Mei Gao

TitleAssistant Adjunct Professor
InstitutionUniversity of California San Diego
Address9500 Gilman Drive #0912
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Gao M, Lai NC, Giamouridis D, Kim YC, Tan Z, Guo T, Dillmann WH, Suarez J, Hammond HK. Cardiac-Directed Expression of Adenylyl Cyclase Catalytic Domain Reverses Cardiac Dysfunction Caused by Sustained Beta-Adrenergic Receptor Stimulation. JACC Basic Transl Sci. 2016 Dec; 1(7):617-629. PMID: 28670631.
      View in: PubMed
    2. Gao M, Giamouridis D, Lai NC, Walenta E, Paschoal VA, Kim YC, Miyanohara A, Guo T, Liao M, Liu L, Tan Z, Ciaraldi TP, Schenk S, Bhargava A, Oh DY, Hammond HK. One-time injection of AAV8 encoding urocortin 2 provides long-term resolution of insulin resistance. JCI Insight. 2016 Sep 22; 1(15):e88322. PMID: 27699250.
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    3. Hammond HK, Penny WF, Traverse JH, Henry TD, Watkins MW, Yancy CW, Sweis RN, Adler ED, Patel AN, Murray DR, Ross RS, Bhargava V, Maisel A, Barnard DD, Lai NC, Dalton ND, Lee ML, Narayan SM, Blanchard DG, Gao M. Intracoronary Gene Transfer of Adenylyl Cyclase 6 in Patients With Heart Failure: A Randomized Clinical Trial. JAMA Cardiol. 2016 05 01; 1(2):163-71. PMID: 27437887.
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    4. Gao M, Lai NC, Tang T, Guo T, Tang R, Chun BJ, Wang H, Dalton NN, Suarez J, Dillmann WH, Hammond HK. Preserved cardiac function despite marked impairment of cAMP generation. PLoS One. 2013; 8(9):e72151. PMID: 24147149; PMCID: PMC3797917.
    5. Tang T, Lai NC, Wright AT, Gao M, Lee P, Guo T, Tang R, McCulloch AD, Hammond HK. Adenylyl cyclase 6 deletion increases mortality during sustained ß-adrenergic receptor stimulation. J Mol Cell Cardiol. 2013 Jul; 60:60-7. PMID: 23587598.
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    6. Fang H, Lai NC, Gao M, Miyanohara A, Roth DM, Tang T, Hammond HK. Comparison of adeno-associated virus serotypes and delivery methods for cardiac gene transfer. Hum Gene Ther Methods. 2012 Aug; 23(4):234-41. PMID: 22966786; PMCID: PMC3555516.
    7. Lai NC, Gao M, Tang E, Tang R, Guo T, Dalton ND, Deng A, Tang T. Pressure overload-induced cardiac remodeling and dysfunction in the absence of interleukin 6 in mice. Lab Invest. 2012 Nov; 92(11):1518-26. PMID: 22825686; PMCID: PMC3482286.
    8. Tang T, Hammond HK, Firth A, Yang Y, Gao M, Yuan JX, Lai NC. Adenylyl cyclase 6 improves calcium uptake and left ventricular function in aged hearts. J Am Coll Cardiol. 2011 May 03; 57(18):1846-55. PMID: 21527160; PMCID: PMC3087976.
    9. Gao M, Hammond HK. Unanticipated signaling events associated with cardiac adenylyl cyclase gene transfer. J Mol Cell Cardiol. 2011 May; 50(5):751-8. PMID: 21354173; PMCID: PMC3095111.
    10. Gao M, Tang T, Lai NC, Miyanohara A, Guo T, Tang R, Firth AL, Yuan JX, Hammond HK. Beneficial effects of adenylyl cyclase type 6 (AC6) expression persist using a catalytically inactive AC6 mutant. Mol Pharmacol. 2011 Mar; 79(3):381-8. PMID: 21127130; PMCID: PMC3061356.
    11. Tang T, Lai NC, Hammond HK, Roth DM, Yang Y, Guo T, Gao M. Adenylyl cyclase 6 deletion reduces left ventricular hypertrophy, dilation, dysfunction, and fibrosis in pressure-overloaded female mice. J Am Coll Cardiol. 2010 Apr 06; 55(14):1476-86. PMID: 20359598; PMCID: PMC3081694.
    12. Gao M, Tang T, Miyanohara A, Feramisco JR, Hammond HK. beta(1)-Adrenergic receptor vs adenylyl cyclase 6 expression in cardiac myocytes: differences in transgene localization and intracellular signaling. Cell Signal. 2010 Apr; 22(4):584-9. PMID: 19932173; PMCID: PMC2815038.
