-
Human retinal ganglion cell neurons generated by synchronous BMP inhibition and transcription factor mediated reprogramming. NPJ Regen Med. 2023 Sep 29; 8(1):55.
Agarwal D, Dash N, Mazo KW, Chopra M, Avila MP, Patel A, Wong RM, Jia C, Do H, Cheng J, Chiang C, Jurlina SL, Roshan M, Perry MW, Rho JM, Broyer R, Lee CD, Weinreb RN, Gavrilovici C, Oesch NW, Welsbie DS, Wahlin KJ. PMID: 37773257; PMCID: PMC10541876.
View in:
PubMed Mentions:
-
Postictal hypoxia involves reactive oxygen species and is ameliorated by chronic mitochondrial uncoupling. Neuropharmacology. 2023 11 01; 238:109653.
Villa BR, George AG, Shutt TE, Sullivan PG, Rho JM, Teskey GC. PMID: 37422182.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Intermittent vs continuous ketogenic diet: Impact on seizures, gut microbiota, and mitochondrial metabolism. Epilepsia. 2023 08; 64(8):e177-e183.
Shearer J, Scantlebury MH, Rho JM, Tompkins TA, Mu C. PMID: 37335622.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
kcna1a mutant zebrafish model episodic ataxia type 1 (EA1) with epilepsy and show response to first-line therapy carbamazepine. Epilepsia. 2023 08; 64(8):2186-2199.
Dogra D, Meza-Santoscoy PL, Gavrilovici C, Rehak R, de la Hoz CLR, Ibhazehiebo K, Rho JM, Kurrasch DM. PMID: 37209379.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
-
Proposed anti-seizure medication combinations with rufinamide in the treatment of Lennox-Gastaut syndrome: Narrative review and expert opinion. Seizure. 2023 Aug; 110:42-57.
Sankar R, Chez M, Pina-Garza JE, Dixon-Salazar T, Flamini JR, Hyslop A, McGoldrick P, Millichap JJ, Resnick T, Rho JM, Wolf S. PMID: 37321047.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
A clinically relevant selective ERK-pathway inhibitor reverses core deficits in a mouse model of autism. EBioMedicine. 2023 May; 91:104565.
Murari K, Abushaibah A, Rho JM, Turner RW, Cheng N. PMID: 37088035; PMCID: PMC10149189.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Sudden unexpected death in epilepsy is prevented by blocking postictal hypoxia. Neuropharmacology. 2023 06 15; 231:109513.
George AG, Farrell JS, Colangeli R, Wall AK, Gom RC, Kesler MT, Rodriguez de la Hoz C, Villa BR, Perera T, Rho JM, Kurrasch D, Teskey GC. PMID: 36948357.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
-
Cannabidiol Impairs Brain Mitochondrial Metabolism and Neuronal Integrity. Cannabis Cannabinoid Res. 2023 04; 8(2):283-298.
Drummond-Main CD, Ahn Y, Kesler M, Gavrilovici C, Kim DY, Kiroski I, Baglot SL, Chen A, Sharkey KA, Hill MN, Teskey GC, Rho JM. PMID: 36108318; PMCID: PMC10061329.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Genotype-phenotype correlations in SCN8A-related disorders reveal prognostic and therapeutic implications. Brain. 2022 09 14; 145(9):2991-3009.
Johannesen KM, Liu Y, Koko M, Gjerulfsen CE, Sonnenberg L, Schubert J, Fenger CD, Eltokhi A, Rannap M, Koch NA, Lauxmann S, Krüger J, Kegele J, Canafoglia L, Franceschetti S, Mayer T, Rebstock J, Zacher P, Ruf S, Alber M, Sterbova K, Lassuthová P, Vlckova M, Lemke JR, Platzer K, Krey I, Heine C, Wieczorek D, Kroell-Seger J, Lund C, Klein KM, Au PYB, Rho JM, Ho AW, Masnada S, Veggiotti P, Giordano L, Accorsi P, Hoei-Hansen CE, Striano P, Zara F, Verhelst H, Verhoeven JS, Braakman HMH, van der Zwaag B, Harder AVE, Brilstra E, Pendziwiat M, Lebon S, Vaccarezza M, Le NM, Christensen J, Grønborg S, Scherer SW, Howe J, Fazeli W, Howell KB, Leventer R, Stutterd C, Walsh S, Gerard M, Gerard B, Matricardi S, Bonardi CM, Sartori S, Berger A, Hoffman-Zacharska D, Mastrangelo M, Darra F, Vøllo A, Motazacker MM, Lakeman P, Nizon M, Betzler C, Altuzarra C, Caume R, Roubertie A, Gélisse P, Marini C, Guerrini R, Bilan F, Tibussek D, Koch-Hogrebe M, Perry MS, Ichikawa S, Dadali E, Sharkov A, Mishina I, Abramov M, Kanivets I, Korostelev S, Kutsev S, Wain KE, Eisenhauer N, Wagner M, Savatt JM, Müller-Schlüter K, Bassan H, Borovikov A, Nassogne MC, Destrée A, Schoonjans AS, Meuwissen M, Buzatu M, Jansen A, Scalais E, Srivastava S, Tan WH, Olson HE, Loddenkemper T, Poduri A, Helbig KL, Helbig I, Fitzgerald MP, Goldberg EM, Roser T, Borggraefe I, Brünger T, May P, Lal D, Lederer D, Rubboli G, Heyne HO, Lesca G, Hedrich UBS, Benda J, Gardella E, Lerche H, Møller RS. PMID: 34431999; PMCID: PMC10147326.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
Targeted gut microbiota manipulation attenuates seizures in a model of infantile spasms syndrome. JCI Insight. 2022 06 22; 7(12).
Mu C, Nikpoor N, Tompkins TA, Choudhary A, Wang M, Marks WN, Rho JM, Scantlebury MH, Shearer J. PMID: 35730569; PMCID: PMC9309045.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
Circadian Responses to Light in the BTBR Mouse. J Biol Rhythms. 2022 Oct; 37(5):498-515.
Vijaya Shankara J, Horsley KG, Cheng N, Rho JM, Antle MC. PMID: 35722987; PMCID: PMC9452857.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Selective Probiotic Treatment Positively Modulates the Microbiota-Gut-Brain Axis in the BTBR Mouse Model of Autism. Brain Sci. 2022 Jun 14; 12(6).
Pochakom A, Mu C, Rho JM, Tompkins TA, Mayengbam S, Shearer J. PMID: 35741667; PMCID: PMC9220969.
View in:
PubMed Mentions:
8
-
Addition of Prebiotics to the Ketogenic Diet Improves Metabolic Profile but Does Not Affect Seizures in a Rodent Model of Infantile Spasms Syndrome. Nutrients. 2022 May 26; 14(11).
Mu C, Pochakom A, Reimer RA, Choudhary A, Wang M, Rho JM, Scantlebury MH, Shearer J. PMID: 35684010; PMCID: PMC9182787.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
Gut-based manipulations spur hippocampal mitochondrial bioenergetics in a model of pediatric epilepsy. Biochim Biophys Acta Mol Basis Dis. 2022 09 01; 1868(9):166446.
