Navtej Toor

Title(s)Associate Professor, Chemistry and Biochemistry
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Structural Biology of Retrotransposition and pre-mRNA Splicing
    NIH R35GM141706Apr 1, 2021 - Mar 31, 2026
    Role: Principal Investigator
    Structural Biology of Retrotransposition
    NIH R01GM123275Sep 1, 2017 - Aug 31, 2021
    Role: Principal Investigator
    Structural Biology of RNA Splicing
    NIH R01GM102216Jul 16, 2012 - May 31, 2018
    Role: Principal Investigator
    An Undulator Resource for Structural Biology
    NIH P41RR015301Jun 15, 2001 - Mar 31, 2013
    Role: Co-Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Structural evidence for metal ion catalysis in the ribosome. bioRxiv. 2025 May 17. Hingey JM, Rudolfs B, Haack DB, Murphy FV, Joseph S, Toor N. PMID: 40463213; PMCID: PMC12132363.
      View in: PubMed   Mentions:
    2. Ensemble refinement of mismodeled cryo-EM RNA structures using all-atom simulations. Nat Commun. 2025 May 16; 16(1):4549. Posani E, Janoš P, Haack D, Toor N, Bonomi M, Magistrato A, Bussi G. PMID: 40379699; PMCID: PMC12084557.
      View in: PubMed   Mentions:    Fields:    
    3. Scaffold-enabled high-resolution cryo-EM structure determination of RNA. Nat Commun. 2025 Jan 21; 16(1):880. Haack DB, Rudolfs B, Jin S, Khitun A, Weeks KM, Toor N. PMID: 39837824; PMCID: PMC11751092.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    4. Scaffold-enabled high-resolution cryo-EM structure determination of RNA. bioRxiv. 2024 Jun 10. Haack DB, Rudolfs B, Jin S, Weeks KM, Toor N. PMID: 38915706; PMCID: PMC11195047.
      View in: PubMed   Mentions:
    5. Structural basis of branching during RNA splicing. Nat Struct Mol Biol. 2024 Jan; 31(1):179-189. Haack DB, Rudolfs B, Zhang C, Lyumkis D, Toor N. PMID: 38057551; PMCID: PMC10968580.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    6. Fluorescent labeling of RNA and DNA on the Hoogsteen edge using sulfinate chemistry. RNA. 2023 09; 29(9):1437-1451. Bassi T, Hirlinger A, Grayson L, Vantourout J, Toor N. PMID: 37277186; PMCID: PMC10573292.
      View in: PubMed   Mentions:    Fields:    
    7. Recognition of transcription terminators during retrotransposition: How to keep a group II intron quiet. Mol Cell. 2023 02 02; 83(3):332-334. Haack DB, Toor N. PMID: 36736308.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    8. Recent advances in the structural biology of encapsulin bacterial nanocompartments. J Struct Biol X. 2022; 6:100062. Wiryaman T, Toor N. PMID: 35146412; PMCID: PMC8802124.
      View in: PubMed   Mentions: 7  
    9. Cryo-EM structure of a thermostable bacterial nanocompartment. IUCrJ. 2021 May 01; 8(Pt 3):342-350. Wiryaman T, Toor N. PMID: 33953921; PMCID: PMC8086157.
      View in: PubMed   Mentions: 14     Fields:    
    10. SHAPE Profiling to Probe Group II Intron Conformational Dynamics During Splicing. Methods Mol Biol. 2021; 2167:171-182. Wiryaman T, Toor N. PMID: 32712920; PMCID: PMC7510887.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    11. Retroelement origins of pre-mRNA splicing. Wiley Interdiscip Rev RNA. 2020 07; 11(4):e1589. Haack DB, Toor N. PMID: 32045511; PMCID: PMC7340585.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    12. Cryo-EM Structures of a Group II Intron Reverse Splicing into DNA. Cell. 2019 07 25; 178(3):612-623.e12. Haack DB, Yan X, Zhang C, Hingey J, Lyumkis D, Baker TS, Toor N. PMID: 31348888; PMCID: PMC6662634.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    13. Structural basis for the second step of group II intron splicing. Nat Commun. 2018 Nov 08; 9(1):4676. Chan RT, Peters JK, Robart AR, Wiryaman T, Rajashankar KR, Toor N. PMID: 30410046; PMCID: PMC6224600.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    14. Selecting New RNA Crystal Contacts. Structure. 2018 09 04; 26(9):1166-1167. Gomez A, Toor N. PMID: 30184479; PMCID: PMC6690054.
