Jeremy Rich

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Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    Duke University School of Medicine, Durham, NCMHS05/2009Clinical Research Training Program
    Baldwin Wallace University, Parma, OHMBA05/2016Health Care
    Duke University Medical Center, Durham, NC06/1998Neuro-Oncology
    Johns Hopkins Hospital, Baltimore, MD06/1997Neurology
    Johns Hopkins Hospital, Baltimore, MD06/1994Internal Medicine
    Duke University School of Medicine, Durham, NCMD05/1993Medicine
    Washington University, St. Louis, MOB.S.05/1989Electrical Engineering

    Collapse Overview 
    Collapse Websites

    Collapse Research 
    Collapse Research Activities and Funding
    Targeting the Circadian Rhythm in Glioblastoma Stem Cells
    NIH R01CA238662Dec 1, 2019 - Nov 30, 2024
    Role: Principal Investigator
    Dual Targeting of Brain Tumor Initiating Cells through Inhibition of BMI1 and EZH2 (R01NS103434)
    NIH R01NS103434Sep 30, 2017 - Jun 30, 2022
    Role: Principal Investigator
    Dynamic Complexity of Brain Tumor Stem Cells (R35CA197718)
    NIH R35CA197718Aug 1, 2015 - Aug 31, 2022
    Role: Principal Investigator
    Instructive Cues in Glioblastoma Hierarchies
    NIH R01CA171652Aug 15, 2014 - Jul 31, 2015
    Role: Principal Investigator
    Energy Stress in Brain Tumor Initiating Stem Cells
    NIH R01NS089272Aug 1, 2014 - Jul 31, 2019
    Role: Principal Investigator
    Metabolism Informs Intertumoral & Intratumoral Heterogeneity
    NIH R01NS087913Apr 15, 2014 - Feb 28, 2019
    Role: Co-Principal Investigator
    Targeting Ferritin in Glioblastoma
    NIH R01CA169117Jul 1, 2013 - Apr 30, 2018
    Role: Co-Principal Investigator
    Targeting Brain Tumor Stem Cells Through Novel Therapeutic Combinations
    NIH R01CA154130Jul 1, 2010 - Dec 31, 2014
    Role: Principal Investigator
    Stem Cell-Like Glioma Cells in Angiogenesis
    NIH R01CA129958Apr 7, 2008 - Dec 31, 2013
    Role: Principal Investigator
    TGFbeta-PTEN Interactions in Glioma Biology &Therapy
    NIH R01CA116659Aug 1, 2006 - Dec 31, 2011
    Role: Principal Investigator
    Molecular Mechanisms of SPARC Mediated Glioma Invasion
    NIH R01NS054276Feb 15, 2006 - Jan 31, 2011
    Role: Principal Investigator
    The Roles of Osteonectin and Osteoactivin in Gliomas
    NIH K02NS047409Jun 1, 2004 - Feb 28, 2009
    Role: Principal Investigator
    TGF beta and Brain Tumors
    NIH K08NS002055Jul 1, 1998 - Jun 30, 2003
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. 3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma. Nat Commun. 2023 Apr 21; 14(1):2300. Okonechnikov K, Camg?z A, Chapman O, Wani S, Park DE, H?bner JM, Chakraborty A, Pagadala M, Bump R, Chandran S, Kraft K, Acuna-Hidalgo R, Reid D, Sikkink K, Mauermann M, Juarez EF, Jenseit A, Robinson JT, Pajtler KW, Milde T, J?ger N, Fiesel P, Morgan L, Sridhar S, Coufal NG, Levy M, Malicki D, Hobbs C, Kingsmore S, Nahas S, Snuderl M, Crawford J, Wechsler-Reya RJ, Davidson TB, Cotter J, Michaiel G, Fleischhack G, Mundlos S, Schmitt A, Carter H, Michealraj KA, Kumar SA, Taylor MD, Rich J, Buchholz F, Mesirov JP, Pfister SM, Ay F, Dixon JR, Kool M, Chavez L. PMID: 37085539; PMCID: PMC10121654.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma. Cancer Discov. 2023 04 03; 13(4):974-1001. Ye Z, Ai X, Yang K, Yang Z, Fei F, Liao X, Qiu Z, Gimple RC, Yuan H, Huang H, Gong Y, Xiao C, Yue J, Huang L, Saulnier O, Wang W, Zhang P, Dai L, Wang X, Wang X, Ahn YH, You C, Xu J, Wan X, Taylor MD, Zhao L, Rich JN, Zhou S. PMID: 36649564; PMCID: PMC10073346.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting. JCI Insight. 2023 03 22; 8(6). Gimple RC, Zhang G, Wang S, Huang T, Lee J, Taori S, Lv D, Dixit D, Halbert ME, Morton AR, Kidwell RL, Dong Z, Prager BC, Kim LJ, Qiu Z, Zhao L, Xie Q, Wu Q, Agnihotri S, Rich JN. PMID: 36795488; PMCID: PMC10070110.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. SREBP2 maintains glioblastoma stem cells through keeping the balance between cholesterol biosynthesis and uptake. Neuro Oncol. 2023 Mar 19. Gu D, Zhou F, You H, Gao J, Kang T, Dixit D, Wu Q, Yang K, Ci S, Shan D, Fan X, Yuan W, Zhang Q, Lu C, Li D, Zhao N, Shi Z, Gao W, Lin F, Man J, Wang Q, Qian X, Mack SC, Tao W, Agnihotri S, Zhang N, You Y, Rich JN, Zhang J, Wang X. PMID: 36934350.
      View in: PubMed   Mentions:    Fields:    
    5. A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis. Nat Cell Biol. 2023 03; 25(3):493-507. Zou H, Poore B, Brown EE, Qian J, Xie B, Asimakidou E, Razskazovskiy V, Ayrapetian D, Sharma V, Xia S, Liu F, Chen A, Guan Y, Li Z, Wanggou S, Saulnier O, Ly M, Fellows-Mayle W, Xi G, Tomita T, Resnick AC, Mack SC, Raabe EH, Eberhart CG, Sun D, Stronach BE, Agnihotri S, Kohanbash G, Lu S, Herrup K, Rich JN, Gittes GK, Broniscer A, Hu Z, Li X, Pollack IF, Friedlander RM, Hainer SJ, Taylor MD, Hu B. PMID: 36849558; PMCID: PMC10014585.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy. Neuro Oncol. 2023 02 14; 25(2):248-260. Lim YC, Jensen KE, Aguilar-Morante D, Vardouli L, Vitting-Seerup K, Gimple RC, Wu Q, Pedersen H, Elbaek KJ, Gromova I, Ihnatko R, Kristensen BW, Petersen JK, Skjoth-Rasmussen J, Flavahan W, Rich JN, Hamerlik P. PMID: 35608632; PMCID: PMC9925708.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma. Genes Dev. 2023 02 01; 37(3-4):86-102. Mitchell K, Sprowls SA, Arora S, Shakya S, Silver DJ, Goins CM, Wallace L, Roversi G, Schafer RE, Kay K, Miller TE, Lauko A, Bassett J, Kashyap A, D'Amato Kass J, Mulkearns-Hubert EE, Johnson S, Alvarado J, Rich JN, Holland EC, Paddison PJ, Patel AP, Stauffer SR, Hubert CG, Lathia JD. PMID: 36732025; PMCID: PMC10069451.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling. J Clin Invest. 2023 01 17; 133(2). Lee D, Gimple RC, Wu X, Prager BC, Qiu Z, Wu Q, Daggubati V, Mariappan A, Gopalakrishnan J, Sarkisian MR, Raleigh DR, Rich JN. PMID: 36394953; PMCID: PMC9843063.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle. Proc Natl Acad Sci U S A. 2023 01 10; 120(2):e2214829120. Qu M, Zhang G, Qu H, Vu A, Wu R, Tsukamoto H, Jia Z, Huang W, Lenz HJ, Rich JN, Kay SA. PMID: 36595671; PMCID: PMC9926257.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. ABTC-0904: targeting glioma stem cells in GBM: a phase 0/II study of hedgehog pathway inhibitor GDC-0449. J Neurooncol. 2023 Jan; 161(1):33-43. Sloan AE, Nock CJ, Ye X, Buerki R, Chang S, Lesser G, Norden A, Cloughesy T, Olson J, Kerstetter-Fogle A, Rich J, Fisher J, Desideri S, Takebe N, Timmer W, Grossman S, Prados M. PMID: 36581779.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. NIR Drives Glioblastoma Growth by Promoting Ribosomal DNA Transcription in Glioma Stem Cells. Neuro Oncol. 2022 Dec 15. Tao W, Lei H, Luo W, Huang Z, Ling P, Guo M, Wan L, Zhai K, Huang Q, Wu Q, Xu S, Zeng L, Wang X, Dong Z, Rich JN, Bao S. PMID: 36521011.
      View in: PubMed   Mentions:    Fields:    
    12. Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022 Nov 29. Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudière-Morrison L, Mercier AL, Shokouhian M, Suárez RA, Ly M, Borlase S, Scott DS, Vladoiu MC, Farooq H, Sirbu O, Nakashima T, Nambu S, Funakoshi Y, Bahcheli A, Diaz-Mejia JJ, Golser J, Bach K, Phuong-Bao T, Skowron P, Wang EY, Kumar SA, Balin P, Visvanathan A, Lee JJY, Ayoub R, Chen X, Chen X, Mungall KL, Luu B, Bérubé P, Wang YC, Pfister SM, Kim SK, Delattre O, Bourdeaut F, Doz F, Masliah-Planchon J, Grajkowska WA, Loukides J, Dirks P, Fèvre-Montange M, Jouvet A, French PJ, Kros JM, Zitterbart K, Bailey SD, Eberhart CG, Rao AAN, Giannini C, Olson JM, Garami M, Hauser P, Phillips JJ, Ra YS, de Torres C, Mora J, Li KKW, Ng HK, Poon WS, Pollack IF, López-Aguilar E, Gillespie GY, Van Meter TE, Shofuda T, Vibhakar R, Thompson RC, Cooper MK, Rubin JB, Kumabe T, Jung S, Lach B, Iolascon A, Ferrucci V, de Antonellis P, Zollo M, Cinalli G, Robinson S, Stearns DS, Van Meir EG, Porrati P, Finocchiaro G, Massimino M, Carlotti CG, Faria CC, Roussel MF, Boop F, Chan JA, Aldinger KA, Razavi F, Silvestri E, McLendon RE, Thompson EM, Ansari M, Garre ML, Chico F, Eguía P, Pérezpeña M, Morrissy AS, Cavalli FMG, Wu X, Daniels C, Rich JN, Jones SJM, Moore RA, Marra MA, Huang X, Reimand J, Sorensen PH, Wechsler-Reya RJ, Weiss WA, Pugh TJ, Garzia L, Kleinman CL, Stein LD, Jabado N, Malkin D, Ayrault O, Golden JA, Ellison DW, Doble B, Ramaswamy V, Werbowetski-Ogilvie TE, Suzuki H, Millen KJ, Taylor MD. PMID: 36446943.