Mu C, Tompkins TA, Rho JM, Scantlebury MH, Shearer J. PMID: 35589071.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
-
The metabolic basis of epilepsy. Nat Rev Neurol. 2022 06; 18(6):333-347.
Rho JM, Boison D. PMID: 35361967; PMCID: PMC10259193.
View in:
PubMed Mentions:
46 Fields:
Translation:
Humans
-
Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy. EBioMedicine. 2022 Feb; 76:103838.
Mu C, Nikpoor N, Tompkins TA, Rho JM, Scantlebury MH, Shearer J. PMID: 35148983; PMCID: PMC8882998.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
-
Seizure modulation by the gut microbiota and tryptophan-kynurenine metabolism in an animal model of infantile spasms. EBioMedicine. 2022 Feb; 76:103833.
Mu C, Choudhary A, Mayengbam S, Barrett KT, Rho JM, Shearer J, Scantlebury MH. PMID: 35090836; PMCID: PMC8883001.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
-
Abnormal oxidative metabolism in the cuprizone mouse model of demyelination: An in vivo NIRS-MRI study. Neuroimage. 2022 04 15; 250:118935.
Hashem M, Shafqat Q, Wu Y, Rho JM, Dunn JF. PMID: 35091079.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Pharmacokinetics and central accumulation of delta-9-tetrahydrocannabinol (THC) and its bioactive metabolites are influenced by route of administration and sex in rats. Sci Rep. 2021 12 14; 11(1):23990.
Baglot SL, Hume C, Petrie GN, Aukema RJ, Lightfoot SHM, Grace LM, Zhou R, Parker L, Rho JM, Borgland SL, McLaughlin RJ, Brechenmacher L, Hill MN. PMID: 34907248; PMCID: PMC8671514.
View in:
PubMed Mentions:
26 Fields:
Translation:
Animals
-
Three dimensional microelectrodes enable high signal and spatial resolution for neural seizure recordings in brain slices and freely behaving animals. Sci Rep. 2021 11 09; 11(1):21952.
Wijdenes P, Haider K, Gavrilovici C, Gunning B, Wolff MD, Lijnse T, Armstrong R, Teskey GC, Rho JM, Dalton C, Syed NI. PMID: 34754055; PMCID: PMC8578611.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
A ketogenic diet affects brain volume and metabolome in juvenile mice. Neuroimage. 2021 12 01; 244:118542.
Mayengbam S, Ellegood J, Kesler M, Reimer RA, Shearer J, Murari K, Rho JM, Lerch JP, Cheng N. PMID: 34530134.
View in:
PubMed Mentions:
6 Fields:
Translation:
Animals
-
Prebiotic, Probiotic, and Synbiotic Consumption Alter Behavioral Variables and Intestinal Permeability and Microbiota in BTBR Mice. Microorganisms. 2021 Aug 29; 9(9).
Nettleton JE, Klancic T, Schick A, Choo AC, Cheng N, Shearer J, Borgland SL, Rho JM, Reimer RA. PMID: 34576728; PMCID: PMC8469248.
View in:
PubMed Mentions:
12
-
The link between brain acidosis, breathing and seizures: a novel mechanism of action for the ketogenic diet in a model of infantile spasms. Brain Commun. 2021; 3(4):fcab189.
Choudhary A, Mu C, Barrett KT, Charkhand B, Williams-Dyjur C, Marks WN, Shearer J, Rho JM, Scantlebury MH. PMID: 34734183; PMCID: PMC8557655.
View in:
PubMed Mentions:
10
-
Metabolism-based therapies for epilepsy: new directions for future cures. Ann Clin Transl Neurol. 2021 08; 8(8):1730-1737.
Cervenka M, Pascual JM, Rho JM, Thiele E, Yellen G, Whittemore V, Hartman AL. PMID: 34247456; PMCID: PMC8351378.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Ketogenic diet-mediated seizure reduction preserves CA1 cell numbers in epileptic Kcna1-null mice: An unbiased stereological assessment. Epilepsia. 2021 08; 62(8):e123-e128.
Simeone KA, Wilke JC, Matthews SA, Simeone TA, Rho JM. PMID: 34231878.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
The ketogenic diet raises brain oxygen levels, attenuates postictal hypoxia, and protects against learning impairments. Neurobiol Dis. 2021 07; 154:105335.
Gom RC, Bhatt D, Villa BR, George AG, Lohman AW, Mychasiuk R, Rho JM, Teskey GC. PMID: 33741453.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Creation and implementation of an electronic health record note for quality improvement in pediatric epilepsy: Practical considerations and lessons learned. Epilepsia Open. 2021 06; 6(2):345-358.
Buchhalter JR, Scantlebury MH, D'Alfonso S, Pablo Appendino J, Bello Espinosa L, Brooks BL, Claassen C, Corbeil J, Czank D, Dean S, Ho AW, Jacobs J, Mackay M, McMahon J, Mineyko A, Rho JM, Roberts T, Rothenmund S, Ruta G, Sawchuk T, Simms BA, Smyth K, Still T, Thornton N. PMID: 34033240; PMCID: PMC8166802.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Behavioral Deficits in Mice with Postnatal Disruption of Ndel1 in Forebrain Excitatory Neurons: Implications for Epilepsy and Neuropsychiatric Disorders. Cereb Cortex Commun. 2021; 2(1):tgaa096.
Gavrilovici C, Jiang Y, Kiroski I, Sterley TL, Vandal M, Bains J, Park SK, Rho JM, Teskey GC, Nguyen MD. PMID: 33615226; PMCID: PMC7876307.
View in:
PubMed Mentions:
5
-
Metabolic epilepsies amenable to ketogenic therapies: Indications, contraindications, and underlying mechanisms. J Inherit Metab Dis. 2021 01; 44(1):42-53.
Gavrilovici C, Rho JM. PMID: 32654164.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
-
Reelin Improves Cognition and Extends the Lifespan of Mutant Ndel1 Mice with Postnatal CA1 Hippocampus Deterioration. Cereb Cortex. 2020 07 30; 30(9):4964-4978.
Kiroski I, Jiang Y, Gavrilovici C, Gao F, Lee S, Scantlebury MH, Vandal M, Park SK, Tsai LH, Teskey GC, Rho JM, Nguyen MD. PMID: 32328622; PMCID: PMC7391417.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Atypical visual processing in a mouse model of autism. Sci Rep. 2020 07 24; 10(1):12390.
Cheng N, Pagtalunan E, Abushaibah A, Naidu J, Stell WK, Rho JM, Sauvé Y. PMID: 32709898; PMCID: PMC7381655.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Postnatal Role of the Cytoskeleton in Adult Epileptogenesis. Cereb Cortex Commun. 2020; 1(1):tgaa024.
Gavrilovici C, Jiang Y, Kiroski I, Teskey GC, Rho JM, Nguyen MD. PMID: 32864616; PMCID: PMC7446231.
View in:
PubMed Mentions:
5
-
FMRP(1-297)-tat restores ion channel and synaptic function in a model of Fragile X syndrome. Nat Commun. 2020 06 02; 11(1):2755.
