Lauge Farnaes

Title(s)Associate Physician, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Emergence of an early SARS-CoV-2 epidemic in the United States. Cell. 2021 Sep 16; 184(19):4939-4952.e15. Zeller M, Gangavarapu K, Anderson C, Smither AR, Vanchiere JA, Rose R, Snyder DJ, Dudas G, Watts A, Matteson NL, Robles-Sikisaka R, Marshall M, Feehan AK, Sabino-Santos G, Bell-Kareem AR, Hughes LD, Alkuzweny M, Snarski P, Garcia-Diaz J, Scott RS, Melnik LI, Klitting R, McGraw M, Belda-Ferre P, DeHoff P, Sathe S, Marotz C, Grubaugh ND, Nolan DJ, Drouin AC, Genemaras KJ, Chao K, Topol S, Spencer E, Nicholson L, Aigner S, Yeo GW, Farnaes L, Hobbs CA, Laurent LC, Knight R, Hodcroft EB, Khan K, Fusco DN, Cooper VS, Lemey P, Gardner L, Lamers SL, Kamil JP, Garry RF, Suchard MA, Andersen KG. PMID: 34508652.
      View in: PubMed   Mentions:    Fields:    
    2. Use of Metagenomic Next-Generation Sequencing to Identify Pathogens in Pediatric Osteoarticular Infections. Open Forum Infect Dis. 2021 Jul; 8(7):ofab346. Ramchandar N, Burns J, Coufal NG, Pennock A, Briggs B, Stinnett R, Bradley J, Arnold J, Liu GY, Pring M, Upasani VV, Rickert K, Dimmock D, Chiu C, Farnaes L, Cannavino C. PMID: 34322569.
      View in: PubMed   Mentions:
    3. Clinical application of cell-free next-generation sequencing for infectious diseases at a tertiary children's hospital. BMC Infect Dis. 2021 Jun 11; 21(1):552. Wilke J, Ramchandar N, Cannavino C, Pong A, Tremoulet A, Padua LT, Harvey H, Foley J, Farnaes L, Coufal NG. PMID: 34112116.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Project Baby Bear: Rapid precision care incorporating rWGS in 5 California children's hospitals demonstrates improved clinical outcomes and reduced costs of care. Am J Hum Genet. 2021 07 01; 108(7):1231-1238. Dimmock D, Caylor S, Waldman B, Benson W, Ashburner C, Carmichael JL, Carroll J, Cham E, Chowdhury S, Cleary J, D'Harlingue A, Doshi A, Ellsworth K, Galarreta CI, Hobbs C, Houtchens K, Hunt J, Joe P, Joseph M, Kaplan RH, Kingsmore SF, Knight J, Kochhar A, Kronick RG, Limon J, Martin M, Rauen KA, Schwarz A, Shankar SP, Spicer R, Rojas MA, Vargas-Shiraishi O, Wigby K, Zadeh N, Farnaes L. PMID: 34089648.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Screening for Chemotherapy-induced Peripheral Neuropathy and Utilization of Physical Therapy in Pediatric Patients Receiving Treatment for Hematologic Malignancies. J Pediatr Hematol Oncol. 2021 May 18. Wang CP, Syrkin-Nikolau M, Farnaes L, Shen D, Kanegaye M, Kuo DJ. PMID: 34001791.
      View in: PubMed   Mentions:    Fields:    
    6. Use of Plasma Metagenomic Next-generation Sequencing for Pathogen Identification in Pediatric Endocarditis. Pediatr Infect Dis J. 2021 05 01; 40(5):486-488. To RK, Ramchandar N, Gupta A, Pong A, Cannavino C, Foley J, Farnaes L, Coufal NG. PMID: 33410648.
      View in: PubMed   Mentions:    Fields:    
    7. Detection of Neisseria gonorrhoeae from Joint Aspirate by Metagenomic Sequencing in Disseminated Gonococcal Infection. J Pediatric Infect Dis Soc. 2021 Apr 03; 10(3):367-369. Asmerom B, Drobish I, Winckler B, Chiang L, Farnaes L, Beauchamp-Walters J, Bradley JS, Ramchandar N. PMID: 32964934.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    8. Metagenomic Next-Generation Sequencing for Pathogen Detection and Transcriptomic Analysis in Pediatric Central Nervous System Infections. Open Forum Infect Dis. 2021 Jun; 8(6):ofab104. Ramchandar N, Coufal NG, Warden AS, Briggs B, Schwarz T, Stinnett R, Xie H, Schlaberg R, Foley J, Clarke C, Waldeman B, Enriquez C, Osborne S, Arrieta A, Salyakina D, Janvier M, Sendi P, Totapally BR, Dimmock D, Farnaes L. PMID: 34104666.
