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    Karen Klein

    Address9500 Gilman Drive #0984
    CA La Jolla 92093
    Phone858-966-4032
    vCardDownload vCard

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Gravholt CH, Andersen NH, Conway GS, Dekkers OM, Geffner ME, Klein K, Lin AE, Mauras N, Quigley CA, Rubin K, Sandberg DE, Sas TCJ, Silberbach M, Söderström-Anttila V, Stochholm K, van Alfen-van derVelden JA, Woelfle J, Backeljauw PF. Clinical practice guidelines for the care of girls and women with Turner syndrome: proceedings from the 2016 Cincinnati International Turner Syndrome Meeting. Eur J Endocrinol. 2017 Sep; 177(3):G1-G70. PMID: 28705803.
        View in: PubMed
      2. Klein K, Yang J, Aisenberg J, Wright N, Kaplowitz P, Lahlou N, Linares J, Lundström E, Purcea D, Cassorla F. Efficacy and safety of triptorelin 6-month formulation in patients with central precocious puberty. J Pediatr Endocrinol Metab. 2016 Nov 01; 29(11):1241-1248. PMID: 26887034.
        View in: PubMed
      3. Klein K, Newfield RS, Hassink SG. Bone maturation along the spectrum from normal weight to obesity: a complex interplay of sex, growth factors and weight gain. J Pediatr Endocrinol Metab. 2016 Mar 1; 29(3):311-8. PMID: 26565541.
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      4. Pereira A, Corvalán C, Uauy R, Klein K, Mericq V. Ultrasensitive estrogen levels at 7 years of age predict earlier thelarche: evidence from girls of the growth and obesity Chilean cohort. Eur J Endocrinol. 2015 Dec; 173(6):835-42. PMID: 26369578.
        View in: PubMed
      5. Al-Zubeidi H, Klein K. Randomized clinical trial evaluating metformin versus oral contraceptive pills in the treatment of adolescents with polycystic ovarian syndrome. J Pediatr Endocrinol Metab. 2015 Jul; 28(7-8):853-8. PMID: 25781525.
        View in: PubMed
      6. Klein K. Is there a role for estrogen activity assays? Recombinant cell bioassay for estrogen: Development and applications. Steroids. 2015 Jul; 99(Pt A):108-12. PMID: 25159103.
        View in: PubMed
      7. Kletter GB, Klein K, Wong YY. A pediatrician's guide to central precocious puberty. Clin Pediatr (Phila). 2015 May; 54(5):414-24. PMID: 25022947.
        View in: PubMed
      8. Lee PA, Klein K, Mauras N, Lev-Vaisler T, Bacher P. 36-month treatment experience of two doses of leuprolide acetate 3-month depot for children with central precocious puberty. J Clin Endocrinol Metab. 2014 Sep; 99(9):3153-9. PMID: 24926950.
        View in: PubMed
      9. Lee PA, Klein K, Mauras N, Neely EK, Bloch CA, Larsen L, Mattia-Goldberg C, Chwalisz K. Efficacy and safety of leuprolide acetate 3-month depot 11.25 milligrams or 30 milligrams for the treatment of central precocious puberty. J Clin Endocrinol Metab. 2012 May; 97(5):1572-80. PMID: 22344198.
        View in: PubMed
      10. Taboada M, Santen R, Lima J, Hossain J, Singh R, Klein K, Mauras N. Pharmacokinetics and pharmacodynamics of oral and transdermal 17ß estradiol in girls with Turner syndrome. J Clin Endocrinol Metab. 2011 Nov; 96(11):3502-10. PMID: 21880799; PMCID: PMC3205885.
      11. Cohen D, Janfaza M, Klein K. Importance of leuprolide acetate variable dosing for precocious puberty: a range of acceptable suppression. J Pediatr Endocrinol Metab. 2009 Jul; 22(7):629-34. PMID: 19774844.
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      12. Mericq V, Lammoglia JJ, Unanue N, Villaroel C, Hernández MI, Avila A, Iñiguez G, Klein K. Comparison of three doses of leuprolide acetate in the treatment of central precocious puberty: preliminary results. Clin Endocrinol (Oxf). 2009 Nov; 71(5):686-90. PMID: 19302581.
        View in: PubMed
      13. Mauras N, Gonzalez de Pijem L, Hsiang HY, Desrosiers P, Rapaport R, Schwartz ID, Klein K, Singh RJ, Miyamoto A, Bishop K. Anastrozole increases predicted adult height of short adolescent males treated with growth hormone: a randomized, placebo-controlled, multicenter trial for one to three years. J Clin Endocrinol Metab. 2008 Mar; 93(3):823-31. PMID: 18165285; PMCID: PMC2266949.
      14. Kunz GJ, Sherman TI, Klein K. Luteinizing hormone (LH) and estradiol suppression and growth in girls with central precocious puberty: is more suppression better? Are pre-injection LH levels useful in monitoring treatment? J Pediatr Endocrinol Metab. 2007 Nov; 20(11):1189-98. PMID: 18183790.
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      15. Janfaza M, Sherman TI, Larmore KA, Brown-Dawson J, Klein K. Estradiol levels and secretory dynamics in normal girls and boys as determined by an ultrasensitive bioassay: a 10 year experience. J Pediatr Endocrinol Metab. 2006 Jul; 19(7):901-9. PMID: 16995570.
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      16. Badaru A, Wilson DM, Bachrach LK, Fechner P, Gandrud LM, Durham E, Wintergerst K, Chi C, Klein K, Neely EK. Sequential comparisons of one-month and three-month depot leuprolide regimens in central precocious puberty. J Clin Endocrinol Metab. 2006 May; 91(5):1862-7. PMID: 16449344.
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      17. Mauras N, Welch S, Rini A, Klein K. An open label 12-month pilot trial on the effects of the aromatase inhibitor anastrozole in growth hormone (GH)-treated GH deficient adolescent boys. J Pediatr Endocrinol Metab. 2004 Dec; 17(12):1597-606. PMID: 15645693.
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      18. Kunz GJ, Klein K, Clemons RD, Gottschalk ME, Jones KL. Virilization of young children after topical androgen use by their parents. Pediatrics. 2004 Jul; 114(1):282-4. PMID: 15231947.
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      19. Wilson CA, Heinrichs C, Larmore KA, Craen M, Brown-Dawson J, Shaywitz S, Ross J, Klein K. Estradiol levels in girls with Turner's syndrome compared to normal prepubertal girls as determined by an ultrasensitive assay. J Pediatr Endocrinol Metab. 2003 Jan; 16(1):91-6. PMID: 12585345.
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      20. Santen RJ, Pinkerton JV, Conaway M, Ropka M, Wisniewski L, Demers L, Klein K. Treatment of urogenital atrophy with low-dose estradiol: preliminary results. Menopause. 2002 May-Jun; 9(3):179-87. PMID: 11973441.
        View in: PubMed
      21. Larmore KA, O'Connor D, Sherman TI, Funanage VL, Hassink SG, Klein K. Leptin and estradiol as related to change in pubertal status and body weight. Med Sci Monit. 2002 Mar; 8(3):CR206-10. PMID: 11889458.
        View in: PubMed
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