      View in: PubMed   Mentions: 1     Fields:    
    13. Glioma stem cells activate platelets by plasma-independent thrombin production to promote glioblastoma tumorigenesis. Neurooncol Adv. 2022 Jan-Dec; 4(1):vdac172. Sloan AR, Lee-Poturalski C, Hoffman HC, Harris PL, Elder TE, Richardson B, Kerstetter-Fogle A, Cioffi G, Schroer J, Desai A, Cameron M, Barnholtz-Sloan J, Rich J, Jankowsky E, Sen Gupta A, Sloan AE. PMID: 36452274; PMCID: PMC9700385.
      View in: PubMed   Mentions:
    14. Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022 09; 609(7929):1021-1028. Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudière-Morrison L, Mercier AL, Shokouhian M, Suárez RA, Ly M, Borlase S, Scott DS, Vladoiu MC, Farooq H, Sirbu O, Nakashima T, Nambu S, Funakoshi Y, Bahcheli A, Diaz-Mejia JJ, Golser J, Bach K, Phuong-Bao T, Skowron P, Wang EY, Kumar SA, Balin P, Visvanathan A, Lee JJY, Ayoub R, Chen X, Chen X, Mungall KL, Luu B, Bérubé P, Wang YC, Pfister SM, Kim SK, Delattre O, Bourdeaut F, Doz F, Masliah-Planchon J, Grajkowska WA, Loukides J, Dirks P, Fèvre-Montange M, Jouvet A, French PJ, Kros JM, Zitterbart K, Bailey SD, Eberhart CG, Rao AAN, Giannini C, Olson JM, Garami M, Hauser P, Phillips JJ, Ra YS, de Torres C, Mora J, Li KKW, Ng HK, Poon WS, Pollack IF, López-Aguilar E, Gillespie GY, Van Meter TE, Shofuda T, Vibhakar R, Thompson RC, Cooper MK, Rubin JB, Kumabe T, Jung S, Lach B, Iolascon A, Ferrucci V, de Antonellis P, Zollo M, Cinalli G, Robinson S, Stearns DS, Van Meir EG, Porrati P, Finocchiaro G, Massimino M, Carlotti CG, Faria CC, Roussel MF, Boop F, Chan JA, Aldinger KA, Razavi F, Silvestri E, McLendon RE, Thompson EM, Ansari M, Garre ML, Chico F, Eguía P, Pérezpeña M, Morrissy AS, Cavalli FMG, Wu X, Daniels C, Rich JN, Jones SJM, Moore RA, Marra MA, Huang X, Reimand J, Sorensen PH, Wechsler-Reya RJ, Weiss WA, Pugh TJ, Garzia L, Kleinman CL, Stein LD, Jabado N, Malkin D, Ayrault O, Golden JA, Ellison DW, Doble B, Ramaswamy V, Werbowetski-Ogilvie TE, Suzuki H, Millen KJ, Taylor MD. PMID: 36131014; PMCID: PMC10026724.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    15. β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages. Cancer Res. 2022 Sep 16; 82(18):3321-3334. Li D, Zhang Q, Li L, Chen K, Yang J, Dixit D, Gimple RC, Ci S, Lu C, Hu L, Gao J, Shan D, Li Y, Zhang J, Shi Z, Gu D, Yuan W, Wu Q, Yang K, Zhao L, Qiu Z, Lv D, Gao W, Yang H, Lin F, Wang Q, Man J, Li C, Tao W, Agnihotri S, Qian X, Shi Y, You Y, Zhang N, Rich JN, Wang X. PMID: 35841593.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    16. SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus. Nat Commun. 2022 09 12; 13(1):5341. Branche E, Wang YT, Viramontes KM, Valls Cuevas JM, Xie J, Ana-Sosa-Batiz F, Shafee N, Duttke SH, McMillan RE, Clark AE, Nguyen MN, Garretson AF, Crames JJ, Spann NJ, Zhu Z, Rich JN, Spector DH, Benner C, Shresta S, Carlin AF. PMID: 36097162; PMCID: PMC9465152.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    17. Growth factor receptor signaling induces mitophagy through epitranscriptomic regulation. Autophagy. 2023 03; 19(3):1034-1035. Lv D, Yang K, Rich JN. PMID: 35980802; PMCID: PMC9980508.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    18. Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome. Nat Cancer. 2022 Jul; 3(7):899. Golbourn BJ, Halbert ME, Halligan K, Varadharajan S, Krug B, Mbah NE, Kabir N, Stanton AJ, Locke AL, Casillo SM, Zhao Y, Sanders LM, Cheney A, Mullett SJ, Chen A, Wassell M, Andren A, Perez J, Jane EP, Premkumar DRD, Koncar RF, Mirhadi S, McCarl LH, Chang YF, Wu YL, Gatesman TA, Cruz AF, Zapotocky M, Hu B, Kohanbash G, Wang X, Vartanian A, Moran MF, Lieberman F, Amankulor NM, Wendell SG, Vaske OM, Panigrahy A, Felker J, Bertrand KC, Kleinman CL, Rich JN, Friedlander RM, Broniscer A, Lyssiotis C, Jabado N, Pollack IF, Mack SC, Agnihotri S. PMID: 35739422.
      View in: PubMed   Mentions:    Fields:    
    19. Brain cancer stem cells: resilience through adaptive plasticity and hierarchical heterogeneity. Nat Rev Cancer. 2022 09; 22(9):497-514. Gimple RC, Yang K, Halbert ME, Agnihotri S, Rich JN. PMID: 35710946.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    20. PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine. Dev Cell. 2022 06 20; 57(12):1466-1481.e6. Lv D, Gimple RC, Zhong C, Wu Q, Yang K, Prager BC, Godugu B, Qiu Z, Zhao L, Zhang G, Dixit D, Lee D, Shen JZ, Li X, Xie Q, Wang X, Agnihotri S, Rich JN. PMID: 35659339; PMCID: PMC9239307.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    21. Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Nat Genet. 2022 05; 54(5):649-659. Choudhury A, Magill ST, Eaton CD, Prager BC, Chen WC, Cady MA, Seo K, Lucas CG, Casey-Clyde TJ, Vasudevan HN, Liu SJ, Villanueva-Meyer JE, Lam TC, Pu JK, Li LF, Leung GK, Swaney DL, Zhang MY, Chan JW, Qiu Z, Martin MV, Susko MS, Braunstein SE, Bush NAO, Schulte JD, Butowski N, Sneed PK, Berger MS, Krogan NJ, Perry A, Phillips JJ, Solomon DA, Costello JF, McDermott MW, Rich JN, Raleigh DR. PMID: 35534562; PMCID: PMC9374001.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    22. Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome. Nat Cancer. 2022 05; 3(5):629-648. Golbourn BJ, Halbert ME, Halligan K, Varadharajan S, Krug B, Mbah NE, Kabir N, Stanton AJ, Locke AL, Casillo SM, Zhao Y, Sanders LM, Cheney A, Mullett SJ, Chen A, Wassell M, Andren A, Perez J, Jane EP, Premkumar DRD, Koncar RF, Mirhadi S, McCarl LH, Chang YF, Wu YL, Gatesman TA, Cruz AF, Zapotocky M, Hu B, Kohanbash G, Wang X, Vartanian A, Moran MF, Lieberman F, Amankulor NM, Wendell SG, Vaske OM, Panigrahy A, Felker J, Bertrand KC, Kleinman CL, Rich JN, Friedlander RM, Broniscer A, Lyssiotis C, Jabado N, Pollack IF, Mack SC, Agnihotri S. PMID: 35422502; PMCID: PMC9551679.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    23. CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity. Nat Commun. 2022 04 07; 13(1):1899. Bernareggi D, Xie Q, Prager BC, Yun J, Cruz LS, Pham TV, Kim W, Lee X, Coffey M, Zalfa C, Azmoon P, Zhu H, Tamayo P, Rich JN, Kaufman DS. PMID: 35393416; PMCID: PMC8990014.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    24. Patient-derived explants as tumor models. Cancer Cell. 2022 04 11; 40(4):348-350. Hubert CG, Rich JN. PMID: 35364017.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    25. ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance. J Clin Invest. 2022 03 15; 132(6). Jiang L, Hao Y, Shao C, Wu Q, Prager BC, Gimple RC, Sulli G, Kim LJ, Zhang G, Qiu Z, Zhu Z, Fu XD, Rich JN. PMID: 35133980; PMCID: PMC8920333.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    26. USP33 deubiquitinates and stabilizes HIF-2alpha to promote hypoxia response in glioma stem cells. EMBO J. 2022 04 04; 41(7):e109187. Zhang A, Huang Z, Tao W, Zhai K, Wu Q, Rich JN, Zhou W, Bao S. PMID: 35191554; PMCID: PMC8982626.