Loading...
Sign in to edit your profile (add interests, mentoring, photo, etc.)

    John Smythies

    TitleProject Scientist
    SchoolUniversity of California, San Diego
    DepartmentPsychology
    Address9500 Gilman Drive #0109
    CA La Jolla 92093
    vCardDownload vCard

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Smythies J, de Lantremange Md. The Nature and Function of Digital Information Compression Mechanisms in the Brain and in Digital Television Technology. Front Syst Neurosci. 2016; 10:40. PMID: 27199688; PMCID: PMC4858531.
      2. Edelstein L, Fuxe K, Levin M, Popescu BO, Smythies J. Telocytes in their context with other intercellular communication agents. Semin Cell Dev Biol. 2016 Jul; 55:9-13. PMID: 27013113.
        View in: PubMed
      3. Smythies J. On the function of object cells in the claustrum-key components in information processing in the visual system? Front Cell Neurosci. 2015; 9:443. PMID: 26594152; PMCID: PMC4633478.
      4. Smythies J. On the possible role of protein vibrations in information processing in the brain: three Russian dolls. Front Mol Neurosci. 2015; 8:38. PMID: 26257604; PMCID: PMC4511836.
      5. Smythies J. Intercellular Signaling in Cancer-the SMT and TOFT Hypotheses, Exosomes, Telocytes and Metastases: Is the Messenger in the Message? J Cancer. 2015; 6(7):604-9. PMID: 26078789; PMCID: PMC4466408.
      6. Smythies J. Off the beaten track: the molecular structure of long-term memory: three novel hypotheses-electrical, chemical and anatomical (allosteric). Front Integr Neurosci. 2015; 9:4. PMID: 25688189; PMCID: PMC4310284.
      7. Edelstein L, Smythies J, Noble D. Introduction. Philos Trans R Soc Lond B Biol Sci. 2014 Sep 26; 369(1652). PMID: 25135962; PMCID: PMC4142022.
      8. Edelstein L, Smythies J. The role of epigenetic-related codes in neurocomputation: dynamic hardware in the brain. Philos Trans R Soc Lond B Biol Sci. 2014 Sep 26; 369(1652). PMID: 25135980; PMCID: PMC4142040.
      9. Smythies LE, Smythies J. Microbiota, the immune system, black moods and the brain-melancholia updated. Front Hum Neurosci. 2014; 8:720. PMID: 25309394; PMCID: PMC4163975.
      10. Smythies J, Edelstein L. The desferrioxamine-prochlorperazine coma-clue to the role of dopamine-iron recycling in the synthesis of hydrogen peroxide in the brain. Front Mol Neurosci. 2014; 7:74. PMID: 25136292; PMCID: PMC4120698.
      11. Smythies J, Edelstein L, Ramachandran V. Molecular mechanisms for the inheritance of acquired characteristics-exosomes, microRNA shuttling, fear and stress: Lamarck resurrected? Front Genet. 2014; 5:133. PMID: 24860599; PMCID: PMC4030137.
      12. Edelstein L, Smythies J. The role of telocytes in morphogenetic bioelectrical signaling: once more unto the breach. Front Mol Neurosci. 2014; 7:41. PMID: 24860423; PMCID: PMC4026729.
      13. Smythies LE, Smythies J. Exosomes in the gut. Front Immunol. 2014; 5:104. PMID: 24672525; PMCID: PMC3955839.
      14. Edelstein L, Fuxe K, Smythies J. Life without glutamate: the epigenetic effects of glutamate deletion. Front Mol Neurosci. 2014; 7:14. PMID: 24616661; PMCID: PMC3935490.
      15. Edelstein L, Smythies J. Epigenetic aspects of telocytes/cordocytes: jacks of all trades, masters of most. Front Cell Neurosci. 2014; 8:32. PMID: 24574968; PMCID: PMC3918656.
      16. Smythies J, Edelstein L, Ramachandran V. Hypotheses relating to the function of the claustrum II: does the claustrum use frequency codes? Front Integr Neurosci. 2014; 8:7. PMID: 24523681; PMCID: PMC3905198.
      17. Smythies J, Edelstein L. Telocytes, exosomes, gap junctions and the cytoskeleton: the makings of a primitive nervous system? Front Cell Neurosci. 2014; 7:278. PMID: 24427115; PMCID: PMC3879459.
      18. Edelstein L, Smythies J. Hypotheses concerning how Otx2 makes its incredible journey: a hitchhiker on the road to Rome? Front Mol Neurosci. 2013; 6:55. PMID: 24415998; PMCID: PMC3874477.
