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Jong Rho

Title(s)Professor, Neurosciences
SchoolHealth Sciences
Address9300 Campus Point Drive #7950
La Jolla CA 92037
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    Mechanisms of Seizure Genesis in Human Hypothalamic Hamartomas
    NIH/NINDS R21NS057786Apr 1, 2008 - Mar 31, 2011
    Role: Principal Investigator
    International Symposium on Dietary Therapies for Epilepsy and Other Neurological
    NIH/NINDS R13NS062642Apr 1, 2008 - Mar 31, 2009
    Role: Principal Investigator
    GABAergic Inhibition and the Ketogenic Diet
    NIH/NINDS K02NS044846Feb 1, 2003 - Jun 30, 2004
    Role: Principal Investigator
    POTASSIUM CHANNELS AND EPILEPTOGENESIS
    NIH/NINDS K08NS001974Jul 23, 1997 - Sep 30, 2000
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Atypical visual processing in a mouse model of autism. Sci Rep. 2020 Jul 24; 10(1):12390. Cheng N, Pagtalunan E, Abushaibah A, Naidu J, Stell WK, Rho JM, Sauvé Y. PMID: 32709898.
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    2. Metabolic Epilepsies Amenable to Ketogenic Therapies: Indications, Contra-indications and Underlying Mechanisms. J Inherit Metab Dis. 2020 Jul 12. Gavrilovici C, Rho JM. PMID: 32654164.
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    3. FMRP(1-297)-tat restores ion channel and synaptic function in a model of Fragile X syndrome. Nat Commun. 2020 Jun 02; 11(1):2755. Zhan X, Asmara H, Cheng N, Sahu G, Sanchez E, Zhang FX, Zamponi GW, Rho JM, Turner RW. PMID: 32488011.
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    4. Aberrant Mitochondrial Morphology and Function in the BTBR Mouse Model of Autism Is Improved by Two Weeks of Ketogenic Diet. Int J Mol Sci. 2020 May 05; 21(9). Ahn Y, Sabouny R, Villa BR, Yee NC, Mychasiuk R, Uddin GM, Rho JM, Shutt TE. PMID: 32380723.
      View in: PubMed   Mentions:    Fields:    
    5. Reelin Improves Cognition and Extends the Lifespan of Mutant Ndel1 Mice with Postnatal CA1 Hippocampus Deterioration. Cereb Cortex. 2020 Apr 24. Kiroski I, Jiang Y, Gavrilovici C, Gao F, Lee S, Scantlebury MH, Vandal M, Park SK, Tsai LH, Teskey GC, Rho JM, Nguyen MD. PMID: 32328622.
      View in: PubMed   Mentions:    Fields:    
    6. Metabolism-based drug discovery in zebrafish: An emerging strategy to uncover new anti-seizure therapies. Neuropharmacology. 2020 May 01; 167:107988. Ibhazehiebo K, Rho JM, Kurrasch DM. PMID: 32070912.
      View in: PubMed   Mentions: 1     Fields:    
    7. Metabolic Framework for the Improvement of Autism Spectrum Disorders by a Modified Ketogenic Diet: A Pilot Study. J Proteome Res. 2020 01 03; 19(1):382-390. Mu C, Corley MJ, Lee RWY, Wong M, Pang A, Arakaki G, Miyamoto R, Rho JM, Mickiewicz B, Dowlatabadi R, Vogel HJ, Korchemagin Y, Shearer J. PMID: 31696714.
      View in: PubMed   Mentions:    Fields:    
    8. Position Statement on the Use of Medical Cannabis for the Treatment of Epilepsy in Canada. Can J Neurol Sci. 2019 11; 46(6):645-652. Appendino JP, Boelman C, Brna PM, Burneo JG, Claassen CS, Connolly MB, De Guzman MVT, Federico P, Floyd D, Huntsman RJ, Javidan M, Jette N, Jurasek LL, Keezer MR, Lau JC, McCoy B, McLachlan RS, Ng MC, Nguyen DK, Reid AY, Rho JM, Snead OC, Téllez-Zenteno JF, Wang L, Zak MM. PMID: 31466531.
      View in: PubMed   Mentions:    Fields:    
    9. Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives. Front Neurosci. 2019; 13:1041. Poff AM, Rho JM, D'Agostino DP. PMID: 31680801.
