Kathryn Morelli

Title(s)Postdoctoral Scholar, Cellular and Molecular Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Development of RNA-Directed Therapeutics for Myotonic Dystrophy Type 1 Neuropathology
    NIH F32NS112654Jul 1, 2019 - Dec 31, 2021
    Role: Principal Investigator
    A Personalized Gene Therapy Approach for Charcot-Marie-Tooth Disease
    NIH F31NS098540Mar 2, 2017 - Mar 1, 2019
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. MECP2-related pathways are dysregulated in a cortical organoid model of myotonic dystrophy. Sci Transl Med. 2022 06 29; 14(651):eabn2375. Morelli KH, Jin W, Shathe S, Madrigal AA, Jones KL, Schwartz JL, Bridges T, Mueller JR, Shankar A, Chaim IA, Day JW, Yeo GW. PMID: 35767654.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Gene therapies for axonal neuropathies: Available strategies, successes to date, and what to target next. Brain Res. 2020 04 01; 1732:146683. Morelli KH, Hatton CL, Harper SQ, Burgess RW. PMID: 32001243; PMCID: PMC7060803.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    3. Allele-specific RNA interference prevents neuropathy in Charcot-Marie-Tooth disease type 2D mouse models. J Clin Invest. 2019 12 02; 129(12):5568-5583. Morelli KH, Griffin LB, Pyne NK, Wallace LM, Fowler AM, Oprescu SN, Takase R, Wei N, Meyer-Schuman R, Mellacheruvu D, Kitzman JO, Kocen SG, Hines TJ, Spaulding EL, Lupski JR, Nesvizhskii A, Mancias P, Butler IJ, Yang XL, Hou YM, Antonellis A, Harper SQ, Burgess RW. PMID: 31557132; PMCID: PMC6877339.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    4. HSP90 Inhibitor, NVP-AUY922, Improves Myelination in Vitro and Supports the Maintenance of Myelinated Axons in Neuropathic Mice. ACS Chem Neurosci. 2019 06 19; 10(6):2890-2902. Chittoor-Vinod VG, Bazick H, Todd AG, Falk D, Morelli KH, Burgess RW, Foster TC, Notterpek L. PMID: 31017387; PMCID: PMC6588339.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    5. Severity of Demyelinating and Axonal Neuropathy Mouse Models Is Modified by Genes Affecting Structure and Function of Peripheral Nodes. Cell Rep. 2017 03 28; 18(13):3178-3191. Morelli KH, Seburn KL, Schroeder DG, Spaulding EL, Dionne LA, Cox GA, Burgess RW. PMID: 28355569; PMCID: PMC5415377.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    6. Metabolite profile of a mouse model of Charcot-Marie-Tooth type 2D neuropathy: implications for disease mechanisms and interventions. Biol Open. 2016 Jul 15; 5(7):908-20. Bais P, Beebe K, Morelli KH, Currie ME, Norberg SN, Evsikov AV, Miers KE, Seburn KL, Guergueltcheva V, Kremensky I, Jordanova A, Bult CJ, Burgess RW. PMID: 27288508; PMCID: PMC4958279.
      View in: PubMed   Mentions: 3     Fields:    
    7. Synaptic Deficits at Neuromuscular Junctions in Two Mouse Models of Charcot-Marie-Tooth Type 2d. J Neurosci. 2016 Mar 16; 36(11):3254-67. Spaulding EL, Sleigh JN, Morelli KH, Pinter MJ, Burgess RW, Seburn KL. PMID: 26985035; PMCID: PMC4792937.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    8. Lack of neuropathy-related phenotypes in hint1 knockout mice. J Neuropathol Exp Neurol. 2014 Jul; 73(7):693-701. Seburn KL, Morelli KH, Jordanova A, Burgess RW. PMID: 24918641; PMCID: PMC4098130.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
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