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Lauge Farnaes

Title(s)Assistant Clinical Professor, Pediatrics
SchoolHealth Sciences
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sanford EF, Clark MM, Farnaes L, Williams MR, Perry JC, Ingulli EG, Sweeney NM, Doshi A, Gold JJ, Briggs B, Bainbridge MN, Feddock M, Watkins K, Chowdhury S, Nahas SA, Dimmock DP, Kingsmore SF, Coufal NG. Rapid Whole Genome Sequencing Has Clinical Utility in Children in the PICU. Pediatr Crit Care Med. 2019 Jun 19. PMID: 31246743.
      View in: PubMed
    2. Clark MM, Hildreth A, Batalov S, Ding Y, Chowdhury S, Watkins K, Ellsworth K, Camp B, Kint CI, Yacoubian C, Farnaes L, Bainbridge MN, Beebe C, Braun JJA, Bray M, Carroll J, Cakici JA, Caylor SA, Clarke C, Creed MP, Friedman J, Frith A, Gain R, Gaughran M, George S, Gilmer S, Gleeson J, Gore J, Grunenwald H, Hovey RL, Janes ML, Lin K, McDonagh PD, McBride K, Mulrooney P, Nahas S, Oh D, Oriol A, Puckett L, Rady Z, Reese MG, Ryu J, Salz L, Sanford E, Stewart L, Sweeney N, Tokita M, Van Der Kraan L, White S, Wigby K, Williams B, Wong T, Wright MS, Yamada C, Schols P, Reynders J, Hall K, Dimmock D, Veeraraghavan N, Defay T, Kingsmore SF. Diagnosis of genetic diseases in seriously ill children by rapid whole-genome sequencing and automated phenotyping and interpretation. Sci Transl Med. 2019 Apr 24; 11(489). PMID: 31019026.
      View in: PubMed
    3. Yu JC, Shliakhtsitsava K, Wang YM, Paul M, Farnaes L, Wong V, Kim J, Thornburg CD. Hematologic Manifestations of Nutritional Deficiencies: Early Recognition is Essential to Prevent Serious Complications. J Pediatr Hematol Oncol. 2019 Apr; 41(3):e182-e185. PMID: 30339653.
      View in: PubMed
    4. Farnaes L, Coufal NG, Spector SA. Vaccine Strain Varicella Infection in an Infant With Previously Undiagnosed Perinatal Human Immunodeficiency Type-1 Infection. Pediatr Infect Dis J. 2019 Apr; 38(4):413-415. PMID: 30882735.
      View in: PubMed
    5. Farnaes L, Wilke J, Ryan Loker K, Bradley JS, Cannavino CR, Hong DK, Pong A, Foley J, Coufal NG. Community-acquired pneumonia in children: cell-free plasma sequencing for diagnosis and management. Diagn Microbiol Infect Dis. 2019 Jun; 94(2):188-191. PMID: 30819624.
      View in: PubMed
    6. Briggs B, James KN, Chowdhury S, Thornburg C, Farnaes L, Dimmock D, Kingsmore SF. Novel Factor XIII variant identified through whole-genome sequencing in a child with intracranial hemorrhage. Cold Spring Harb Mol Case Stud. 2018 Dec; 4(6). PMID: 30404926.
      View in: PubMed
    7. Sanford E, Farnaes L, Batalov S, Bainbridge M, Laubach S, Worthen HM, Tokita M, Kingsmore SF, Bradley J. Concomitant diagnosis of immune deficiency and Pseudomonas sepsis in a 19 month old with ecthyma gangrenosum by host whole-genome sequencing. Cold Spring Harb Mol Case Stud. 2018 Dec; 4(6). PMID: 30559311.
      View in: PubMed
    8. Farnaes L, Coufal N, Spector SA. Vaccine Strain Varicella Infection in an Infant with Previously Undiagnosed Perinatal Human Immunodeficiency Type-1 Infection. Pediatr Infect Dis J. 2018 Sep 07. PMID: 30199479.
      View in: PubMed
    9. Grosse SD, Farnaes L. Genomic sequencing in acutely ill infants: what will it take to demonstrate clinical value? Genet Med. 2019 02; 21(2):269-271. PMID: 30100610.
      View in: PubMed
    10. Chen DY, Chowdhury S, Farnaes L, Friedman JR, Honold J, Dimmock DP, Gold OBOTRIJJ. Rapid Diagnosis of KCNQ2-Associated Early Infantile Epileptic Encephalopathy Improved Outcome. Pediatr Neurol. 2018 Sep; 86:69-70. PMID: 30107960.
