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Monte Buchsbaum

Title(s)Emeritus Professor, Psychiatry
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Biography

    Monte S. Buchsbaum, MD, has joined the faculty of the University of California, San Diego as Distinguished Professor of Psychiatry and Radiology. He heads the new NeuroPET Center and leads an effort in developing an expanded research effort with positron emission tomography. Located in Sorrento Valley about 2 miles north of the main campus at 11388 Sorrento Valley Road and close to the UCSD MRI and MEG facilities, the Center will be capable of metabolic studies with fluorodeoxyglucose, and initial radioligand studies of the serotonin transporter with DASB, brain amyloid with PIB, and the dopamine receptor with fallypride for cortical and thalamic receptors and raclopride for striatal receptors. An expanded on-site radiochemistry facility will developed a repertoire of molecular probes for imaging. Coordination with MRI for anatomical analysis of images will be a central feature.

    Dr. Buchsbaum was previously Director of the Neuroscience PET Laboratory at Mt. Sinai Hospital in New York City, has been a pioneer in brain-mapping studies of schizophrenia, both with topographic EEG and PET explorations of antipsychotic-drug effects and the role of the prefrontal cortex and attention in this complex disorder. Since 1980, the primary focus of Dr. Buchsbaum's research has been brain imaging, combining positron emission tomography, computerized EEG and evoked potential brain mapping, and later magnetic resonance imaging and diffusion tensor imaging. While in the Intramural Research Program at the National Institute of Mental Health, Dr. Buchsbaum published some of the first PET studies in psychiatry. In 1982, Dr. Buchsbaum left the NIMH to head the Brain Imaging Center at the University of California, Irvine (UCI) and carried out studies on the prefrontal cortex in schizophrenia using FDG-PET and EEG. In 1992, Dr. Buchsbaum moved to New York to head the Neuroscience PET laboratory, focusing on pharmacological response and PET-FDG. In 1998 he published the first report on diffusion tensor imaging in schizophrenia, extending his work on potential deficits in the prefrontal cortex in schizophrenia. He is Editor of Psychiatry Research and Co-Editor of Psychiatry Research: Neuroimaging. He has published over 500 research reports in scientific journals, the majority on positron emission tomography. He is included in the Institute of Scientific Information data base as one of the most highly-cited scientists (ISIHighlyCited.com).

    Collapse Research 
    Collapse Research Activities and Funding
    PET Imaging of OFC and Amygdala in Panic Disorder
    NIH R01MH071827Apr 15, 2006 - Mar 31, 2009
    Role: Principal Investigator
    M-CPP PET Scanning of Alcoholism:Effects of Sertraline
    NIH R01AA013164Sep 26, 2002 - Jun 30, 2008
    Role: Principal Investigator
    Anatomy and Function of the Thalamus in Schizophrenia
    NIH R01MH060023Aug 1, 1999 - Mar 31, 2009
    Role: Principal Investigator
    NORMAL METABOLISM AND ANATOMY OF BASAL FOREBRAIN IN MAN
    NIH R01MH056489May 1, 1998 - Feb 28, 2002
    Role: Principal Investigator
    SERTRALINE AND NALTREXONE FOR ALCOHOL DEPENDENTS
    NIH R01AA011222Sep 1, 1997 - Aug 31, 2003
    Role: Principal Investigator
    ASIP-UNIVERSITY OF CALIFORNIA-IRVINE
    NIH S15MH045868Sep 1, 1989 - Aug 31, 1990
    Role: Principal Investigator
    PET IMAGING OF PERFORMANCE TASK IN SCHIZOPHRENIA
    NIH R01MH043229Aug 1, 1988 - Jan 31, 1992
    Role: Principal Investigator
    PET STUDIES OF SLEEP IN AFFECTIVE DISORDERS
    NIH R01MH041282Mar 15, 1987 - Apr 30, 1992
    Role: Principal Investigator
    PET STUDIES OF ATTENTION IN SCHIZOPHRENIA
    NIH R01MH040071Mar 1, 1986 - Jun 30, 1997
    Role: Principal Investigator