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    10. Precocious myelination in a mouse model of autism. Transl Psychiatry. 2019 10 07; 9(1):251. Khanbabaei M, Hughes E, Ellegood J, Qiu LR, Yip R, Dobry J, Murari K, Lerch JP, Rho JM, Cheng N. PMID: 31591392.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    11. Epigenetics and epilepsy prevention: The therapeutic potential of adenosine and metabolic therapies. Neuropharmacology. 2020 May 01; 167:107741. Boison D, Rho JM. PMID: 31419398.
      View in: PubMed   Mentions: 2     Fields:    
    12. Single-center experience with Beta-propeller protein-associated neurodegeneration (BPAN); expanding the phenotypic spectrum. Mol Genet Metab Rep. 2019 Sep; 20:100483. Chard M, Appendino JP, Bello-Espinosa LE, Curtis C, Rho JM, Wei XC, Al-Hertani W. PMID: 31293896.
      View in: PubMed   Mentions:
    13. Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosis. J Clin Invest. 2019 05 21; 129(8):3277-3292. Kaushik DK, Bhattacharya A, Mirzaei R, Rawji KS, Ahn Y, Rho JM, Yong VW. PMID: 31112527.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    14. Highlights From the Annual Meeting of the American Epilepsy Society 2018. Epilepsy Curr. 2019 May-Jun; 19(3):152-158. Jobst BC, Ben-Menachem E, Chapman KE, Fu A, Goldman A, Hirsch LJ, Jehi LE, Kossoff EH, Plueger M, Rho JM, Schevon CA, Shinnar S, Sperling MR, Simeone TA, Wagner JL, Lado F. PMID: 31050308.
      View in: PubMed   Mentions:
    15. 2-Deoxyglucose and Beta-Hydroxybutyrate: Metabolic Agents for Seizure Control. Front Cell Neurosci. 2019; 13:172. Rho JM, Shao LR, Stafstrom CE. PMID: 31114484.
      View in: PubMed   Mentions:
    16. Brief history of anti-seizure drug development. Epilepsia Open. 2018 Dec; 3(Suppl Suppl 2):114-119. Rho JM, White HS. PMID: 30564769.
      View in: PubMed   Mentions:
    17. Glycolytic inhibition: A novel approach toward controlling neuronal excitability and seizures. Epilepsia Open. 2018 Dec; 3(Suppl Suppl 2):191-197. Shao LR, Rho JM, Stafstrom CE. PMID: 30564778.
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    18. Altered circadian rhythms and oscillation of clock genes and sirtuin 1 in a model of sudden unexpected death in epilepsy. Epilepsia. 2018 08; 59(8):1527-1539. Wallace E, Wright S, Schoenike B, Roopra A, Rho JM, Maganti RK. PMID: 30009381.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    19. Infantile Epileptic Encephalopathy With Multiple Genetic Mutations: How Important are Variants of Undetermined Significance? Semin Pediatr Neurol. 2018 07; 26:33-36. Almomen M, Rho JM, Scantlebury MH. PMID: 29961513.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Metabolism and epilepsy: Ketogenic diets as a homeostatic link. Brain Res. 2019 01 15; 1703:26-30. Masino SA, Rho JM. PMID: 29883626.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Comorbid epilepsy in autism spectrum disorder: Implications of postnatal inflammation for brain excitability. Epilepsia. 2018 07; 59(7):1316-1326. Lewis ML, Kesler M, Candy SA, Rho JM, Pittman QJ. PMID: 29858515.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    22. Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group. Epilepsia Open. 2018 Jun; 3(2):175-192. Kossoff EH, Zupec-Kania BA, Auvin S, Ballaban-Gil KR, Christina Bergqvist AG, Blackford R, Buchhalter JR, Caraballo RH, Cross JH, Dahlin MG, Donner EJ, Guzel O, Jehle RS, Klepper J, Kang HC, Lambrechts DA, Liu YMC, Nathan JK, Nordli DR, Pfeifer HH, Rho JM, Scheffer IE, Sharma S, Stafstrom CE, Thiele EA, Turner Z, Vaccarezza MM, van der Louw EJTM, Veggiotti P, Wheless JW, Wirrell EC. PMID: 29881797.