Zhan X, Asmara H, Cheng N, Sahu G, Sanchez E, Zhang FX, Zamponi GW, Rho JM, Turner RW. PMID: 32488011; PMCID: PMC7265297.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Aberrant Mitochondrial Morphology and Function in the BTBR Mouse Model of Autism Is Improved by Two Weeks of Ketogenic Diet. Int J Mol Sci. 2020 May 05; 21(9).
Ahn Y, Sabouny R, Villa BR, Yee NC, Mychasiuk R, Uddin GM, Rho JM, Shutt TE. PMID: 32380723; PMCID: PMC7246481.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
Metabolism-based drug discovery in zebrafish: An emerging strategy to uncover new anti-seizure therapies. Neuropharmacology. 2020 05 01; 167:107988.
Ibhazehiebo K, Rho JM, Kurrasch DM. PMID: 32070912.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Metabolic Framework for the Improvement of Autism Spectrum Disorders by a Modified Ketogenic Diet: A Pilot Study. J Proteome Res. 2020 01 03; 19(1):382-390.
Mu C, Corley MJ, Lee RWY, Wong M, Pang A, Arakaki G, Miyamoto R, Rho JM, Mickiewicz B, Dowlatabadi R, Vogel HJ, Korchemagin Y, Shearer J. PMID: 31696714.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCTClinical Trials
-
Position Statement on the Use of Medical Cannabis for the Treatment of Epilepsy in Canada. Can J Neurol Sci. 2019 11; 46(6):645-652.
Appendino JP, Boelman C, Brna PM, Burneo JG, Claassen CS, Connolly MB, De Guzman MVT, Federico P, Floyd D, Huntsman RJ, Javidan M, Jette N, Jurasek LL, Keezer MR, Lau JC, McCoy B, McLachlan RS, Ng MC, Nguyen DK, Reid AY, Rho JM, Snead OC, Téllez-Zenteno JF, Wang L, Zak MM. PMID: 31466531.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives. Front Neurosci. 2019; 13:1041.
Poff AM, Rho JM, D'Agostino DP. PMID: 31680801; PMCID: PMC6803688.
View in:
PubMed Mentions:
23
-
Precocious myelination in a mouse model of autism. Transl Psychiatry. 2019 10 07; 9(1):251.
Khanbabaei M, Hughes E, Ellegood J, Qiu LR, Yip R, Dobry J, Murari K, Lerch JP, Rho JM, Cheng N. PMID: 31591392; PMCID: PMC6779742.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Epigenetics and epilepsy prevention: The therapeutic potential of adenosine and metabolic therapies. Neuropharmacology. 2020 05 01; 167:107741.
Boison D, Rho JM. PMID: 31419398; PMCID: PMC7220211.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
-
Single-center experience with Beta-propeller protein-associated neurodegeneration (BPAN); expanding the phenotypic spectrum. Mol Genet Metab Rep. 2019 Sep; 20:100483.
Chard M, Appendino JP, Bello-Espinosa LE, Curtis C, Rho JM, Wei XC, Al-Hertani W. PMID: 31293896; PMCID: PMC6595096.
View in:
PubMed Mentions:
6
-
Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosis. J Clin Invest. 2019 05 21; 129(8):3277-3292.
Kaushik DK, Bhattacharya A, Mirzaei R, Rawji KS, Ahn Y, Rho JM, Yong VW. PMID: 31112527; PMCID: PMC6668690.
View in:
PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
-
Highlights From the Annual Meeting of the American Epilepsy Society 2018. Epilepsy Curr. 2019 May-Jun; 19(3):152-158.
Jobst BC, Ben-Menachem E, Chapman KE, Fu A, Goldman A, Hirsch LJ, Jehi LE, Kossoff EH, Plueger M, Rho JM, Schevon CA, Shinnar S, Sperling MR, Simeone TA, Wagner JL, Lado F. PMID: 31050308; PMCID: PMC6610384.
View in:
PubMed Mentions:
1
-
2-Deoxyglucose and Beta-Hydroxybutyrate: Metabolic Agents for Seizure Control. Front Cell Neurosci. 2019; 13:172.
Rho JM, Shao LR, Stafstrom CE. PMID: 31114484; PMCID: PMC6503754.
View in:
PubMed Mentions:
19
-
Brief history of anti-seizure drug development. Epilepsia Open. 2018 Dec; 3(Suppl Suppl 2):114-119.
Rho JM, White HS. PMID: 30564769; PMCID: PMC6293064.
View in:
PubMed Mentions:
33 Fields:
-
Glycolytic inhibition: A novel approach toward controlling neuronal excitability and seizures. Epilepsia Open. 2018 Dec; 3(Suppl Suppl 2):191-197.
Shao LR, Rho JM, Stafstrom CE. PMID: 30564778; PMCID: PMC6293058.
View in:
PubMed Mentions:
8 Fields:
-
Altered circadian rhythms and oscillation of clock genes and sirtuin 1 in a model of sudden unexpected death in epilepsy. Epilepsia. 2018 08; 59(8):1527-1539.
Wallace E, Wright S, Schoenike B, Roopra A, Rho JM, Maganti RK. PMID: 30009381.
View in:
PubMed Mentions:
16 Fields:
Translation:
Animals
-
Infantile Epileptic Encephalopathy With Multiple Genetic Mutations: How Important are Variants of Undetermined Significance? Semin Pediatr Neurol. 2018 07; 26:33-36.
Almomen M, Rho JM, Scantlebury MH. PMID: 29961513.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Metabolism and epilepsy: Ketogenic diets as a homeostatic link. Brain Res. 2019 01 15; 1703:26-30.
Masino SA, Rho JM. PMID: 29883626; PMCID: PMC6281876.
View in:
PubMed Mentions:
23 Fields:
Translation:
Humans
-
Comorbid epilepsy in autism spectrum disorder: Implications of postnatal inflammation for brain excitability. Epilepsia. 2018 07; 59(7):1316-1326.
Lewis ML, Kesler M, Candy SA, Rho JM, Pittman QJ. PMID: 29858515.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
-
Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group. Epilepsia Open. 2018 Jun; 3(2):175-192.
Kossoff EH, Zupec-Kania BA, Auvin S, Ballaban-Gil KR, Christina Bergqvist AG, Blackford R, Buchhalter JR, Caraballo RH, Cross JH, Dahlin MG, Donner EJ, Guzel O, Jehle RS, Klepper J, Kang HC, Lambrechts DA, Liu YMC, Nathan JK, Nordli DR, Pfeifer HH, Rho JM, Scheffer IE, Sharma S, Stafstrom CE, Thiele EA, Turner Z, Vaccarezza MM, van der Louw EJTM, Veggiotti P, Wheless JW, Wirrell EC, Charlie Foundation, Matthew's Friends, Practice Committee of the Child Neurology Society. PMID: 29881797; PMCID: PMC5983110.
View in:
PubMed Mentions:
195 Fields:
-
Electrophysiological characterization of a mitochondrial inner membrane chloride channel in rat brain. FEBS Lett. 2018 05; 592(9):1545-1553.
Drummond-Main CD, Rho JM. PMID: 29578588.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
A novel metabolism-based phenotypic drug discovery platform in zebrafish uncovers HDACs 1 and 3 as a potential combined anti-seizure drug target. Brain. 2018 03 01; 141(3):744-761.
