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    Katerina Otrubova

    TitlePostdoctoral Scholar
    SchoolUniversity of California, San Diego
    DepartmentSchool of Pharmacy and Pharmaceutical Science
    Address9500 Gilman Drive #0719
    CA La Jolla 92093
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Otrubova K, Srinivasan V, Boger DL. Discovery libraries targeting the major enzyme classes: the serine hydrolases. Bioorg Med Chem Lett. 2014 Aug 15; 24(16):3807-13. PMID: 25037918; PMCID: PMC4130767.
      2. Duncan KK, Otrubova K, Boger DL. a-Ketoheterocycle inhibitors of fatty acid amide hydrolase: exploration of conformational constraints in the acyl side chain. Bioorg Med Chem. 2014 May 01; 22(9):2763-70. PMID: 24690529; PMCID: PMC4029506.
      3. Otrubova K, Cravatt BF, Boger DL. Design, synthesis, and characterization of a-ketoheterocycles that additionally target the cytosolic port Cys269 of fatty acid amide hydrolase. J Med Chem. 2014 Feb 13; 57(3):1079-89. PMID: 24456116; PMCID: PMC3940414.
      4. Barker TJ, Duncan KK, Otrubova K, Boger DL. Potent Vinblastine C20' Ureas Displaying Additionally Improved Activity Against a Vinblastine-Resistant Cancer Cell Line. ACS Med Chem Lett. 2013 Sep 09; 4(10). PMID: 24223237.
        View in: PubMed
      5. Otrubova K, Brown M, McCormick MS, Han GW, O'Neal ST, Cravatt BF, Stevens RC, Lichtman AH, Boger DL. Rational design of fatty acid amide hydrolase inhibitors that act by covalently bonding to two active site residues. J Am Chem Soc. 2013 Apr 24; 135(16):6289-99. PMID: 23581831; PMCID: PMC3678763.
      6. Otrubova K, Boger DL. a-Ketoheterocycle-based Inhibitors of Fatty Acid Amide Hydrolase (FAAH). ACS Chem Neurosci. 2012 May 16; 3(5):340-348. PMID: 22639704.
        View in: PubMed
      7. Otrubova K, Ezzili C, Boger DL. The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH). Bioorg Med Chem Lett. 2011 Aug 15; 21(16):4674-85. PMID: 21764305; PMCID: PMC3146581.
      8. Ezzili C, Otrubova K, Boger DL. Fatty acid amide signaling molecules. Bioorg Med Chem Lett. 2010 Oct 15; 20(20):5959-68. PMID: 20817522; PMCID: PMC2942981.
      9. Otrubova K, Lushington G, Vander Velde D, McGuire KL, McAlpine SR. Comprehensive study of sansalvamide A derivatives and their structure-activity relationships against drug-resistant colon cancer cell lines. J Med Chem. 2008 Feb 14; 51(3):530-44. PMID: 18186604.
        View in: PubMed
      10. Otrubova K, McGuire KL, McAlpine SR. Scaffold targeting drug-resistant colon cancers. J Med Chem. 2007 May 03; 50(9):1999-2002. PMID: 17411027.
        View in: PubMed
      11. Rodriguez RA, Pan PS, Pan CM, Ravula S, Lapera S, Singh EK, Styers TJ, Brown JD, Cajica J, Parry E, Otrubova K, McAlpine SR. Synthesis of second-generation sansalvamide A derivatives: novel templates as potential antitumor agents. J Org Chem. 2007 Mar 16; 72(6):1980-2002. PMID: 17315929.
        View in: PubMed
      12. Styers TJ, Kekec A, Rodriguez R, Brown JD, Cajica J, Pan PS, Parry E, Carroll CL, Medina I, Corral R, Lapera S, Otrubova K, Pan CM, McGuire KL, McAlpine SR. Synthesis of Sansalvamide A derivatives and their cytotoxicity in the MSS colon cancer cell line HT-29. Bioorg Med Chem. 2006 Aug 15; 14(16):5625-31. PMID: 16697205.
        View in: PubMed
      13. Otrubova K, Styers TJ, Pan PS, Rodriguez R, McGuire KL, McAlpine SR. Synthesis and novel structure-activity relationships of potent sansalvamide A derivatives. Chem Commun (Camb). 2006 Mar 07; (9):1033-4. PMID: 16491200.
        View in: PubMed
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