Michael Mante

Title(s)Staff Res Assoc , Neurosciences
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Preclinical validation of a potent γ-secretase modulator for Alzheimer's disease prevention. J Exp Med. 2021 04 05; 218(4). Rynearson KD, Ponnusamy M, Prikhodko O, Xie Y, Zhang C, Nguyen P, Hug B, Sawa M, Becker A, Spencer B, Florio J, Mante M, Salehi B, Arias C, Galasko D, Head BP, Johnson G, Lin JH, Duddy SK, Rissman RA, Mobley WC, Thinakaran G, Tanzi RE, Wagner SL. PMID: 33651103; PMCID: PMC7931646.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    2. Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2. Neurobiol Dis. 2021 05; 152:105277. Ngolab J, Canchi S, Rasool S, Elmaarouf A, Thomas K, Sarsoza F, Grundman J, Mante M, Florio J, Nandankar N, Korouri S, Zago W, Masliah E, Rissman RA. PMID: 33516874; PMCID: PMC8373010.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    3. Correction to: Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology. Acta Neuropathol Commun. 2020 08 04; 8(1):123. Ngolab J, Trinh I, Rockenstein E, Mante M, Florio J, Trejo M, Masliah D, Adame A, Masliah E, Rissman RA. PMID: 32753049; PMCID: PMC7405419.
      View in: PubMed   Mentions: 2     Fields:    
    4. Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease. Neurobiol Dis. 2019 07; 127:163-177. Spencer B, Trinh I, Rockenstein E, Mante M, Florio J, Adame A, El-Agnaf OMA, Kim C, Masliah E, Rissman RA. PMID: 30849508; PMCID: PMC6588505.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    5. Extracellular Vesicles Isolated from Familial Alzheimer's Disease Neuronal Cultures Induce Aberrant Tau Phosphorylation in the Wild-Type Mouse Brain. J Alzheimers Dis. 2019; 72(2):575-585. Aulston B, Liu Q, Mante M, Florio J, Rissman RA, Yuan SH. PMID: 31594233; PMCID: PMC8373022.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    6. Selective targeting of 3 repeat Tau with brain penetrating single chain antibodies for the treatment of neurodegenerative disorders. Acta Neuropathol. 2018 07; 136(1):69-87. Spencer B, Brüschweiler S, Sealey-Cardona M, Rockenstein E, Adame A, Florio J, Mante M, Trinh I, Rissman RA, Konrat R, Masliah E. PMID: 29934874; PMCID: PMC6112111.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    7. Increased Vulnerability of the Hippocampus in Transgenic Mice Overexpressing APP and Triple Repeat Tau. J Alzheimers Dis. 2018; 61(3):1201-1219. Arner A, Rockenstein E, Mante M, Florio J, Masliah D, Salehi B, Adame A, Overk C, Masliah E, Rissman RA. PMID: 29332037; PMCID: PMC6508863.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    8. Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies. J Neurosci. 2018 01 24; 38(4):1000-1014. Rockenstein E, Ostroff G, Dikengil F, Rus F, Mante M, Florio J, Adame A, Trinh I, Kim C, Overk C, Masliah E, Rissman RA. PMID: 29246926; PMCID: PMC5783958.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    9. MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System Atrophy. Front Mol Neurosci. 2017; 10:329. Valera E, Spencer B, Mott J, Trejo M, Adame A, Mante M, Rockenstein E, Troncoso JC, Beach TG, Masliah E, Desplats P. PMID: 29089869; PMCID: PMC5650998.