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    27. A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells. Mol Cell. 2022 03 17; 82(6):1123-1139.e8. Shen JZ, Qiu Z, Wu Q, Zhang G, Harris R, Sun D, Rantala J, Barshop WD, Zhao L, Lv D, Won KA, Wohlschlegel J, Sangfelt O, Laman H, Rich JN, Spruck C. PMID: 35182481; PMCID: PMC8934274.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    28. Glioblastoma stem cells reprogram chromatin in vivo to generate selective therapeutic dependencies on DPY30 and phosphodiesterases. Sci Transl Med. 2022 01 05; 14(626):eabf3917. Dixit D, Prager BC, Gimple RC, Miller TE, Wu Q, Yomtoubian S, Kidwell RL, Lv D, Zhao L, Qiu Z, Zhang G, Lee D, Park DE, Wechsler-Reya RJ, Wang X, Bao S, Rich JN. PMID: 34985972.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    29. Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma. Cancer Res. 2022 02 01; 82(3):377-390. Sen A, Prager BC, Zhong C, Park D, Zhu Z, Gimple RC, Wu Q, Bernatchez JA, Beck S, Clark AE, Siqueira-Neto JL, Rich JN, McVicker G. PMID: 34903607; PMCID: PMC9122831.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    30. Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug. Cell Rep. 2021 11 02; 37(5):109957. Bi J, Khan A, Tang J, Armando AM, Wu S, Zhang W, Gimple RC, Reed A, Jing H, Koga T, Wong IT, Gu Y, Miki S, Yang H, Prager B, Curtis EJ, Wainwright DA, Furnari FB, Rich JN, Cloughesy TF, Kornblum HI, Quehenberger O, Rzhetsky A, Cravatt BF, Mischel PS. PMID: 34731610; PMCID: PMC8856626.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    31. Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe. J Exp Med. 2021 11 01; 218(11). Zhang G, Dong Z, Gimple RC, Wolin A, Wu Q, Qiu Z, Wood LM, Shen JZ, Jiang L, Zhao L, Lv D, Prager BC, Kim LJY, Wang X, Zhang L, Anderson RL, Moore JK, Bao S, Keller TH, Lin G, Kang C, Hamerlik P, Zhao R, Ford HL, Rich JN. PMID: 34617969; PMCID: PMC8504185.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    32. Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells. Cancer Discov. 2022 02; 12(2):502-521. Qiu Z, Zhao L, Shen JZ, Liang Z, Wu Q, Yang K, Min L, Gimple RC, Yang Q, Bhargava S, Jin C, Kim C, Hinz D, Dixit D, Bernatchez JA, Prager BC, Zhang G, Dong Z, Lv D, Wang X, Kim LJY, Zhu Z, Jones KA, Zheng Y, Wang X, Siqueira-Neto JL, Chavez L, Fu XD, Spruck C, Rich JN. PMID: 34615656; PMCID: PMC8831451.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    33. Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase. Nucleic Acids Res. 2021 07 21; 49(13):7361-7374. Xia Z, Tang M, Ma J, Zhang H, Gimple RC, Prager BC, Tang H, Sun C, Liu F, Lin P, Mei Y, Du R, Rich JN, Xie Q. PMID: 34181729; PMCID: PMC8287920.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    34. A delicate initiation: Lipolysis of lipid droplets fuels glioblastoma. Mol Cell. 2021 07 01; 81(13):2686-2687. Yang K, Rich JN. PMID: 34214442.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    35. Inhibiting DNA-PK induces glioma stem cell differentiation and sensitizes glioblastoma to radiation in mice. Sci Transl Med. 2021 06 30; 13(600). Fang X, Huang Z, Zhai K, Huang Q, Tao W, Kim L, Wu Q, Almasan A, Yu JS, Li X, Stark GR, Rich JN, Bao S. PMID: 34193614.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    36. A vaccine for glioma. Nat Cancer. 2021 06; 2(6):584-586. Agnihotri S, Yang K, Mitchell DA, Rich JN. PMID: 35121939.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    37. Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches. Acta Neuropathol Commun. 2021 05 31; 9(1):101. Shakya S, Gromovsky AD, Hale JS, Knudsen AM, Prager B, Wallace LC, Penalva LOF, Brown HA, Kristensen BW, Rich JN, Lathia JD, Brown JM, Hubert CG. PMID: 34059134; PMCID: PMC8166002.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    38. Brd4-bound enhancers drive cell-intrinsic sex differences in glioblastoma. Proc Natl Acad Sci U S A. 2021 04 20; 118(16). Kfoury N, Qi Z, Prager BC, Wilkinson MN, Broestl L, Berrett KC, Moudgil A, Sankararaman S, Chen X, Gertz J, Rich JN, Mitra RD, Rubin JB. PMID: 33850013; PMCID: PMC8072233.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    39. PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response. Proc Natl Acad Sci U S A. 2021 04 20; 118(16). Li J, Kaneda MM, Ma J, Li M, Shepard RM, Patel K, Koga T, Sarver A, Furnari F, Xu B, Dhawan S, Ning J, Zhu H, Wu A, You G, Jiang T, Venteicher AS, Rich JN, Glass CK, Varner JA, Chen CC. PMID: 33846242; PMCID: PMC8072253.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    40. Phage display targeting identifies EYA1 as a regulator of glioblastoma stem cell maintenance and proliferation. Stem Cells. 2021 07; 39(7):853-865. Kim J, She C, Potez M, Huang P, Wu Q, Prager BC, Qiu Z, Bao S, Rich JN, Liu JKC. PMID: 33594762.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    41. Plasma cells shape the mesenchymal identity of ovarian cancers through transfer of exosome-derived microRNAs. Sci Adv. 2021 02; 7(9). Yang Z, Wang W, Zhao L, Wang X, Gimple RC, Xu L, Wang Y, Rich JN, Zhou S. PMID: 33627414; PMCID: PMC7904265.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    42. Zika virus oncolytic activity requires CD8+ T cells and is boosted by immune checkpoint blockade. JCI Insight. 2021 01 11; 6(1). Nair S, Mazzoccoli L, Jash A, Govero J, Bais SS, Hu T, Fontes-Garfias CR, Shan C, Okada H, Shresta S, Rich JN, Shi PY, Diamond MS, Chheda MG. PMID: 33232299; PMCID: PMC7821591.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    43. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell. 2021 01 21; 184(2):352-369.e23. Shen JZ, Qiu Z, Wu Q, Finlay D, Garcia G, Sun D, Rantala J, Barshop W, Hope JL, Gimple RC, Sangfelt O, Bradley LM, Wohlschlegel J, Rich JN, Spruck C. PMID: 33357448; PMCID: PMC8043252.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    44. Protein sumoylation with SUMO1 promoted by Pin1 in glioma stem cells augments glioblastoma malignancy. Neuro Oncol. 2020 12 18; 22(12):1809-1821. Zhang A, Tao W, Zhai K, Fang X, Huang Z, Yu JS, Sloan AE, Rich JN, Zhou W, Bao S. PMID: 32592588; PMCID: PMC7746948.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    45. CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies. Cancer Discov. 2021 05; 11(5):1192-1211. Wang D, Prager BC, Gimple RC, Aguilar B, Alizadeh D, Tang H, Lv D, Starr R, Brito A, Wu Q, Kim LJY, Qiu Z, Lin P, Lorenzini MH, Badie B, Forman SJ, Xie Q, Brown CE, Rich JN. PMID: 33328215; PMCID: PMC8406797.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    46. Zika virus is transmitted in neural progenitor cells via cell-to-cell spread and infection is inhibited by the autophagy inducer trehalose. J Virol. 2021 03 01; 95(5). Clark AE, Zhu Z, Krach F, Rich JN, Yeo GW, Spector DH. PMID: 33328307; PMCID: PMC8092816.
