Krishnan Chakravarthy
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Title(s) | Assistant Clinical Professor, Anesthesiology |
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School | Vc-health Sciences-schools |
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Address | 9500 Gilman Drive # La Jolla CA 92093
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vCard | Download vCard |
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Biography Jacobs School of Medicine and Biomedical Sciences , Buffalo, NY | M.D., Ph.D. | 06/2012 | Medicine | Griffin Hospital (Yale Affiliated), Derby, CT | | 07/2013 | Preliminary Medicine | The Johns Hopkins Hospital, Baltimore, MD | | 07/2016 | Anesthesiology | Massachusetts General Hospital/Harvard Medical School , Cambridge, MA | | 07/2017 | Chronic Pain Medicine |
American Society of Pain and Neuroscience | 2019
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| 2020 | American Society of Pain and Neuroscience Young Innovator Award |
Overview Krishnan Chakravarthy, MD, PhD is an assistant clinical professor who specializes in multi-modal pain management. As a pain management specialist, he evaluates, diagnoses and treats all forms of pain.
Dr. Chakravarthy completed sub-specialty fellowship training in pain management at Massachusetts General Hospital/Harvard Medical School and residency training in anesthesiology at The Johns Hopkins Hospital in Baltimore, MD. He interned in general medicine at Griffin Hospital (Yale Affiliate) in Derby, Connecticut. He earned his M.D., Ph.D. degrees at Jacobs School of Medicine and Biomedical Sciences in Buffalo, NY.
Dr. Chakravarthy’s research interests in pain medicine include incorporating new technology into advancing pain care. He is currently focusing on using nanotechnology as an novel system to develop new drug delivery and point of care device platforms to manage chronic pain. Dr. Chakravarthy’s research interests also focus on the effect of anesthetics on host immunity. Prior to joining UCSD he has served as a contractor at the U.S. Centers for Disease Control and Prevention (CDC) where he researched host immunity to influenza virus as a way of developing novel therapeutic and vaccine strategies. His research work has been published in top journals including Anesthesiology, Proceedings of the National Academy of Sciences, and Pain Medicine. His research work has been also featured in Times of India, International Business Times, Futurity, NewsMedical and other national and international venues.
He is also a founder of several biotechnology startup companies in the nanotechnology space, and new drug development focusing on commercializing paradigm-shifting technology in the field of infectious diseases, and chronic pain. He is an active entrepreneur and believes industry plays a critical role in seeing translational science make it to patients.
Dr. Chakravarthy currently serves on the editorial board of several national and international peer reviewed journals, and committees on organizations such as the International Neuromodulation Society.
Notable Honors: American Society of Pain and Neuroscience Young Innovator Award Recipient American Academy of Pain Medicine (AAPM) Pain Medicine Fellowship Excellence Award Recipient, UC San Diego Faculty Nominated for the American Society of Regional Anesthesiology and Pain medicine Resident/Fellow of the year award Griffin Hospital (Yale Affiliated) Intern Physician of the Year Award Recipient Buffalo Business First “Rising Star” University at Buffalo Henry Panasci Technology Entrepreneurship Competition Award Winner National Institute of Health Ruth L. Kirschstein National Research Service Award Recipient
Link to Dr. Chakravarthy’s Laboratory https://www.chakravarthylab.com
Clinical Expertise Areas Anesthesiology, Back Pain, Neck Pain, Complex Regional Pain Syndrome, Interventional Pain Management, Intrathecal pumps, Joint Injection, Post-herpetic Neuralgia, Headache, Phantom Limb Pain, Cancer Pain, Neuromodulation, Spinal Cord Stimulation, Ultrasound Techniques
Research ORNG Applications Bibliographic
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A review of the StimRouter® peripheral neuromodulation system for chronic pain management. Pain Manag. 2020 Dec 09.
Regnier SM, Chen J, Gabriel RA, Chakravarthy KV. PMID: 33291992.
View in: PubMed Mentions: Fields:
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Sensing Evoked Compound Action Potentials from the Spinal Cord: Novel Preclinical and Clinical Considerations for the Pain Management Researcher and Clinician. J Pain Res. 2020; 13:3269-3279.
Chakravarthy K, Bink H, Dinsmoor D. PMID: 33328760.
