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    Leonardo Leon

    TitlePostdoctoral Scholar
    SchoolUniversity of California, San Diego
    DepartmentSchool of Pharmacy and Pharmaceutical Science
    Address9500 Gilman Drive #0758
    CA La Jolla 92093
    Phone858-822-7570
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Hammerling BC, Shires SE, Leon L, Cortez MQ, Gustafsson ÅB. Isolation of Rab5-positive endosomes reveals a new mitochondrial degradation pathway utilized by BNIP3 and Parkin. Small GTPases. 2017 Jul 11; 1-8. PMID: 28696827.
        View in: PubMed
      2. Hammerling BC, Najor RH, Cortez MQ, Shires SE, Leon L, Gonzalez ER, Boassa D, Phan S, Thor A, Jimenez RE, Li H, Kitsis RN, Dorn Ii GW, Sadoshima J, Ellisman MH, Gustafsson ÅB. A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Nat Commun. 2017 Jan 30; 8:14050. PMID: 28134239.
        View in: PubMed
      3. Wu CY, Wang DH, Wang X, Dixon SM, Meng L, Ahadi S, Enter DH, Chen CY, Kato J, Leon L, Ramirez LM, Maeda Y, Reis CF, Ribeiro B, Weems B, Kung HJ, Lam KS. Rapid Discovery of Functional Small Molecule Ligands against Proteomic Targets through Library-Against-Library Screening. ACS Comb Sci. 2016 06 13; 18(6):320-9. PMID: 27053324; PMCID: PMC4908505.
      4. Rowson-Hodel AR, Berg AL, Wald JH, Hatakeyama J, VanderVorst K, Curiel DA, Leon L, Sweeney C, Carraway KL. Hexamethylene amiloride engages a novel reactive oxygen species- and lysosome-dependent programmed necrotic mechanism to selectively target breast cancer cells. Cancer Lett. 2016 May 28; 375(1):62-72. PMID: 26944316.
        View in: PubMed
      5. Leon L, Gustafsson ÅB. Staying young at heart: autophagy and adaptation to cardiac aging. J Mol Cell Cardiol. 2016 Jun; 95:78-85. PMID: 26549356; PMCID: PMC4860161 [Available on 06/01/17].
      6. Wecksler AT, Hwang SH, Wettersten HI, Gilda JE, Patton A, Leon L, Carraway KL, Gomes AV, Baar K, Weiss RH, Hammock BD. Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB. Anticancer Drugs. 2014 Apr; 25(4):433-46. PMID: 24525589; PMCID: PMC3947856.
      7. Leon L, Pasupuleti N, Gorin F, Carraway KL. A cell-permeant amiloride derivative induces caspase-independent, AIF-mediated programmed necrotic death of breast cancer cells. PLoS One. 2013; 8(4):e63038. PMID: 23646172; PMCID: PMC3639988.
      8. Pasupuleti N, Leon L, Carraway KL, Gorin F. 5-Benzylglycinyl-amiloride kills proliferating and nonproliferating malignant glioma cells through caspase-independent necroptosis mediated by apoptosis-inducing factor. J Pharmacol Exp Ther. 2013 Mar; 344(3):600-15. PMID: 23241369; PMCID: PMC3583503.
      9. Harley W, Floyd C, Dunn T, Zhang XD, Chen TY, Hegde M, Palandoken H, Nantz MH, Leon L, Carraway KL, Lyeth B, Gorin FA. Dual inhibition of sodium-mediated proton and calcium efflux triggers non-apoptotic cell death in malignant gliomas. Brain Res. 2010 Dec 02; 1363:159-69. PMID: 20869350; PMCID: PMC2996276.
      10. Leon L, Idangodage H, Wan CP, Weers PM. Apolipophorin III: lipopolysaccharide binding requires helix bundle opening. Biochem Biophys Res Commun. 2006 Oct 06; 348(4):1328-33. PMID: 16919602; PMCID: PMC1851894.
      11. Leon L, Pratt CC, Vasquez LJ, Weers PM. Tyrosine fluorescence analysis of apolipophorin III-lipopolysaccharide interaction. Arch Biochem Biophys. 2006 Aug 01; 452(1):38-45. PMID: 16824478.
        View in: PubMed
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