      View in: PubMed   Mentions: 2     Fields:    
    47. Biomaterials and 3D Bioprinting Strategies to Model Glioblastoma and the Blood-Brain Barrier. Adv Mater. 2021 Feb; 33(5):e2004776. Tang M, Rich JN, Chen S. PMID: 33326131; PMCID: PMC7854518.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    48. Adipocytes promote breast tumorigenesis through TAZ-dependent secretion of Resistin. Proc Natl Acad Sci U S A. 2020 12 29; 117(52):33295-33304. Gao Y, Chen X, He Q, Gimple RC, Liao Y, Wang L, Wu R, Xie Q, Rich JN, Shen K, Yuan Z. PMID: 33318171; PMCID: PMC7776784.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    49. SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells. EMBO Mol Med. 2020 12 07; 12(12):e12291. Tao W, Zhang A, Zhai K, Huang Z, Huang H, Zhou W, Huang Q, Fang X, Prager BC, Wang X, Wu Q, Sloan AE, Ahluwalia MS, Lathia JD, Yu JS, Rich JN, Bao S. PMID: 33124191; PMCID: PMC7721366.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    50. The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem Cells. Cancer Discov. 2021 02; 11(2):480-499. Dixit D, Prager BC, Gimple RC, Poh HX, Wang Y, Wu Q, Qiu Z, Kidwell RL, Kim LJY, Xie Q, Vitting-Seerup K, Bhargava S, Dong Z, Jiang L, Zhu Z, Hamerlik P, Jaffrey SR, Zhao JC, Wang X, Rich JN. PMID: 33023892; PMCID: PMC8110214.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    51. Reprogramming the microenvironment: tricks of tumor-derived astrocytes. Cell Res. 2020 08; 30(8):633-634. Zhang G, Rich JN. PMID: 32424205; PMCID: PMC7395723.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    52. The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies. Cancer Discov. 2020 11; 10(11):1722-1741. Prager BC, Vasudevan HN, Dixit D, Bernatchez JA, Wu Q, Wallace LC, Bhargava S, Lee D, King BH, Morton AR, Gimple RC, Pekmezci M, Zhu Z, Siqueira-Neto JL, Wang X, Xie Q, Chen C, Barnett GH, Vogelbaum MA, Mack SC, Chavez L, Perry A, Raleigh DR, Rich JN. PMID: 32703768; PMCID: PMC8194360.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    53. A Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries. N Engl J Med. 2020 07 09; 383(2):129-140. Bhasin S, Gill TM, Reuben DB, Latham NK, Ganz DA, Greene EJ, Dziura J, Basaria S, Gurwitz JH, Dykes PC, McMahon S, Storer TW, Gazarian P, Miller ME, Travison TG, Esserman D, Carnie MB, Goehring L, Fagan M, Greenspan SL, Alexander N, Wiggins J, Ko F, Siu AL, Volpi E, Wu AW, Rich J, Waring SC, Wallace RB, Casteel C, Resnick NM, Magaziner J, Charpentier P, Lu C, Araujo K, Rajeevan H, Meng C, Allore H, Brawley BF, Eder R, McGloin JM, Skokos EA, Duncan PW, Baker D, Boult C, Correa-de-Araujo R, Peduzzi P, STRIDE Trial Investigators. PMID: 32640131; PMCID: PMC7421468.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    54. Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma. Nat Commun. 2020 06 15; 11(1):3015. Tao W, Chu C, Zhou W, Huang Z, Zhai K, Fang X, Huang Q, Zhang A, Wang X, Yu X, Huang H, Wu Q, Sloan AE, Yu JS, Li X, Stark GR, Rich JN, Bao S. PMID: 32541784; PMCID: PMC7295765.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    55. Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions. Cell Res. 2020 10; 30(10):833-853. Tang M, Xie Q, Gimple RC, Zhong Z, Tam T, Tian J, Kidwell RL, Wu Q, Prager BC, Qiu Z, Yu A, Zhu Z, Mesci P, Jing H, Schimelman J, Wang P, Lee D, Lorenzini MH, Dixit D, Zhao L, Bhargava S, Miller TE, Wan X, Tang J, Sun B, Cravatt BF, Muotri AR, Chen S, Rich JN. PMID: 32499560; PMCID: PMC7608409.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    56. Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma. Cell. 2020 06 11; 181(6):1329-1345.e24. Michealraj KA, Kumar SA, Kim LJY, Cavalli FMG, Przelicki D, Wojcik JB, Delaidelli A, Bajic A, Saulnier O, MacLeod G, Vellanki RN, Vladoiu MC, Guilhamon P, Ong W, Lee JJY, Jiang Y, Holgado BL, Rasnitsyn A, Malik AA, Tsai R, Richman CM, Juraschka K, Haapasalo J, Wang EY, De Antonellis P, Suzuki H, Farooq H, Balin P, Kharas K, Van Ommeren R, Sirbu O, Rastan A, Krumholtz SL, Ly M, Ahmadi M, Deblois G, Srikanthan D, Luu B, Loukides J, Wu X, Garzia L, Ramaswamy V, Kanshin E, Sánchez-Osuna M, El-Hamamy I, Coutinho FJ, Prinos P, Singh S, Donovan LK, Daniels C, Schramek D, Tyers M, Weiss S, Stein LD, Lupien M, Wouters BG, Garcia BA, Arrowsmith CH, Sorensen PH, Angers S, Jabado N, Dirks PB, Mack SC, Agnihotri S, Rich JN, Taylor MD. PMID: 32445698.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    57. Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation. J Exp Med. 2020 05 04; 217(5). Zhan X, Guo S, Li Y, Ran H, Huang H, Mi L, Wu J, Wang X, Xiao D, Chen L, Li D, Zhang S, Yan X, Yu Y, Li T, Han Q, He K, Cui J, Li T, Zhou T, Rich JN, Bao S, Zhang X, Li A, Man J. PMID: 32181805; PMCID: PMC7201922.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    58. Glioblastoma Stem Cells: Driving Resilience through Chaos. Trends Cancer. 2020 03; 6(3):223-235. Prager BC, Bhargava S, Mahadev V, Hubert CG, Rich JN. PMID: 32101725; PMCID: PMC8779821.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansCells
    59. Type I Interferon Regulates a Coordinated Gene Network to Enhance Cytotoxic T Cell-Mediated Tumor Killing. Cancer Discov. 2020 03; 10(3):382-393. Fan JB, Miyauchi S, Xu HZ, Liu D, Kim LJY, Burkart C, Cheng H, Arimoto KI, Yan M, Zhou Y, Gyorffy B, Knobeloch KP, Rich JN, Cang H, Fu XD, Zhang DE. PMID: 31974171; PMCID: PMC7058499.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    60. Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis. Cell Stem Cell. 2020 02 06; 26(2):187-204.e10. Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, Weis SM, Mack SC, Negraes PD, Trujillo CA, Penalva LO, Feng J, Lan Z, Zhang R, Wessel AW, Dhawan S, Diamond MS, Chen CC, Wechsler-Reya RJ, Gage FH, Hu H, Siqueira-Neto JL, Muotri AR, Cheresh DA, Rich JN. PMID: 31956038; PMCID: PMC9628766.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    61. Functional Enhancers Shape Extrachromosomal Oncogene Amplifications. Cell. 2019 11 27; 179(6):1330-1341.e13. Morton AR, Dogan-Artun N, Faber ZJ, MacLeod G, Bartels CF, Piazza MS, Allan KC, Mack SC, Wang X, Gimple RC, Wu Q, Rubin BP, Shetty S, Angers S, Dirks PB, Sallari RC, Lupien M, Rich JN, Scacheri PC. PMID: 31761532; PMCID: PMC7241652.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCells
    62. Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma. Cancer Res. 2019 10 15; 79(20):5218-5232. Jung J, Zhang Y, Celiku O, Zhang W, Song H, Williams BJ, Giles AJ, Rich JN, Abounader R, Gilbert MR, Park DM. PMID: 31488423; PMCID: PMC6801103.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    63. Treatment of glioblastoma using multicomponent silica nanoparticles. Adv Ther (Weinh). 2019 Nov; 2(11). Turan O, Bielecki PA, Perera V, Lorkowski M, Covarrubias G, Tong K, Yun A, Loutrianakis G, Raghunathan S, Park Y, Moon T, Cooley S, Dixit D, Griswold MA, Ghaghada KB, Peiris PM, Rich JN, Karathanasis E. PMID: 32953978; PMCID: PMC7500584.
      View in: PubMed   Mentions: 5  
    64. The dystroglycan receptor maintains glioma stem cells in the vascular niche. Acta Neuropathol. 2019 12; 138(6):1033-1052. Day BW, Lathia JD, Bruce ZC, D'Souza RCJ, Baumgartner U, Ensbey KS, Lim YC, Stringer BW, Akgül S, Offenhäuser C, Li Y, Jamieson PR, Smith FM, Jurd CLR, Robertson T, Inglis PL, Lwin Z, Jeffree RL, Johns TG, Bhat KPL, Rich JN, Campbell KP, Boyd AW. PMID: 31463571; PMCID: PMC6851226.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    65. Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock. Cancer Discov. 2019 11; 9(11):1556-1573. Dong Z, Zhang G, Qu M, Gimple RC, Wu Q, Qiu Z, Prager BC, Wang X, Kim LJY, Morton AR, Dixit D, Zhou W, Huang H, Li B, Zhu Z, Bao S, Mack SC, Chavez L, Kay SA, Rich JN. PMID: 31455674; PMCID: PMC6983300.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    66. Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells. Sci Transl Med. 2019 08 07; 11(504). Wang X, Yang K, Wu Q, Kim LJY, Morton AR, Gimple RC, Prager BC, Shi Y, Zhou W, Bhargava S, Zhu Z, Jiang L, Tao W, Qiu Z, Zhao L, Zhang G, Li X, Agnihotri S, Mischel PS, Mack SC, Bao S, Rich JN. PMID: 31391321; PMCID: PMC7568232.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    67. Challenges to curing primary brain tumours. Nat Rev Clin Oncol. 2019 08; 16(8):509-520. Aldape K, Brindle KM, Chesler L, Chopra R, Gajjar A, Gilbert MR, Gottardo N, Gutmann DH, Hargrave D, Holland EC, Jones DTW, Joyce JA, Kearns P, Kieran MW, Mellinghoff IK, Merchant M, Pfister SM, Pollard SM, Ramaswamy V, Rich JN, Robinson GW, Rowitch DH, Sampson JH, Taylor MD, Workman P, Gilbertson RJ. PMID: 30733593; PMCID: PMC6650350.
      View in: PubMed   Mentions: 242     Fields:    Translation:Humans
    68. Reply to 'Assembling the brain trust: the multidisciplinary imperative in neuro-oncology'. Nat Rev Clin Oncol. 2019 08; 16(8):522-523. Aldape K, Brindle KM, Chesler L, Chopra R, Gajjar A, Gilbert MR, Gottardo N, Gutmann DH, Hargrave D, Holland EC, Jones DTW, Joyce JA, Kearns P, Kieran MW, Mellinghoff IK, Merchant M, Pfister SM, Pollard SM, Ramaswamy V, Rich JN, Robinson GW, Rowitch DH, Sampson JH, Taylor MD, Workman P, Gilbertson RJ. PMID: 31150022.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    69. Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling. Cell Metab. 2019 09 03; 30(3):525-538.e8. Bi J, Ichu TA, Zanca C, Yang H, Zhang W, Gu Y, Chowdhry S, Reed A, Ikegami S, Turner KM, Zhang W, Villa GR, Wu S, Quehenberger O, Yong WH, Kornblum HI, Rich JN, Cloughesy TF, Cavenee WK, Furnari FB, Cravatt BF, Mischel PS. PMID: 31303424; PMCID: PMC6742496.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    70. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 2019 07 08; 36(1):51-67.e7. Sin-Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, Du Y, Lu M, Patel N, Torchia J, Popovski D, Fouladi M, Guilhamon P, Hansford JR, Leary S, Hoffman LM, Mulcahy Levy JM, Lassaletta A, Solano-Paez P, Rivas E, Reddy A, Gillespie GY, Gupta N, Van Meter TE, Nakamura H, Wong TT, Ra YS, Kim SK, Massimi L, Grundy RG, Fangusaro J, Johnston D, Chan J, Lafay-Cousin L, Hwang EI, Wang Y, Catchpoole D, Michaud J, Ellezam B, Ramanujachar R, Lindsay H, Taylor MD, Hawkins CE, Bouffet E, Jabado N, Singh SK, Kleinman CL, Barsyte-Lovejoy D, Li XN, Dirks PB, Lin CY, Mack SC, Rich JN, Huang A. PMID: 31287992.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    71. Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling. Cancer Discov. 2019 09; 9(9):1248-1267. Gimple RC, Kidwell RL, Kim LJY, Sun T, Gromovsky AD, Wu Q, Wolf M, Lv D, Bhargava S, Jiang L, Prager BC, Wang X, Ye Q, Zhu Z, Zhang G, Dong Z, Zhao L, Lee D, Bi J, Sloan AE, Mischel PS, Brown JM, Cang H, Huan T, Mack SC, Xie Q, Rich JN. PMID: 31201181; PMCID: PMC6785242.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    72. Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer. Genes Dev. 2019 06 01; 33(11-12):591-609. Gimple RC, Bhargava S, Dixit D, Rich JN. PMID: 31160393; PMCID: PMC6546059.
