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Krishna Sriram

Title(s)Postdoctoral Scholar, Pharmacology
SchoolHealth Sciences
Emailksriram@ucsd.edu
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sriram K, Moyung K, Corriden R, Carter H, Insel PA. GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors. PLoS Biol. 2019 Nov; 17(11):e3000434. PMID: 31765370.
      View in: PubMed
    2. Sriram K, Wiley SZ, Moyung K, Gorr MW, Salmerón C, Marucut J, French RP, Lowy AM, Insel PA. Detection and Quantification of GPCR mRNA: An Assessment and Implications of Data from High-Content Methods. ACS Omega. 2019 Oct 15; 4(16):17048-17059. PMID: 31646252.
      View in: PubMed
    3. Insel PA, Sriram K, Gorr MW, Wiley SZ, Michkov A, Salmerón C, Chinn AM. GPCRomics: An Approach to Discover GPCR Drug Targets. Trends Pharmacol Sci. 2019 Jun; 40(6):378-387. PMID: 31078319.
      View in: PubMed
    4. Wiley SZ, Sriram K, Salmerón C, Insel PA. GPR68: An Emerging Drug Target in Cancer. Int J Mol Sci. 2019 Jan 28; 20(3). PMID: 30696114.
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    5. Insel PA, Sriram K, Wiley SZ, Wilderman A, Katakia T, McCann T, Yokouchi H, Zhang L, Corriden R, Liu D, Feigin ME, French RP, Lowy AM, Murray F. GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic Targets. Front Pharmacol. 2018; 9:431. PMID: 29872392.
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    6. Wiley SZ, Sriram K, Liang W, Chang SE, French R, McCann T, Sicklick J, Nishihara H, Lowy AM, Insel PA. GPR68, a proton-sensing GPCR, mediates interaction of cancer-associated fibroblasts and cancer cells. FASEB J. 2018 03; 32(3):1170-1183. PMID: 29092903.
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    7. Sriram K, Insel PA. G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs? Mol Pharmacol. 2018 04; 93(4):251-258. PMID: 29298813.
      View in: PubMed
    8. Sriram K, Laughlin JG, Rangamani P, Tartakovsky DM. Shear-Induced Nitric Oxide Production by Endothelial Cells. Biophys J. 2016 Jul 12; 111(1):208-21. PMID: 27410748.
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    9. Jung G, Fajardo G, Ribeiro AJ, Kooiker KB, Coronado M, Zhao M, Hu DQ, Reddy S, Kodo K, Sriram K, Insel PA, Wu JC, Pruitt BL, Bernstein D. Time-dependent evolution of functional vs. remodeling signaling in induced pluripotent stem cell-derived cardiomyocytes and induced maturation with biomechanical stimulation. FASEB J. 2016 Apr; 30(4):1464-79. PMID: 26675706.
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    10. Insel PA, Wilderman A, Zambon AC, Snead AN, Murray F, Aroonsakool N, McDonald DS, Zhou S, McCann T, Zhang L, Sriram K, Chinn AM, Michkov AV, Lynch RM, Overland AC, Corriden R. G Protein-Coupled Receptor (GPCR) Expression in Native Cells: "Novel" endoGPCRs as Physiologic Regulators and Therapeutic Targets. Mol Pharmacol. 2015 Jul; 88(1):181-7. PMID: 25737495.
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    11. Sriram K, Intaglietta M, Tartakovsky DM. Non-Newtonian flow of blood in arterioles: consequences for wall shear stress measurements. Microcirculation. 2014 Oct; 21(7):628-39. PMID: 24703006.
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    12. Sriram K, Intaglietta M, Tartakovsky DM. Hematocrit dispersion in asymmetrically bifurcating vascular networks. Am J Physiol Heart Circ Physiol. 2014 Dec 01; 307(11):H1576-86. PMID: 25217657.
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    13. Sriram K, Salazar Vázquez BY, Tsai AG, Cabrales P, Intaglietta M, Tartakovsky DM. Autoregulation and mechanotransduction control the arteriolar response to small changes in hematocrit. Am J Physiol Heart Circ Physiol. 2012 Nov 01; 303(9):H1096-106. PMID: 22923620.
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    14. Sriram K, Tsai AG, Cabrales P, Meng F, Acharya SA, Tartakovsky DM, Intaglietta M. PEG-albumin supraplasma expansion is due to increased vessel wall shear stress induced by blood viscosity shear thinning. Am J Physiol Heart Circ Physiol. 2012 Jun 15; 302(12):H2489-97. PMID: 22505638.
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    15. Hightower CM, Salazar Vázquez BY, Woo Park S, Sriram K, Martini J, Yalcin O, Tsai AG, Cabrales P, Tartakovsky DM, Johnson PC, Intaglietta M. Integration of cardiovascular regulation by the blood/endothelium cell-free layer. Wiley Interdiscip Rev Syst Biol Med. 2011 Jul-Aug; 3(4):458-70. PMID: 21523919.
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    16. Sriram K, Vázquez BY, Yalcin O, Johnson PC, Intaglietta M, Tartakovsky DM. The effect of small changes in hematocrit on nitric oxide transport in arterioles. Antioxid Redox Signal. 2011 Jan 15; 14(2):175-85. PMID: 20560785.
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    17. Sriram K, Lin GX, Jefferson AM, Roberts JR, Wirth O, Hayashi Y, Krajnak KM, Soukup JM, Ghio AJ, Reynolds SH, Castranova V, Munson AE, Antonini JM. Mitochondrial dysfunction and loss of Parkinson's disease-linked proteins contribute to neurotoxicity of manganese-containing welding fumes. FASEB J. 2010 Dec; 24(12):4989-5002. PMID: 20798247.
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    18. Sriram K, Matheson JM, Benkovic SA, Miller DB, Luster MI, O'Callaghan JP. Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha. FASEB J. 2006 Apr; 20(6):670-82. PMID: 16581975.
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    19. Sriram K, Benkovic SA, Hebert MA, Miller DB, O'Callaghan JP. Induction of gp130-related cytokines and activation of JAK2/STAT3 pathway in astrocytes precedes up-regulation of glial fibrillary acidic protein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of neurodegeneration: key signaling pathway for astrogliosis in vivo? J Biol Chem. 2004 May 07; 279(19):19936-47. PMID: 14996842.
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    20. Sriram K, Matheson JM, Benkovic SA, Miller DB, Luster MI, O'Callaghan JP. Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease. FASEB J. 2002 Sep; 16(11):1474-6. PMID: 12205053.
      View in: PubMed