Ibhazehiebo K, Gavrilovici C, de la Hoz CL, Ma SC, Rehak R, Kaushik G, Meza Santoscoy PL, Scott L, Nath N, Kim DY, Rho JM, Kurrasch DM. PMID: 29373639; PMCID: PMC5837409.
View in:
PubMed Mentions:
32 Fields:
Translation:
Animals
-
ER-stress mobilization of death-associated protein kinase-1-dependent xenophagy counteracts mitochondria stress-induced epithelial barrier dysfunction. J Biol Chem. 2018 03 02; 293(9):3073-3087.
Lopes F, Keita ÅV, Saxena A, Reyes JL, Mancini NL, Al Rajabi A, Wang A, Baggio CH, Dicay M, van Dalen R, Ahn Y, Carneiro MBH, Peters NC, Rho JM, MacNaughton WK, Girardin SE, Jijon H, Philpott DJ, Söderholm JD, McKay DM. PMID: 29317503; PMCID: PMC5836131.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
-
Do ketone bodies mediate the anti-seizure effects of the ketogenic diet? Neuropharmacology. 2018 05 01; 133:233-241.
Simeone TA, Simeone KA, Stafstrom CE, Rho JM. PMID: 29325899; PMCID: PMC5858992.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansAnimals
-
Ketogenic diet-induced extension of longevity in epileptic Kcna1-null mice is influenced by gender and age at treatment onset. Epilepsy Res. 2018 02; 140:53-55.
Chun KC, Ma SC, Oh H, Rho JM, Kim DY. PMID: 29245026; PMCID: PMC5826793.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Clinical studies and anti-inflammatory mechanisms of treatments. Epilepsia. 2017 07; 58 Suppl 3:69-82.
French JA, Koepp M, Naegelin Y, Vigevano F, Auvin S, Rho JM, Rosenberg E, Devinsky O, Olofsson PS, Dichter MA. PMID: 28675558; PMCID: PMC5679081.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
-
Dendritic overgrowth and elevated ERK signaling during neonatal development in a mouse model of autism. PLoS One. 2017; 12(6):e0179409.
Cheng N, Alshammari F, Hughes E, Khanbabaei M, Rho JM. PMID: 28609458; PMCID: PMC5469475.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
The relationship between d-beta-hydroxybutyrate blood concentrations and seizure control in children treated with the ketogenic diet for medically intractable epilepsy. Epilepsia Open. 2017 09; 2(3):317-321.
Buchhalter JR, D'Alfonso S, Connolly M, Fung E, Michoulas A, Sinasac D, Singer R, Smith J, Singh N, Rho JM. PMID: 29588960; PMCID: PMC5862113.
View in:
PubMed Mentions:
23 Fields:
-
Ketogenic diet leads to O-GlcNAc modification in the BTBRT+tf/j mouse model of autism. Biochim Biophys Acta Mol Basis Dis. 2017 09; 1863(9):2274-2281.
Newell C, Johnsen VL, Yee NC, Xu WJ, Klein MS, Khan A, Rho JM, Shearer J. PMID: 28502704.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Need for new review of article on ketogenic dietary regimes for cancer patients. Med Oncol. 2017 06; 34(6):108.
Klement RJ, Feinman RD, Gross EC, Champ CE, D'Agostino DP, Fine EJ, Kämmerer U, Poff A, Rho JM, Seyfried TN, Scheck AC. PMID: 28452037.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Ketone Bodies as Anti-Seizure Agents. Neurochem Res. 2017 Jul; 42(7):2011-2018.
Simeone TA, Simeone KA, Rho JM. PMID: 28397070; PMCID: PMC5505793.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansAnimals
-
Abnormal Capillary Vasodynamics Contribute to Ictal Neurodegeneration in Epilepsy. Sci Rep. 2017 02 27; 7:43276.
Leal-Campanario R, Alarcon-Martinez L, Rieiro H, Martinez-Conde S, Alarcon-Martinez T, Zhao X, LaMee J, Popp PJ, Calhoun ME, Arribas JI, Schlegel AA, Stasi LL, Rho JM, Inge L, Otero-Millan J, Treiman DM, Macknik SL. PMID: 28240297; PMCID: PMC5327474.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
-
Adrenocorticotropic hormone protects learning and memory function in epileptic Kcna1-null mice. Neurosci Lett. 2017 04 03; 645:14-18.
Scantlebury MH, Chun KC, Ma SC, Rho JM, Kim DY. PMID: 28249786; PMCID: PMC5774237.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Carisbamate blockade of T-type voltage-gated calcium channels. Epilepsia. 2017 04; 58(4):617-626.
Kim DY, Zhang FX, Nakanishi ST, Mettler T, Cho IH, Ahn Y, Hiess F, Chen L, Sullivan PG, Chen SR, Zamponi GW, Rho JM. PMID: 28230232; PMCID: PMC5386822.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
-
Metabolic Dysfunction Underlying Autism Spectrum Disorder and Potential Treatment Approaches. Front Mol Neurosci. 2017; 10:34.
Cheng N, Rho JM, Masino SA. PMID: 28270747; PMCID: PMC5318388.
View in:
PubMed Mentions:
53
-
Tissue Specific Impacts of a Ketogenic Diet on Mitochondrial Dynamics in the BTBRT+tf/j Mouse. Front Physiol. 2016; 7:654.
Newell C, Shutt TE, Ahn Y, Hittel DS, Khan A, Rho JM, Shearer J. PMID: 28082920; PMCID: PMC5186794.
View in:
PubMed Mentions:
18
-
Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder. Mol Autism. 2016; 7(1):37.
Newell C, Bomhof MR, Reimer RA, Hittel DS, Rho JM, Shearer J. PMID: 27594980; PMCID: PMC5009541.
View in:
PubMed Mentions:
114 Fields:
Translation:
AnimalsCells
-
Disruption of visual circuit formation and refinement in a mouse model of autism. Autism Res. 2017 Feb; 10(2):212-223.
Cheng N, Khanbabaei M, Murari K, Rho JM. PMID: 27529416; PMCID: PMC5324550.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
-
Genetic modifications associated with ketogenic diet treatment in the BTBRT+Tf/J mouse model of autism spectrum disorder. Autism Res. 2017 Mar; 10(3):456-471.
Mychasiuk R, Rho JM. PMID: 27529337.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
-
Ketogenic diet treatment increases longevity in Kcna1-null mice, a model of sudden unexpected death in epilepsy. Epilepsia. 2016 08; 57(8):e178-82.
Simeone KA, Matthews SA, Rho JM, Simeone TA. PMID: 27346881; PMCID: PMC4972642.
View in:
PubMed Mentions:
39 Fields:
Translation:
Animals
-
Ndel1 and Reelin Maintain Postnatal CA1 Hippocampus Integrity. J Neurosci. 2016 06 15; 36(24):6538-52.
Jiang Y, Gavrilovici C, Chansard M, Liu RH, Kiroski I, Parsons K, Park SK, Teskey GC, Rho JM, Nguyen MD. PMID: 27307241; PMCID: PMC6601920.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Mechanisms of Action of Antiseizure Drugs and the Ketogenic Diet. Cold Spring Harb Perspect Med. 2016 05 02; 6(5).