      View in: PubMed   Mentions: 152     Fields:    Translation:HumansAnimalsCells
    73. Impact on Health-Related Quality of Life of Induction Chemotherapy Compared With Concurrent Cisplatin and Radiation Therapy in Patients With Head and Neck Cancer. Clin Oncol (R Coll Radiol). 2019 09; 31(9):e123-e131. Adkins D, Ley J, Oppelt P, Gay HA, Daly M, Paniello RC, Jackson R, Pipkorn P, Rich J, Zevallos J, Trinkaus K, Thorstad W. PMID: 31147146.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    74. Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells. Viruses. 2019 04 20; 11(4). Bernatchez JA, Coste M, Beck S, Wells GA, Luna LA, Clark AE, Zhu Z, Hecht D, Rich JN, Sohl CD, Purse BW, Siqueira-Neto JL. PMID: 31010044; PMCID: PMC6521205.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    75. Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis. Cell Stem Cell. 2019 05 02; 24(5):707-723.e8. Weng Q, Wang J, Wang J, He D, Cheng Z, Zhang F, Verma R, Xu L, Dong X, Liao Y, He X, Potter A, Zhang L, Zhao C, Xin M, Zhou Q, Aronow BJ, Blackshear PJ, Rich JN, He Q, Zhou W, Suvà ML, Waclaw RR, Potter SS, Yu G, Lu QR. PMID: 30982771; PMCID: PMC6669001.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    76. Mechanism of Action of Methotrexate Against Zika Virus. Viruses. 2019 04 10; 11(4). Beck S, Zhu Z, Oliveira MF, Smith DM, Rich JN, Bernatchez JA, Siqueira-Neto JL. PMID: 30974762; PMCID: PMC6521145.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    77. Chromatin remodeler HELLS maintains glioma stem cells through E2F3 and MYC. JCI Insight. 2019 04 04; 4(7). Zhang G, Dong Z, Prager BC, Kim LJ, Wu Q, Gimple RC, Wang X, Bao S, Hamerlik P, Rich JN. PMID: 30779712; PMCID: PMC6483649.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    78. Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma. J Exp Med. 2019 05 06; 216(5):1071-1090. Mack SC, Singh I, Wang X, Hirsch R, Wu Q, Villagomez R, Bernatchez JA, Zhu Z, Gimple RC, Kim LJY, Morton A, Lai S, Qiu Z, Prager BC, Bertrand KC, Mah C, Zhou W, Lee C, Barnett GH, Vogelbaum MA, Sloan AE, Chavez L, Bao S, Scacheri PC, Siqueira-Neto JL, Lin CY, Rich JN. PMID: 30948495; PMCID: PMC6504206.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    79. SUFU: The Jekyll and Hyde of the Cerebellum. Dev Cell. 2019 01 28; 48(2):131-132. Kim LJY, Bhargava S, Gimple RC, Rich JN. PMID: 30695694.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    80. Cancer Stem Cells: The Architects of the Tumor Ecosystem. Cell Stem Cell. 2019 01 03; 24(1):41-53. Prager BC, Xie Q, Bao S, Rich JN. PMID: 30609398; PMCID: PMC6350931.
      View in: PubMed   Mentions: 196     Fields:    Translation:HumansAnimalsCells
    81. Poly(ADP-Ribose) Polymerase Inhibition Sensitizes Colorectal Cancer-Initiating Cells to Chemotherapy. Stem Cells. 2019 01; 37(1):42-53. Jarrar A, Lotti F, DeVecchio J, Ferrandon S, Gantt G, Mace A, Karagkounis G, Orloff M, Venere M, Hitomi M, Lathia J, Rich JN, Kalady MF. PMID: 30353615.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    82. N6-methyladenine DNA Modification in Glioblastoma. Cell. 2018 11 15; 175(5):1228-1243.e20. Xie Q, Wu TP, Gimple RC, Li Z, Prager BC, Wu Q, Yu Y, Wang P, Wang Y, Gorkin DU, Zhang C, Dowiak AV, Lin K, Zeng C, Sui Y, Kim LJY, Miller TE, Jiang L, Lee-Poturalski C, Huang Z, Fang X, Zhai K, Mack SC, Sander M, Bao S, Kerstetter-Fogle AE, Sloan AE, Xiao AZ, Rich JN. PMID: 30392959; PMCID: PMC6433469.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimalsCells
    83. Comparing costs of a senior wellness care redesign in group and independent physician practices of an accountable care organization. Int J Health Plann Manage. 2019 Jan; 34(1):241-250. Bustamante AV, Martinez A, Rich J, Chen X, Rodriguez HP. PMID: 30109902.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    84. Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE): A Cluster-Randomized Pragmatic Trial of a Multifactorial Fall Injury Prevention Strategy: Design and Methods. J Gerontol A Biol Sci Med Sci. 2018 07 09; 73(8):1053-1061. Bhasin S, Gill TM, Reuben DB, Latham NK, Gurwitz JH, Dykes P, McMahon S, Storer TW, Duncan PW, Ganz DA, Basaria S, Miller ME, Travison TG, Greene EJ, Dziura J, Esserman D, Allore H, Carnie MB, Fagan M, Hanson C, Baker D, Greenspan SL, Alexander N, Ko F, Siu AL, Volpi E, Wu AW, Rich J, Waring SC, Wallace R, Casteel C, Magaziner J, Charpentier P, Lu C, Araujo K, Rajeevan H, Margolis S, Eder R, McGloin JM, Skokos E, Wiggins J, Garber L, Clauser SB, Correa-De-Araujo R, Peduzzi P. PMID: 29045582; PMCID: PMC6037050.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    85. AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells. Cell Stem Cell. 2018 Jul 05; 23(1):86-100.e6. Pei S, Minhajuddin M, Adane B, Khan N, Stevens BM, Mack SC, Lai S, Rich JN, Inguva A, Shannon KM, Kim H, Tan AC, Myers JR, Ashton JM, Neff T, Pollyea DA, Smith CA, Jordan CT. PMID: 29910151; PMCID: PMC6035102.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    86. Ibrutinib inactivates BMX-STAT3 in glioma stem cells to impair malignant growth and radioresistance. Sci Transl Med. 2018 05 30; 10(443). Shi Y, Guryanova OA, Zhou W, Liu C, Huang Z, Fang X, Wang X, Chen C, Wu Q, He Z, Wang W, Zhang W, Jiang T, Liu Q, Chen Y, Wang W, Wu J, Kim L, Gimple RC, Feng H, Kung HF, Yu JS, Rich JN, Ping YF, Bian XW, Bao S. PMID: 29848664; PMCID: PMC6431250.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    87. Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression. Cell Stem Cell. 2018 04 05; 22(4):514-528.e5. Wang X, Prager BC, Wu Q, Kim LJY, Gimple RC, Shi Y, Yang K, Morton AR, Zhou W, Zhu Z, Obara EAA, Miller TE, Song A, Lai S, Hubert CG, Jin X, Huang Z, Fang X, Dixit D, Tao W, Zhai K, Chen C, Dong Z, Zhang G, Dombrowski SM, Hamerlik P, Mack SC, Bao S, Rich JN. PMID: 29625067; PMCID: PMC5947947.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    88. A posttranslational modification of the mitotic kinesin Eg5 that enhances its mechanochemical coupling and alters its mitotic function. Proc Natl Acad Sci U S A. 2018 02 20; 115(8):E1779-E1788. Muretta JM, Reddy BJN, Scarabelli G, Thompson AF, Jariwala S, Major J, Venere M, Rich JN, Willard B, Thomas DD, Stumpff J, Grant BJ, Gross SP, Rosenfeld SS. PMID: 29432173; PMCID: PMC5828613.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    89. Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling. Nature. 2018 01 04; 553(7686):101-105. Mack SC, Pajtler KW, Chavez L, Okonechnikov K, Bertrand KC, Wang X, Erkek S, Federation A, Song A, Lee C, Wang X, McDonald L, Morrow JJ, Saiakhova A, Sin-Chan P, Wu Q, Michaelraj KA, Miller TE, Hubert CG, Ryzhova M, Garzia L, Donovan L, Dombrowski S, Factor DC, Luu B, Valentim CLL, Gimple RC, Morton A, Kim L, Prager BC, Lee JJY, Wu X, Zuccaro J, Thompson Y, Holgado BL, Reimand J, Ke SQ, Tropper A, Lai S, Vijayarajah S, Doan S, Mahadev V, Miñan AF, Gröbner SN, Lienhard M, Zapatka M, Huang Z, Aldape KD, Carcaboso AM, Houghton PJ, Keir ST, Milde T, Witt H, Li Y, Li CJ, Bian XW, Jones DTW, Scott I, Singh SK, Huang A, Dirks PB, Bouffet E, Bradner JE, Ramaswamy V, Jabado N, Rutka JT, Northcott PA, Lupien M, Lichter P, Korshunov A, Scacheri PC, Pfister SM, Kool M, Taylor MD, Rich JN. PMID: 29258295; PMCID: PMC5993422.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    90. Inhibition of ID1-BMPR2 Intrinsic Signaling Sensitizes Glioma Stem Cells to Differentiation Therapy. Clin Cancer Res. 2018 01 15; 24(2):383-394. Jin X, Jin X, Kim LJY, Dixit D, Jeon HY, Kim EJ, Kim JK, Lee SY, Yin J, Rich JN, Kim H. PMID: 29208670.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    91. Constitutive Ras signaling and Ink4a/Arf inactivation cooperate during the development of B-ALL in mice. Blood Adv. 2017 Nov 28; 1(25):2361-2374. Sewastianik T, Jiang M, Sukhdeo K, Patel SS, Roberts K, Kang Y, Alduaij A, Dennis PS, Lawney B, Liu R, Song Z, Xiong J, Zhang Y, Lemieux ME, Pinkus GS, Rich JN, Weinstock DM, Mullighan CG, Sharpless NE, Carrasco RD. PMID: 29296886; PMCID: PMC5729631.