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    23. Electrophysiological characterization of a mitochondrial inner membrane chloride channel in rat brain. FEBS Lett. 2018 05; 592(9):1545-1553. Drummond-Main CD, Rho JM. PMID: 29578588.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    24. A novel metabolism-based phenotypic drug discovery platform in zebrafish uncovers HDACs 1 and 3 as a potential combined anti-seizure drug target. Brain. 2018 03 01; 141(3):744-761. Ibhazehiebo K, Gavrilovici C, de la Hoz CL, Ma SC, Rehak R, Kaushik G, Meza Santoscoy PL, Scott L, Nath N, Kim DY, Rho JM, Kurrasch DM. PMID: 29373639.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    25. ER-stress mobilization of death-associated protein kinase-1-dependent xenophagy counteracts mitochondria stress-induced epithelial barrier dysfunction. J Biol Chem. 2018 03 02; 293(9):3073-3087. Lopes F, Keita ÅV, Saxena A, Reyes JL, Mancini NL, Al Rajabi A, Wang A, Baggio CH, Dicay M, van Dalen R, Ahn Y, Carneiro MBH, Peters NC, Rho JM, MacNaughton WK, Girardin SE, Jijon H, Philpott DJ, Söderholm JD, McKay DM. PMID: 29317503.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    26. Do ketone bodies mediate the anti-seizure effects of the ketogenic diet? Neuropharmacology. 2018 05 01; 133:233-241. Simeone TA, Simeone KA, Stafstrom CE, Rho JM. PMID: 29325899.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    27. Ketogenic diet-induced extension of longevity in epileptic Kcna1-null mice is influenced by gender and age at treatment onset. Epilepsy Res. 2018 02; 140:53-55. Chun KC, Ma SC, Oh H, Rho JM, Kim DY. PMID: 29245026.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    28. Clinical studies and anti-inflammatory mechanisms of treatments. Epilepsia. 2017 07; 58 Suppl 3:69-82. French JA, Koepp M, Naegelin Y, Vigevano F, Auvin S, Rho JM, Rosenberg E, Devinsky O, Olofsson PS, Dichter MA. PMID: 28675558.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    29. Dendritic overgrowth and elevated ERK signaling during neonatal development in a mouse model of autism. PLoS One. 2017; 12(6):e0179409. Cheng N, Alshammari F, Hughes E, Khanbabaei M, Rho JM. PMID: 28609458.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    30. The relationship between d-beta-hydroxybutyrate blood concentrations and seizure control in children treated with the ketogenic diet for medically intractable epilepsy. Epilepsia Open. 2017 09; 2(3):317-321. Buchhalter JR, D'Alfonso S, Connolly M, Fung E, Michoulas A, Sinasac D, Singer R, Smith J, Singh N, Rho JM. PMID: 29588960.
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    31. Ketogenic diet leads to O-GlcNAc modification in the BTBRT+tf/j mouse model of autism. Biochim Biophys Acta Mol Basis Dis. 2017 09; 1863(9):2274-2281. Newell C, Johnsen VL, Yee NC, Xu WJ, Klein MS, Khan A, Rho JM, Shearer J. PMID: 28502704.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    32. Need for new review of article on ketogenic dietary regimes for cancer patients. Med Oncol. 2017 06; 34(6):108. Klement RJ, Feinman RD, Gross EC, Champ CE, D'Agostino DP, Fine EJ, Kämmerer U, Poff A, Rho JM, Seyfried TN, Scheck AC. PMID: 28452037.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    33. Ketone Bodies as Anti-Seizure Agents. Neurochem Res. 2017 Jul; 42(7):2011-2018. Simeone TA, Simeone KA, Rho JM. PMID: 28397070.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    34. Abnormal Capillary Vasodynamics Contribute to Ictal Neurodegeneration in Epilepsy. Sci Rep. 2017 02 27; 7:43276. Leal-Campanario R, Alarcon-Martinez L, Rieiro H, Martinez-Conde S, Alarcon-Martinez T, Zhao X, LaMee J, Popp PJ, Calhoun ME, Arribas JI, Schlegel AA, Stasi LL, Rho JM, Inge L, Otero-Millan J, Treiman DM, Macknik SL. PMID: 28240297.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    35. Adrenocorticotropic hormone protects learning and memory function in epileptic Kcna1-null mice. Neurosci Lett. 2017 04 03; 645:14-18. Scantlebury MH, Chun KC, Ma SC, Rho JM, Kim DY. PMID: 28249786.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    36. Carisbamate blockade of T-type voltage-gated calcium channels. Epilepsia. 2017 04; 58(4):617-626. Kim DY, Zhang FX, Nakanishi ST, Mettler T, Cho IH, Ahn Y, Hiess F, Chen L, Sullivan PG, Chen SR, Zamponi GW, Rho JM. PMID: 28230232.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    37. Metabolic Dysfunction Underlying Autism Spectrum Disorder and Potential Treatment Approaches. Front Mol Neurosci. 2017; 10:34. Cheng N, Rho JM, Masino SA. PMID: 28270747.
