John Brock

Title(s)	ASSOC PROJ SCIENTIST, Neurosciences
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Research

Research Activities and Funding

SCI Consortium Study: Neural Stem Cell Transplantation for Cervical Spinal Cord Injury
NIH I01RX002626May 1, 2019 - Apr 30, 2024
Role: Principal Investigator

DREADD Modulation of Human NSCs to Accelerate Neuronal Maturation
NIH I21RX002708Jan 1, 2018 - Dec 31, 2019
Role: Principal Investigator

Transplantation of Human Neural Stem Cells for Treatment of Chronic SCI
NIH I01RX001045Apr 1, 2014 - Sep 30, 2017
Role: Principal Investigator

Molecular mechanisms of spinal cord plasticity
NIH F31NS044718Aug 1, 2002
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Rhesus macaque versus rat divergence in the corticospinal projectome. Neuron. 2022 09 21; 110(18):2970-2983.e4. Sinopoulou E, Rosenzweig ES, Conner JM, Gibbs D, Weinholtz CA, Weber JL, Brock JH, Nout-Lomas YS, Ovruchesky E, Takashima Y, Biane JS, Kumamaru H, Havton LA, Beattie MS, Bresnahan JC, Tuszynski MH. PMID: 35917818; PMCID: PMC9509478.

View in: PubMed Mentions: 6 Fields:
Neu Neurology
Translation:Animals Cells
Chondroitinase improves anatomical and functional outcomes after primate spinal cord injury. Nat Neurosci. 2019 08; 22(8):1269-1275. Rosenzweig ES, Salegio EA, Liang JJ, Weber JL, Weinholtz CA, Brock JH, Moseanko R, Hawbecker S, Pender R, Cruzen CL, Iaci JF, Caggiano AO, Blight AR, Haenzi B, Huie JR, Havton LA, Nout-Lomas YS, Fawcett JW, Ferguson AR, Beattie MS, Bresnahan JC, Tuszynski MH. PMID: 31235933; PMCID: PMC6693679.

View in: PubMed Mentions: 53 Fields:
Neu Neurology
Translation:Animals Cells
Restorative effects of human neural stem cell grafts on the primate spinal cord. Nat Med. 2018 05; 24(4):484-490. Rosenzweig ES, Brock JH, Lu P, Kumamaru H, Salegio EA, Kadoya K, Weber JL, Liang JJ, Moseanko R, Hawbecker S, Huie JR, Havton LA, Nout-Lomas YS, Ferguson AR, Beattie MS, Bresnahan JC, Tuszynski MH. PMID: 29480894; PMCID: PMC5922761.

View in: PubMed Mentions: 143 Fields:
Med Medicine (General)Mol Molecular Biology
Translation:Humans Animals Cells
Bone Marrow Stromal Cell Intraspinal Transplants Fail to Improve Motor Outcomes in a Severe Model of Spinal Cord Injury. J Neurotrauma. 2016 06 15; 33(12):1103-14. Brock JH, Graham L, Staufenberg E, Collyer E, Koffler J, Tuszynski MH. PMID: 26414795; PMCID: PMC4904236.

View in: PubMed Mentions: 13 Fields:
Neu Neurology Tra Traumatology
Translation:Animals Cells
Leveraging biomedical informatics for assessing plasticity and repair in primate spinal cord injury. Brain Res. 2015 Sep 04; 1619:124-38. Nielson JL, Haefeli J, Salegio EA, Liu AW, Guandique CF, Stück ED, Hawbecker S, Moseanko R, Strand SC, Zdunowski S, Brock JH, Roy RR, Rosenzweig ES, Nout-Lomas YS, Courtine G, Havton LA, Steward O, Reggie Edgerton V, Tuszynski MH, Beattie MS, Bresnahan JC, Ferguson AR. PMID: 25451131; PMCID: PMC4418964.

