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Michael Castle

Title(s)Assistant Project Scientist, Neurosciences
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #0626
La Jolla CA 92093
Phone000-000-NULL
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Postmortem Analysis in a Clinical Trial of AAV2-NGF Gene Therapy for Alzheimer's Disease Identifies a Need for Improved Vector Delivery. Hum Gene Ther. 2020 Apr; 31(7-8):415-422. Castle MJ, Baltanás FC, Kovacs I, Nagahara AH, Barba D, Tuszynski MH. PMID: 32126838.
      View in: PubMed   Mentions:    Fields:    
    2. In Situ Hybridization for Detection of AAV-Mediated Gene Expression. Methods Mol Biol. 2019; 1950:107-122. Hunter JE, Gurda BL, Yoon SY, Castle MJ, Wolfe JH. PMID: 30783970.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion. Sci Adv. 2018 11; 4(11):eaau9859. Castle MJ, Cheng Y, Asokan A, Tuszynski MH. PMID: 30443600.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    4. Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids. Methods Mol Biol. 2016; 1382:133-49. Castle MJ, Turunen HT, Vandenberghe LH, Wolfe JH. PMID: 26611584.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    5. Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport. Hum Gene Ther. 2014 Aug; 25(8):705-20. Castle MJ, Gershenson ZT, Giles AR, Holzbaur EL, Wolfe JH. PMID: 24694006.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    6. Long-distance axonal transport of AAV9 is driven by dynein and kinesin-2 and is trafficked in a highly motile Rab7-positive compartment. Mol Ther. 2014 Mar; 22(3):554-566. Castle MJ, Perlson E, Holzbaur EL, Wolfe JH. PMID: 24100640.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    7. Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey. Sci Transl Med. 2011 Jun 22; 3(88):88ra54. Vandenberghe LH, Bell P, Maguire AM, Cearley CN, Xiao R, Calcedo R, Wang L, Castle MJ, Maguire AC, Grant R, Wolfe JH, Wilson JM, Bennett J. PMID: 21697530.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
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