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    38. Tissue Specific Impacts of a Ketogenic Diet on Mitochondrial Dynamics in the BTBRT+tf/j Mouse. Front Physiol. 2016; 7:654. Newell C, Shutt TE, Ahn Y, Hittel DS, Khan A, Rho JM, Shearer J. PMID: 28082920.
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    39. Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder. Mol Autism. 2016; 7(1):37. Newell C, Bomhof MR, Reimer RA, Hittel DS, Rho JM, Shearer J. PMID: 27594980.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    40. Disruption of visual circuit formation and refinement in a mouse model of autism. Autism Res. 2017 Feb; 10(2):212-223. Cheng N, Khanbabaei M, Murari K, Rho JM. PMID: 27529416.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    41. Genetic modifications associated with ketogenic diet treatment in the BTBRT+Tf/J mouse model of autism spectrum disorder. Autism Res. 2017 Mar; 10(3):456-471. Mychasiuk R, Rho JM. PMID: 27529337.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    42. Ketogenic diet treatment increases longevity in Kcna1-null mice, a model of sudden unexpected death in epilepsy. Epilepsia. 2016 08; 57(8):e178-82. Simeone KA, Matthews SA, Rho JM, Simeone TA. PMID: 27346881.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    43. Ndel1 and Reelin Maintain Postnatal CA1 Hippocampus Integrity. J Neurosci. 2016 06 15; 36(24):6538-52. Jiang Y, Gavrilovici C, Chansard M, Liu RH, Kiroski I, Parsons K, Park SK, Teskey GC, Rho JM, Nguyen MD. PMID: 27307241.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    44. Mechanisms of Action of Antiseizure Drugs and the Ketogenic Diet. Cold Spring Harb Perspect Med. 2016 05 02; 6(5). Rogawski MA, Löscher W, Rho JM. PMID: 26801895.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    45. Metabolomic Modeling To Monitor Host Responsiveness to Gut Microbiota Manipulation in the BTBR(T+tf/j) Mouse. J Proteome Res. 2016 Apr 01; 15(4):1143-50. Klein MS, Newell C, Bomhof MR, Reimer RA, Hittel DS, Rho JM, Vogel HJ, Shearer J. PMID: 26928523.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    46. Ketogenic diet restores aberrant cortical motor maps and excitation-to-inhibition imbalance in the BTBR mouse model of autism spectrum disorder. Behav Brain Res. 2016 May 01; 304:67-70. Smith J, Rho JM, Teskey GC. PMID: 26876011.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    47. Teaching NeuroImages: MRI findings in X-linked adrenoleukodystrophy. Neurology. 2015 Oct 27; 85(17):e132-3. Myers KA, Rho JM, Wei XC. PMID: 26503591.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. How does the ketogenic diet induce anti-seizure effects? Neurosci Lett. 2017 01 10; 637:4-10. Rho JM. PMID: 26222258.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    49. Inhibition of Lactate Dehydrogenase to Treat Epilepsy. N Engl J Med. 2015 Jul 09; 373(2):187-9. Rho JM. PMID: 26154793.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    50. "Tinkle Tinkle Little Girl, How We Wonder Why You Can't": An Unusual AIDP-like Syndrome in a Toddler. Can J Neurol Sci. 2015 Jul; 42(4):274-7. Rajapakse T, Hinnell CJ, Wei XC, Mah JK, Rho JM. PMID: 25990009.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Differential effects of duration of sleep fragmentation on spatial learning and synaptic plasticity in pubertal mice. Brain Res. 2015 Jul 30; 1615:116-128. Wallace E, Kim DY, Kim KM, Chen S, Blair Braden B, Williams J, Jasso K, Garcia A, Rho JM, Bimonte-Nelson H, Maganti R. PMID: 25957790.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    52. Ketone bodies mediate antiseizure effects through mitochondrial permeability transition. Ann Neurol. 2015 Jul; 78(1):77-87. Kim DY, Simeone KA, Simeone TA, Pandya JD, Wilke JC, Ahn Y, Geddes JW, Sullivan PG, Rho JM. PMID: 25899847.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    53. Stoichiometric expression of mtHsp40 and mtHsp70 modulates mitochondrial morphology and cristae structure via Opa1L cleavage. Mol Biol Cell. 2015 Jun 15; 26(12):2156-67. Lee B, Ahn Y, Kang SM, Park Y, Jeon YJ, Rho JM, Kim SW. PMID: 25904328.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    54. Ketones prevent oxidative impairment of hippocampal synaptic integrity through KATP channels. PLoS One. 2015; 10(4):e0119316. Kim DY, Abdelwahab MG, Lee SH, O'Neill D, Thompson RJ, Duff HJ, Sullivan PG, Rho JM. PMID: 25848768.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    55. Efficacy of intravenous immunoglobulin in a cohort of children with drug-resistant epilepsy. Pediatr Neurol. 2015 May; 52(5):509-16. Bello-Espinosa LE, Rajapakse T, Rho JM, Buchhalter J. PMID: 25882078.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    56. Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid. Acta Neuropathol Commun. 2015 Jan 20; 3:3. Nicolini C, Ahn Y, Michalski B, Rho JM, Fahnestock M. PMID: 25627160.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    57. The New Ketone Alphabet Soup: BHB, HCA, and HDAC. Epilepsy Curr. 2014 Nov-Dec; 14(6):355-7. Hartman AL, Rho JM. PMID: 25678874.