View in: PubMed Mentions:
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Psychosocial characteristics of candidates for implantable pain devices: validation of an assessment model. Pain Manag. 2020 Nov 13.
Gould HM, D'Eon MS, Grinberg AM, Chakravarthy KV, Castellanos J, Rutledge T. PMID: 33183132.
View in: PubMed Mentions: Fields:
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Strategic testing plan for Ambulatory Surgery Centers (ASCs) after the COVID-19 pandemic. Disaster Med Public Health Prep. 2020 Nov 04; 1-20.
Naidu R, Sheth S, Chaturvedi R, Chakravarthy K. PMID: 33143808.
View in: PubMed Mentions: Fields:
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Single arm prospective multicenter case series on the use of burst stimulation to improve pain and motor symptoms in Parkinson's disease. Bioelectron Med. 2020; 6:18.
Chakravarthy KV, Chaturvedi R, Agari T, Iwamuro H, Reddy R, Matsui A. PMID: 33005705.
View in: PubMed Mentions:
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Cybersecurity Risks in a Pandemic. J Med Internet Res. 2020 09 17; 22(9):e23692.
Williams CM, Chaturvedi R, Chakravarthy K. PMID: 32897869.
View in: PubMed Mentions: Fields: Translation: HumansPHPublic Health
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A Comprehensive Practice Guideline for Magnetic Resonance Imaging Compatibility in Implanted Neuromodulation Devices. Neuromodulation. 2020 Oct; 23(7):893-911.
Sayed D, Chakravarthy K, Amirdelfan K, Kalia H, Meacham K, Shirvalkar P, Falowski S, Petersen E, Hagedorn JM, Pope J, Leever J, Deer T. PMID: 32809275.
View in: PubMed Mentions: 1 Fields:
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Emergence From the COVID-19 Pandemic and the Care of Chronic Pain: Guidance for the Interventionalist. Anesth Analg. 2020 08; 131(2):387-394.
Deer TR, Sayed D, Pope JE, Chakravarthy KV, Petersen E, Moeschler SM, Abd-Elsayed A, Amirdelfan K, Mekhail N. PMID: 32452905.
View in: PubMed Mentions: 2 Fields: Translation: HumansCellsPHPublic Health
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Composite Score Is a Better Reflection of Patient Response to Chronic Pain Therapy Compared With Pain Intensity Alone. Neuromodulation. 2020 Jun 27.
Pilitsis JG, Fahey M, Custozzo A, Chakravarthy K, Capobianco R. PMID: 32592618.
View in: PubMed Mentions: 2 Fields:
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Efficacy of Serology Testing in Predicting Reinfection in Patients With SARS-CoV-2. Disaster Med Public Health Prep. 2020 Jun 24; 1-3.
Chaturvedi R, Naidu R, Sheth S, Chakravarthy K. PMID: 32576315.
View in: PubMed Mentions: 3 Fields:
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Novel Intermittent Dosing Burst Paradigm in Spinal Cord Stimulation. Neuromodulation. 2020 Mar 23.
Deer TR, Patterson DG, Baksh J, Pope JE, Mehta P, Raza A, Agnesi F, Chakravarthy KV. PMID: 32202044.
View in: PubMed Mentions: Fields:
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Spinal cord stimulation in Parkinson's disease: a review of the preclinical and clinical data and future prospects. Bioelectron Med. 2020; 6:5.
Cai Y, Reddy RD, Varshney V, Chakravarthy KV. PMID: 32232113.
View in: PubMed Mentions:
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Research Reports in Clinical Cardiology. A Review of Neuromodulation in the Treatment of Cardiovascular Disease. 2020; 11:7-18.
Yang A, Chakravarthy KV, Pope JE, Deer TR.
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A Review of Clinical Data on Salvage Therapy in Spinal Cord Stimulation. Neuromodulation. 2020 Jul; 23(5):562-571.
Reddy RD, Moheimani R, Yu GG, Chakravarthy KV. PMID: 31697457.
View in: PubMed Mentions: Fields:
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Prospective case series on the use of peripheral nerve stimulation for focal mononeuropathy treatment. Pain Manag. 2019 Nov; 9(6):551-558.
Oswald J, Shahi V, Chakravarthy KV. PMID: 31686589.