Rogawski MA, Löscher W, Rho JM. PMID: 26801895; PMCID: PMC4852797.
View in:
PubMed Mentions:
98 Fields:
Translation:
HumansAnimals
-
Metabolomic Modeling To Monitor Host Responsiveness to Gut Microbiota Manipulation in the BTBR(T+tf/j) Mouse. J Proteome Res. 2016 Apr 01; 15(4):1143-50.
Klein MS, Newell C, Bomhof MR, Reimer RA, Hittel DS, Rho JM, Vogel HJ, Shearer J. PMID: 26928523.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Ketogenic diet restores aberrant cortical motor maps and excitation-to-inhibition imbalance in the BTBR mouse model of autism spectrum disorder. Behav Brain Res. 2016 May 01; 304:67-70.
Smith J, Rho JM, Teskey GC. PMID: 26876011.
View in:
PubMed Mentions:
17 Fields:
Translation:
Animals
-
Teaching NeuroImages: MRI findings in X-linked adrenoleukodystrophy. Neurology. 2015 Oct 27; 85(17):e132-3.
Myers KA, Rho JM, Wei XC. PMID: 26503591; PMCID: PMC4631067.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
How does the ketogenic diet induce anti-seizure effects? Neurosci Lett. 2017 01 10; 637:4-10.
Rho JM. PMID: 26222258.
View in:
PubMed Mentions:
80 Fields:
Translation:
HumansAnimals
-
Inhibition of Lactate Dehydrogenase to Treat Epilepsy. N Engl J Med. 2015 Jul 09; 373(2):187-9.
Rho JM. PMID: 26154793.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimals
-
"Tinkle Tinkle Little Girl, How We Wonder Why You Can't": An Unusual AIDP-like Syndrome in a Toddler. Can J Neurol Sci. 2015 Jul; 42(4):274-7.
Rajapakse T, Hinnell CJ, Wei XC, Mah JK, Rho JM. PMID: 25990009.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Differential effects of duration of sleep fragmentation on spatial learning and synaptic plasticity in pubertal mice. Brain Res. 2015 Jul 30; 1615:116-128.
Wallace E, Kim DY, Kim KM, Chen S, Blair Braden B, Williams J, Jasso K, Garcia A, Rho JM, Bimonte-Nelson H, Maganti R. PMID: 25957790.
View in:
PubMed Mentions:
16 Fields:
Translation:
Animals
-
Ketone bodies mediate antiseizure effects through mitochondrial permeability transition. Ann Neurol. 2015 Jul; 78(1):77-87.
Kim DY, Simeone KA, Simeone TA, Pandya JD, Wilke JC, Ahn Y, Geddes JW, Sullivan PG, Rho JM. PMID: 25899847; PMCID: PMC4480159.
View in:
PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
-
Stoichiometric expression of mtHsp40 and mtHsp70 modulates mitochondrial morphology and cristae structure via Opa1L cleavage. Mol Biol Cell. 2015 Jun 15; 26(12):2156-67.
Lee B, Ahn Y, Kang SM, Park Y, Jeon YJ, Rho JM, Kim SW. PMID: 25904328; PMCID: PMC4462935.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
Ketones prevent oxidative impairment of hippocampal synaptic integrity through KATP channels. PLoS One. 2015; 10(4):e0119316.
Kim DY, Abdelwahab MG, Lee SH, O'Neill D, Thompson RJ, Duff HJ, Sullivan PG, Rho JM. PMID: 25848768; PMCID: PMC4388385.
View in:
PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
-
Efficacy of intravenous immunoglobulin in a cohort of children with drug-resistant epilepsy. Pediatr Neurol. 2015 May; 52(5):509-16.
Bello-Espinosa LE, Rajapakse T, Rho JM, Buchhalter J. PMID: 25882078.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid. Acta Neuropathol Commun. 2015 Jan 20; 3:3.
Nicolini C, Ahn Y, Michalski B, Rho JM, Fahnestock M. PMID: 25627160; PMCID: PMC4307681.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
-
The New Ketone Alphabet Soup: BHB, HCA, and HDAC. Epilepsy Curr. 2014 Nov-Dec; 14(6):355-7.
Hartman AL, Rho JM. PMID: 25678874; PMCID: PMC4325597.
View in:
PubMed Mentions:
5
-
The ketogenic diet modifies social and metabolic alterations identified in the prenatal valproic acid model of autism spectrum disorder. Dev Neurosci. 2014; 36(5):371-80.
Ahn Y, Narous M, Tobias R, Rho JM, Mychasiuk R. PMID: 25011527.
View in:
PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
-
Inchworming: a novel motor stereotypy in the BTBR T+ Itpr3tf/J mouse model of autism. J Vis Exp. 2014 Jul 05; (89).
Smith JD, Rho JM, Masino SA, Mychasiuk R. PMID: 25046063; PMCID: PMC4212568.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels. Mol Brain. 2014 May 31; 7:42.
Stotz SC, Scott LO, Drummond-Main C, Avchalumov Y, Girotto F, Davidsen J, Gómez-Gárcia MR, Rho JM, Pavlov EV, Colicos MA. PMID: 24886461; PMCID: PMC4061113.
View in:
PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
-
Ketogenic diets, mitochondria, and neurological diseases. J Lipid Res. 2014 Nov; 55(11):2211-28.
Gano LB, Patel M, Rho JM. PMID: 24847102; PMCID: PMC4617125.
View in:
PubMed Mentions:
109 Fields:
Translation:
HumansAnimalsCells
-
How is homeostatic plasticity important in epilepsy? Adv Exp Med Biol. 2014; 813:123-31.
Swann JW, Rho JM. PMID: 25012372.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Ketogenic diet improves core symptoms of autism in BTBR mice. PLoS One. 2013; 8(6):e65021.
Ruskin DN, Svedova J, Cote JL, Sandau U, Rho JM, Kawamura M, Boison D, Masino SA. PMID: 23755170; PMCID: PMC3673987.
View in:
PubMed Mentions:
79 Fields:
Translation:
HumansAnimals
-
Loss of the Kv1.1 potassium channel promotes pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices. Neurobiol Dis. 2013 Jun; 54:68-81.
Simeone TA, Simeone KA, Samson KK, Kim DY, Rho JM. PMID: 23466697; PMCID: PMC3648846.
View in:
PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
-
Unilateral foot drop as an initial presentation of a brain tumor in a child. J Child Neurol. 2014 Jul; 29(7):955-8.
Goia E, Hamilton L, Chan J, Wei XC, Mah JK, Rho JM. PMID: 23456535.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
High dose folic acid supplementation of rats alters synaptic transmission and seizure susceptibility in offspring. Sci Rep. 2013; 3:1465.
Girotto F, Scott L, Avchalumov Y, Harris J, Iannattone S, Drummond-Main C, Tobias R, Bello-Espinosa L, Rho JM, Davidsen J, Teskey GC, Colicos MA. PMID: 23492951; PMCID: PMC3598003.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
Sweets Are BAD for Seizures. Epilepsy Curr. 2012 Nov; 12(6):218-9.