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    58. The ketogenic diet modifies social and metabolic alterations identified in the prenatal valproic acid model of autism spectrum disorder. Dev Neurosci. 2014; 36(5):371-80. Ahn Y, Narous M, Tobias R, Rho JM, Mychasiuk R. PMID: 25011527.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    59. Inchworming: a novel motor stereotypy in the BTBR T+ Itpr3tf/J mouse model of autism. J Vis Exp. 2014 Jul 05; (89). Smith JD, Rho JM, Masino SA, Mychasiuk R. PMID: 25046063.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    60. Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels. Mol Brain. 2014 May 31; 7:42. Stotz SC, Scott LO, Drummond-Main C, Avchalumov Y, Girotto F, Davidsen J, Gómez-Gárcia MR, Rho JM, Pavlov EV, Colicos MA. PMID: 24886461.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    61. Ketogenic diets, mitochondria, and neurological diseases. J Lipid Res. 2014 Nov; 55(11):2211-28. Gano LB, Patel M, Rho JM. PMID: 24847102.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    62. How is homeostatic plasticity important in epilepsy? Adv Exp Med Biol. 2014; 813:123-31. Swann JW, Rho JM. PMID: 25012372.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    63. Ketogenic diet improves core symptoms of autism in BTBR mice. PLoS One. 2013; 8(6):e65021. Ruskin DN, Svedova J, Cote JL, Sandau U, Rho JM, Kawamura M, Boison D, Masino SA. PMID: 23755170.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    64. Loss of the Kv1.1 potassium channel promotes pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices. Neurobiol Dis. 2013 Jun; 54:68-81. Simeone TA, Simeone KA, Samson KK, Kim DY, Rho JM. PMID: 23466697.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    65. Unilateral foot drop as an initial presentation of a brain tumor in a child. J Child Neurol. 2014 Jul; 29(7):955-8. Goia E, Hamilton L, Chan J, Wei XC, Mah JK, Rho JM. PMID: 23456535.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    66. High dose folic acid supplementation of rats alters synaptic transmission and seizure susceptibility in offspring. Sci Rep. 2013; 3:1465. Girotto F, Scott L, Avchalumov Y, Harris J, Iannattone S, Drummond-Main C, Tobias R, Bello-Espinosa L, Rho JM, Davidsen J, Teskey GC, Colicos MA. PMID: 23492951.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    67. Sweets Are BAD for Seizures. Epilepsy Curr. 2012 Nov; 12(6):218-9. Patel M, Rho JM. PMID: 23447715.
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    68. Finding a better drug for epilepsy: antiepileptogenesis targets. Epilepsia. 2012 Nov; 53(11):1868-76. Kobow K, Auvin S, Jensen F, Löscher W, Mody I, Potschka H, Prince D, Sierra A, Simonato M, Pitkänen A, Nehlig A, Rho JM. PMID: 23061663.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    69. Inflammation-mediated memory dysfunction and effects of a ketogenic diet in a murine model of multiple sclerosis. PLoS One. 2012; 7(5):e35476. Kim DY, Hao J, Liu R, Turner G, Shi FD, Rho JM. PMID: 22567104.
      View in: PubMed   Mentions: 46     Fields:    Translation:Animals
    70. The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma. PLoS One. 2012; 7(5):e36197. Abdelwahab MG, Fenton KE, Preul MC, Rho JM, Lynch A, Stafford P, Scheck AC. PMID: 22563484.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimals
    71. The ketogenic diet as a treatment paradigm for diverse neurological disorders. Front Pharmacol. 2012; 3:59. Stafstrom CE, Rho JM. PMID: 22509165.