View in: PubMed Mentions: 1 Fields: Translation: Humans
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Leptin and Associated Mediators of Immunometabolic Signaling: Novel Molecular Outcome Measures for Neurostimulation to Treat Chronic Pain. Int J Mol Sci. 2019 Sep 24; 20(19).
Kinfe TM, Buchfelder M, Chaudhry SR, Chakravarthy KV, Deer TR, Russo M, Georgius P, Hurlemann R, Rasheed M, Muhammad S, Yearwood TL. PMID: 31554241.
View in: PubMed Mentions: Fields: Translation: HumansAnimalsCells
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Updated Review and Treatment Recommendations on Paraneoplastic Neurologic Syndromes and Chronic Pain. Pain Physician. 2019 09; 22(5):433-445.
Blyakhman I, Chakravarthy K. PMID: 31561645.
View in: PubMed Mentions: Fields: Translation: Humans
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Unilateral L4-dorsal root ganglion stimulation evokes pain relief in chronic neuropathic postsurgical knee pain and changes of inflammatory markers: part II whole transcriptome profiling. J Transl Med. 2019 06 19; 17(1):205.
Kinfe TM, Asif M, Chakravarthy KV, Deer TR, Kramer JM, Yearwood TL, Hurlemann R, Hussain MS, Motameny S, Wagle P, Nürnberg P, Gravius S, Randau T, Gravius N, Chaudhry SR, Muhammad S. PMID: 31217010.
View in: PubMed Mentions: 1 Fields: Translation: HumansCTClinical Trials
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Mechanism of Action in Burst Spinal Cord Stimulation: Review and Recent Advances. Pain Med. 2019 06 01; 20(Suppl 1):S13-S22.
Chakravarthy K, Fishman MA, Zuidema X, Hunter CW, Levy R. PMID: 31152180.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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A Comprehensive Algorithm for Management of Neuropathic Pain. Pain Med. 2019 06 01; 20(Suppl 1):S2-S12.
Bates D, Schultheis BC, Hanes MC, Jolly SM, Chakravarthy KV, Deer TR, Levy RM, Hunter CW. PMID: 31152178.
View in: PubMed Mentions: 6 Fields: Translation: Humans
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Burst Spinal Cord Stimulation: A Systematic Review and Pooled Analysis of Real-World Evidence and Outcomes Data. Pain Med. 2019 06 01; 20(Suppl 1):S47-S57.
Chakravarthy K, Malayil R, Kirketeig T, Deer T. PMID: 31152177.
View in: PubMed Mentions: 3 Fields: Translation: Humans
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Human Brain/Cloud Interface. Front Neurosci. 2019; 13:112.
Martins NRB, Angelica A, Chakravarthy K, Svidinenko Y, Boehm FJ, Opris I, Lebedev MA, Swan M, Garan SA, Rosenfeld JV, Hogg T, Freitas RA. PMID: 30983948.
View in: PubMed Mentions:
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Saliva molecular inflammatory profiling in female migraine patients responsive to adjunctive cervical non-invasive vagus nerve stimulation: the MOXY Study. J Transl Med. 2019 02 22; 17(1):53.
Boström A, Scheele D, Stoffel-Wagner B, Hönig F, Chaudhry SR, Muhammad S, Hurlemann R, Krauss JK, Lendvai IS, Chakravarthy KV, Kinfe TM. PMID: 30795781.
View in: PubMed Mentions: Fields: Translation: HumansCTClinical Trials
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Fluorescence lateral flow immunoassay-based point-of-care nanodiagnostics for orthopedic implant-associated infection. 2019; 280:24-33.
Vivek Borse, Scott Nodzo, Donald Hohman, Krishnan Chakravarthy, Rohit Srivastava.
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A revised psychosocial assessment model for implantable pain devices to improve their evidence basis and consensus with updated pain management guidelines. Pain Manag. 2019 Mar 01; 9(2):139-149.
Grinberg AM, D'Eon MS, Ellison JK, Rutledge T, Castellanos J, Chakravarthy KV. PMID: 30681019.
View in: PubMed Mentions: Fields: Translation: Humans
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Neurostimulation for Intractable Chronic Pain. Brain Sci. 2019 Jan 24; 9(2).
Deer TR, Jain S, Hunter C, Chakravarthy K. PMID: 30682776.
View in: PubMed Mentions:
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Progress in noninvasive, abortive neuromodulation therapy for treating acute pain in primary headache disorders. Pain Manag. 2019 01 01; 9(1):9-11.