      View in: PubMed
    11. Clark MM, Stark Z, Farnaes L, Tan TY, White SM, Dimmock D, Kingsmore SF. Meta-analysis of the diagnostic and clinical utility of genome and exome sequencing and chromosomal microarray in children with suspected genetic diseases. NPJ Genom Med. 2018; 3:16. PMID: 30002876.
      View in: PubMed
    12. Sanford E, Watkins K, Nahas S, Gottschalk M, Coufal NG, Farnaes L, Dimmock D, Kingsmore SF. Rapid whole-genome sequencing identifies a novel AIRE variant associated with autoimmune polyendocrine syndrome type 1. Cold Spring Harb Mol Case Stud. 2018 06; 4(3). PMID: 29437776.
      View in: PubMed
    13. Farnaes L, Hildreth A, Sweeney NM, Clark MM, Chowdhury S, Nahas S, Cakici JA, Benson W, Kaplan RH, Kronick R, Bainbridge MN, Friedman J, Gold JJ, Ding Y, Veeraraghavan N, Dimmock D, Kingsmore SF. Rapid whole-genome sequencing decreases infant morbidity and cost of hospitalization. NPJ Genom Med. 2018; 3:10. PMID: 29644095.
      View in: PubMed
    14. Farnaes L, Schiff D, McElroy AK, Coufal NG, Crawford JR, Cannavino C. Encephalitis and Thalamic Injury From Neuroinvasive West Nile Virus in Children on Treatment for Acute Lymphoblastic Leukemia. Pediatr Neurol. 2018 Mar; 80:84-87. PMID: 29398166.
      View in: PubMed
    15. Farnaes L, Nahas SA, Chowdhury S, Nelson J, Batalov S, Dimmock DM, Kingsmore SF. Rapid whole-genome sequencing identifies a novel GABRA1 variant associated with West syndrome. Cold Spring Harb Mol Case Stud. 2017 Sep; 3(5). PMID: 28864462.
      View in: PubMed
    16. Gallo RL, Hultsch T, Farnaes L. Recognizing that the microbiome is part of the human immune system will advance treatment of both cancer and infections. J Am Acad Dermatol. 2016 Apr; 74(4):772-4. PMID: 26979362.
      View in: PubMed
    17. Thornton SL, Farnaes L, Minns A. Prolonged Antimuscarinic Delirium in a Child Due to Benztropine Exposure Treated With Multiple Doses of Physostigmine. Pediatr Emerg Care. 2016 Apr; 32(4):243-5. PMID: 26383155.
      View in: PubMed
    18. Farnaes L, Coufal NG, Kauffman CA, Rheingold AL, DiPasquale AG, Jensen PR, Fenical W. Napyradiomycin derivatives, produced by a marine-derived actinomycete, illustrate cytotoxicity by induction of apoptosis. J Nat Prod. 2014 Jan 24; 77(1):15-21. PMID: 24328269; PMCID: PMC3913167.
      View in: PubMed, PubMed Central
    19. Farnaes L, La Clair JJ, Fenical W. Napyradiomycins CNQ525.510B and A80915C target the Hsp90 paralogue Grp94. Org Biomol Chem. 2014 Jan 21; 12(3):418-23. PMID: 24292715; PMCID: PMC3893886.
      View in: PubMed, PubMed Central
    20. Haste NM, Farnaes L, Perera VR, Fenical W, Nizet V, Hensler ME. Bactericidal kinetics of marine-derived napyradiomycins against contemporary methicillin-resistant Staphylococcus aureus. Mar Drugs. 2011; 9(4):680-9. PMID: 21731557; PMCID: PMC3124980.
      View in: PubMed, PubMed Central
    21. Koefoed K, Farnaes L, Wang M, Svejgaard A, Burton DR, Ditzel HJ. Molecular characterization of the circulating anti-HIV-1 gp120-specific B cell repertoire using antibody phage display libraries generated from pre-selected HIV-1 gp120 binding PBLs. J Immunol Methods. 2005 Feb; 297(1-2):187-201. PMID: 15777942.
      View in: PubMed
    22. Farnaes L, Ditzel HJ. Dissecting the cellular functions of annexin XI using recombinant human annexin XI-specific autoantibodies cloned by phage display. J Biol Chem. 2003 Aug 29; 278(35):33120-6. PMID: 12805373.
      View in: PubMed
    23. Gao C, Mao S, Ditzel HJ, Farnaes L, Wirsching P, Lerner RA, Janda KD. A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library. Bioorg Med Chem. 2002 Dec; 10(12):4057-65. PMID: 12413859.
      View in: PubMed
    24. Ditzel HJ, Masaki Y, Nielsen H, Farnaes L, Burton DR. Cloning and expression of a novel human antibody-antigen pair associated with Felty's syndrome. Proc Natl Acad Sci U S A. 2000 Aug 01; 97(16):9234-9. PMID: 10922075.
      View in: PubMed
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