      View in: PubMed   Mentions: 6     Fields:    
    92. Targeting Glioma Stem Cell-Derived Pericytes Disrupts the Blood-Tumor Barrier and Improves Chemotherapeutic Efficacy. Cell Stem Cell. 2017 Nov 02; 21(5):591-603.e4. Zhou W, Chen C, Shi Y, Wu Q, Gimple RC, Fang X, Huang Z, Zhai K, Ke SQ, Ping YF, Feng H, Rich JN, Yu JS, Bao S, Bian XW. PMID: 29100012; PMCID: PMC5687837.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    93. Targeting glioma stem cells through combined BMI1 and EZH2 inhibition. Nat Med. 2017 Nov; 23(11):1352-1361. Jin X, Kim LJY, Wu Q, Wallace LC, Prager BC, Sanvoranart T, Gimple RC, Wang X, Mack SC, Miller TE, Huang P, Valentim CL, Zhou QG, Barnholtz-Sloan JS, Bao S, Sloan AE, Rich JN. PMID: 29035367; PMCID: PMC5679732.
      View in: PubMed   Mentions: 150     Fields:    Translation:HumansAnimalsCells
    94. New Advances and Challenges of Targeting Cancer Stem Cells. Cancer Res. 2017 10 01; 77(19):5222-5227. Dashzeveg NK, Taftaf R, Ramos EK, Torre-Healy L, Chumakova A, Silver DJ, Alban TJ, Sinyuk M, Thiagarajan PS, Jarrar AM, Turaga SM, Saygin C, Mulkearns-Hubert E, Hitomi M, Rich JN, Gerson SL, Lathia JD, Liu H. PMID: 28928129; PMCID: PMC5833988.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    95. Correction: Zika virus has oncolytic activity against glioblastoma stem cells. J Exp Med. 2017 10 02; 214(10):3145. Zhu Z, Gorman MJ, McKenzie LD, Chai JN, Hubert CG, Prager BC, Fernandez E, Richner JM, Zhang R, Shan C, Tycksen E, Wang X, Shi PY, Diamond MS, Rich JN, Chheda MG. PMID: 28916645; PMCID: PMC5626409.
      View in: PubMed   Mentions: 7     Fields:    
    96. Zika virus has oncolytic activity against glioblastoma stem cells. J Exp Med. 2017 Oct 02; 214(10):2843-2857. Zhu Z, Gorman MJ, McKenzie LD, Chai JN, Hubert CG, Prager BC, Fernandez E, Richner JM, Zhang R, Shan C, Tycksen E, Wang X, Shi PY, Diamond MS, Rich JN, Chheda MG. PMID: 28874392; PMCID: PMC5626408.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    97. Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value. PLoS One. 2017; 12(8):e0182954. Rosager AM, Sørensen MD, Dahlrot RH, Hansen S, Schonberg DL, Rich JN, Lathia JD, Kristensen BW. PMID: 28837569; PMCID: PMC5570299.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    98. MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor-Initiating Cells. Cancer Res. 2017 09 15; 77(18):4947-4960. Wang X, Huang Z, Wu Q, Prager BC, Mack SC, Yang K, Kim LJY, Gimple RC, Shi Y, Lai S, Xie Q, Miller TE, Hubert CG, Song A, Dong Z, Zhou W, Fang X, Zhu Z, Mahadev V, Bao S, Rich JN. PMID: 28729418; PMCID: PMC5600855.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    99. One-pot synthesis of nanochain particles for targeting brain tumors. Nanoscale. 2017 Jul 13; 9(27):9659-9667. Perera VS, Covarrubias G, Lorkowski M, Atukorale P, Rao A, Raghunathan S, Gopalakrishnan R, Erokwu BO, Liu Y, Dixit D, Brady-Kalnay SM, Wilson D, Flask C, Rich J, Peiris PM, Karathanasis E. PMID: 28675230; PMCID: PMC5557407.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    100. Transcription elongation factors represent in vivo cancer dependencies in glioblastoma. Nature. 2017 07 20; 547(7663):355-359. Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu Q, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, Thummalapalli R, Hemann MT, Paddison PJ, Horbinski CM, Zuber J, Scacheri PC, Bernstein BE, Tesar PJ, Rich JN. PMID: 28678782; PMCID: PMC5896562.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    101. Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth. Nat Commun. 2017 06 01; 8:15080. Shi Y, Ping YF, Zhou W, He ZC, Chen C, Bian BS, Zhang L, Chen L, Lan X, Zhang XC, Zhou K, Liu Q, Long H, Fu TW, Zhang XN, Cao MF, Huang Z, Fang X, Wang X, Feng H, Yao XH, Yu SC, Cui YH, Zhang X, Rich JN, Bao S, Bian XW. PMID: 28569747; PMCID: PMC5461490.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansAnimalsCells
    102. Nicotinamide metabolism regulates glioblastoma stem cell maintenance. JCI Insight. 2017 May 18; 2(10). Jung J, Kim LJ, Wang X, Wu Q, Sanvoranart T, Hubert CG, Prager BC, Wallace LC, Jin X, Mack SC, Rich JN. PMID: 28515364; PMCID: PMC5436539.
      View in: PubMed   Mentions: 49     Fields:    
    103. The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking. Oncotarget. 2017 May 16; 8(20):33316-33328. Soeda A, Lathia J, Williams BJ, Wu Q, Gallagher J, Androutsellis-Theotokis A, Giles AJ, Yang C, Zhuang Z, Gilbert MR, Rich JN, Park DM. PMID: 28410196; PMCID: PMC5464870.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    104. Messenger RNA Methylation Regulates Glioblastoma Tumorigenesis. Cancer Cell. 2017 04 10; 31(4):474-475. Dixit D, Xie Q, Rich JN, Zhao JC. PMID: 28399407; PMCID: PMC6482444.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    105. Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events. Neuro Oncol. 2017 04 01; 19(4):503-513. Ayuso JM, Monge R, Martínez-González A, Virumbrales-Muñoz M, Llamazares GA, Berganzo J, Hernández-Laín A, Santolaria J, Doblaré M, Hubert C, Rich JN, Sánchez-Gómez P, Pérez-García VM, Ochoa I, Fernández LJ. PMID: 28062831; PMCID: PMC5464359.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    106. Purine synthesis promotes maintenance of brain tumor initiating cells in glioma. Nat Neurosci. 2017 May; 20(5):661-673. Wang X, Yang K, Xie Q, Wu Q, Mack SC, Shi Y, Kim LJY, Prager BC, Flavahan WA, Liu X, Singer M, Hubert CG, Miller TE, Zhou W, Huang Z, Fang X, Regev A, Suvà ML, Hwang TH, Locasale JW, Bao S, Rich JN. PMID: 28346452; PMCID: PMC6015494.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    107. A Multilevel Analysis of Patient Engagement and Patient-Reported Outcomes in Primary Care Practices of Accountable Care Organizations. J Gen Intern Med. 2017 Jun; 32(6):640-647. Shortell SM, Poon BY, Ramsay PP, Rodriguez HP, Ivey SL, Huber T, Rich J, Summerfelt T. PMID: 28160187; PMCID: PMC5442008.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    108. Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance. Cell Stem Cell. 2017 02 02; 20(2):233-246.e7. Liau BB, Sievers C, Donohue LK, Gillespie SM, Flavahan WA, Miller TE, Venteicher AS, Hebert CH, Carey CD, Rodig SJ, Shareef SJ, Najm FJ, van Galen P, Wakimoto H, Cahill DP, Rich JN, Aster JC, Suvà ML, Patel AP, Bernstein BE. PMID: 27989769; PMCID: PMC5291795.
