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Krishna Sriram

Title(s)Postdoctoral Scholar, Pharmacology
SchoolHealth Sciences
Address9500 Gilman Drive #0636
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Proteinase-activated receptor 1 (PAR1): A target for repurposing in the treatment of COVID-19? Br J Pharmacol. 2020 Jul 08. Sriram K, Insel PA. PMID: 32639031.
      View in: PubMed   Mentions:    Fields:    
    2. Transcriptomic analysis of pulmonary artery smooth muscle cells identifies new potential therapeutic targets for idiopathic pulmonary arterial hypertension. Br J Pharmacol. 2020 Aug; 177(15):3505-3518. Gorr MW, Sriram K, Muthusamy A, Insel PA. PMID: 32337710.
      View in: PubMed   Mentions: 1     Fields:    
    3. A hypothesis for pathobiology and treatment of COVID-19: The centrality of ACE1/ACE2 imbalance. Br J Pharmacol. 2020 Apr 24. Sriram K, Insel PA. PMID: 32333398.
      View in: PubMed   Mentions: 1     Fields:    
    4. Risks of ACE Inhibitor and ARB Usage in COVID-19: Evaluating the Evidence. Clin Pharmacol Ther. 2020 Apr 22. Sriram K, Insel PA. PMID: 32320478.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsPHPublic Health
    5. GPCRs in pancreatic adenocarcinoma: Contributors to tumour biology and novel therapeutic targets. Br J Pharmacol. 2020 Jun; 177(11):2434-2455. Sriram K, Salmerón C, Wiley SZ, Insel PA. PMID: 32060895.
      View in: PubMed   Mentions:    Fields:    
    6. Proton-sensing G protein-coupled receptors: detectors of tumor acidosis and candidate drug targets. Future Med Chem. 2020 Mar; 12(6):523-532. Insel PA, Sriram K, Salmerón C, Wiley SZ. PMID: 32116003.
      View in: PubMed   Mentions:    Fields:    
    7. GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors. PLoS Biol. 2019 11; 17(11):e3000434. Sriram K, Moyung K, Corriden R, Carter H, Insel PA. PMID: 31765370.
      View in: PubMed   Mentions:    Fields:    
    8. Detection and Quantification of GPCR mRNA: An Assessment and Implications of Data from High-Content Methods. ACS Omega. 2019 Oct 15; 4(16):17048-17059. Sriram K, Wiley SZ, Moyung K, Gorr MW, Salmerón C, Marucut J, French RP, Lowy AM, Insel PA. PMID: 31646252.
      View in: PubMed   Mentions:
    9. GPCRomics: An Approach to Discover GPCR Drug Targets. Trends Pharmacol Sci. 2019 06; 40(6):378-387. Insel PA, Sriram K, Gorr MW, Wiley SZ, Michkov A, Salmerón C, Chinn AM. PMID: 31078319.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    10. GPR68: An Emerging Drug Target in Cancer. Int J Mol Sci. 2019 Jan 28; 20(3). Wiley SZ, Sriram K, Salmerón C, Insel PA. PMID: 30696114.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    11. GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic Targets. Front Pharmacol. 2018; 9:431. Insel PA, Sriram K, Wiley SZ, Wilderman A, Katakia T, McCann T, Yokouchi H, Zhang L, Corriden R, Liu D, Feigin ME, French RP, Lowy AM, Murray F. PMID: 29872392.