Chakravarthy KV, Kinfe TM, Christo PJ. PMID: 30507293.
View in: PubMed Mentions: Fields: Translation: Humans
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Reframing the Role of Neuromodulation Therapy in the Chronic Pain Treatment Paradigm. Pain Physician. 2018 11; 21(6):507-513.
Chakravarthy K, Manchikanti L, Kaye AD, Christo PJ. PMID: 30508982.
View in: PubMed Mentions: 6 Fields:
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Selective L4 Dorsal Root Ganglion Stimulation Evokes Pain Relief and Changes of Inflammatory Markers: Part I Profiling of Saliva and Serum Molecular Patterns. Neuromodulation. 2019 Jan; 22(1):44-52.
Gravius N, Chaudhry SR, Muhammad S, Boström A, Gravius S, Randau T, Scheele D, Westhofen P, Kruppenbacher J, Stoffel-Wagner B, Maier C, Weidlich A, Yearwood TL, Chakravarthy KV, Kramer JM, Hurlemann R, Kinfe TM. PMID: 30358008.
View in: PubMed Mentions: 4 Fields: Translation: HumansCTClinical Trials
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Noninvasive Transdermal Delivery System of Lidocaine Using an Acoustic Droplet-Vaporization Based Wearable Patch. Small. 2018 12; 14(49):e1803266.
Soto F, Jeerapan I, Silva-López C, Lopez-Ramirez MA, Chai I, Xiaolong L, Lv J, Kurniawan JF, Martin I, Chakravarthy K, Wang J. PMID: 30369022.
View in: PubMed Mentions: 4 Fields: Translation: HumansAnimalsCells
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A Review of Spinal and Peripheral Neuromodulation and Neuroinflammation: Lessons Learned Thus Far and Future Prospects of Biotype Development. Neuromodulation. 2019 Apr; 22(3):235-243.
Chakravarthy KV, Xing F, Bruno K, Kent AR, Raza A, Hurlemann R, Kinfe TM. PMID: 30311715.
View in: PubMed Mentions: 4 Fields: Translation: Humans
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Targeting toll-like receptor-4 (TLR4)-an emerging therapeutic target for persistent pain states. Pain. 2018 Oct; 159(10):1908-1915.
Bruno K, Woller SA, Miller YI, Yaksh TL, Wallace M, Beaton G, Chakravarthy K. PMID: 29889119.
View in: PubMed Mentions: 11 Fields: Translation: HumansAnimals
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The Neuromodulation Appropriateness Consensus Committee on Best Practices for Dorsal Root Ganglion Stimulation. Neuromodulation. 2019 Jan; 22(1):1-35.
Deer TR, Pope JE, Lamer TJ, Grider JS, Provenzano D, Lubenow TR, FitzGerald JJ, Hunter C, Falowski S, Sayed D, Baranidharan G, Patel NK, Davis T, Green A, Pajuelo A, Epstein LJ, Harned M, Liem L, Christo PJ, Chakravarthy K, Gilmore C, Huygen F, Lee E, Metha P, Nijhuis H, Patterson DG, Petersen E, Pilitsis JG, Rowe JJ, Rupert MP, Skaribas I, Sweet J, Verrills P, Wilson D, Levy RM, Mekhail N. PMID: 30246899.
View in: PubMed Mentions: 6 Fields: Translation: Humans
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Burst Spinal Cord Stimulation: Review of Preclinical Studies and Comments on Clinical Outcomes. Neuromodulation. 2018 Jul; 21(5):431-439.
Chakravarthy K, Kent AR, Raza A, Xing F, Kinfe TM. PMID: 29431275.
View in: PubMed Mentions: 5 Fields: Translation: HumansAnimals
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Nanotechnology: A Promising New Paradigm for the Control of Pain. Pain Med. 2018 02 01; 19(2):232-243.
Chakravarthy KV, Boehm FJ, Christo PJ. PMID: 29036629.
View in: PubMed Mentions: 3 Fields: Translation: HumansAnimals
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Anesthetic Management of Pheochromocytoma Resection in Adults with Single Ventricle Physiology. Cureus. 2017 Dec 08; 9(12):e1928.
Suffredini G, Diaz-Rodriguez N, Chakravarthy K, Mathur A, Hayanga HK, Frank SM, Ringel RE, Freiberg S, Barodka VM, Steppan J. PMID: 29464136.
