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John Shen

TitleAssociate Physician
InstitutionUniversity of California San Diego
DepartmentMedicine
Address9500 Gilman Drive #0688
La Jolla CA 92093
Phone858-822-3092
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shen J, Ideker T. Synthetic Lethal Networks for Precision Oncology: Promises and Pitfalls. J Mol Biol. 2018 Jun 19. PMID: 29932943.
      View in: PubMed
    2. Zhang W, Bojorquez-Gomez A, Velez DO, Xu G, Sanchez KS, Shen J, Chen K, Licon K, Melton C, Olson KM, Yu MK, Huang JK, Carter H, Farley EK, Snyder M, Fraley SI, Kreisberg JF, Ideker T. A global transcriptional network connecting noncoding mutations to changes in tumor gene expression. Nat Genet. 2018 Apr; 50(4):613-620. PMID: 29610481.
      View in: PubMed
    3. Shen J, Ideker T. Correcting CRISPR for copy number. Nat Genet. 2017 Nov 29; 49(12):1674-1675. PMID: 29186130.
      View in: PubMed
    4. Shen J, Zhao D, Sasik R, Luebeck J, Birmingham A, Bojorquez-Gomez A, Licon K, Klepper K, Pekin D, Beckett AN, Sanchez KS, Thomas A, Kuo CC, Du D, Roguev A, Lewis NE, Chang AN, Kreisberg JF, Krogan N, Qi L, Ideker T, Mali P. Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions. Nat Methods. 2017 Jun; 14(6):573-576. PMID: 28319113.
      View in: PubMed
    5. Srivas R, Shen J, Yang CC, Sun SM, Li J, Gross AM, Jensen J, Licon K, Bojorquez-Gomez A, Klepper K, Huang J, Pekin D, Xu JL, Yeerna H, Sivaganesh V, Kollenstart L, van Attikum H, Aza-Blanc P, Sobol RW, Ideker T. A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy. Mol Cell. 2016 08 04; 63(3):514-25. PMID: 27453043.
      View in: PubMed
    6. Johnson TC, Chin MR, Han T, Shen J, Rana T, Siegel D. Synthesis of Eupalinilide E, a Promoter of Human Hematopoietic Stem and Progenitor Cell Expansion. J Am Chem Soc. 2016 05 11; 138(18):6068-73. PMID: 27096704.
      View in: PubMed
    7. Shen J, Srivas R, Gross A, Li J, Jaehnig EJ, Sun SM, Bojorquez-Gomez A, Licon K, Sivaganesh V, Xu JL, Klepper K, Yeerna H, Pekin D, Qiu CP, van Attikum H, Sobol RW, Ideker T. Chemogenetic profiling identifies RAD17 as synthetically lethal with checkpoint kinase inhibition. Oncotarget. 2015 Nov 03; 6(34):35755-69. PMID: 26437225; PMCID: PMC4742139.
    8. Choueiri MB, Shen J, Gross AM, Huang JK, Ideker T, Fanta P. ERCC1 and TS Expression as Prognostic and Predictive Biomarkers in Metastatic Colon Cancer. PLoS One. 2015; 10(6):e0126898. PMID: 26083491; PMCID: PMC4470586.
    9. Gross AM, Orosco RK, Shen J, Egloff AM, Carter H, Hofree M, Choueiri M, Coffey CS, Lippman SM, Hayes DN, Cohen EE, Grandis JR, Nguyen QT, Ideker T. Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss. Nat Genet. 2014 Sep; 46(9):939-43. PMID: 25086664; PMCID: PMC4146706.
    10. Ghashghaei R, Popa R, Shen J. Evans syndrome. Am J Med. 2013 Nov; 126(11):e7-8. PMID: 24157305.
      View in: PubMed
    11. Hofree M, Shen J, Carter H, Gross A, Ideker T. Network-based stratification of tumor mutations. Nat Methods. 2013 Nov; 10(11):1108-15. PMID: 24037242; PMCID: PMC3866081.