    13. Gao M, Miyanohara A, Feramisco JR, Tang T. Activation of PH-domain leucine-rich protein phosphatase 2 (PHLPP2) by agonist stimulation in cardiac myocytes expressing adenylyl cyclase type 6. Biochem Biophys Res Commun. 2009 Jun 26; 384(2):193-8. PMID: 19450723; PMCID: PMC2693944.
    14. Tang T, Gao M, Miyanohara A, Hammond HK. Galphaq reduces cAMP production by decreasing Galphas protein abundance. Biochem Biophys Res Commun. 2008 Dec 12; 377(2):679-684. PMID: 18948082; PMCID: PMC2688725.
    15. Gao M, Tang T, Guo T, Miyanohara A, Yajima T, Pestonjamasp K, Feramisco JR, Hammond HK. Adenylyl cyclase type VI increases Akt activity and phospholamban phosphorylation in cardiac myocytes. J Biol Chem. 2008 Nov 28; 283(48):33527-35. PMID: 18838385; PMCID: PMC2586283.
    16. Lai NC, Tang T, Gao M, Saito M, Takahashi T, Roth DM, Hammond HK. Activation of cardiac adenylyl cyclase expression increases function of the failing ischemic heart in mice. J Am Coll Cardiol. 2008 Apr 15; 51(15):1490-7. PMID: 18402905; PMCID: PMC3095112.
    17. Tang T, Gao M, Lai NC, Firth AL, Takahashi T, Guo T, Yuan JX, Roth DM, Hammond HK. Adenylyl cyclase type 6 deletion decreases left ventricular function via impaired calcium handling. Circulation. 2008 Jan 01; 117(1):61-9. PMID: 18071070.
      View in: PubMed
    18. Phan HM, Gao M, Lai NC, Tang T, Hammond HK. New signaling pathways associated with increased cardiac adenylyl cyclase 6 expression: implications for possible congestive heart failure therapy. Trends Cardiovasc Med. 2007 Oct; 17(7):215-21. PMID: 17936202; PMCID: PMC2278010.
    19. Rebolledo B, Lai NC, Gao M, Takahashi T, Roth DM, Baird SM, Hammond HK. Adenylylcyclase gene transfer increases function of the failing heart. Hum Gene Ther. 2006 Oct; 17(10):1043-8. PMID: 17007567.
      View in: PubMed
    20. Tang T, Lai NC, Roth DM, Drumm J, Guo T, Lee KW, Han PL, Dalton N, Gao M. Adenylyl cyclase type V deletion increases basal left ventricular function and reduces left ventricular contractile responsiveness to beta-adrenergic stimulation. Basic Res Cardiol. 2006 Mar; 101(2):117-26. PMID: 16283593.
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    21. Gao M, Lai NC, Hammond HK. Signal peptide increases the efficacy of angiogenic gene transfer for treatment of myocardial ischemia. Hum Gene Ther. 2005 Sep; 16(9):1058-64. PMID: 16149904.
      View in: PubMed
    22. Roth DM, Lai NC, Gao M, Fine S, McKirnan MD, Roth DA, Hammond HK. Nitroprusside increases gene transfer associated with intracoronary delivery of adenovirus. Hum Gene Ther. 2004 Oct; 15(10):989-94. PMID: 15585114.
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    23. Lai NC, Roth DM, Gao M, Tang T, Dalton N, Lai YY, Spellman M, Clopton P, Hammond HK. Intracoronary adenovirus encoding adenylyl cyclase VI increases left ventricular function in heart failure. Circulation. 2004 Jul 20; 110(3):330-6. PMID: 15249510.
      View in: PubMed
    24. Gao M, Tang T, Guo T, Sun SQ, Feramisco JR, Hammond HK. Adenylyl cyclase type VI gene transfer reduces phospholamban expression in cardiac myocytes via activating transcription factor 3. J Biol Chem. 2004 Sep 10; 279(37):38797-802. PMID: 15231818.
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    25. Roth DM, Lai NC, Gao M, Drumm JD, Jimenez J, Feramisco JR, Hammond HK. Indirect intracoronary delivery of adenovirus encoding adenylyl cyclase increases left ventricular contractile function in mice. Am J Physiol Heart Circ Physiol. 2004 Jul; 287(1):H172-7. PMID: 15001445.
      View in: PubMed
    26. Roth DM, Drumm JD, Bhargava V, Swaney JS, Gao M, Hammond HK. Cardiac-directed expression of adenylyl cyclase and heart rate regulation. Basic Res Cardiol. 2003 Nov; 98(6):380-7. PMID: 14556083.
      View in: PubMed