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    72. Adenosine: a fundamental factor formed from Fatty feasts for fighting fits? Epilepsy Curr. 2012 Jan; 12(1):19-21. Rho JM. PMID: 22368522.
      View in: PubMed   Mentions:
    73. The ketogenic diet: what has science taught us? Epilepsy Res. 2012 Jul; 100(3):210-7. Rho JM, Stafstrom CE. PMID: 21856126.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    74. Ketogenic diet in the treatment of seizures associated with hypothalamic hamartomas. Epilepsy Res. 2011 May; 94(3):218-21. Chapman KE, Kim DY, Rho JM, Ng YT, Kerrigan JF. PMID: 21377333.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    75. Pediatric stroke. Childs Nerv Syst. 2011 Sep; 27(9):1375-90. Cárdenas JF, Rho JM, Kirton A. PMID: 21336993.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    76. L-Type calcium channel blockade reduces network activity in human epileptic hypothalamic hamartoma tissue. Epilepsia. 2011 Mar; 52(3):531-40. Simeone KA, Sabesan S, Kim DY, Kerrigan JF, Rho JM, Simeone TA. PMID: 21269296.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    77. Pediatric neuropharmacotherapeutics. Introduction. Semin Pediatr Neurol. 2010 Dec; 17(4):207. Pinter JD, Rho JM. PMID: 21183125.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    78. How does altered metabolism lead to seizure control? Partially filling the knowledge gap. Epilepsy Curr. 2010 Nov; 10(6):159-61. Rho JM. PMID: 21157545.
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    79. The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma. Nutr Metab (Lond). 2010 Sep 10; 7:74. Stafford P, Abdelwahab MG, Kim DY, Preul MC, Rho JM, Scheck AC. PMID: 20831808.
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    80. Another Look at Early GABAergic Neurotransmission: Maybe It's Not So Exciting After All! Epilepsy Curr. 2010 Sep; 10(5):128-30. Rho JM. PMID: 20944825.
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    81. Ketones prevent synaptic dysfunction induced by mitochondrial respiratory complex inhibitors. J Neurochem. 2010 Jul; 114(1):130-41. Kim DY, Vallejo J, Rho JM. PMID: 20374433.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    82. A "happy" toddler presenting with sudden, life-threatening seizures. Semin Pediatr Neurol. 2010 Mar; 17(1):35-8. Stein D, Chetty M, Rho JM. PMID: 20434691.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    83. Anticonvulsant effects of the selective melatonin receptor agonist ramelteon. Epilepsy Behav. 2009 Sep; 16(1):52-7. Fenoglio-Simeone K, Mazarati A, Sefidvash-Hockley S, Shin D, Wilke J, Milligan H, Sankar R, Rho JM, Maganti R. PMID: 19682955.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    84. Ketogenic diets: an update for child neurologists. J Child Neurol. 2009 Aug; 24(8):979-88. Kossoff EH, Zupec-Kania BA, Rho JM. PMID: 19535814.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    85. Reversible lamotrigine-induced neurobehavioral disturbances in children with epilepsy. J Child Neurol. 2010 Feb; 25(2):182-7. Cardenas JF, Rho JM, Ng YT. PMID: 19494356.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    86. Ketogenic diet treatment abolishes seizure periodicity and improves diurnal rhythmicity in epileptic Kcna1-null mice. Epilepsia. 2009 Sep; 50(9):2027-34. Fenoglio-Simeone KA, Wilke JC, Milligan HL, Allen CN, Rho JM, Maganti RK. PMID: 19490051.
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    87. Ketogenic diets: evidence for short- and long-term efficacy. Neurotherapeutics. 2009 Apr; 6(2):406-14. Kossoff EH, Rho JM. PMID: 19332337.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    88. Arresting a seizure by dropping a little Acid. Epilepsy Curr. 2009 Mar-Apr; 9(2):55-6. Rho JM. PMID: 19421382.