Patel M, Rho JM. PMID: 23447715; PMCID: PMC3577124.
View in:
PubMed Mentions:
1
-
Finding a better drug for epilepsy: antiepileptogenesis targets. Epilepsia. 2012 Nov; 53(11):1868-76.
Kobow K, Auvin S, Jensen F, Löscher W, Mody I, Potschka H, Prince D, Sierra A, Simonato M, Pitkänen A, Nehlig A, Rho JM. PMID: 23061663; PMCID: PMC5011430.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimals
-
Inflammation-mediated memory dysfunction and effects of a ketogenic diet in a murine model of multiple sclerosis. PLoS One. 2012; 7(5):e35476.
Kim DY, Hao J, Liu R, Turner G, Shi FD, Rho JM. PMID: 22567104; PMCID: PMC3342287.
View in:
PubMed Mentions:
114 Fields:
Translation:
Animals
-
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma. PLoS One. 2012; 7(5):e36197.
Abdelwahab MG, Fenton KE, Preul MC, Rho JM, Lynch A, Stafford P, Scheck AC. PMID: 22563484; PMCID: PMC3341352.
View in:
PubMed Mentions:
132 Fields:
Translation:
HumansAnimals
-
The ketogenic diet as a treatment paradigm for diverse neurological disorders. Front Pharmacol. 2012; 3:59.
Stafstrom CE, Rho JM. PMID: 22509165; PMCID: PMC3321471.
View in:
PubMed Mentions:
184
-
Adenosine: a fundamental factor formed from Fatty feasts for fighting fits? Epilepsy Curr. 2012 Jan; 12(1):19-21.
Rho JM. PMID: 22368522; PMCID: PMC3280472.
View in:
PubMed Mentions:
-
The ketogenic diet: what has science taught us? Epilepsy Res. 2012 Jul; 100(3):210-7.
Rho JM, Stafstrom CE. PMID: 21856126.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
-
Ketogenic diet in the treatment of seizures associated with hypothalamic hamartomas. Epilepsy Res. 2011 May; 94(3):218-21.
Chapman KE, Kim DY, Rho JM, Ng YT, Kerrigan JF. PMID: 21377333; PMCID: PMC3161155.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Pediatric stroke. Childs Nerv Syst. 2011 Sep; 27(9):1375-90.
Cárdenas JF, Rho JM, Kirton A. PMID: 21336993.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
L-Type calcium channel blockade reduces network activity in human epileptic hypothalamic hamartoma tissue. Epilepsia. 2011 Mar; 52(3):531-40.
Simeone KA, Sabesan S, Kim DY, Kerrigan JF, Rho JM, Simeone TA. PMID: 21269296; PMCID: PMC3071288.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Pediatric neuropharmacotherapeutics. Introduction. Semin Pediatr Neurol. 2010 Dec; 17(4):207.
Pinter JD, Rho JM. PMID: 21183125.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
How does altered metabolism lead to seizure control? Partially filling the knowledge gap. Epilepsy Curr. 2010 Nov; 10(6):159-61.
Rho JM. PMID: 21157545; PMCID: PMC3001026.
View in:
PubMed Mentions:
2
-
The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma. Nutr Metab (Lond). 2010 Sep 10; 7:74.
Stafford P, Abdelwahab MG, Kim DY, Preul MC, Rho JM, Scheck AC. PMID: 20831808; PMCID: PMC2949862.
View in:
PubMed Mentions:
98
-
Another Look at Early GABAergic Neurotransmission: Maybe It's Not So Exciting After All! Epilepsy Curr. 2010 Sep; 10(5):128-30.
Rho JM. PMID: 20944825; PMCID: PMC2951694.
View in:
PubMed Mentions:
-
Modeling action potential generation during single and dual electrode stimulation of CA3 axons in hippocampal slice. Comput Biol Med. 2010 May; 40(5):487-97.
Bellinger SC, Rho JM, Steinmetz PN. PMID: 20381025.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Ketones prevent synaptic dysfunction induced by mitochondrial respiratory complex inhibitors. J Neurochem. 2010 Jul; 114(1):130-41.
Kim DY, Vallejo J, Rho JM. PMID: 20374433; PMCID: PMC3532617.
View in:
PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
-
A "happy" toddler presenting with sudden, life-threatening seizures. Semin Pediatr Neurol. 2010 Mar; 17(1):35-8.
Stein D, Chetty M, Rho JM. PMID: 20434691.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Anticonvulsant effects of the selective melatonin receptor agonist ramelteon. Epilepsy Behav. 2009 Sep; 16(1):52-7.
Fenoglio-Simeone K, Mazarati A, Sefidvash-Hockley S, Shin D, Wilke J, Milligan H, Sankar R, Rho JM, Maganti R. PMID: 19682955.
View in:
PubMed Mentions:
16 Fields:
Translation:
Animals
-
Ketogenic diets: an update for child neurologists. J Child Neurol. 2009 Aug; 24(8):979-88.
Kossoff EH, Zupec-Kania BA, Rho JM. PMID: 19535814.
View in:
PubMed Mentions:
55 Fields:
Translation:
Humans
-
Reversible lamotrigine-induced neurobehavioral disturbances in children with epilepsy. J Child Neurol. 2010 Feb; 25(2):182-7.
Cardenas JF, Rho JM, Ng YT. PMID: 19494356.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Ketogenic diet treatment abolishes seizure periodicity and improves diurnal rhythmicity in epileptic Kcna1-null mice. Epilepsia. 2009 Sep; 50(9):2027-34.
Fenoglio-Simeone KA, Wilke JC, Milligan HL, Allen CN, Rho JM, Maganti RK. PMID: 19490051; PMCID: PMC3724531.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansAnimals
-
Ketogenic diets: evidence for short- and long-term efficacy. Neurotherapeutics. 2009 Apr; 6(2):406-14.
Kossoff EH, Rho JM. PMID: 19332337; PMCID: PMC4071763.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansAnimals
-
Arresting a seizure by dropping a little Acid. Epilepsy Curr. 2009 Mar-Apr; 9(2):55-6.
Rho JM. PMID: 19421382; PMCID: PMC2673408.
View in:
PubMed Mentions:
-
Bicarbonate contributes to GABAA receptor-mediated neuronal excitation in surgically resected human hypothalamic hamartomas. Epilepsy Res. 2009 Jan; 83(1):89-93.
Kim DY, Fenoglio KA, Kerrigan JF, Rho JM. PMID: 19022626; PMCID: PMC2692870.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
Oxidative impairment of hippocampal long-term potentiation involves activation of protein phosphatase 2A and is prevented by ketone bodies. J Neurosci Res. 2008 Nov 15; 86(15):3322-30.
Maalouf M, Rho JM. PMID: 18646208; PMCID: PMC2575137.
View in:
PubMed Mentions:
33 Fields:
Translation:
Animals
-
The ketogenic diet in a pill: is this possible? Epilepsia. 2008 Nov; 49 Suppl 8:127-33.