      View in: PubMed   Mentions: 190     Fields:    Translation:HumansCells
    109. Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination. J Exp Med. 2017 01; 214(1):245-267. Fang X, Zhou W, Wu Q, Huang Z, Shi Y, Yang K, Chen C, Xie Q, Mack SC, Wang X, Carcaboso AM, Sloan AE, Ouyang G, McLendon RE, Bian XW, Rich JN, Bao S. PMID: 27923907; PMCID: PMC5206492.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    110. Tetraspanin CD9 stabilizes gp130 by preventing its ubiquitin-dependent lysosomal degradation to promote STAT3 activation in glioma stem cells. Cell Death Differ. 2017 01; 24(1):167-180. Shi Y, Zhou W, Cheng L, Chen C, Huang Z, Fang X, Wu Q, He Z, Xu S, Lathia JD, Ping Y, Rich JN, Bian XW, Bao S. PMID: 27740621; PMCID: PMC5260495.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    111. Cancer stem cells: understanding tumor hierarchy and heterogeneity. Medicine (Baltimore). 2016 Sep; 95(1 Suppl 1):S2-S7. Rich JN. PMID: 27611934; PMCID: PMC5599210.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansCells
    112. Cancer stem cells: A nuanced perspective. Medicine (Baltimore). 2016 Sep; 95(1 Suppl 1):S26-S28. Rich JN, Matsui WH, Chang JC. PMID: 27611936; PMCID: PMC5599213.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    113. Cancer stem cells: master gatekeepers and regulators of cancer growth and metastasis Introduction. Medicine (Baltimore). 2016 Sep; 95(1 Suppl 1):S1. Rich JN. PMID: 27611933; PMCID: PMC5599209.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    114. The ID1-CULLIN3 Axis Regulates Intracellular SHH and WNT Signaling in Glioblastoma Stem Cells. Cell Rep. 2016 08 09; 16(6):1629-1641. Jin X, Jeon HM, Jin X, Kim EJ, Yin J, Jeon HY, Sohn YW, Oh SY, Kim JK, Kim SH, Jung JE, Kwak S, Tang KF, Xu Y, Rich JN, Kim H. PMID: 27477274.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    115. Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells. Oncotarget. 2016 Jul 12; 7(28):43852-43867. Burgett ME, Lathia JD, Roth P, Nowacki AS, Galileo DS, Pugacheva E, Huang P, Vasanji A, Li M, Byzova T, Mikkelsen T, Bao S, Rich JN, Weller M, Gladson CL. PMID: 27270311; PMCID: PMC5190064.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    116. RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation. J Clin Invest. 2016 07 01; 126(7):2757-72. Xie Q, Wu Q, Kim L, Miller TE, Liau BB, Mack SC, Yang K, Factor DC, Fang X, Huang Z, Zhou W, Alazem K, Wang X, Bernstein BE, Bao S, Rich JN. PMID: 27322055; PMCID: PMC4922685.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    117. Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion. Stem Cells. 2016 08; 34(8):2026-39. Otvos B, Silver DJ, Mulkearns-Hubert EE, Alvarado AG, Turaga SM, Sorensen MD, Rayman P, Flavahan WA, Hale JS, Stoltz K, Sinyuk M, Wu Q, Jarrar A, Kim SH, Fox PL, Nakano I, Rich JN, Ransohoff RM, Finke J, Kristensen BW, Vogelbaum MA, Lathia JD. PMID: 27145382; PMCID: PMC5820763.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    118. Chromosomal Instability Affects the Tumorigenicity of Glioblastoma Tumor-Initiating Cells. Cancer Discov. 2016 05; 6(5):532-45. Godek KM, Venere M, Wu Q, Mills KD, Hickey WF, Rich JN, Compton DA. PMID: 27001151; PMCID: PMC4854766.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    119. Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models. Cancer Res. 2016 04 15; 76(8):2432-42. Dermawan JK, Hitomi M, Silver DJ, Wu Q, Sandlesh P, Sloan AE, Purmal AA, Gurova KV, Rich JN, Lathia JD, Stark GR, Venere M. PMID: 26921329; PMCID: PMC4873320.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    120. A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo. Cancer Res. 2016 04 15; 76(8):2465-77. Hubert CG, Rivera M, Spangler LC, Wu Q, Mack SC, Prager BC, Couce M, McLendon RE, Sloan AE, Rich JN. PMID: 26896279; PMCID: PMC4873351.
      View in: PubMed   Mentions: 232     Fields:    Translation:HumansAnimalsCells
    121. An epigenetic gateway to brain tumor cell identity. Nat Neurosci. 2016 Jan; 19(1):10-9. Mack SC, Hubert CG, Miller TE, Taylor MD, Rich JN. PMID: 26713744; PMCID: PMC5568053.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    122. MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin. Cancer Cell. 2015 Dec 14; 28(6):715-729. Gallo M, Coutinho FJ, Vanner RJ, Gayden T, Mack SC, Murison A, Remke M, Li R, Takayama N, Desai K, Lee L, Lan X, Park NI, Barsyte-Lovejoy D, Smil D, Sturm D, Kushida MM, Head R, Cusimano MD, Bernstein M, Clarke ID, Dick JE, Pfister SM, Rich JN, Arrowsmith CH, Taylor MD, Jabado N, Bazett-Jones DP, Lupien M, Dirks PB. PMID: 26626085.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    123. Lending an 'ELPing hand to tumor initiation. J Exp Med. 2015 Nov 16; 212(12):1989. Rich J. PMID: 26573584; PMCID: PMC4647271.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    124. Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth. Oncotarget. 2015 Nov 10; 6(35):37300-15. Zhou W, Cheng L, Shi Y, Ke SQ, Huang Z, Fang X, Chu CW, Xie Q, Bian XW, Rich JN, Bao S. PMID: 26510911; PMCID: PMC4741931.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    125. Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells. Cancer Cell. 2015 Oct 12; 28(4):441-455. Schonberg DL, Miller TE, Wu Q, Flavahan WA, Das NK, Hale JS, Hubert CG, Mack SC, Jarrar AM, Karl RT, Rosager AM, Nixon AM, Tesar PJ, Hamerlik P, Kristensen BW, Horbinski C, Connor JR, Fox PL, Lathia JD, Rich JN. PMID: 26461092; PMCID: PMC4646058.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansAnimalsCells
    126. "PEAR-ing" Genomic and Epigenomic Analyses for Cancer Gene Discovery. Cancer Discov. 2015 Oct; 5(10):1018-20. Mack SC, Rich JN, Scacheri PC. PMID: 26429935; PMCID: PMC4608252.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    127. Coordination of self-renewal in glioblastoma by integration of adhesion and microRNA signaling. Neuro Oncol. 2016 05; 18(5):656-66. Alvarado AG, Turaga SM, Sathyan P, Mulkearns-Hubert EE, Otvos B, Silver DJ, Hale JS, Flavahan WA, Zinn PO, Sinyuk M, Li M, Guda MR, Velpula KK, Tsung AJ, Nakano I, Vogelbaum MA, Majumder S, Rich JN, Lathia JD. PMID: 26374689; PMCID: PMC4827035.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    128. The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma. Sci Transl Med. 2015 Sep 09; 7(304):304ra143. Venere M, Horbinski C, Crish JF, Jin X, Vasanji A, Major J, Burrows AC, Chang C, Prokop J, Wu Q, Sims PA, Canoll P, Summers MK, Rosenfeld SS, Rich JN. PMID: 26355032; PMCID: PMC4743764.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    129. ZNF555 protein binds to transcriptional activator site of 4qA allele and ANT1: potential implication in Facioscapulohumeral dystrophy. Nucleic Acids Res. 2015 Sep 30; 43(17):8227-42. Kim E, Rich J, Karoutas A, Tarlykov P, Cochet E, Malysheva D, Mamchaoui K, Ogryzko V, Pirozhkova I. PMID: 26184877; PMCID: PMC4787827.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    130. Cancer stem cells in glioblastoma. Genes Dev. 2015 Jun 15; 29(12):1203-17. Lathia JD, Mack SC, Mulkearns-Hubert EE, Valentim CL, Rich JN. PMID: 26109046; PMCID: PMC4495393.
      View in: PubMed   Mentions: 687     Fields:    Translation:HumansAnimalsCells
    131. CDC20 maintains tumor initiating cells. Oncotarget. 2015 May 30; 6(15):13241-54. Xie Q, Wu Q, Mack SC, Yang K, Kim L, Hubert CG, Flavahan WA, Chu C, Bao S, Rich JN. PMID: 25938542; PMCID: PMC4537011.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    132. Growth Factor Receptor Fusions Predict Therapeutic Sensitivity. Clin Cancer Res. 2015 Jul 15; 21(14):3105-7. Ahluwalia MS, Rich JN. PMID: 25995339.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    133. Development of a Fluorescent Reporter System to Delineate Cancer Stem Cells in Triple-Negative Breast Cancer. Stem Cells. 2015 Jul; 33(7):2114-2125. Thiagarajan PS, Hitomi M, Hale JS, Alvarado AG, Otvos B, Sinyuk M, Stoltz K, Wiechert A, Mulkearns-Hubert E, Jarrar A, Zheng Q, Thomas D, Egelhoff T, Rich JN, Liu H, Lathia JD, Reizes O. PMID: 25827713; PMCID: PMC4494654.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    134. Differential connexin function enhances self-renewal in glioblastoma. Cell Rep. 2015 May 19; 11(7):1031-42. Hitomi M, Deleyrolle LP, Mulkearns-Hubert EE, Jarrar A, Li M, Sinyuk M, Otvos B, Brunet S, Flavahan WA, Hubert CG, Goan W, Hale JS, Alvarado AG, Zhang A, Rohaus M, Oli M, Vedam-Mai V, Fortin JM, Futch HS, Griffith B, Wu Q, Xia CH, Gong X, Ahluwalia MS, Rich JN, Reynolds BA, Lathia JD. PMID: 25959821; PMCID: PMC4502443.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    135. Feedback circuitry between miR-218 repression and RTK activation in glioblastoma. Sci Signal. 2015 May 05; 8(375):ra42. Mathew LK, Huangyang P, Mucaj V, Lee SS, Skuli N, Eisinger-Mathason TS, Biju K, Li B, Venneti S, Lal P, Lathia JD, Rich JN, Keith B, Simon MC. PMID: 25943352; PMCID: PMC4437515.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    136. Acquisition of meiotic DNA repair regulators maintain genome stability in glioblastoma. Cell Death Dis. 2015 Apr 23; 6:e1732. Rivera M, Wu Q, Hamerlik P, Hjelmeland AB, Bao S, Rich JN. PMID: 25906155; PMCID: PMC4650544.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    137. Mitochondrial control by DRP1 in brain tumor initiating cells. Nat Neurosci. 2015 Apr; 18(4):501-10. Xie Q, Wu Q, Horbinski CM, Flavahan WA, Yang K, Zhou W, Dombrowski SM, Huang Z, Fang X, Shi Y, Ferguson AN, Kashatus DF, Bao S, Rich JN. PMID: 25730670; PMCID: PMC4376639.