      View in: PubMed   Mentions:
    12. GPR68, a proton-sensing GPCR, mediates interaction of cancer-associated fibroblasts and cancer cells. FASEB J. 2018 03; 32(3):1170-1183. Wiley SZ, Sriram K, Liang W, Chang SE, French R, McCann T, Sicklick J, Nishihara H, Lowy AM, Insel PA. PMID: 29092903.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    13. G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs? Mol Pharmacol. 2018 04; 93(4):251-258. Sriram K, Insel PA. PMID: 29298813.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    14. Shear-Induced Nitric Oxide Production by Endothelial Cells. Biophys J. 2016 Jul 12; 111(1):208-21. Sriram K, Laughlin JG, Rangamani P, Tartakovsky DM. PMID: 27410748.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    15. Time-dependent evolution of functional vs. remodeling signaling in induced pluripotent stem cell-derived cardiomyocytes and induced maturation with biomechanical stimulation. FASEB J. 2016 Apr; 30(4):1464-79. Jung G, Fajardo G, Ribeiro AJ, Kooiker KB, Coronado M, Zhao M, Hu DQ, Reddy S, Kodo K, Sriram K, Insel PA, Wu JC, Pruitt BL, Bernstein D. PMID: 26675706.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    16. G Protein-Coupled Receptor (GPCR) Expression in Native Cells: "Novel" endoGPCRs as Physiologic Regulators and Therapeutic Targets. Mol Pharmacol. 2015 Jul; 88(1):181-7. Insel PA, Wilderman A, Zambon AC, Snead AN, Murray F, Aroonsakool N, McDonald DS, Zhou S, McCann T, Zhang L, Sriram K, Chinn AM, Michkov AV, Lynch RM, Overland AC, Corriden R. PMID: 25737495.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    17. Non-Newtonian flow of blood in arterioles: consequences for wall shear stress measurements. Microcirculation. 2014 Oct; 21(7):628-39. Sriram K, Intaglietta M, Tartakovsky DM. PMID: 24703006.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    18. Hematocrit dispersion in asymmetrically bifurcating vascular networks. Am J Physiol Heart Circ Physiol. 2014 Dec 01; 307(11):H1576-86. Sriram K, Intaglietta M, Tartakovsky DM. PMID: 25217657.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    19. Autoregulation and mechanotransduction control the arteriolar response to small changes in hematocrit. Am J Physiol Heart Circ Physiol. 2012 Nov 01; 303(9):H1096-106. Sriram K, Salazar Vázquez BY, Tsai AG, Cabrales P, Intaglietta M, Tartakovsky DM. PMID: 22923620.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    20. PEG-albumin supraplasma expansion is due to increased vessel wall shear stress induced by blood viscosity shear thinning. Am J Physiol Heart Circ Physiol. 2012 Jun 15; 302(12):H2489-97. Sriram K, Tsai AG, Cabrales P, Meng F, Acharya SA, Tartakovsky DM, Intaglietta M. PMID: 22505638.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    21. Array-comparative genomic hybridization reveals loss of SOCS6 is associated with poor prognosis in primary lung squamous cell carcinoma. PLoS One. 2012; 7(2):e30398. Sriram KB, Larsen JE, Savarimuthu Francis SM, Wright CM, Clarke BE, Duhig EE, Brown KM, Hayward NK, Yang IA, Bowman RV, Fong KM. PMID: 22363434.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    22. Diagnostic molecular biomarkers for malignant pleural effusions. Future Oncol. 2011 Jun; 7(6):737-52. Sriram KB, Relan V, Clarke BE, Duhig EE, Yang IA, Bowman RV, Lee YC, Fong KM. PMID: 21675837.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    23. Integration of cardiovascular regulation by the blood/endothelium cell-free layer. Wiley Interdiscip Rev Syst Biol Med. 2011 Jul-Aug; 3(4):458-70. Hightower CM, Salazar Vázquez BY, Woo Park S, Sriram K, Martini J, Yalcin O, Tsai AG, Cabrales P, Tartakovsky DM, Johnson PC, Intaglietta M. PMID: 21523919.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    24. The effect of small changes in hematocrit on nitric oxide transport in arterioles. Antioxid Redox Signal. 2011 Jan 15; 14(2):175-85. Sriram K, Vázquez BY, Yalcin O, Johnson PC, Intaglietta M, Tartakovsky DM. PMID: 20560785.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    25. Mitochondrial dysfunction and loss of Parkinson's disease-linked proteins contribute to neurotoxicity of manganese-containing welding fumes. FASEB J. 2010 Dec; 24(12):4989-5002. Sriram K, Lin GX, Jefferson AM, Roberts JR, Wirth O, Hayashi Y, Krajnak KM, Soukup JM, Ghio AJ, Reynolds SH, Castranova V, Munson AE, Antonini JM. PMID: 20798247.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsPHPublic Health
    26. Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha. FASEB J. 2006 Apr; 20(6):670-82. Sriram K, Matheson JM, Benkovic SA, Miller DB, Luster MI, O'Callaghan JP. PMID: 16581975.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    27. Induction of gp130-related cytokines and activation of JAK2/STAT3 pathway in astrocytes precedes up-regulation of glial fibrillary acidic protein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of neurodegeneration: key signaling pathway for astrogliosis in vivo? J Biol Chem. 2004 May 07; 279(19):19936-47. Sriram K, Benkovic SA, Hebert MA, Miller DB, O'Callaghan JP. PMID: 14996842.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    28. Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease. FASEB J. 2002 Sep; 16(11):1474-6. Sriram K, Matheson JM, Benkovic SA, Miller DB, Luster MI, O'Callaghan JP. PMID: 12205053.
      View in: PubMed   Mentions: 99     Fields:    Translation:Animals
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