View in: PubMed Mentions: 9 Fields:
Bra Brain
Translation:Humans Animals
Development of a database for translational spinal cord injury research. J Neurotrauma. 2014 Nov 01; 31(21):1789-99. Nielson JL, Guandique CF, Liu AW, Burke DA, Lash AT, Moseanko R, Hawbecker S, Strand SC, Zdunowski S, Irvine KA, Brock JH, Nout-Lomas YS, Gensel JC, Anderson KD, Segal MR, Rosenzweig ES, Magnuson DS, Whittemore SR, McTigue DM, Popovich PG, Rabchevsky AG, Scheff SW, Steward O, Courtine G, Edgerton VR, Tuszynski MH, Beattie MS, Bresnahan JC, Ferguson AR. PMID: 25077610; PMCID: PMC4186058.

View in: PubMed Mentions: 30 Fields:
Neu Neurology Tra Traumatology
Translation:Animals
Animal models of neurologic disorders: a nonhuman primate model of spinal cord injury. Neurotherapeutics. 2012 Apr; 9(2):380-92. Nout YS, Rosenzweig ES, Brock JH, Strand SC, Moseanko R, Hawbecker S, Zdunowski S, Nielson JL, Roy RR, Courtine G, Ferguson AR, Edgerton VR, Beattie MS, Bresnahan JC, Tuszynski MH. PMID: 22427157; PMCID: PMC3337011.

View in: PubMed Mentions: 37 Fields:
Neu Neurology
Translation:Humans Animals
Methods for functional assessment after C7 spinal cord hemisection in the rhesus monkey. Neurorehabil Neural Repair. 2012 Jul-Aug; 26(6):556-69. Nout YS, Ferguson AR, Strand SC, Moseanko R, Hawbecker S, Zdunowski S, Nielson JL, Roy RR, Zhong H, Rosenzweig ES, Brock JH, Courtine G, Edgerton VR, Tuszynski MH, Beattie MS, Bresnahan JC. PMID: 22331214; PMCID: PMC3468651.

View in: PubMed Mentions: 18 Fields:
Neu Neurology Phy Physical and Rehabilitation Me
Translation:Animals
Neuropathic pain- and glial derived neurotrophic factor-associated regulation of cadherins in spinal circuits of the dorsal horn. Pain. 2011 Apr; 152(4):924-935. Patil SB, Brock JH, Colman DR, Huntley GW. PMID: 21316153.

View in: PubMed Mentions: 8 Fields:
Neu Neurology Psy Psychophysiology
Translation:Animals
Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury. Nat Neurosci. 2010 Dec; 13(12):1505-10. Rosenzweig ES, Courtine G, Jindrich DL, Brock JH, Ferguson AR, Strand SC, Nout YS, Roy RR, Miller DM, Beattie MS, Havton LA, Bresnahan JC, Edgerton VR, Tuszynski MH. PMID: 21076427; PMCID: PMC3144760.

View in: PubMed Mentions: 173 Fields:
Neu Neurology
Translation:Animals
Local and remote growth factor effects after primate spinal cord injury. J Neurosci. 2010 Jul 21; 30(29):9728-37. Brock JH, Rosenzweig ES, Blesch A, Moseanko R, Havton LA, Edgerton VR, Tuszynski MH. PMID: 20660255; PMCID: PMC2927098.

View in: PubMed Mentions: 47 Fields:
Neu Neurology
Translation:Animals Cells
Extensive spinal decussation and bilateral termination of cervical corticospinal projections in rhesus monkeys. J Comp Neurol. 2009 Mar 10; 513(2):151-63. Rosenzweig ES, Brock JH, Culbertson MD, Lu P, Moseanko R, Edgerton VR, Havton LA, Tuszynski MH. PMID: 19125408; PMCID: PMC2706096.

View in: PubMed Mentions: 76 Fields:
Neu Neurology
Translation:Animals Cells
Distribution and injury-induced plasticity of cadherins in relationship to identified synaptic circuitry in adult rat spinal cord. J Neurosci. 2004 Oct 06; 24(40):8806-17. Brock JH, Elste A, Huntley GW. PMID: 15470146; PMCID: PMC6729957.

View in: PubMed Mentions: 8 Fields:
Neu Neurology
Translation:Animals Cells