Rho JM, Sankar R. PMID: 19049610; PMCID: PMC2692867.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansAnimals
-
UCP-mediated free fatty acid uncoupling of isolated cortical mitochondria from fasted animals: correlations to dietary modulations. Epilepsia. 2008 Nov; 49 Suppl 8:117-9.
Davis LM, Rho JM, Sullivan PG. PMID: 19049607; PMCID: PMC3262228.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Epilepsia. Ketogenic diet and treatments. Introduction/perspectives. Epilepsia. 2008 Nov; 49 Suppl 8:1-2.
Stafstrom CE, Zupec-Kania B, Rho JM. PMID: 19049573.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies. Brain Res Rev. 2009 Mar; 59(2):293-315.
Maalouf M, Rho JM, Mattson MP. PMID: 18845187; PMCID: PMC2649682.
View in:
PubMed Mentions:
238 Fields:
Translation:
HumansAnimalsCells
-
Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group. Epilepsia. 2009 Feb; 50(2):304-17.
Kossoff EH, Zupec-Kania BA, Amark PE, Ballaban-Gil KR, Christina Bergqvist AG, Blackford R, Buchhalter JR, Caraballo RH, Helen Cross J, Dahlin MG, Donner EJ, Klepper J, Jehle RS, Kim HD, Christiana Liu YM, Nation J, Nordli DR, Pfeifer HH, Rho JM, Stafstrom CE, Thiele EA, Turner Z, Wirrell EC, Wheless JW, Veggiotti P, Vining EP, Charlie Foundation, Practice Committee of the Child Neurology Society, Practice Committee of the Child Neurology Society, International Ketogenic Diet Study Group. PMID: 18823325.
View in:
PubMed Mentions:
123 Fields:
Translation:
Humans
-
GABA(A) receptor-mediated excitation in dissociated neurons from human hypothalamic hamartomas. Exp Neurol. 2008 Oct; 213(2):397-404.
Wu J, DeChon J, Xue F, Li G, Ellsworth K, Gao M, Liu Q, Yang K, Zheng C, He P, Tu J, Kim DY, Rho JM, Rekate H, Kerrigan JF, Chang Y. PMID: 18675803; PMCID: PMC2578824.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Fasting is neuroprotective following traumatic brain injury. J Neurosci Res. 2008 Jun; 86(8):1812-22.
Davis LM, Pauly JR, Readnower RD, Rho JM, Sullivan PG. PMID: 18241053.
View in:
PubMed Mentions:
83 Fields:
Translation:
AnimalsCells
-
Can reducing sugar retard kindling? Epilepsy Curr. 2008 May-Jun; 8(3):83-4.
Rho JM. PMID: 18488064; PMCID: PMC2384159.
View in:
PubMed Mentions:
-
The ketogenic diet and epilepsy. Curr Opin Clin Nutr Metab Care. 2008 Mar; 11(2):113-20.
Kim DY, Rho JM. PMID: 18301085.
View in:
PubMed Mentions:
41 Fields:
Translation:
Humans
-
GABAA receptor-mediated activation of L-type calcium channels induces neuronal excitation in surgically resected human hypothalamic hamartomas. Epilepsia. 2008 May; 49(5):861-71.
Kim DY, Fenoglio KA, Simeone TA, Coons SW, Wu J, Chang Y, Kerrigan JF, Rho JM. PMID: 18076645.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
-
Substantia(ting) ketone body effects on neuronal excitability. Epilepsy Curr. 2007 Sep-Oct; 7(5):142-4.
Rho JM. PMID: 17998978; PMCID: PMC2043136.
View in:
PubMed Mentions:
-
Hypothalamic hamartoma: basic mechanisms of intrinsic epileptogenesis. Semin Pediatr Neurol. 2007 Jun; 14(2):51-9.
Fenoglio KA, Wu J, Kim DY, Simeone TA, Coons SW, Rekate H, Rho JM, Kerrigan JF. PMID: 17544947.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Do seizures affect the developing brain? Lessons from the laboratory. J Child Neurol. 2007 May; 22(5 Suppl):21S-9S.
Sankar R, Rho JM. PMID: 17690084.
View in:
PubMed Mentions:
14 Fields:
Translation:
Animals
-
Electrophysiological properties and subunit composition of GABAA receptors in patients with gelastic seizures and hypothalamic hamartoma. J Neurophysiol. 2007 Jul; 98(1):5-15.
Wu J, Chang Y, Li G, Xue F, DeChon J, Ellsworth K, Liu Q, Yang K, Bahadroani N, Zheng C, Zhang J, Rekate H, Rho JM, Kerrigan JF. PMID: 17428906.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
-
Ketone bodies are protective against oxidative stress in neocortical neurons. J Neurochem. 2007 Jun; 101(5):1316-26.
Kim DY, Davis LM, Sullivan PG, Maalouf M, Simeone TA, van Brederode J, Rho JM. PMID: 17403035.
View in:
PubMed Mentions:
93 Fields:
Translation:
AnimalsCells
-
The ketogenic diet: stoking the powerhouse of the cell. Epilepsy Curr. 2007 Mar-Apr; 7(2):58-60.
Rho JM, Rogawski MA. PMID: 17505556; PMCID: PMC1867088.
View in:
PubMed Mentions:
4
-
Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation. Neuroscience. 2007 Mar 02; 145(1):256-64.
Maalouf M, Sullivan PG, Davis L, Kim DY, Rho JM. PMID: 17240074; PMCID: PMC1865572.
View in:
PubMed Mentions:
213 Fields:
Translation:
AnimalsCells
-
Anticonvulsant mechanisms of the ketogenic diet. Epilepsia. 2007 Jan; 48(1):43-58.
Bough KJ, Rho JM. PMID: 17241207.
View in:
PubMed Mentions:
148 Fields:
Translation:
Humans
-
Impaired motor control in patients with benign focal epilepsy of childhood. J Child Neurol. 2006 Feb; 21(2):157-60.
Maalouf M, Takahashi CD, Reinkensmeyer DJ, Cooper DM, Rho JM. PMID: 16566883.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Electrophysiological properties of human hypothalamic hamartomas. Ann Neurol. 2005 Sep; 58(3):371-82.
Wu J, Xu L, Kim DY, Rho JM, St John PA, Lue LF, Coons S, Ellsworth K, Nowak L, Johnson E, Rekate H, Kerrigan JF. PMID: 16130091.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
-
Single channel properties of hyperpolarization-activated cation currents in acutely dissociated rat hippocampal neurones. J Physiol. 2005 Oct 15; 568(Pt 2):371-80.
Simeone TA, Rho JM, Baram TZ. PMID: 16123099; PMCID: PMC1474727.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Clinical experience with zonisamide monotherapy and adjunctive therapy in children with epilepsy at a tertiary care referral center. J Child Neurol. 2005 Mar; 20(3):212-9.
Kim HL, Aldridge J, Rho JM. PMID: 15832611.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
A cDNA microarray analysis of gene expression profiles in rat hippocampus following a ketogenic diet. Brain Res Mol Brain Res. 2004 Oct 22; 129(1-2):80-7.
Noh HS, Lee HP, Kim DW, Kang SS, Cho GJ, Rho JM, Choi WS. PMID: 15469884.