      19. Smythies J, Edelstein L. Interactions between the spike code and the epigenetic code during information processing in the brain. Front Mol Neurosci. 2013; 6:17. PMID: 23847467; PMCID: PMC3703540.
      20. Smythies J. Schizophrenia: one coat of many colors. Front Psychiatry. 2013; 4:43. PMID: 23750136; PMCID: PMC3664319.
      21. Smythies J, Edelstein L. Spike dynamic and epigenetic malfunctions in epilepsy: a tale of two codes. Front Neurol. 2013; 4:63. PMID: 23750152; PMCID: PMC3664324.
      22. Smythies J, Edelstein L. Transsynaptic modality codes in the brain: possible involvement of synchronized spike timing, microRNAs, exosomes and epigenetic processes. Front Integr Neurosci. 2012; 6:126. PMID: 23316146; PMCID: PMC3539687.
      23. Smythies J, Edelstein L, Ramachandran V. Hypotheses relating to the function of the claustrum. Front Integr Neurosci. 2012; 6:53. PMID: 22876222; PMCID: PMC3410410.
      24. Smythies J. Does the O'Brien cycle occur in vivo as a key component in H(2)O(2) production and redox signalling? Med Hypotheses. 2011 Feb; 76(2):299-301. PMID: 21109358.
        View in: PubMed
      25. Smythies J. The neural control of mood: the possible role of the adrenergic system in the medulla. Conscious Cogn. 2011 Sep; 20(3):489-93. PMID: 21075648.
        View in: PubMed
      26. Smythies J. Philosophy, perception, and neuroscience. Perception. 2009; 38(5):638-51. PMID: 19662940.
        View in: PubMed
      27. Smythies J. Section I. The cholinergic system. Int Rev Neurobiol. 2005; 64:1-122. PMID: 16096020.
        View in: PubMed
      28. Smythies J. Section II. The dopamine system. Int Rev Neurobiol. 2005; 64:123-72. PMID: 16096021.
        View in: PubMed
      29. Smythies J. Section III. The norepinephrine system. Int Rev Neurobiol. 2005; 64:173-211. PMID: 16096022.
        View in: PubMed
      30. Smythies J. Section IV. The adrenaline system. Int Rev Neurobiol. 2005; 64:213-5. PMID: 16096023.
        View in: PubMed
      31. Smythies J. Section V. Serotonin system. Int Rev Neurobiol. 2005; 64:217-68. PMID: 16096024.
        View in: PubMed
      32. Smythies J. Section VI. Conclusion. Int Rev Neurobiol. 2005; 64:269-71. PMID: 16096025.
        View in: PubMed
      33. Smythies J. How the brain decides what we see. J R Soc Med. 2005 Jan; 98(1):18-20. PMID: 15632230; PMCID: PMC1079232.
      34. Smythies J, Golomb B. Nerve gas antidotes. J R Soc Med. 2004 Jan; 97(1):32. PMID: 14702366; PMCID: PMC1079267.
      35. Smythies J. The adrenochrome hypothesis of schizophrenia revisited. Neurotox Res. 2002 Mar; 4(2):147-50. PMID: 12829415.
        View in: PubMed
      36. Smythies J, De Iuliis A, Zanatta L, Galzigna L. The biochemical basis of Parkinson's disease: the role of catecholamine o-quinones: a review-discussion. Neurotox Res. 2002 Feb; 4(1):77-81. PMID: 12826496.
        View in: PubMed
      37. Siraki AG, Smythies J, O'Brien PJ. Superoxide radical scavenging and attenuation of hypoxia-reoxygenation injury by neurotransmitter ferric complexes in isolated rat hepatocytes. Neurosci Lett. 2000 Dec 15; 296(1):37-40. PMID: 11099828.
        View in: PubMed
      38. Smythies J. Insulin coma therapy for schizophrenia. J R Soc Med. 2000 Aug; 93(8):449-50. PMID: 10983517; PMCID: PMC1298097.
      39. Smythies J. Redox aspects of signaling by catecholamines and their metabolites. Antioxid Redox Signal. 2000; 2(3):575-83. PMID: 11229369.
        View in: PubMed
      40. Smythies J. The neurotoxicity of glutamate, dopamine, iron and reactive oxygen species: functional interrelationships in health and disease: a review-discussion. Neurotox Res. 1999 Sep; 1(1):27-39. PMID: 12835112.
        View in: PubMed
      41. Smythies J. Consciousness: some basic issues--A neurophilosophical perspective. Conscious Cogn. 1999 Jun; 8(2):164-72. PMID: 10447999.
        View in: PubMed
      42. Smythies J. Redox mechanisms at the glutamate synapse and their significance: a review. Eur J Pharmacol. 1999 Apr 01; 370(1):1-7. PMID: 10323273.