      View in: PubMed   Mentions:
    9. Emergence of an early SARS-CoV-2 epidemic in the United States. medRxiv. 2021 Feb 08. Zeller M, Gangavarapu K, Anderson C, Smither AR, Vanchiere JA, Rose R, Dudas G, Snyder DJ, Watts A, Matteson NL, Robles-Sikisaka R, Marshall M, Feehan AK, Sabino-Santos G, Bell-Kareem A, Hughes LD, Alkuzweny M, Snarski P, Garcia-Diaz J, Scott RS, Melnik LI, Klitting R, McGraw M, Belda-Ferre P, DeHoff P, Sathe S, Marotz C, Grubaugh N, Nolan DJ, Drouin AC, Genemaras KJ, Chao K, Topol S, Spencer E, Nicholson L, Aigner S, Yeo GW, Farnaes L, Hobbs CA, Laurent LC, Knight R, Hodcroft EB, Khan K, Fusco DN, Cooper VS, Lemey P, Gardner L, Lamers SL, Kamil JP, Garry RF, Suchard MA, Andersen KG. PMID: 33564781.
      View in: PubMed   Mentions:
    10. Metagenomic sequencing and evaluation of the host response in the pediatric aerodigestive population. Pediatr Pulmonol. 2021 02; 56(2):516-524. Gatcliffe C, Rao A, Brigger M, Dimmock D, Hansen C, Montgomery J, Schlaberg R, Coufal NG, Farnaes L. PMID: 33270378.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. An RCT of Rapid Genomic Sequencing among Seriously Ill Infants Results in High Clinical Utility, Changes in Management, and Low Perceived Harm. Am J Hum Genet. 2020 11 05; 107(5):942-952. Dimmock DP, Clark MM, Gaughran M, Cakici JA, Caylor SA, Clarke C, Feddock M, Chowdhury S, Salz L, Cheung C, Bird LM, Hobbs C, Wigby K, Farnaes L, Bloss CS, Kingsmore SF, RCIGM Investigators . PMID: 33157007.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    12. Diagnosis of cytomegalovirus infection from clinical whole genome sequencing. Sci Rep. 2020 07 03; 10(1):11020. Ramchandar N, Ding Y, Farnaes L, Dimmock D, Hobbs C, Kingsmore SF, Bainbridge M. PMID: 32620939.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Two cases of type-a Haemophilus influenzae meningitis within the same week in the same hospital are phylogenetically unrelated but recently exchanged capsule genes. Microb Genom. 2020 04; 6(4). Terrat Y, Farnaes L, Bradley J, Tromas N, Shapiro BJ. PMID: 32213257.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    14. Management and outcomes of pediatric septic thrombophlebitis: a case series. Pediatr Hematol Oncol. 2020 May; 37(4):344-352. Koo J, Pong A, Dory C, Farnaes L, Thornburg CD. PMID: 32138584.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    15. Rapid Whole Genome Sequencing Has Clinical Utility in Children in the PICU. Pediatr Crit Care Med. 2019 11; 20(11):1007-1020. Sanford EF, Clark MM, Farnaes L, Williams MR, Perry JC, Ingulli EG, Sweeney NM, Doshi A, Gold JJ, Briggs B, Bainbridge MN, Feddock M, Watkins K, Chowdhury S, Nahas SA, Dimmock DP, Kingsmore SF, Coufal NG, RCIGM Investigators . PMID: 31246743.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    16. Biallelic loss of GNAS in a patient with pediatric medulloblastoma. Cold Spring Harb Mol Case Stud. 2019 10; 5(5). Tokita MJ, Nahas S, Briggs B, Malicki DM, Mesirov JP, Reyes IAC, Farnaes L, Levy ML, Kingsmore SF, Dimmock D, Crawford JR, Wechsler-Reya RJ. PMID: 31624069.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Diagnosis and treatment of a boy with IPEX syndrome presenting with diabetes in early infancy. Clin Case Rep. 2019 Nov; 7(11):2123-2127. Kadakia S, Farnaes L, Dimmock D, Chowdhury S, Ding Y, Anderson EJ, Kingsmore S, Newfield RS. PMID: 31788263.
