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Kyle Spinler

Title(s)Postdoctoral Scholar, Pharmacology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #0695
La Jolla CA 92093
Phone000-000-NULL
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors. Curr Biol. 2017 Jul 24; 27(14):2065-2077.e6. Alvey CM, Spinler KR, Irianto J, Pfeifer CR, Hayes B, Xia Y, Cho S, Dingal PCPD, Hsu J, Smith L, Tewari M, Discher DE. PMID: 28669759.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    2. Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation. Mol Biol Cell. 2017 Jul 07; 28(14):2010-2022. Ivanovska IL, Swift J, Spinler K, Dingal D, Cho S, Discher DE. PMID: 28566555.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    3. Filomicelles from aromatic diblock copolymers increase paclitaxel-induced tumor cell death and aneuploidy compared with aliphatic copolymers. Nanomedicine (Lond). 2016 06; 11(12):1551-69. Nair PR, Karthick SA, Spinler KR, Vakili MR, Lavasanifar A, Discher DE. PMID: 27177319.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    4. Macrophage engulfment of a cell or nanoparticle is regulated by unavoidable opsonization, a species-specific 'Marker of Self' CD47, and target physical properties. Curr Opin Immunol. 2015 Aug; 35:107-12. Sosale NG, Spinler KR, Alvey C, Discher DE. PMID: 26172292.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    5. Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia. Blood. 2015 Jan 15; 125(3):525-33. Spinler KR, Shin JW, Lambert MP, Discher DE. PMID: 25395423.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    6. Matrix elasticity regulates lamin-A,C phosphorylation and turnover with feedback to actomyosin. Curr Biol. 2014 Aug 18; 24(16):1909-17. Buxboim A, Swift J, Irianto J, Spinler KR, Dingal PC, Athirasala A, Kao YR, Cho S, Harada T, Shin JW, Discher DE. PMID: 25127216.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    7. Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival. J Cell Biol. 2014 Mar 03; 204(5):669-82. Harada T, Swift J, Irianto J, Shin JW, Spinler KR, Athirasala A, Diegmiller R, Dingal PC, Ivanovska IL, Discher DE. PMID: 24567359.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansCells
    8. Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells. Cell Stem Cell. 2014 Jan 02; 14(1):81-93. Shin JW, Buxboim A, Spinler KR, Swift J, Christian DA, Hunter CA, Léon C, Gachet C, Dingal PC, Ivanovska IL, Rehfeldt F, Chasis JA, Discher DE. PMID: 24268694.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    9. Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):18892-7. Shin JW, Spinler KR, Swift J, Chasis JA, Mohandas N, Discher DE. PMID: 24191023.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    10. Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science. 2013 Aug 30; 341(6149):1240104. Swift J, Ivanovska IL, Buxboim A, Harada T, Dingal PC, Pinter J, Pajerowski JD, Spinler KR, Shin JW, Tewari M, Rehfeldt F, Speicher DW, Discher DE. PMID: 23990565.
      View in: PubMed   Mentions: 449     Fields:    Translation:HumansAnimalsCells
    11. Mechanobiology of bone marrow stem cells: from myosin-II forces to compliance of matrix and nucleus in cell forms and fates. Differentiation. 2013 Oct; 86(3):77-86. Shin JW, Swift J, Ivanovska I, Spinler KR, Buxboim A, Discher DE. PMID: 23790394.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    12. Dynamic domains in polymersomes: mixtures of polyanionic and neutral diblocks respond more rapidly to changes in calcium than to pH. Langmuir. 2013 Jun 18; 29(24):7499-508. Spinler K, Tian A, Christian DA, Pantano DA, Baumgart T, Discher DE. PMID: 23327600.
      View in: PubMed   Mentions: 5     Fields:    
    13. Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes. Proc Natl Acad Sci U S A. 2011 Jul 12; 108(28):11458-63. Shin JW, Swift J, Spinler KR, Discher DE. PMID: 21709232.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
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