Katarzyna Kempinska

TitlePostdoctoral Scholar
InstitutionUniversity of California San Diego
Address200 W. Arbor Drive #8447
San Diego CA 92103
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    1. Anderson AM, Nguyen ML, Potter M, Rosario D, Kempinska K, Ellis RJ, Diccianni M, Letendre SL. Comparison of bead array and glass nanoreactor multi-analyte platforms for the evaluation of CNS and peripheral inflammatory markers during HIV infection. J Immunol Methods. 2018 Nov 20. PMID: 30468733.
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    2. Borkin D, Klossowski S, Pollock J, Miao H, Linhares B, Kempinska K, Jin Z, Purohit T, Wen B, He M, Sun D, Cierpicki T, Grembecka J. The complexity of blocking bivalent protein-protein interactions: development of a highly potent inhibitor of the menin-Mixed Lineage Leukemia (MLL) interaction. J Med Chem. 2018 May 08. PMID: 29738674.
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    3. Kempinska K, Malik B, Borkin D, Klossowski S, Shukla S, Miao H, Wang J, Cierpicki T, Grembecka J. Pharmacologic Inhibition of the Menin-MLL Interaction Leads to Transcriptional Repression of PEG10 and Blocks Hepatocellular Carcinoma. Mol Cancer Ther. 2018 Jan; 17(1):26-38. PMID: 29142068.
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    4. Kicielinska J, Szczygiel A, Rossowska J, Anger N, Kempinska K, Switalska M, Kaszowska M, Wietrzyk J, Boratynski J, Pajtasz-Piasecka E. Oral Administration of Polymyxin B Modulates the Activity of Lipooligosaccharide E. coli B against Lung Metastases in Murine Tumor Models. PLoS One. 2016; 11(2):e0148156. PMID: 26829479; PMCID: PMC4735115.
    5. Borkin D, Pollock J, Kempinska K, Purohit T, Li X, Wen B, Zhao T, Miao H, Shukla S, He M, Sun D, Cierpicki T, Grembecka J. Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL). J Med Chem. 2016 Feb 11; 59(3):892-913. PMID: 26744767.
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    6. He S, Malik B, Borkin D, Miao H, Shukla S, Kempinska K, Purohit T, Wang J, Chen L, Parkin B, Malek SN, Danet-Desnoyers G, Muntean AG, Cierpicki T, Grembecka J. Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner. Leukemia. 2016 Feb; 30(2):508-13. PMID: 26084867; PMCID: PMC4830728.
    7. Borkin D, He S, Miao H, Kempinska K, Pollock J, Chase J, Purohit T, Malik B, Zhao T, Wang J, Wen B, Zong H, Jones M, Danet-Desnoyers G, Guzman ML, Talpaz M, Bixby DL, Sun D, Hess JL, Muntean AG, Maillard I, Cierpicki T, Grembecka J. Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo. Cancer Cell. 2015 Apr 13; 27(4):589-602. PMID: 25817203; PMCID: PMC4415852.
    8. Goszczynski TM, Filip-Psurska B, Kempinska K, Wietrzyk J, Boratynski J. Hydroxyethyl starch as an effective methotrexate carrier in anticancer therapy. Pharmacol Res Perspect. 2014 Jun; 2(3):e00047. PMID: 25505592; PMCID: PMC4186415.
    9. Gubernator J, Lipka D, Korycinska M, Kempinska K, Milczarek M, Wietrzyk J, Hrynyk R, Barnert S, Süss R, Kozubek A. Efficient human breast cancer xenograft regression after a single treatment with a novel liposomal formulation of epirubicin prepared using the EDTA ion gradient method. PLoS One. 2014; 9(3):e91487. PMID: 24621591; PMCID: PMC3951386.
    10. Boryczka S, Bebenek E, Wietrzyk J, Kempinska K, Jastrzebska M, Kusz J, Nowak M. Synthesis, structure and cytotoxic activity of new acetylenic derivatives of betulin. Molecules. 2013 Apr 17; 18(4):4526-43. PMID: 23595090.
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    11. Tubek B, Mitula P, Niezgoda N, Kempinska K, Wietrzyk J, Wawrzenczyk C. Synthesis and cytotoxic activity of new betulin and betulinic acid esters with conjugated linoleic acid (CLA). Nat Prod Commun. 2013 Apr; 8(4):435-8. PMID: 23738445.
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