        View in: PubMed
      43. Smythies J. The neurochemical basis of learning and neurocomputation: the redox theory. Behav Brain Res. 1999 Feb 15; 99(1):1-6. PMID: 10512566.
        View in: PubMed
      44. Smythies J, Galzigna L. The oxidative metabolism of catecholamines in the brain: a review. Biochim Biophys Acta. 1998 Apr 10; 1380(2):159-62. PMID: 9565677.
        View in: PubMed
      45. Smythies J. The functional neuroanatomy of awareness: with a focus on the role of various anatomical systems in the control of intermodal attention. Conscious Cogn. 1997 Dec; 6(4):455-81. PMID: 9479480.
        View in: PubMed
      46. Smythies J. The biochemical basis of synaptic plasticity and neurocomputation: a new theory. Proc Biol Sci. 1997 Apr 22; 264(1381):575-9. PMID: 9149426; PMCID: PMC1688402.
      47. Smythies J. Oxidative reactions and schizophrenia: a review-discussion. Schizophr Res. 1997 Apr 11; 24(3):357-64. PMID: 9134597.
        View in: PubMed
      48. Smythies J, Gottfries CG, Regland B. Disturbances of one-carbon metabolism in neuropsychiatric disorders: a review. Biol Psychiatry. 1997 Jan 15; 41(2):230-3. PMID: 9018395.
        View in: PubMed
      49. Smythies J. Endogenous neurotoxins relevant to schizophrenia. J R Soc Med. 1996 Dec; 89(12):679-80. PMID: 9014877; PMCID: PMC1296029.
      50. Smythies J. The role of ascorbate in brain: therapeutic implications. J R Soc Med. 1996 May; 89(5):241. PMID: 8778427; PMCID: PMC1295771.
      51. Smythies J. On the functional of neuromelanin. Proc Biol Sci. 1996 Apr 22; 263(1369):487-9. PMID: 8637929.
        View in: PubMed
      52. Smythies J. A note on the concept of the visual field in neurology, psychology, and visual neuroscience. Perception. 1996; 25(3):369-71. PMID: 8804101.
        View in: PubMed
      53. Tolbert LC, Monti JA, Walter-Ryan W, Alarcon RD, Bahar B, Keriotis JT, Allison JG, Cates A, Antun F, Smythies J. Clinical correlations of one-carbon metabolism abnormalities. Prog Neuropsychopharmacol Biol Psychiatry. 1988; 12(4):491-502. PMID: 3406427.
        View in: PubMed
      54. Smythies J. A brush with tenosynovitis. J R Soc Med. 1987 Feb; 80(2):105-6. PMID: 3560138; PMCID: PMC1290682.
      55. Smythies J, Alarcon RD, Morere D, Monti JA, Steele M, Tolbert LC, Walter-Ryan WG. Abnormalities of one-carbon metabolism in psychiatric disorders: study of methionine adenosyltransferase kinetics and lipid composition of erythrocyte membranes. Biol Psychiatry. 1986 Dec; 21(14):1391-8. PMID: 3790625.
        View in: PubMed
      56. Morere DA, Alarcon RD, Monti JA, Walter-Ryan WG, Bancroft AJ, Smythies J, Tolbert LC. Medication effects on one-carbon metabolism in schizophrenia, mania, and major depression. J Clin Psychopharmacol. 1986 Jun; 6(3):155-61. PMID: 2872235.
        View in: PubMed
      57. Alarcon RD, Tolbert LC, Monti JA, Morere DA, Walter-Ryan WG, Kemp B, Smythies J. One-carbon metabolism disturbances in affective disorders. A preliminary report. J Affect Disord. 1985 Nov; 9(3):297-301. PMID: 2934462.
        View in: PubMed
      58. Smythies J. A further note on the molecular structure of the acetylcholine receptor protein. Med Hypotheses. 1984 Sep; 15(1):93-4. PMID: 6092877.
        View in: PubMed
      59. Smythies J. The role of the one-carbon cycle in neuropsychiatric disease. Biol Psychiatry. 1984 May; 19(5):755-8. PMID: 6329330.
        View in: PubMed
      60. Smythies J. The transmethylation and one-carbon cycle hypotheses of schizophrenia. Psychol Med. 1983 Nov; 13(4):711-4. PMID: 6665089.
        View in: PubMed
      61. Smythies J. A structural study of the full amino acid sequence of subunits alpha, beta, and delta of the acetylcholine receptor protein. Med Hypotheses. 1983 Oct; 12(2):99-102. PMID: 6656684.
