Meghana Pagadala

Title(s)Postdoctoral Scholar, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Germline DNA damage response gene mutations as predictive biomarkers of immune checkpoint inhibitor efficacy. Front Immunol. 2024; 15:1322187. Dennis MJ, Bylsma S, Madlensky L, Pagadala MS, Carter H, Patel SP. PMID: 38348036; PMCID: PMC10859432.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Integrated germline and somatic features reveal divergent immune pathways driving ICB response. bioRxiv. 2024 Jan 15. Sears T, Pagadala M, Castro A, Lee KH, Kong J, Tanaka K, Lippman S, Zanetti M, Carter H. PMID: 38293085; PMCID: PMC10827124.
      View in: PubMed   Mentions:
    3. Genetic risk and likelihood of prostate cancer detection on first biopsy by ancestry. J Natl Cancer Inst. 2024 Jan 11. Lee KM, Nelson T, Bryant A, Teerlink C, Gulati R, Pagadala M, Tcheandjieu C, Pridgen KM, DuVall SL, Yamoah K, Vassy JL, Seibert TM, Hauger R, Rose BS, Lynch JA. PMID: 38212986.
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    4. Comparison of Genomic Inflation Estimates in Genome-Wide Association Studies Using Genetically Identified Ancestry vs Self-Identified Race/Ethnicity in Prostate Cancer Patients in ELLIPSE Cohort. J Urol. 2024 Mar; 211(3):465-468. Pagadala MS, Ryan S, Carter H, Javier-DesLoges J. PMID: 38010907.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma. Nat Genet. 2023 Dec; 55(12):2189-2199. Chapman OS, Luebeck J, Sridhar S, Wong IT, Dixit D, Wang S, Prasad G, Rajkumar U, Pagadala MS, Larson JD, He BJ, Hung KL, Lange JT, Dehkordi SR, Chandran S, Adam M, Morgan L, Wani S, Tiwari A, Guccione C, Lin Y, Dutta A, Lo YY, Juarez E, Robinson JT, Korshunov A, Michaels JA, Cho YJ, Malicki DM, Coufal NG, Levy ML, Hobbs C, Scheuermann RH, Crawford JR, Pomeroy SL, Rich JN, Zhang X, Chang HY, Dixon JR, Bagchi A, Deshpande AJ, Carter H, Fraenkel E, Mischel PS, Wechsler-Reya RJ, Bafna V, Mesirov JP, Chavez L. PMID: 37945900; PMCID: PMC10703696.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. Prevalence, Morbidity, and Mortality of 1,609 Men with Sex Chromosome Aneuploidy: Results from the Diverse Million Veteran Program Cohort. medRxiv. 2023 Jul 16. Davis SM, Teerlink C, Lynch JA, Gorman BR, Pagadala M, Liu A, Panizzon MS, Merritt VC, Genovese G, Pyarajan S, Ross JL, Hauger RL. PMID: 37502926; PMCID: PMC10371178.
      View in: PubMed   Mentions:
    7. Epigenetic Germline Variants Predict Cancer Prognosis and Risk and Distribute Uniquely in Topologically Associating Domains. bioRxiv. 2023 Jul 07. Goudarzi S, Pagadala M, Klie A, Talwar JV, Carter H. PMID: 37461500; PMCID: PMC10349948.
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    8. Autoimmune alleles at the major histocompatibility locus modify melanoma susceptibility. Am J Hum Genet. 2023 07 06; 110(7):1138-1161. Talwar JV, Laub D, Pagadala MS, Castro A, Lewis M, Luebeck GE, Gorman BR, Pan C, Dong FN, Markianos K, Teerlink CC, Lynch J, Hauger R, Pyarajan S, Tsao PS, Morris GP, Salem RM, Thompson WK, Curtius K, Zanetti M, Carter H. PMID: 37339630; PMCID: PMC10357503.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    9. Agent Orange exposure and prostate cancer risk in the Million Veteran Program. medRxiv. 2023 Jun 16. Lui AJ, Pagadala MS, Zhong AY, Lynch J, Karunamuni R, Lee KM, Plym A, Rose BS, Carter H, Kibel AS, DuVall SL, Gaziano JM, Panizzon MS, Hauger RL, Seibert TM. PMID: 37398205; PMCID: PMC10312838.