      View in: PubMed   Mentions:
    18. A Randomized, Controlled Trial of the Analytic and Diagnostic Performance of Singleton and Trio, Rapid Genome and Exome Sequencing in Ill Infants. Am J Hum Genet. 2019 10 03; 105(4):719-733. Kingsmore SF, Cakici JA, Clark MM, Gaughran M, Feddock M, Batalov S, Bainbridge MN, Carroll J, Caylor SA, Clarke C, Ding Y, Ellsworth K, Farnaes L, Hildreth A, Hobbs C, James K, Kint CI, Lenberg J, Nahas S, Prince L, Reyes I, Salz L, Sanford E, Schols P, Sweeney N, Tokita M, Veeraraghavan N, Watkins K, Wigby K, Wong T, Chowdhury S, Wright MS, Dimmock D, RCIGM Investigators . PMID: 31564432.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    19. Diagnosis of genetic diseases in seriously ill children by rapid whole-genome sequencing and automated phenotyping and interpretation. Sci Transl Med. 2019 04 24; 11(489). Clark MM, Hildreth A, Batalov S, Ding Y, Chowdhury S, Watkins K, Ellsworth K, Camp B, Kint CI, Yacoubian C, Farnaes L, Bainbridge MN, Beebe C, Braun JJA, Bray M, Carroll J, Cakici JA, Caylor SA, Clarke C, Creed MP, Friedman J, Frith A, Gain R, Gaughran M, George S, Gilmer S, Gleeson J, Gore J, Grunenwald H, Hovey RL, Janes ML, Lin K, McDonagh PD, McBride K, Mulrooney P, Nahas S, Oh D, Oriol A, Puckett L, Rady Z, Reese MG, Ryu J, Salz L, Sanford E, Stewart L, Sweeney N, Tokita M, Van Der Kraan L, White S, Wigby K, Williams B, Wong T, Wright MS, Yamada C, Schols P, Reynders J, Hall K, Dimmock D, Veeraraghavan N, Defay T, Kingsmore SF. PMID: 31019026.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    20. Vaccine Strain Varicella Infection in an Infant With Previously Undiagnosed Perinatal Human Immunodeficiency Type-1 Infection. Pediatr Infect Dis J. 2019 04; 38(4):413-415. Farnaes L, Coufal NG, Spector SA. PMID: 30882735.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    21. Hematologic Manifestations of Nutritional Deficiencies: Early Recognition is Essential to Prevent Serious Complications. J Pediatr Hematol Oncol. 2019 Apr; 41(3):e182-e185. Yu JC, Shliakhtsitsava K, Wang YM, Paul M, Farnaes L, Wong V, Kim J, Thornburg CD. PMID: 30339653.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Community-acquired pneumonia in children: cell-free plasma sequencing for diagnosis and management. Diagn Microbiol Infect Dis. 2019 Jun; 94(2):188-191. Farnaes L, Wilke J, Ryan Loker K, Bradley JS, Cannavino CR, Hong DK, Pong A, Foley J, Coufal NG. PMID: 30819624.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    23. Novel Factor XIII variant identified through whole-genome sequencing in a child with intracranial hemorrhage. Cold Spring Harb Mol Case Stud. 2018 12; 4(6). Briggs B, James KN, Chowdhury S, Thornburg C, Farnaes L, Dimmock D, Kingsmore SF, RCIGM Investigators . PMID: 30404926.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. Concomitant diagnosis of immune deficiency and Pseudomonas sepsis in a 19 month old with ecthyma gangrenosum by host whole-genome sequencing. Cold Spring Harb Mol Case Stud. 2018 12; 4(6). Sanford E, Farnaes L, Batalov S, Bainbridge M, Laubach S, Worthen HM, Tokita M, Kingsmore SF, Bradley J. PMID: 30559311.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    25. Genomic sequencing in acutely ill infants: what will it take to demonstrate clinical value? Genet Med. 2019 02; 21(2):269-271. Grosse SD, Farnaes L. PMID: 30100610.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    26. Rapid Diagnosis of KCNQ2-Associated Early Infantile Epileptic Encephalopathy Improved Outcome. Pediatr Neurol. 2018 09; 86:69-70. Chen DY, Chowdhury S, Farnaes L, Friedman JR, Honold J, Dimmock DP, Gold OBOTRIJJ. PMID: 30107960.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    27. Meta-analysis of the diagnostic and clinical utility of genome and exome sequencing and chromosomal microarray in children with suspected genetic diseases. NPJ Genom Med. 2018; 3:16. Clark MM, Stark Z, Farnaes L, Tan TY, White SM, Dimmock D, Kingsmore SF. PMID: 30002876.
