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Joel Linden

TitleAdjunct Professor
InstitutionUniversity of California San Diego
DepartmentPharmacology
Address9500 Gilman Drive #0636
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    A Controlled Clinical Trial of Regadenoson in Sickle Cell Anemia
    NIH/NHLBI P50HL110790Jul 15, 2012 - Jun 30, 2017
    Role: Co-Principal Investigator
    Biomarkers of Inflammation and Vaso-occlusion in Sickle Cell Disease
    NIH/NHLBI R01HL111969Jan 1, 2012 - Dec 31, 2016
    Role: Principal Investigator
    Lymphocyte Activation in Sickle Cell Lung Disease
    NIH/NHLBI R01HL095704May 1, 2010 - Apr 30, 2015
    Role: Principal Investigator
    CTRIP: Treatment of Sickle Cell Crisis with inhibitors of NKT cell activation
    NIH/NHLBI RC2HL101367Sep 30, 2009 - Aug 31, 2012
    Role: Principal Investigator
    ROLE OF INFLAMMATION IN PULMONARY INJURY
    NIH/NHLBI P01HL073361Aug 16, 2004 - Apr 30, 2010
    Role: Principal Investigator
    Allosteric Enhancement of Adenosine Receptors
    NIH/NHLBI R01HL056111Apr 20, 1996 - Dec 31, 2010
    Role: Principal Investigator
    ADENOSINE RECEPTOR-G PROTEIN COUPLING
    NIH/NHLBI R01HL049078Jan 1, 1993 - Dec 31, 1996
    Role: Principal Investigator
    PURIFICATION AND CHARACTERIZATION OF ADENOSINE RECEPTORS
    NIH/NHLBI R55HL037942Sep 30, 1991 - Dec 31, 1991
    Role: Principal Investigator
    Purification &Characterization of Adenosine Receptors
    NIH/NHLBI R01HL037942Jul 1, 1986 - Nov 30, 2010
    Role: Principal Investigator
    ADENOSINE AND BETA-ADRENERGIC RECEPTORS IN HEART CELLS
    NIH/NHLBI R01HL031432Feb 1, 1984 - Jan 31, 1987
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Franco A, Kumar J, Lin G, Behnamfar N, Hsieh LE, Shimizu C, Tremoulet AH, Burns JC, Linden J. Pediatric tolerogenic DCs expressing CD4 and immunoglobulin-like transcript receptor (ILT)-4 secrete IL-10 in response to Fc and adenosine. Eur J Immunol. 2018 Mar; 48(3):482-491. PMID: 29244203.
      View in: PubMed
    2. Belcik JT, Davidson BP, Xie A, Wu MD, Yadava M, Qi Y, Liang S, Chon CR, Ammi AY, Field J, Harmann L, Chilian WM, Linden J, Lindner JR. Augmentation of Muscle Blood Flow by Ultrasound Cavitation Is Mediated by ATP and Purinergic Signaling. Circulation. 2017 Mar 28; 135(13):1240-1252. PMID: 28174191.
      View in: PubMed
    3. Belcik JT, Mott BH, Xie A, Zhao Y, Kim S, Lindner NJ, Ammi A, Linden J, Lindner JR. Augmentation of limb perfusion and reversal of tissue ischemia produced by ultrasound-mediated microbubble cavitation. Circ Cardiovasc Imaging. 2015 Apr; 8(4). PMID: 25834183; PMCID: PMC4384163.
    4. Kennedy DP, McRobb FM, Leonhardt SA, Purdy M, Figler H, Marshall MA, Chordia M, Figler R, Linden J, Abagyan R, Yeager M. The second extracellular loop of the adenosine A1 receptor mediates activity of allosteric enhancers. Mol Pharmacol. 2014 Feb; 85(2):301-9. PMID: 24217444; PMCID: PMC3913357.
    5. Sun WC, Moore JN, Hurley DJ, Vandenplas ML, Linden J, Murray TF. Pharmacologic characterization of novel adenosine A2A receptor agonists in equine neutrophils. Am J Vet Res. 2007 Sep; 68(9):981-7. PMID: 17764413.
      View in: PubMed
    6. Crookes BA, Cohn SM, Bonet H, Burton EA, Nelson J, Majetschak M, Varon AJ, Linden J, Proctor KG. Building a better fluid for emergency resuscitation of traumatic brain injury. J Trauma. 2004 Sep; 57(3):547-54. PMID: 15454801.
      View in: PubMed