      View in: PubMed   Mentions: 30  
    10. Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology. Acta Neuropathol Commun. 2017 06 09; 5(1):46. Ngolab J, Trinh I, Rockenstein E, Mante M, Florio J, Trejo M, Masliah D, Adame A, Masliah E, Rissman RA. PMID: 28599681; PMCID: PMC5466770.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    11. Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy. Acta Neuropathol Commun. 2017 01 13; 5(1):7. Spencer B, Valera E, Rockenstein E, Overk C, Mante M, Adame A, Zago W, Seubert P, Barbour R, Schenk D, Games D, Rissman RA, Masliah E. PMID: 28086964; PMCID: PMC5237270.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    12. Combination of alpha-synuclein immunotherapy with anti-inflammatory treatment in a transgenic mouse model of multiple system atrophy. Acta Neuropathol Commun. 2017 01 05; 5(1):2. Valera E, Spencer B, Fields JA, Trinh I, Adame A, Mante M, Rockenstein E, Desplats P, Masliah E. PMID: 28057080; PMCID: PMC5217191.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    13. Neuropeptide Treatment with Cerebrolysin Enhances the Survival of Grafted Neural Stem Cell in an α-Synuclein Transgenic Model of Parkinson's Disease. J Exp Neurosci. 2015; 9(Suppl 2):131-40. Rockenstein E, Desplats P, Ubhi K, Mante M, Florio J, Adame A, Winter S, Brandstaetter H, Meier D, Moessler H, Masliah E. PMID: 27429559; PMCID: PMC4938121.
      View in: PubMed   Mentions: 3  
    14. α-synuclein conformational antibodies fused to penetratin are effective in models of Lewy body disease. Ann Clin Transl Neurol. 2016 08; 3(8):588-606. Spencer B, Williams S, Rockenstein E, Valera E, Xin W, Mante M, Florio J, Adame A, Masliah E, Sierks MR. PMID: 27606342; PMCID: PMC4999592.
      View in: PubMed   Mentions: 26     Fields:    
    15. Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity. J Neuroinflammation. 2016 05 24; 13(1):120. Fields JA, Overk C, Adame A, Florio J, Mante M, Pineda A, Desplats P, Rockenstein E, Achim C, Masliah E. PMID: 27220536; PMCID: PMC4879748.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    16. Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson's disease. J Neuroinflammation. 2015 Dec 18; 12:236. Kim C, Ojo-Amaize E, Spencer B, Rockenstein E, Mante M, Desplats P, Wrasidlo W, Adame A, Nchekwube E, Oyemade O, Okogun J, Chan M, Cottam H, Masliah E. PMID: 26683203; PMCID: PMC4683943.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    17. Neuroprotective effects of Cerebrolysin in triple repeat Tau transgenic model of Pick's disease and fronto-temporal tauopathies. BMC Neurosci. 2015 Nov 26; 16:85. Rockenstein E, Ubhi K, Mante M, Florio J, Adame A, Winter S, Brandstaetter H, Meier D, Masliah E. PMID: 26611895; PMCID: PMC4662012.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    18. Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson's disease. J Neuroinflammation. 2015 May 14; 12:93. Valera E, Mante M, Anderson S, Rockenstein E, Masliah E. PMID: 25966683; PMCID: PMC4432827.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    19. Neuro-peptide treatment with Cerebrolysin improves the survival of neural stem cell grafts in an APP transgenic model of Alzheimer disease. Stem Cell Res. 2015 Jul; 15(1):54-67. Rockenstein E, Desplats P, Ubhi K, Mante M, Florio J, Adame A, Winter S, Brandstaetter H, Meier D, Masliah E. PMID: 26209890.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    20. A novel triple repeat mutant tau transgenic model that mimics aspects of pick's disease and fronto-temporal tauopathies. PLoS One. 2015; 10(3):e0121570. Rockenstein E, Overk CR, Ubhi K, Mante M, Patrick C, Adame A, Bisquert A, Trejo-Morales M, Spencer B, Masliah E. PMID: 25803611; PMCID: PMC4372415.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    21. Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo. Brain. 2014 May; 137(Pt 5):1496-513. Rockenstein E, Nuber S, Overk CR, Ubhi K, Mante M, Patrick C, Adame A, Trejo-Morales M, Gerez J, Picotti P, Jensen PH, Campioni S, Riek R, Winkler J, Gage FH, Winner B, Masliah E. PMID: 24662516; PMCID: PMC3999721.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansAnimalsCells