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    28. Rapid whole-genome sequencing identifies a novel AIRE variant associated with autoimmune polyendocrine syndrome type 1. Cold Spring Harb Mol Case Stud. 2018 06; 4(3). Sanford E, Watkins K, Nahas S, Gottschalk M, Coufal NG, Farnaes L, Dimmock D, Kingsmore SF, RCIGM Investigators . PMID: 29437776.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    29. Rapid whole-genome sequencing decreases infant morbidity and cost of hospitalization. NPJ Genom Med. 2018; 3:10. Farnaes L, Hildreth A, Sweeney NM, Clark MM, Chowdhury S, Nahas S, Cakici JA, Benson W, Kaplan RH, Kronick R, Bainbridge MN, Friedman J, Gold JJ, Ding Y, Veeraraghavan N, Dimmock D, Kingsmore SF. PMID: 29644095.
      View in: PubMed   Mentions:
    30. Encephalitis and Thalamic Injury From Neuroinvasive West Nile Virus in Children on Treatment for Acute Lymphoblastic Leukemia. Pediatr Neurol. 2018 03; 80:84-87. Farnaes L, Schiff D, McElroy AK, Coufal NG, Crawford JR, Cannavino C. PMID: 29398166.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    31. Rapid whole-genome sequencing identifies a novel GABRA1 variant associated with West syndrome. Cold Spring Harb Mol Case Stud. 2017 Sep; 3(5). Farnaes L, Nahas SA, Chowdhury S, Nelson J, Batalov S, Dimmock DM, Kingsmore SF, RCIGM Investigators . PMID: 28864462.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    32. Prolonged Antimuscarinic Delirium in a Child Due to Benztropine Exposure Treated With Multiple Doses of Physostigmine. Pediatr Emerg Care. 2016 Apr; 32(4):243-5. Thornton SL, Farnaes L, Minns A. PMID: 26383155.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    33. Recognizing that the microbiome is part of the human immune system will advance treatment of both cancer and infections. J Am Acad Dermatol. 2016 Apr; 74(4):772-4. Gallo RL, Hultsch T, Farnaes L. PMID: 26979362.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    34. Napyradiomycin derivatives, produced by a marine-derived actinomycete, illustrate cytotoxicity by induction of apoptosis. J Nat Prod. 2014 Jan 24; 77(1):15-21. Farnaes L, Coufal NG, Kauffman CA, Rheingold AL, DiPasquale AG, Jensen PR, Fenical W. PMID: 24328269.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    35. Napyradiomycins CNQ525.510B and A80915C target the Hsp90 paralogue Grp94. Org Biomol Chem. 2014 Jan 21; 12(3):418-23. Farnaes L, La Clair JJ, Fenical W. PMID: 24292715.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    36. Bactericidal kinetics of marine-derived napyradiomycins against contemporary methicillin-resistant Staphylococcus aureus. Mar Drugs. 2011; 9(4):680-9. Haste NM, Farnaes L, Perera VR, Fenical W, Nizet V, Hensler ME. PMID: 21731557.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    37. Molecular characterization of the circulating anti-HIV-1 gp120-specific B cell repertoire using antibody phage display libraries generated from pre-selected HIV-1 gp120 binding PBLs. J Immunol Methods. 2005 Feb; 297(1-2):187-201. Koefoed K, Farnaes L, Wang M, Svejgaard A, Burton DR, Ditzel HJ. PMID: 15777942.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    38. Dissecting the cellular functions of annexin XI using recombinant human annexin XI-specific autoantibodies cloned by phage display. J Biol Chem. 2003 Aug 29; 278(35):33120-6. Farnaes L, Ditzel HJ. PMID: 12805373.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    39. A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library. Bioorg Med Chem. 2002 Dec; 10(12):4057-65. Gao C, Mao S, Ditzel HJ, Farnaes L, Wirsching P, Lerner RA, Janda KD. PMID: 12413859.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
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