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    89. Bicarbonate contributes to GABAA receptor-mediated neuronal excitation in surgically resected human hypothalamic hamartomas. Epilepsy Res. 2009 Jan; 83(1):89-93. Kim DY, Fenoglio KA, Kerrigan JF, Rho JM. PMID: 19022626.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    90. Oxidative impairment of hippocampal long-term potentiation involves activation of protein phosphatase 2A and is prevented by ketone bodies. J Neurosci Res. 2008 Nov 15; 86(15):3322-30. Maalouf M, Rho JM. PMID: 18646208.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    91. The ketogenic diet in a pill: is this possible? Epilepsia. 2008 Nov; 49 Suppl 8:127-33. Rho JM, Sankar R. PMID: 19049610.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    92. Epilepsia. Ketogenic diet and treatments. Introduction/perspectives. Epilepsia. 2008 Nov; 49 Suppl 8:1-2. Stafstrom CE, Zupec-Kania B, Rho JM. PMID: 19049573.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    93. UCP-mediated free fatty acid uncoupling of isolated cortical mitochondria from fasted animals: correlations to dietary modulations. Epilepsia. 2008 Nov; 49 Suppl 8:117-9. Davis LM, Rho JM, Sullivan PG. PMID: 19049607.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    94. The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies. Brain Res Rev. 2009 Mar; 59(2):293-315. Maalouf M, Rho JM, Mattson MP. PMID: 18845187.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansAnimalsCells
    95. Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group. Epilepsia. 2009 Feb; 50(2):304-17. Kossoff EH, Zupec-Kania BA, Amark PE, Ballaban-Gil KR, Christina Bergqvist AG, Blackford R, Buchhalter JR, Caraballo RH, Helen Cross J, Dahlin MG, Donner EJ, Klepper J, Jehle RS, Kim HD, Christiana Liu YM, Nation J, Nordli DR, Pfeifer HH, Rho JM, Stafstrom CE, Thiele EA, Turner Z, Wirrell EC, Wheless JW, Veggiotti P, Vining EP. PMID: 18823325.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    96. GABA(A) receptor-mediated excitation in dissociated neurons from human hypothalamic hamartomas. Exp Neurol. 2008 Oct; 213(2):397-404. Wu J, DeChon J, Xue F, Li G, Ellsworth K, Gao M, Liu Q, Yang K, Zheng C, He P, Tu J, Kim DY, Rho JM, Rekate H, Kerrigan JF, Chang Y. PMID: 18675803.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    97. Fasting is neuroprotective following traumatic brain injury. J Neurosci Res. 2008 Jun; 86(8):1812-22. Davis LM, Pauly JR, Readnower RD, Rho JM, Sullivan PG. PMID: 18241053.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    98. Can reducing sugar retard kindling? Epilepsy Curr. 2008 May-Jun; 8(3):83-4. Rho JM. PMID: 18488064.
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    99. The ketogenic diet and epilepsy. Curr Opin Clin Nutr Metab Care. 2008 Mar; 11(2):113-20. Kim DY, Rho JM. PMID: 18301085.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    100. GABAA receptor-mediated activation of L-type calcium channels induces neuronal excitation in surgically resected human hypothalamic hamartomas. Epilepsia. 2008 May; 49(5):861-71. Kim DY, Fenoglio KA, Simeone TA, Coons SW, Wu J, Chang Y, Kerrigan JF, Rho JM. PMID: 18076645.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    101. Substantia(ting) ketone body effects on neuronal excitability. Epilepsy Curr. 2007 Sep-Oct; 7(5):142-4. Rho JM. PMID: 17998978.
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    102. Hypothalamic hamartoma: basic mechanisms of intrinsic epileptogenesis. Semin Pediatr Neurol. 2007 Jun; 14(2):51-9. Fenoglio KA, Wu J, Kim DY, Simeone TA, Coons SW, Rekate H, Rho JM, Kerrigan JF. PMID: 17544947.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    103. Do seizures affect the developing brain? Lessons from the laboratory. J Child Neurol. 2007 May; 22(5 Suppl):21S-9S. Sankar R, Rho JM. PMID: 17690084.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    104. Electrophysiological properties and subunit composition of GABAA receptors in patients with gelastic seizures and hypothalamic hamartoma. J Neurophysiol. 2007 Jul; 98(1):5-15. Wu J, Chang Y, Li G, Xue F, DeChon J, Ellsworth K, Liu Q, Yang K, Bahadroani N, Zheng C, Zhang J, Rekate H, Rho JM, Kerrigan JF. PMID: 17428906.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    105. Ketone bodies are protective against oxidative stress in neocortical neurons. J Neurochem. 2007 Jun; 101(5):1316-26. Kim DY, Davis LM, Sullivan PG, Maalouf M, Simeone TA, van Brederode J, Rho JM. PMID: 17403035.
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    106. The ketogenic diet: stoking the powerhouse of the cell. Epilepsy Curr. 2007 Mar-Apr; 7(2):58-60. Rho JM, Rogawski MA. PMID: 17505556.
