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    Liang Xu

    TitlePostdoctoral Scholar
    SchoolUniversity of California, San Diego
    DepartmentSchool of Pharmacy and Pharmaceutical Science
    Address9500 Gilman Drive #0625
    CA La Jolla 92093
    Phone858-822-0110
    vCardDownload vCard

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Xu L, Wang W, Gotte D, Yang F, Hare AA, Welch TR, Li BC, Shin JH, Chong J, Strathern JN, Dervan PB, Wang D. RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif. Proc Natl Acad Sci U S A. 2016 Nov 1; 113(44):12426-12431. PMID: 27791148.
        View in: PubMed
      2. Shin JH, Xu L, Wang D. RNA polymerase II acts as a selective sensor for DNA lesions and endogenous DNA modifications. Transcription. 2016 May 26; 7(3):57-62. PMID: 27105138.
        View in: PubMed
      3. Xu L, Wang W, Chong J, Shin JH, Xu J, Wang D. RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications. Crit Rev Biochem Mol Biol. 2015 Nov-Dec; 50(6):503-19. PMID: 26392149.
        View in: PubMed
      4. Wang L, Zhou Y, Xu L, Xiao R, Lu X, Chen L, Chong J, Li H, He C, Fu XD, Wang D. Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex. Nature. 2015 Jul 30; 523(7562):621-5. PMID: 26123024.
        View in: PubMed
      5. Xu L, Wang W, Zhang L, Chong J, Huang X, Wang D. Impact of template backbone heterogeneity on RNA polymerase II transcription. Nucleic Acids Res. 2015 Feb 27; 43(4):2232-41. PMID: 25662224.
        View in: PubMed
      6. Xu L, Chen YC, Chong J, Fin A, McCoy LS, Xu J, Zhang C, Wang D. Pyrene-Based Quantitative Detection of the 5-Formylcytosine Loci Symmetry in the CpG Duplex Content during TET-Dependent Demethylation. Angew Chem Int Ed Engl. 2014 Oct 13; 53(42):11223-7. PMID: 25159856.
        View in: PubMed
      7. Xu L, Zhang L, Chong J, Xu J, Huang X, Wang D. Strand-specific (asymmetric) contribution of phosphodiester linkages on RNA polymerase II transcriptional efficiency and fidelity. Proc Natl Acad Sci U S A. 2014 Aug 12; 111(32):E3269-76. PMID: 25074911.
        View in: PubMed
      8. Xu L, Da L, Plouffe SW, Chong J, Kool E, Wang D. Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis. DNA Repair (Amst). 2014 Jul; 19:71-83. PMID: 24767259.
        View in: PubMed
      9. Xu L, Butler KV, Chong J, Wengel J, Kool ET, Wang D. Dissecting the chemical interactions and substrate structural signatures governing RNA polymerase II trigger loop closure by synthetic nucleic acid analogues. Nucleic Acids Res. 2014 May 1; 42(9):5863-70. PMID: 24692664.
        View in: PubMed
      10. Xu L, Chen YC, Nakajima S, Chong J, Wang L, Lan L, Zhang C, Wang D. A Chemical Probe Targets DNA 5-Formylcytosine Sites and Inhibits TDG Excision, Polymerases Bypass, and Gene Expression. Chem Sci. 2014 Feb 1; 5(2):567-574. PMID: 24883182.
        View in: PubMed
      11. Xu L, Plouffe SW, Chong J, Wengel J, Wang D. A chemical perspective on transcriptional fidelity: dominant contributions of sugar integrity revealed by unlocked nucleic acids. Angew Chem Int Ed Engl. 2013 Nov 18; 52(47):12341-5. PMID: 24167045.
        View in: PubMed
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