        View in: PubMed
      62. Smythies J. A revised model of the molecular structure of the acetylcholine receptor at the neuromuscular junction. Med Hypotheses. 1983 Apr; 10(4):465-8. PMID: 6877123.
        View in: PubMed
      63. Smythies J. Biological markers for the schizophrenic and atypical psychoses. J Nerv Ment Dis. 1982 Dec; 170(12):732-6. PMID: 6754869.
        View in: PubMed
      64. Kelsoe JR, Tolbert LC, Crews EL, Smythies J. Kinetic evidence for decreased methionine adenosyltransferase activity in erythrocytes from schizophrenics. J Neurosci Res. 1982; 8(1):99-103. PMID: 7175980.
        View in: PubMed
      65. Smythies J. An hypothesis of the molecular structure of the dopamine receptor. Med Hypotheses. 1981 Dec; 7(12):1449-56. PMID: 7334949.
        View in: PubMed
      66. Smythies J. On the molecular structure of the ion channel associated with the acetylcholine receptor: a beta-barrel? Med Hypotheses. 1981 Aug; 7(8):1095-8. PMID: 6270518.
        View in: PubMed
      67. Smythies J. A model of the molecular structure of toxin III from Anemonia sulcata. Med Hypotheses. 1981 Jun; 7(6):707-10. PMID: 6116166.
        View in: PubMed
      68. Smythies J. Hypotheses on the molecular mechanism of action of tumor promoters. Med Hypotheses. 1981 Jun; 7(6):711-7. PMID: 7278734.
        View in: PubMed
      69. Smythies J. Possible structures for the nucleosome core of chromatin at the molecular level. Med Hypotheses. 1980 Dec; 6(12):1299-306. PMID: 7219235.
        View in: PubMed
      70. Smythies J. An hypothesis concerning the molecular structure of the nicotinic acetylcholine receptor. Med Hypotheses. 1980 Sep; 6(9):943-50. PMID: 7432253.
        View in: PubMed
      71. Smythies J. Biochemistry and the schizophrenias. South Med J. 1979 Oct; 72(10):1272-6. PMID: 39348.
        View in: PubMed
      72. Smythies J, Morin RD, Brown GB. Identification of dimethyltryptamine and O-methylbufotenin in human cerebrospinal fluid by combined gas chromatography/mass spectrometry. Biol Psychiatry. 1979 Jun; 14(3):549-56. PMID: 289421.
        View in: PubMed
      73. Carl GF, Crews EL, Carmichael SM, Benesh FC, Smythies J. Four enzymes of one-carbon metabolism in blood cells of schizophrenics. Biol Psychiatry. 1978 Dec; 13(6):773-6. PMID: 737266.
        View in: PubMed
      74. Bolme P, Fuxe K, Agnati LF, Bradley R, Smythies J. Cardiovascular effects of morphine and opioid peptides following intracisternal administration in chloralose-anesthetized rats. Eur J Pharmacol. 1978 Apr 01; 48(3):319-24. PMID: 639859.
        View in: PubMed
      75. Robinson CR, Pegram GV, Hyde PR, Beaton JM, Smythies J. The effects of nicotinamide upon sleep in humans. Biol Psychiatry. 1977 Feb; 12(1):139-43. PMID: 189851.
        View in: PubMed
      76. Smythies J. Recent progress in schizophrenia research. Lancet. 1976 Jul 17; 2(7977):136-9. PMID: 59195.
        View in: PubMed
      77. Beaton JM, Smythies J, Bradley RJ. The behavioral effects of L-methionine and related compounds in rats and mice. Biol Psychiatry. 1975 Feb; 10(1):45-52. PMID: 164253.
        View in: PubMed
      78. Smythies J, Bradley RJ, Linton PH. Meeting report: Biochemical aspects of schizophrenia. Alabama, April 1975. Psychoneuroendocrinology. 1975; 1(2):199-201. PMID: 1087034.
        View in: PubMed
      79. Smythies J. The molecular structure of acetycholine and adrenergic receptors: an all-protein model. Int Rev Neurobiol. 1975; 17:131-87. PMID: 237846.
        View in: PubMed
      80. Smythies J. The chemical anatomy of synaptic mechanisms: receptors. Int Rev Neurobiol. 1971; 14:233-331. PMID: 4948650.
        View in: PubMed
      81. Smythies J, Benington F, Morin RD. The mechanism of action of hallucinogenic drugs on a possible serotonin receptor in the brain. Int Rev Neurobiol. 1970; 12:207-33. PMID: 4918144.
        View in: PubMed
      John's Networks
      Concepts
      Derived automatically from this person's publications.
      _
      Co-Authors
      People in Profiles who have published with this person.
      _
      Similar People
      People who share similar concepts with this person.
      _
      Same Department