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John Brock

Title(s)Associate Project Scientist, Neurosciences
SchoolHealth Sciences
Phone858-822-2140
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    Collapse Research 
    Collapse Research Activities and Funding
    Neural Stem Cell Transplantation for Cervical Spinal Cord Injury
    VA I01RX002626May 1, 2019 - Apr 30, 2024
    Role: Principal Investigator
    DREADD Modulation of Human NSCs to Accelerate Neuronal Maturation
    VA I21RX002708Jan 1, 2018 - Dec 31, 2019
    Role: Principal Investigator
    Transplantation of Human Neural Stem Cells for Treatment of Chronic SCI
    VA I01RX001045Apr 1, 2014 - Mar 31, 2017
    Role: Principal Investigator
    Molecular mechanisms of spinal cord plasticity
    NIH/NINDS F31NS044718Aug 1, 2002
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Rosenzweig ES, Salegio EA, Liang JJ, Weber JL, Weinholtz CA, Brock JH, Moseanko R, Hawbecker S, Pender R, Cruzen CL, Iaci JF, Caggiano AO, Blight AR, Haenzi B, Huie JR, Havton LA, Nout-Lomas YS, Fawcett JW, Ferguson AR, Beattie MS, Bresnahan JC, Tuszynski MH. Chondroitinase improves anatomical and functional outcomes after primate spinal cord injury. Nat Neurosci. 2019 Jun 24. PMID: 31235933.
      View in: PubMed
    2. Rosenzweig ES, Brock JH, Lu P, Kumamaru H, Salegio EA, Kadoya K, Weber JL, Liang JJ, Moseanko R, Hawbecker S, Huie JR, Havton LA, Nout-Lomas YS, Ferguson AR, Beattie MS, Bresnahan JC, Tuszynski MH. Restorative effects of human neural stem cell grafts on the primate spinal cord. Nat Med. 2018 May; 24(4):484-490. PMID: 29480894.
      View in: PubMed
    3. Brock JH, Graham L, Staufenberg E, Collyer E, Koffler J, Tuszynski MH. Bone Marrow Stromal Cell Intraspinal Transplants Fail to Improve Motor Outcomes in a Severe Model of Spinal Cord Injury. J Neurotrauma. 2016 06 15; 33(12):1103-14. PMID: 26414795.
      View in: PubMed
    4. Nielson JL, Haefeli J, Salegio EA, Liu AW, Guandique CF, Stück ED, Hawbecker S, Moseanko R, Strand SC, Zdunowski S, Brock JH, Roy RR, Rosenzweig ES, Nout-Lomas YS, Courtine G, Havton LA, Steward O, Reggie Edgerton V, Tuszynski MH, Beattie MS, Bresnahan JC, Ferguson AR. Leveraging biomedical informatics for assessing plasticity and repair in primate spinal cord injury. Brain Res. 2015 Sep 04; 1619:124-38. PMID: 25451131.
      View in: PubMed
    5. Nielson JL, Guandique CF, Liu AW, Burke DA, Lash AT, Moseanko R, Hawbecker S, Strand SC, Zdunowski S, Irvine KA, Brock JH, Nout-Lomas YS, Gensel JC, Anderson KD, Segal MR, Rosenzweig ES, Magnuson DS, Whittemore SR, McTigue DM, Popovich PG, Rabchevsky AG, Scheff SW, Steward O, Courtine G, Edgerton VR, Tuszynski MH, Beattie MS, Bresnahan JC, Ferguson AR. Development of a database for translational spinal cord injury research. J Neurotrauma. 2014 Nov 01; 31(21):1789-99. PMID: 25077610; PMCID: PMC4186058.
      View in: PubMed, PubMed Central
    6. Nout YS, Rosenzweig ES, Brock JH, Strand SC, Moseanko R, Hawbecker S, Zdunowski S, Nielson JL, Roy RR, Courtine G, Ferguson AR, Edgerton VR, Beattie MS, Bresnahan JC, Tuszynski MH. Animal models of neurologic disorders: a nonhuman primate model of spinal cord injury. Neurotherapeutics. 2012 Apr; 9(2):380-92. PMID: 22427157; PMCID: PMC3337011.
      View in: PubMed, PubMed Central
    7. Nout YS, Ferguson AR, Strand SC, Moseanko R, Hawbecker S, Zdunowski S, Nielson JL, Roy RR, Zhong H, Rosenzweig ES, Brock JH, Courtine G, Edgerton VR, Tuszynski MH, Beattie MS, Bresnahan JC. Methods for functional assessment after C7 spinal cord hemisection in the rhesus monkey. Neurorehabil Neural Repair. 2012 Jul-Aug; 26(6):556-69. PMID: 22331214; PMCID: PMC3468651.
      View in: PubMed, PubMed Central
    8. Patil SB, Brock JH, Colman DR, Huntley GW. Neuropathic pain- and glial derived neurotrophic factor-associated regulation of cadherins in spinal circuits of the dorsal horn. Pain. 2011 Apr; 152(4):924-35. PMID: 21316153.
      View in: PubMed
    9. Rosenzweig ES, Courtine G, Jindrich DL, Brock JH, Ferguson AR, Strand SC, Nout YS, Roy RR, Miller DM, Beattie MS, Havton LA, Bresnahan JC, Edgerton VR, Tuszynski MH. Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury. Nat Neurosci. 2010 Dec; 13(12):1505-10. PMID: 21076427; PMCID: PMC3144760.
      View in: PubMed, PubMed Central
    10. Brock JH, Rosenzweig ES, Blesch A, Moseanko R, Havton LA, Edgerton VR, Tuszynski MH. Local and remote growth factor effects after primate spinal cord injury. J Neurosci. 2010 Jul 21; 30(29):9728-37. PMID: 20660255; PMCID: PMC2927098.
      View in: PubMed, PubMed Central
    11. Rosenzweig ES, Brock JH, Culbertson MD, Lu P, Moseanko R, Edgerton VR, Havton LA, Tuszynski MH. Extensive spinal decussation and bilateral termination of cervical corticospinal projections in rhesus monkeys. J Comp Neurol. 2009 Mar 10; 513(2):151-63. PMID: 19125408; PMCID: PMC2706096.
      View in: PubMed, PubMed Central
    12. Brock JH, Elste A, Huntley GW. Distribution and injury-induced plasticity of cadherins in relationship to identified synaptic circuitry in adult rat spinal cord. J Neurosci. 2004 Oct 06; 24(40):8806-17. PMID: 15470146.
      View in: PubMed
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