View in: PubMed Mentions:
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Spinal Cord Stimulation for Treating Chronic Pain: Reviewing Preclinical and Clinical Data on Paresthesia-Free High-Frequency Therapy. Neuromodulation. 2018 Jan; 21(1):10-18.
Chakravarthy K, Richter H, Christo PJ, Williams K, Guan Y. PMID: 29105244.
View in: PubMed Mentions: 14 Fields: Translation: HumansAnimals
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Stem Cell Therapy for Chronic Pain Management: Review of Uses, Advances, and Adverse Effects. Pain Physician. 2017 05; 20(4):293-305.
Chakravarthy K, Chen Y, He C, Christo PJ. PMID: 28535552.
View in: PubMed Mentions: 4 Fields: Translation: Humans
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Review of Recent Advances in Peripheral Nerve Stimulation (PNS). Curr Pain Headache Rep. 2016 Nov; 20(11):60.
Chakravarthy K, Nava A, Christo PJ, Williams K. PMID: 27671799.
View in: PubMed Mentions: 15 Fields: Translation: Humans
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Superseding the Hourglass Effect Toward the Successful Commercialization of Nanotechnology in the Medical Sciences - We Require a Change in Perspective. Cureus. 2016 Jul 05; 8(7):e670.
Chakravarthy K, Boehm F, Sanhai-Madar W. PMID: 27551650.
View in: PubMed Mentions:
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Review of the Uses of Vagal Nerve Stimulation in Chronic Pain Management. Curr Pain Headache Rep. 2015 Dec; 19(12):54.
Chakravarthy K, Chaudhry H, Williams K, Christo PJ. PMID: 26493698.
View in: PubMed Mentions: 20 Fields: Translation: HumansAnimals
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Halothane modulates the type i interferon response to influenza and minimizes the risk of secondary bacterial pneumonia through maintenance of neutrophil recruitment in an animal model. Anesthesiology. 2015 Sep; 123(3):590-602.
MacDonald BA, Chakravarthy KV, Davidson BA, Mullan BA, Alluri R, Hakansson AP, Knight PR. PMID: 26120770.
View in: PubMed Mentions: 4 Fields: Translation: AnimalsCells
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Nanotechnology: why should we care? Am J Orthop (Belle Mead NJ). 2015 Mar; 44(3):E87-8.
Nodzo SR, Hohman DW, Chakravarthy K. PMID: 25750958.
View in: PubMed Mentions: 3 Fields: Translation: Humans
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Epidural steroid injections: an updated review on recent trends in safety and complications. Pain Manag. 2015; 5(2):129-46.
Bicket MC, Chakravarthy K, Chang D, Cohen SP. PMID: 25806907.
View in: PubMed Mentions: 12 Fields: Translation: Humans
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Neuroradiology, Anesthesia, Bioengineering, and Hardware Programming in the Clinical Applications of Deep Brain Stimulation. 2014; 6(4):172.
Ayden Jacob, Krishnan Chakravarthy . . View Publication.
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Engineering Magnetic Nanoparticles for Thermo-Ablation and Drug Delivery in Neurological Cancers. 2014; 6(4):170.
Ayden Jacob, Krishnan Chakravarthy. . View Publication.
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Doxorubicin-conjugated quantum dots to target alveolar macrophages and inflammation. Nanomedicine. 2011 Feb; 7(1):88-96.
Chakravarthy KV, Davidson BA, Helinski JD, Ding H, Law WC, Yong KT, Prasad PN, Knight PR. PMID: 20887813.
View in: PubMed Mentions: 20 Fields: Translation: AnimalsCells
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Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication. Proc Natl Acad Sci U S A. 2010 Jun 01; 107(22):10172-7.
Chakravarthy KV, Bonoiu AC, Davis WG, Ranjan P, Ding H, Hu R, Bowzard JB, Bergey EJ, Katz JM, Knight PR, Sambhara S, Prasad PN. PMID: 20498074.
View in: PubMed Mentions: 30 Fields: Translation: HumansCells
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Year | Publications |
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2010 | 2 | 2014 | 2 | 2015 | 4 | 2016 | 2 | 2017 | 3 | 2018 | 9 | 2019 | 13 | 2020 | 13 |
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