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    107. Anticonvulsant mechanisms of the ketogenic diet. Epilepsia. 2007 Jan; 48(1):43-58. Bough KJ, Rho JM. PMID: 17241207.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    108. Impaired motor control in patients with benign focal epilepsy of childhood. J Child Neurol. 2006 Feb; 21(2):157-60. Maalouf M, Takahashi CD, Reinkensmeyer DJ, Cooper DM, Rho JM. PMID: 16566883.
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    109. Electrophysiological properties of human hypothalamic hamartomas. Ann Neurol. 2005 Sep; 58(3):371-82. Wu J, Xu L, Kim DY, Rho JM, St John PA, Lue LF, Coons S, Ellsworth K, Nowak L, Johnson E, Rekate H, Kerrigan JF. PMID: 16130091.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    110. Clinical experience with zonisamide monotherapy and adjunctive therapy in children with epilepsy at a tertiary care referral center. J Child Neurol. 2005 Mar; 20(3):212-9. Kim HL, Aldridge J, Rho JM. PMID: 15832611.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    111. A cDNA microarray analysis of gene expression profiles in rat hippocampus following a ketogenic diet. Brain Res Mol Brain Res. 2004 Oct 22; 129(1-2):80-7. Noh HS, Lee HP, Kim DW, Kang SS, Cho GJ, Rho JM, Choi WS. PMID: 15469884.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    112. Lack of long-term histopathologic changes in brain and skeletal muscle of mice treated with a ketogenic diet. J Child Neurol. 2004 Jul; 19(7):555-7. Rho JM, Sarnat HB, Sullivan PG, Robbins CA, Kim DW. PMID: 15526964.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    113. Molecular biology and ontogeny of glutamate receptors in the mammalian central nervous system. J Child Neurol. 2004 May; 19(5):343-60; discussion 361. Simeone TA, Sanchez RM, Rho JM. PMID: 15224708.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    114. The ketogenic diet increases mitochondrial uncoupling protein levels and activity. Ann Neurol. 2004 Apr; 55(4):576-80. Sullivan PG, Rippy NA, Dorenbos K, Concepcion RC, Agarwal AK, Rho JM. PMID: 15048898.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    115. Basic science behind the catastrophic epilepsies. Epilepsia. 2004; 45 Suppl 5:5-11. Rho JM. PMID: 15283705.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    116. Voltage-dependent block of N-methyl-D-aspartate receptors by the novel anticonvulsant dibenzylamine, a bioactive constituent of L-(+)-beta-hydroxybutyrate. Epilepsia. 2003 Oct; 44(10):1274-9. Donevan SD, White HS, Anderson GD, Rho JM. PMID: 14510820.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    117. Calorie restriction and ketogenic diet diminish neuronal excitability in rat dentate gyrus in vivo. Epilepsia. 2003 Jun; 44(6):752-60. Bough KJ, Schwartzkroin PA, Rho JM. PMID: 12790887.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimals
    118. Intravenous immunoglobulin as adjunctive therapy for juvenile spasms. J Child Neurol. 2003 Jun; 18(6):379-82. Bingel U, Pinter JD, Sotero de Menezes M, Rho JM. PMID: 12886970.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    119. Molecular biology and ontogeny of gamma-aminobutyric acid (GABA) receptors in the mammalian central nervous system. J Child Neurol. 2003 Jan; 18(1):39-48; discussion 49. Simeone TA, Donevan SD, Rho JM. PMID: 12661937.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    120. Clinical and electrographic features of epileptic spasms persisting beyond the second year of life. Epilepsia. 2002 Jun; 43(6):623-30. de Menezes MA, Rho JM. PMID: 12060022.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    121. Acetoacetate, acetone, and dibenzylamine (a contaminant in l-(+)-beta-hydroxybutyrate) exhibit direct anticonvulsant actions in vivo. Epilepsia. 2002 Apr; 43(4):358-61. Rho JM, Anderson GD, Donevan SD, White HS. PMID: 11952765.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsPHPublic Health
    122. Ictal EEG patterns in band heterotopia. Epilepsia. 2002 Apr; 43(4):403-7. Grant AC, Rho JM. PMID: 11952771.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    123. Age-dependent differences in flurothyl-induced c-fos and c-jun mRNA expression in the mouse brain. Dev Neurosci. 2002; 24(4):294-9. Storey TW, Rho JM, White SS, Sankar R, Szot P. PMID: 12457067.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
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