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Joseph Wawrzyniak

TitlePostdoctoral Scholar
InstitutionUniversity of California San Diego
DepartmentPathology
Address9500 Gilman Drive #0695
La Jolla CA 92093
Phone858-822-5629
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    1. Bagati A, Bianchi-Smiraglia A, Moparthy S, Kolesnikova K, Fink EE, Lipchick BC, Kolesnikova M, Jowdy P, Polechetti A, Mahpour A, Ross J, Wawrzyniak JA, Yun DH, Paragh G, Kozlova NI, Berman AE, Wang J, Liu S, Nemeth MJ, Nikiforov MA. Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1. Cell Rep. 2017 Sep 19; 20(12):2820-2832. PMID: 28930679.
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    2. Zucker SN, Fink EE, Bagati A, Mannava S, Bianchi-Smiraglia A, Bogner PN, Wawrzyniak JA, Foley C, Leonova KI, Grimm MJ, Moparthy K, Ionov Y, Wang J, Liu S, Sexton S, Kandel ES, Bakin AV, Zhang Y, Kaminski N, Segal BH, Nikiforov MA. Nrf2 amplifies oxidative stress via induction of Klf9. Mol Cell. 2014 Mar 20; 53(6):916-928. PMID: 24613345; PMCID: PMC4049522.
    3. Wawrzyniak JA, Bianchi-Smiraglia A, Bshara W, Mannava S, Ackroyd J, Bagati A, Omilian AR, Im M, Fedtsova N, Miecznikowski JC, Moparthy KC, Zucker SN, Zhu Q, Kozlova NI, Berman AE, Hoek KS, Gudkov AV, Shewach DS, Morrison CD, Nikiforov MA. A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion. Cell Rep. 2013 Oct 31; 5(2):493-507. PMID: 24139804; PMCID: PMC3902135.
    4. Mannava S, Moparthy KC, Wheeler LJ, Leonova KI, Wawrzyniak JA, Bianchi-Smiraglia A, Berman AE, Flanagan S, Shewach DS, Zeitouni NC, Gudkov AV, Mathews CK, Nikiforov MA. Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion. Aging (Albany NY). 2012 Dec; 4(12):917-22. PMID: 23249808; PMCID: PMC3615158.
    5. Zucker SN, Zirnheld J, Bagati A, DiSanto TM, Des Soye B, Wawrzyniak JA, Etemadi K, Nikiforov M, Berezney R. Preferential induction of apoptotic cell death in melanoma cells as compared with normal keratinocytes using a non-thermal plasma torch. Cancer Biol Ther. 2012 Nov; 13(13):1299-306. PMID: 22895073; PMCID: PMC3493438.
    6. Mannava S, Zhuang D, Nair JR, Bansal R, Wawrzyniak JA, Zucker SN, Fink EE, Moparthy KC, Hu Q, Liu S, Boise LH, Lee KP, Nikiforov MA. KLF9 is a novel transcriptional regulator of bortezomib- and LBH589-induced apoptosis in multiple myeloma cells. Blood. 2012 Feb 09; 119(6):1450-8. PMID: 22144178; PMCID: PMC3286209.
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