    22. Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD. Acta Neuropathol. 2014 Apr; 127(4):477-94. Nuber S, Tadros D, Fields J, Overk CR, Ettle B, Kosberg K, Mante M, Rockenstein E, Trejo M, Masliah E. PMID: 24509835; PMCID: PMC4324760.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    23. Antidepressants reduce neuroinflammatory responses and astroglial alpha-synuclein accumulation in a transgenic mouse model of multiple system atrophy. Glia. 2014 Feb; 62(2):317-37. Valera E, Ubhi K, Mante M, Rockenstein E, Masliah E. PMID: 24310907; PMCID: PMC4183229.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    24. Age-dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: reversal with beclin-1 gene transfer. J Neurovirol. 2013 Feb; 19(1):89-101. Fields J, Dumaop W, Rockenstein E, Mante M, Spencer B, Grant I, Ellis R, Letendre S, Patrick C, Adame A, Masliah E. PMID: 23341224; PMCID: PMC3567331.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimals
    25. Cerebrolysin modulates pronerve growth factor/nerve growth factor ratio and ameliorates the cholinergic deficit in a transgenic model of Alzheimer's disease. J Neurosci Res. 2013 Feb; 91(2):167-77. Ubhi K, Rockenstein E, Vazquez-Roque R, Mante M, Inglis C, Patrick C, Adame A, Fahnestock M, Doppler E, Novak P, Moessler H, Masliah E. PMID: 23152192.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    26. Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson's disease. Mol Neurodegener. 2012 Sep 28; 7:49. Desplats P, Patel P, Kosberg K, Mante M, Patrick C, Rockenstein E, Fujita M, Hashimoto M, Masliah E. PMID: 23017109; PMCID: PMC3502617.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    27. Neuronal to oligodendroglial α-synuclein redistribution in a double transgenic model of multiple system atrophy. Neuroreport. 2012 Mar 07; 23(4):259-64. Rockenstein E, Ubhi K, Inglis C, Mante M, Patrick C, Adame A, Masliah E. PMID: 22314685; PMCID: PMC3289254.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    28. Fluoxetine ameliorates behavioral and neuropathological deficits in a transgenic model mouse of α-synucleinopathy. Exp Neurol. 2012 Apr; 234(2):405-16. Ubhi K, Inglis C, Mante M, Patrick C, Adame A, Spencer B, Rockenstein E, May V, Winkler J, Masliah E. PMID: 22281106; PMCID: PMC3897235.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    29. Beneficial effects of a neurotrophic peptidergic mixture persist for a prolonged period following treatment interruption in a transgenic model of Alzheimer's disease. J Neurosci Res. 2011 Nov; 89(11):1812-21. Rockenstein E, Ubhi K, Pham E, Michael S, Doppler E, Novak P, Inglis C, Mante M, Adame A, Alvarez XA, Moessler H, Masliah E. PMID: 21793038; PMCID: PMC3171597.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    30. Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease. PLoS One. 2011 Apr 29; 6(4):e19338. Masliah E, Rockenstein E, Mante M, Crews L, Spencer B, Adame A, Patrick C, Trejo M, Ubhi K, Rohn TT, Mueller-Steiner S, Seubert P, Barbour R, McConlogue L, Buttini M, Games D, Schenk D. PMID: 21559417; PMCID: PMC3084838.
