE, Ekins S, Caffrey CR. PMID: 33434015; PMCID: PMC7887754.

View in: PubMed Mentions: 2 Fields:
Ant Anti-Infective Agents Dru Drug Therapy Mic Microbiology
Translation:Animals
Congeners Derived from Microtubule-Active Phenylpyrimidines Produce a Potent and Long-Lasting Paralysis of Schistosoma mansoni In Vitro. ACS Infect Dis. 2021 05 14; 7(5):1089-1103. Monti L, Cornec AS, Oukoloff K, Kovalevich J, Prijs K, Alle T, Brunden KR, Smith AB, El-Sakkary N, Liu LJ, Syed A, Skinner DE, Ballatore C, Caffrey CR. PMID: 33135408.

View in: PubMed Mentions: 2 Fields:
Ant Anti-Infective Agents Dru Drug Therapy Mic Microbiology
Translation:Humans Animals Cells
Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone. J Antimicrob Chemother. 2020 10 01; 75(10):2925-2932. Probst A, Häberli C, Siegel D, Huang J, Vigneron S, Ta AP, Skinner DE, El-Sakkary N, Momper JD, Gangoiti J, Dong Y, Vennerstrom JL, Charman SA, Caffrey CR, Keiser J. PMID: 32617557; PMCID: PMC7556815.

View in: PubMed Mentions: 1 Fields:
Ant Anti-Infective Agents
Translation:Animals
Synthesis and Bioactivity of Phthalimide Analogs as Potential Drugs to Treat Schistosomiasis, a Neglected Disease of Poverty. Pharmaceuticals (Basel). 2020 02 03; 13(2). Singh S, El-Sakkary N, Skinner DE, Sharma PP, Ottilie S, Antonova-Koch Y, Kumar P, Winzeler E, Caffrey CR, Rathi B. PMID: 32028743; PMCID: PMC7169845.

View in: PubMed Mentions:
Structure-Bioactivity Relationships of Lapatinib Derived Analogs against Schistosoma mansoni. ACS Med Chem Lett. 2020 Mar 12; 11(3):258-265. Buskes MJ, Clements M, Bachovchin KA, Jalani HB, Leonard A, Bag S, Klug DM, Singh B, Campbell RF, Sciotti RJ, El-Sakkary N, Caffrey CR, Pollastri MP, Ferrins L. PMID: 32184954; PMCID: PMC7073886.

View in: PubMed Mentions: 1
The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni. ACS Infect Dis. 2019 10 11; 5(10):1802-1812. Bibo-Verdugo B, Wang SC, Almaliti J, Ta AP, Jiang Z, Wong DA, Lietz CB, Suzuki BM, El-Sakkary N, Hook V, Salvesen GS, Gerwick WH, Caffrey CR, O'Donoghue AJ. PMID: 31355632; PMCID: PMC7283364.

View in: PubMed Mentions: 8 Fields:
Ant Anti-Infective Agents Dru Drug Therapy Mic Microbiology
Translation:Humans Animals Cells
Bioactivity of Farnesyltransferase Inhibitors Against Entamoeba histolytica and Schistosoma mansoni. Front Cell Infect Microbiol. 2019; 9:180. Probst A, Nguyen TN, El-Sakkary N, Skinner D, Suzuki BM, Buckner FS, Gelb MH, Caffrey CR, Debnath A. PMID: 31192168; PMCID: PMC6548881.

View in: PubMed Mentions: 5 Fields:
Cel Cell Biology Com Communicable Diseases Mic Microbiology
Translation:Animals
Octopamine signaling in the metazoan pathogen Schistosoma mansoni: localization, small-molecule screening and opportunities for drug development. Dis Model Mech. 2018 07 30; 11(7). El-Sakkary N, Chen S, Arkin MR, Caffrey CR, Ribeiro P. PMID: 29925529; PMCID: PMC6078403.

View in: PubMed Mentions: 2 Fields:
Med Medicine (General)
Translation:Animals Cells
Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target. PLoS Negl Trop Dis. 2017 Jul; 11(7):e0005680. Long T, Rojo-Arreola L, Shi D, El-Sakkary N, Jarnagin K, Rock F, Meewan M, Rascón AA, Lin L, Cunningham KA, Lemieux GA, Podust L, Abagyan R, Ashrafi K, McKerrow JH, Caffrey CR. PMID: 28704396; PMCID: PMC5526615.

View in: PubMed Mentions: 11 Fields:
Tro Tropical Medicine
Translation:Animals Cells
Biogenic amines and the control of neuromuscular signaling in schistosomes. Invert Neurosci. 2012 Jun; 12(1):13-28. Ribeiro P, Gupta V, El-Sakkary N. PMID: 22526557.

View in: PubMed Mentions: 9 Fields:
Neu Neurology
Translation:Animals Cells
A novel G protein-coupled receptor of Schistosoma mansoni (SmGPR-3) is activated by dopamine and is widely expressed in the nervous system. PLoS Negl Trop Dis. 2012; 6(2):e1523. El-Shehabi F, Taman A, Moali LS, El-Sakkary N, Ribeiro P. PMID: 22389736; PMCID: PMC3289605.

View in: PubMed Mentions: 20 Fields:
Tro Tropical Medicine
Translation:Animals Cells