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    10. The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure. Nat Immunol. 2023 08; 24(8):1318-1330. Wu VH, Yung BS, Faraji F, Saddawi-Konefka R, Wang Z, Wenzel AT, Song MJ, Pagadala MS, Clubb LM, Chiou J, Sinha S, Matic M, Raimondi F, Hoang TS, Berdeaux R, Vignali DAA, Iglesias-Bartolome R, Carter H, Ruppin E, Mesirov JP, Gutkind JS. PMID: 37308665; PMCID: PMC10735169.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    11. Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response. Nat Commun. 2023 05 12; 14(1):2744. Pagadala M, Sears TJ, Wu VH, Pérez-Guijarro E, Kim H, Castro A, Talwar JV, Gonzalez-Colin C, Cao S, Schmiedel BJ, Goudarzi S, Kirani D, Au J, Zhang T, Landi T, Salem RM, Morris GP, Harismendy O, Patel SP, Alexandrov LB, Mesirov JP, Zanetti M, Day CP, Fan CC, Thompson WK, Merlino G, Gutkind JS, Vijayanand P, Carter H. PMID: 37173324; PMCID: PMC10182072.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    12. 3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma. Nat Commun. 2023 04 21; 14(1):2300. Okonechnikov K, Camgöz A, Chapman O, Wani S, Park DE, Hübner JM, Chakraborty A, Pagadala M, Bump R, Chandran S, Kraft K, Acuna-Hidalgo R, Reid D, Sikkink K, Mauermann M, Juarez EF, Jenseit A, Robinson JT, Pajtler KW, Milde T, Jäger N, Fiesel P, Morgan L, Sridhar S, Coufal NG, Levy M, Malicki D, Hobbs C, Kingsmore S, Nahas S, Snuderl M, Crawford J, Wechsler-Reya RJ, Davidson TB, Cotter J, Michaiel G, Fleischhack G, Mundlos S, Schmitt A, Carter H, Michealraj KA, Kumar SA, Taylor MD, Rich J, Buchholz F, Mesirov JP, Pfister SM, Ay F, Dixon JR, Kool M, Chavez L. PMID: 37085539; PMCID: PMC10121654.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    13. Immune niches in brain metastases contain TCF1+ stem-like T cells, are associated with disease control and are modulated by preoperative SRS. Res Sq. 2023 Mar 23. Jansen CS, Prabhu RS, Pagadala MS, Chappa P, Goyal S, Zhou C, Neill SG, Prokhnevska N, Cardenas M, Hoang KB, Zhong J, Torres M, Logan S, Olson JJ, Nduom EK, Del Balzo L, Patel K, Burri SH, Asher AL, Wilkinson S, Lake R, Higgins KA, Patel P, Dhere V, Sowalsky AG, Khan MK, Kissick H, Buchwald ZS. PMID: 36993444; PMCID: PMC10055679.
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    14. Response to Haiman, Kote-Jarai, Darst et al. J Natl Cancer Inst. 2023 03 09; 115(3):343-344. Seibert TM, Pagadala MS, Lynch J, Karunamuni R, Carter H, Rose BS, Hauger RL. PMID: 36629482; PMCID: PMC9996213.
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    15. Polygenic risk of any, metastatic, and fatal prostate cancer in the Million Veteran Program. J Natl Cancer Inst. 2023 02 08; 115(2):190-199. Pagadala MS, Lynch J, Karunamuni R, Alba PR, Lee KM, Agiri FY, Anglin T, Carter H, Gaziano JM, Jasuja GK, Deka R, Rose BS, Panizzon MS, Hauger RL, Seibert TM. PMID: 36305680; PMCID: PMC9905969.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    16. Accurate genome-wide genotyping from archival tissue to explore the contribution of common genetic variants to pre-cancer outcomes. J Transl Med. 2022 12 27; 20(1):623. Nachmanson D, Pagadala M, Steward J, Cheung C, Bruce LK, Lee NQ, O'Keefe TJ, Lin GY, Hasteh F, Morris GP, Carter H, Harismendy O. PMID: 36575447; PMCID: PMC9793518.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. PRState: Incorporating genetic ancestry in prostate cancer risk scores for men of African ancestry. BMC Cancer. 2022 Dec 09; 22(1):1289. Pagadala MS, Linscott JA, Talwar JV, Seibert TM, Rose B, Lynch J, Panizzon M, Hauger R, Hansen MH, Sammon JD, Hayn MH, Kader K, Carter H, Ryan ST. PMID: 36494783; PMCID: PMC9733391.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. The role of testosterone, the androgen receptor, and hypothalamic-pituitary-gonadal axis in depression in ageing Men. Rev Endocr Metab Disord. 2022 12; 23(6):1259-1273. Hauger RL, Saelzler UG, Pagadala MS, Panizzon MS. PMID: 36418656; PMCID: PMC9789012.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Non-cancer-related pathogenic germline variants and expression consequences in ten-thousand cancer genomes. Genome Med. 2021 09 09; 13(1):147. Wang Z, Fan X, Shen Y, Pagadala MS, Signer R, Cygan KJ, Fairbrother WG, Carter H, Chung WK, Huang KL. PMID: 34503567; PMCID: PMC8431938.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    20. Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response. Cancer Res. 2021 04 01; 81(7):1667-1680. Zhang P, Kitchen-Smith I, Xiong L, Stracquadanio G, Brown K, Richter PH, Wallace MD, Bond E, Sahgal N, Moore S, Nornes S, De Val S, Surakhy M, Sims D, Wang X, Bell DA, Zeron-Medina J, Jiang Y, Ryan AJ, Selfe JL, Shipley J, Kar S, Pharoah PD, Loveday C, Jansen R, Grochola LF, Palles C, Protheroe A, Millar V, Ebner DV, Pagadala M, Blagden SP, Maughan TS, Domingo E, Tomlinson I, Turnbull C, Carter H, Bond GL. PMID: 33558336; PMCID: PMC10266546.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    21. A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence. Br J Cancer. 2020 04; 122(8):1231-1241. Surakhy M, Wallace M, Bond E, Grochola LF, Perez H, Di Giovannantonio M, Zhang P, Malkin D, Carter H, Parise IZS, Zambetti G, Komechen H, Paraizo MM, Pagadala MS, Pinto EM, Lalli E, Figueiredo BC, Bond GL. PMID: 32147670; PMCID: PMC7156685.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    22. Domain-swapped T cell receptors improve the safety of TCR gene therapy. Elife. 2016 11 08; 5. Bethune MT, Gee MH, Bunse M, Lee MS, Gschweng EH, Pagadala MS, Zhou J, Cheng D, Heath JR, Kohn DB, Kuhns MS, Uckert W, Baltimore D. PMID: 27823582; PMCID: PMC5101000.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    23. Osteoclast activated FoxP3+ CD8+ T-cells suppress bone resorption in vitro. PLoS One. 2012; 7(6):e38199. Buchwald ZS, Kiesel JR, DiPaolo R, Pagadala MS, Aurora R. PMID: 22701612; PMCID: PMC3368916.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
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