Joseph Powers

Title(s)Postdoctoral Scholar, Bioengineering
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    University of Washignton, Seattle, WAPh.D.Bioengineering
    University of Minnesota, Minneapolis, MNM.S.Biomedical Engineering
    University of Minnesota, Minneapolis, MNB.Bm.E.Biomedical Engineering
    University of Wisconsin - La Crosse, La Crosse, WIB.S.Physics

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Dysregulated mechanosignaling in dilated cardiomyopathy caused by defective Filamin C
    NIH K99HL159224Sep 6, 2021 - Aug 31, 2023
    Role: Principal Investigator
    The role of cytoskeletal mechanotransduction and its regulation by Filamin C in pathological cardiac hypertrophy
    NIH F32HL152573May 7, 2020 - Jul 6, 2022
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Sliding Filament Theory Since Andrew Huxley: Multiscale and Multidisciplinary Muscle Research. Annu Rev Biophys. 2021 05 06; 50:373-400. Powers JD, Malingen SA, Regnier M, Daniel TL. PMID: 33637009.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. The effect of variable troponin C mutation thin filament incorporation on cardiac muscle twitch contractions. J Mol Cell Cardiol. 2021 06; 155:112-124. Mijailovich SM, Prodanovic M, Poggesi C, Powers JD, Davis J, Geeves MA, Regnier M. PMID: 33636222.
      View in: PubMed   Mentions:    Fields:    
    3. Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts. JCI Insight. 2020 10 15; 5(20). Powers JD, Kooiker KB, Mason AB, Teitgen AE, Flint GV, Tardiff JC, Schwartz SD, McCulloch AD, Regnier M, Davis J, Moussavi-Harami F. PMID: 32931484.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    4. Contracting striated muscle has a dynamic I-band spring with an undamped stiffness 100 times larger than the passive stiffness. J Physiol. 2020 01; 598(2):331-345. Powers JD, Bianco P, Pertici I, Reconditi M, Lombardi V, Piazzesi G. PMID: 31786814.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    5. Multiscale Models of Cardiac Muscle Biophysics and Tissue Remodeling in Hypertrophic Cardiomyopathies. Curr Opin Biomed Eng. 2019 Sep; 11:35-44. Aboelkassem Y, Powers JD, McCabe KJ, McCulloch AD. PMID: 31886450.
      View in: PubMed   Mentions: 1  
    6. Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin. Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11502-11507. Powers JD, Yuan CC, McCabe KJ, Murray JD, Childers MC, Flint GV, Moussavi-Harami F, Mohran S, Castillo R, Zuzek C, Ma W, Daggett V, McCulloch AD, Irving TC, Regnier M. PMID: 31110001.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    7. Inotropic interventions do not change the resting state of myosin motors during cardiac diastole. J Gen Physiol. 2019 01 07; 151(1):53-65. Caremani M, Pinzauti F, Powers JD, Governali S, Narayanan T, Stienen GJM, Reconditi M, Linari M, Lombardi V, Piazzesi G. PMID: 30510036; PMCID: PMC6314382.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    8. A Spatially Explicit Model Shows How Titin Stiffness Modulates Muscle Mechanics and Energetics. . 2018 08 01; 58(2):186-193. Powers JD, Williams CD, Regnier M, Daniel TL. PMID: 29897447; PMCID: PMC6104699.
      View in: PubMed   Mentions: 7  Translation:HumansAnimals
    9. Afterload promotes maturation of human induced pluripotent stem cell derived cardiomyocytes in engineered heart tissues. J Mol Cell Cardiol. 2018 05; 118:147-158. Hanna RF, Ward TJ, Chow DS, Lagana SM, Moreira RK, Emond JC, Weintraub JL, Prince MR, Leonard A, Bertero A, Powers JD, Beussman KM, Bhandari S, Regnier M, Murry CE, Sniadecki NJ. PMID: 29604261; PMCID: PMC5940558.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    10. Myosin filament activation in the heart is tuned to the mechanical task. Proc Natl Acad Sci U S A. 2017 03 21; 114(12):3240-3245. Reconditi M, Caremani M, Pinzauti F, Powers JD, Narayanan T, Stienen GJ, Linari M, Lombardi V, Piazzesi G. PMID: 28265101; PMCID: PMC5373356.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    11. Minimum number of myosin motors accounting for shortening velocity under zero load in skeletal muscle. J Physiol. 2017 02 15; 595(4):1127-1142. Fusi L, Percario V, Brunello E, Caremani M, Bianco P, Powers JD, Reconditi M, Lombardi V, Piazzesi G. PMID: 27763660.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    12. The predicted role of steric specificity in crowding-mediated effects on reversible biomolecular association. Phys Biol. 2015 Nov 23; 12(6):066004. Powers JD, Castle BT, Odde DJ, Powers JD, Castle BT, Odde DJ. PMID: 26595211.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
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