View in:
PubMed Mentions:
38 Fields:
Translation:
Animals
-
Effects of flunarizine on spontaneous synaptic currents in rat neocortex. Naunyn Schmiedebergs Arch Pharmacol. 2004 Sep; 370(3):176-82.
Golumbek PT, Rho JM, Spain WJ, van Brederode JF. PMID: 15340775.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Lack of long-term histopathologic changes in brain and skeletal muscle of mice treated with a ketogenic diet. J Child Neurol. 2004 Jul; 19(7):555-7.
Rho JM, Sarnat HB, Sullivan PG, Robbins CA, Kim DW. PMID: 15526964.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
Molecular biology and ontogeny of glutamate receptors in the mammalian central nervous system. J Child Neurol. 2004 May; 19(5):343-60; discussion 361.
Simeone TA, Sanchez RM, Rho JM. PMID: 15224708.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansAnimals
-
The ketogenic diet increases mitochondrial uncoupling protein levels and activity. Ann Neurol. 2004 Apr; 55(4):576-80.
Sullivan PG, Rippy NA, Dorenbos K, Concepcion RC, Agarwal AK, Rho JM. PMID: 15048898.
View in:
PubMed Mentions:
160 Fields:
Translation:
AnimalsCells
-
Basic science behind the catastrophic epilepsies. Epilepsia. 2004; 45 Suppl 5:5-11.
Rho JM. PMID: 15283705.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Voltage-dependent block of N-methyl-D-aspartate receptors by the novel anticonvulsant dibenzylamine, a bioactive constituent of L-(+)-beta-hydroxybutyrate. Epilepsia. 2003 Oct; 44(10):1274-9.
Donevan SD, White HS, Anderson GD, Rho JM. PMID: 14510820.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Calorie restriction and ketogenic diet diminish neuronal excitability in rat dentate gyrus in vivo. Epilepsia. 2003 Jun; 44(6):752-60.
Bough KJ, Schwartzkroin PA, Rho JM. PMID: 12790887.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansAnimals
-
Intravenous immunoglobulin as adjunctive therapy for juvenile spasms. J Child Neurol. 2003 Jun; 18(6):379-82.
Bingel U, Pinter JD, Sotero de Menezes M, Rho JM. PMID: 12886970.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Molecular biology and ontogeny of gamma-aminobutyric acid (GABA) receptors in the mammalian central nervous system. J Child Neurol. 2003 Jan; 18(1):39-48; discussion 49.
Simeone TA, Donevan SD, Rho JM. PMID: 12661937.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
-
Clinical and electrographic features of epileptic spasms persisting beyond the second year of life. Epilepsia. 2002 Jun; 43(6):623-30.
de Menezes MA, Rho JM. PMID: 12060022.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Ictal EEG patterns in band heterotopia. Epilepsia. 2002 Apr; 43(4):403-7.
Grant AC, Rho JM. PMID: 11952771.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Acetoacetate, acetone, and dibenzylamine (a contaminant in l-(+)-beta-hydroxybutyrate) exhibit direct anticonvulsant actions in vivo. Epilepsia. 2002 Apr; 43(4):358-61.
Rho JM, Anderson GD, Donevan SD, White HS. PMID: 11952765.
View in:
PubMed Mentions:
52 Fields:
Translation:
AnimalsPHPublic Health
-
Age-dependent differences in flurothyl-induced c-fos and c-jun mRNA expression in the mouse brain. Dev Neurosci. 2002; 24(4):294-9.
Storey TW, Rho JM, White SS, Sankar R, Szot P. PMID: 12457067.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
Norepinephrine is required for the anticonvulsant effect of the ketogenic diet. Brain Res Dev Brain Res. 2001 Aug 23; 129(2):211-4.
Szot P, Weinshenker D, Rho JM, Storey TW, Schwartzkroin PA. PMID: 11506865.
View in:
PubMed Mentions:
23 Fields:
Translation:
Animals
-
Molecular ontogeny of major neurotransmitter receptor systems in the mammalian central nervous system: norepinephrine, dopamine, serotonin, acetylcholine, and glycine. J Child Neurol. 2001 Apr; 16(4):271-280; discussion 281.
Rho JM, Storey TW. PMID: 11332462.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Evidence of altered inhibition in layer V pyramidal neurons from neocortex of Kcna1-null mice. Neuroscience. 2001; 103(4):921-9.
van Brederode JF, Rho JM, Cerne R, Tempel BL, Spain WJ. PMID: 11301201.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Lamotrigine-induced tic disorder: report of five pediatric cases. Epilepsia. 2000 Jul; 41(7):862-7.
Sotero de Menezes MA, Rho JM, Murphy P, Cheyette S. PMID: 10897158.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Age-dependent differences in flurothyl seizure sensitivity in mice treated with a ketogenic diet. Epilepsy Res. 1999 Dec; 37(3):233-40.
Rho JM, Kim DW, Robbins CA, Anderson GD, Schwartzkroin PA. PMID: 10584973.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansAnimals
-
Developmental seizure susceptibility of kv1.1 potassium channel knockout mice. Dev Neurosci. 1999 Nov; 21(3-5):320-7.
Rho JM, Szot P, Tempel BL, Schwartzkroin PA. PMID: 10575255.
View in:
PubMed Mentions:
32 Fields:
Translation:
Animals
-
The pharmacologic basis of antiepileptic drug action. Epilepsia. 1999 Nov; 40(11):1471-83.
Rho JM, Sankar R. PMID: 10565572.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
-
N-methyl-D-aspartate receptor channel block by the enantiomeric 6,7-benzomorphans BIII 277 CL and BIII 281 CL. J Pharmacol Exp Ther. 1998 May; 285(2):767-76.
Grauert M, Rho JM, Subramaniam S, Rogawski MA. PMID: 9580625.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
Alternating hemiplegia of childhood: insights into its pathophysiology. J Child Neurol. 1998 Jan; 13(1):39-45.
Rho JM, Chugani HT. PMID: 9477247.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Barbiturate-like actions of the propanediol dicarbamates felbamate and meprobamate. J Pharmacol Exp Ther. 1997 Mar; 280(3):1383-91.
Rho JM, Donevan SD, Rogawski MA. PMID: 9067327.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
Direct activation of GABAA receptors by barbiturates in cultured rat hippocampal neurons. J Physiol. 1996 Dec 01; 497 ( Pt 2):509-22.
Rho JM, Donevan SD, Rogawski MA. PMID: 8961191; PMCID: PMC1161000.
View in:
PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
-
Felbamate block of the N-methyl-D-aspartate receptor. J Pharmacol Exp Ther. 1995 May; 273(2):878-86.
Subramaniam S, Rho JM, Penix L, Donevan SD, Fielding RP, Rogawski MA. PMID: 7752093.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
Mechanism of action of the anticonvulsant felbamate: opposing effects on N-methyl-D-aspartate and gamma-aminobutyric acidA receptors. Ann Neurol. 1994 Feb; 35(2):229-34.
Rho JM, Donevan SD, Rogawski MA. PMID: 8109904.
View in:
PubMed Mentions:
32 Fields:
Translation:
AnimalsCells