      View in: PubMed   Mentions: 238     Fields:    Translation:AnimalsCells
    31. Regional comparison of the neurogenic effects of CNTF-derived peptides and cerebrolysin in AβPP transgenic mice. J Alzheimers Dis. 2011; 27(4):743-52. Rockenstein E, Ubhi K, Doppler E, Novak P, Moessler H, Li B, Blanchard J, Grundke-Iqbal I, Iqbal K, Mante M, Adame A, Crews L, Masliah E. PMID: 21860085; PMCID: PMC3925781.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    32. Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors. J Neurosci. 2010 May 05; 30(18):6236-46. Ubhi K, Rockenstein E, Mante M, Inglis C, Adame A, Patrick C, Whitney K, Masliah E. PMID: 20445049; PMCID: PMC2896284.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    33. Alpha-synuclein deficient mice are resistant to toxin-induced multiple system atrophy. Neuroreport. 2010 Apr 21; 21(6):457-62. Ubhi K, Rockenstein E, Mante M, Inglis C, Adame A, Patrick C, Masliah E. PMID: 20224454; PMCID: PMC3049936.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    34. Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alpha-synucleinopathies. Exp Neurol. 2010 Feb; 221(2):267-74. Koob AO, Ubhi K, Paulsson JF, Kelly J, Rockenstein E, Mante M, Adame A, Masliah E. PMID: 19944097; PMCID: PMC2812599.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    35. Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy. J Neurosci Res. 2009 Sep; 87(12):2728-39. Ubhi K, Lee PH, Adame A, Inglis C, Mante M, Rockenstein E, Stefanova N, Wenning GK, Masliah E. PMID: 19405128; PMCID: PMC2885901.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    36. Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin. Acta Neuropathol. 2009 Jun; 117(6):699-712. Ubhi K, Rockenstein E, Doppler E, Mante M, Adame A, Patrick C, Trejo M, Crews L, Paulino A, Moessler H, Masliah E. PMID: 19252918; PMCID: PMC3049872.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    37. Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease. J Neurosci. 2009 Jan 28; 29(4):1115-25. Rose JB, Crews L, Rockenstein E, Adame A, Mante M, Hersh LB, Gage FH, Spencer B, Potkar R, Marr RA, Masliah E. PMID: 19176820; PMCID: PMC2768399.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    38. Rifampicin reduces alpha-synuclein in a transgenic mouse model of multiple system atrophy. Neuroreport. 2008 Aug 27; 19(13):1271-6. Ubhi K, Rockenstein E, Mante M, Patrick C, Adame A, Thukral M, Shults C, Masliah E. PMID: 18695506; PMCID: PMC2885900.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    39. Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation. J Neurosci. 2007 Feb 21; 27(8):1981-91. Rockenstein E, Torrance M, Adame A, Mante M, Bar-on P, Rose JB, Crews L, Masliah E. PMID: 17314294; PMCID: PMC6673566.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsCells
    40. Effects of Cerebrolysin on neurogenesis in an APP transgenic model of Alzheimer's disease. Acta Neuropathol. 2007 Mar; 113(3):265-75. Rockenstein E, Mante M, Adame A, Crews L, Moessler H, Masliah E. PMID: 17131129.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    41. Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease. J Neurosci Res. 2006 May 15; 83(7):1252-61. Rockenstein E, Torrance M, Mante M, Adame A, Paulino A, Rose JB, Crews L, Moessler H, Masliah E. PMID: 16511867.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    42. Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy. J Neurosci. 2005 Nov 16; 25(46):10689-99. Shults CW, Rockenstein E, Crews L, Adame A, Mante M, Larrea G, Hashimoto M, Song D, Iwatsubo T, Tsuboi K, Masliah E. PMID: 16291942; PMCID: PMC6725840.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansAnimalsCells
    43. High beta-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels: implications for the treatment of Alzheimer disease. J Biol Chem. 2005 Sep 23; 280(38):32957-67. Rockenstein E, Mante M, Alford M, Adame A, Crews L, Hashimoto M, Esposito L, Mucke L, Masliah E. PMID: 16027115.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    44. Lysosomal pathology associated with alpha-synuclein accumulation in transgenic models using an eGFP fusion protein. J Neurosci Res. 2005 Apr 15; 80(2):247-59. Rockenstein E, Schwach G, Ingolic E, Adame A, Crews L, Mante M, Pfragner R, Schreiner E, Windisch M, Masliah E. PMID: 15765523.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
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