      View in: PubMed   Mentions: 4     Fields:    
    15. Molecular Mechanism and Evolution of Nuclear Pre-mRNA and Group II Intron Splicing: Insights from Cryo-Electron Microscopy Structures. Chem Rev. 2018 04 25; 118(8):4156-4176. Galej WP, Toor N, Newman AJ, Nagai K. PMID: 29377672.
      View in: PubMed   Mentions: 26     Fields:    
    16. Structure determination of group II introns. Methods. 2017 Aug 01; 125:10-15. Wiryaman T, Toor N. PMID: 28648679; PMCID: PMC5678935.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    17. Identification of a GUAAY Pentaloop Sequence Involved in a Novel RNA Loop-Helix Interaction. J Mol Biol. 2016 Dec 04; 428(24 Pt B):4882-4889. Chan RT, Keating KS, Go MC, Toor N. PMID: 27771480; PMCID: PMC5138090.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    18. Group II intron lariat: Structural insights into the spliceosome. RNA Biol. 2015; 12(9):913-7. Peters JK, Toor N. PMID: 26121424; PMCID: PMC4615233.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    19. Crystal structure of a eukaryotic group II intron lariat. Nature. 2014 Oct 09; 514(7521):193-7. Robart AR, Chan RT, Peters JK, Rajashankar KR, Toor N. PMID: 25252982; PMCID: PMC4197185.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    20. Crystal structure of a group II intron in the pre-catalytic state. Nat Struct Mol Biol. 2012 Apr 08; 19(5):555-7. Chan RT, Robart AR, Rajashankar KR, Pyle AM, Toor N. PMID: 22484319; PMCID: PMC3670821.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    21. Tertiary architecture of the Oceanobacillus iheyensis group II intron. RNA. 2010 Jan; 16(1):57-69. Toor N, Keating KS, Fedorova O, Rajashankar K, Wang J, Pyle AM. PMID: 19952115; PMCID: PMC2802037.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    22. A structural analysis of the group II intron active site and implications for the spliceosome. RNA. 2010 Jan; 16(1):1-9. Keating KS, Toor N, Perlman PS, Pyle AM. PMID: 19948765; PMCID: PMC2802019.
      View in: PubMed   Mentions: 65     Fields:    Translation:Cells
    23. Structural insights into RNA splicing. Curr Opin Struct Biol. 2009 Jun; 19(3):260-6. Toor N, Keating KS, Pyle AM. PMID: 19443210; PMCID: PMC2756803.
      View in: PubMed   Mentions: 26     Fields:    
    24. Structural basis for exon recognition by a group II intron. Nat Struct Mol Biol. 2008 Nov; 15(11):1221-2. Toor N, Rajashankar K, Keating KS, Pyle AM. PMID: 18953333; PMCID: PMC2735234.
      View in: PubMed   Mentions: 35     Fields:    
    25. The GANC tetraloop: a novel motif in the group IIC intron structure. J Mol Biol. 2008 Nov 14; 383(3):475-81. Keating KS, Toor N, Pyle AM. PMID: 18773908; PMCID: PMC2574657.
      View in: PubMed   Mentions: 20     Fields:    
    26. Crystal structure of a self-spliced group II intron. Science. 2008 Apr 04; 320(5872):77-82. Toor N, Keating KS, Taylor SD, Pyle AM. PMID: 18388288; PMCID: PMC4406475.
      View in: PubMed   Mentions: 225     Fields:    Translation:Cells
    27. Self-splicing of a group IIC intron: 5' exon recognition and alternative 5' splicing events implicate the stem-loop motif of a transcriptional terminator. Nucleic Acids Res. 2006; 34(22):6461-71. Toor N, Robart AR, Christianson J, Zimmerly S. PMID: 17130159; PMCID: PMC1702495.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    28. Database for mobile group II introns. Nucleic Acids Res. 2003 Jan 01; 31(1):424-6. Dai L, Toor N, Olson R, Keeping A, Zimmerly S. PMID: 12520040; PMCID: PMC165496.
      View in: PubMed   Mentions: 58     Fields:    Translation:Cells
    29. Identification of a family of group II introns encoding LAGLIDADG ORFs typical of group I introns. RNA. 2002 Nov; 8(11):1373-7. Toor N, Zimmerly S. PMID: 12458791; PMCID: PMC1370344.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
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