      View in: PubMed   Mentions: 181     Fields:    Translation:HumansCells
    138. Hyperthermia Sensitizes Glioma Stem-like Cells to Radiation by Inhibiting AKT Signaling. Cancer Res. 2015 Apr 15; 75(8):1760-9. Man J, Shoemake JD, Ma T, Rizzo AE, Godley AR, Wu Q, Mohammadi AM, Bao S, Rich JN, Yu JS. PMID: 25712125; PMCID: PMC4401644.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    139. Postoperative nausea and vomiting following orthognathic surgery. Int J Oral Maxillofac Surg. 2015 Jun; 44(6):745-51. Phillips C, Brookes CD, Rich J, Arbon J, Turvey TA. PMID: 25655765; PMCID: PMC4430405.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    140. Cancer stem cells: targeting the roots of cancer, seeds of metastasis, and sources of therapy resistance. Cancer Res. 2015 Mar 15; 75(6):924-9. Adorno-Cruz V, Kibria G, Liu X, Doherty M, Junk DJ, Guan D, Hubert C, Venere M, Mulkearns-Hubert E, Sinyuk M, Alvarado A, Caplan AI, Rich J, Gerson SL, Lathia J, Liu H. PMID: 25604264; PMCID: PMC4359955.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    141. Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth. Nat Cell Biol. 2015 Feb; 17(2):170-82. Zhou W, Ke SQ, Huang Z, Flavahan W, Fang X, Paul J, Wu L, Sloan AE, McLendon RE, Li X, Rich JN, Bao S. PMID: 25580734; PMCID: PMC4312504.
      View in: PubMed   Mentions: 395     Fields:    Translation:HumansAnimalsCells
    142. Lgr5 Marks Post-Mitotic, Lineage Restricted Cerebellar Granule Neurons during Postnatal Development. PLoS One. 2014; 9(12):e114433. Miller TE, Wang J, Sukhdeo K, Horbinski C, Tesar PJ, Wechsler-Reya RJ, Rich JN. PMID: 25493560; PMCID: PMC4262395.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    143. Fidelity of implementation to a care team redesign and improved outcomes of diabetes care. Int J Qual Health Care. 2015 Feb; 27(1):60-6. Grace SM, Rich J, Chin W, Rodriguez HP. PMID: 25431469.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    144. Development of a Sox2 reporter system modeling cellular heterogeneity in glioma. Neuro Oncol. 2015 Mar; 17(3):361-71. Stoltz K, Sinyuk M, Hale JS, Wu Q, Otvos B, Walker K, Vasanji A, Rich JN, Hjelmeland AB, Lathia JD. PMID: 25416826; PMCID: PMC4483103.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    145. Sema3C promotes the survival and tumorigenicity of glioma stem cells through Rac1 activation. Cell Rep. 2014 Dec 11; 9(5):1812-1826. Man J, Shoemake J, Zhou W, Fang X, Wu Q, Rizzo A, Prayson R, Bao S, Rich JN, Yu JS. PMID: 25464848; PMCID: PMC4268066.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    146. The tailless root of glioma: cancer stem cells. Cell Stem Cell. 2014 Aug 07; 15(2):114-6. Xie Q, Flavahan WA, Bao S, Rich J. PMID: 25105574; PMCID: PMC4239656.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    147. The zinc finger transcription factor ZFX is required for maintaining the tumorigenic potential of glioblastoma stem cells. Stem Cells. 2014 Aug; 32(8):2033-47. Fang X, Huang Z, Zhou W, Wu Q, Sloan AE, Ouyang G, McLendon RE, Yu JS, Rich JN, Bao S. PMID: 24831540; PMCID: PMC4349564.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    148. Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression. Stem Cells. 2014 Jul; 32(7):1746-58. Hale JS, Otvos B, Sinyuk M, Alvarado AG, Hitomi M, Stoltz K, Wu Q, Flavahan W, Levison B, Johansen ML, Schmitt D, Neltner JM, Huang P, Ren B, Sloan AE, Silverstein RL, Gladson CL, DiDonato JA, Brown JM, McIntyre T, Hazen SL, Horbinski C, Rich JN, Lathia JD. PMID: 24737733; PMCID: PMC4063873.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    149. Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells. Glia. 2014 Oct; 62(10):1687-98. Bai Y, Lathia JD, Zhang P, Flavahan W, Rich JN, Mattson MP. PMID: 24909307; PMCID: PMC4141001.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    150. Role of cysteine-rich 61 protein (CCN1) in macrophage-mediated oncolytic herpes simplex virus clearance. Mol Ther. 2014 Sep; 22(9):1678-87. Thorne AH, Meisen WH, Russell L, Yoo JY, Bolyard CM, Lathia JD, Rich J, Puduvalli VK, Mao H, Yu J, Caligiuri MA, Tridandapani S, Kaur B. PMID: 24895995; PMCID: PMC4435480.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    151. Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression. J Clin Invest. 2014 Jul; 124(7):2861-76. Ferrarese R, Harsh GR, Yadav AK, Bug E, Maticzka D, Reichardt W, Dombrowski SM, Miller TE, Masilamani AP, Dai F, Kim H, Hadler M, Scholtens DM, Yu IL, Beck J, Srinivasasainagendra V, Costa F, Baxan N, Pfeifer D, von Elverfeldt D, Backofen R, Weyerbrock A, Duarte CW, He X, Prinz M, Chandler JP, Vogel H, Chakravarti A, Rich JN, Carro MS, Bredel M. PMID: 24865424; PMCID: PMC4071411.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    152. Phage display discovery of novel molecular targets in glioblastoma-initiating cells. Cell Death Differ. 2014 Aug; 21(8):1325-39. Liu JK, Lubelski D, Schonberg DL, Wu Q, Hale JS, Flavahan WA, Mulkearns-Hubert EE, Man J, Hjelmeland AB, Yu J, Lathia JD, Rich JN. PMID: 24832468; PMCID: PMC4085538.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    153. Systematic review of preoperative mandibular canal position as it relates to postoperative neurosensory disturbance following the sagittal split ramus osteotomy. Int J Oral Maxillofac Surg. 2014 Sep; 43(9):1076-81. Rich J, Golden BA, Phillips C. PMID: 24837554; PMCID: PMC4130761.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    154. Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy. Genes Dev. 2014 May 15; 28(10):1085-100. Yan K, Wu Q, Yan DH, Lee CH, Rahim N, Tritschler I, DeVecchio J, Kalady MF, Hjelmeland AB, Rich JN. PMID: 24788093; PMCID: PMC4035537.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    155. Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through HIF-1α accumulation. Nat Cell Biol. 2014 May; 16(5):445-56. Fan Y, Potdar AA, Gong Y, Eswarappa SM, Donnola S, Lathia JD, Hambardzumyan D, Rich JN, Fox PL. PMID: 24747440; PMCID: PMC4036069.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    156. EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties. Oncogene. 2015 Jan 29; 34(5):558-67. Miao H, Gale NW, Guo H, Qian J, Petty A, Kaspar J, Murphy AJ, Valenzuela DM, Yancopoulos G, Hambardzumyan D, Lathia JD, Rich JN, Lee J, Wang B. PMID: 24488013; PMCID: PMC4119862.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    157. High-Speed Coherent Raman Fingerprint Imaging of Biological Tissues. Nat Photonics. 2014; 8:627-634. Camp CH, Lee YJ, Heddleston JM, Hartshorn CM, Hight Walker AR, Rich JN, Lathia JD, Cicerone MT. PMID: 25621002; PMCID: PMC4304702.
      View in: PubMed   Mentions: 87  
    158. High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor. Cell Rep. 2014 Jan 16; 6(1):117-29. Lathia JD, Li M, Sinyuk M, Alvarado AG, Flavahan WA, Stoltz K, Rosager AM, Hale J, Hitomi M, Gallagher J, Wu Q, Martin J, Vidal JG, Nakano I, Dahlrot RH, Hansen S, McLendon RE, Sloan AE, Bao S, Hjelmeland AB, Carson CT, Naik UP, Kristensen B, Rich JN. PMID: 24373972; PMCID: PMC3899718.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    159. miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):291-6. Mathew LK, Skuli N, Mucaj V, Lee SS, Zinn PO, Sathyan P, Imtiyaz HZ, Zhang Z, Davuluri RV, Rao S, Venneti S, Lal P, Lathia JD, Rich JN, Keith B, Minn AJ, Simon MC. PMID: 24368849; PMCID: PMC3890843.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    160. Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A. J Exp Med. 2013 Dec 16; 210(13):2851-72. Lotti F, Jarrar AM, Pai RK, Hitomi M, Lathia J, Mace A, Gantt GA, Sukhdeo K, DeVecchio J, Vasanji A, Leahy P, Hjelmeland AB, Kalady MF, Rich JN. PMID: 24323355; PMCID: PMC3865474.
      View in: PubMed   Mentions: 167     Fields:    Translation:HumansAnimalsCells
    161. The evolving landscape of glioblastoma stem cells. Curr Opin Neurol. 2013 Dec; 26(6):701-7. Yan K, Yang K, Rich JN. PMID: 24152818; PMCID: PMC4031658.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    162. The Lgr5 transgene is expressed specifically in glycinergic amacrine cells in the mouse retina. Exp Eye Res. 2014 Feb; 119:106-10. Sukhdeo K, Koch CE, Miller TE, Zhou H, Rivera M, Yan K, Cepko CL, Lathia JD, Rich JN. PMID: 24246263; PMCID: PMC3986349.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    163. Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells. Endocr Relat Cancer. 2013 Dec; 20(6):797-808. Zheng Q, Banaszak L, Fracci S, Basali D, Dunlap SM, Hursting SD, Rich JN, Hjlemeland AB, Vasanji A, Berger NA, Lathia JD, Reizes O. PMID: 24025407; PMCID: PMC3843956.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    164. Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cells. Cell Death Differ. 2014 Feb; 21(2):258-69. Venere M, Hamerlik P, Wu Q, Rasmussen RD, Song LA, Vasanji A, Tenley N, Flavahan WA, Hjelmeland AB, Bartek J, Rich JN. PMID: 24121277; PMCID: PMC3890948.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    165. Genomics informs glioblastoma biology. Nat Genet. 2013 Oct; 45(10):1105-7. Schonberg DL, Bao S, Rich JN. PMID: 24071842.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    166. Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake. Nat Neurosci. 2013 Oct; 16(10):1373-82. Flavahan WA, Wu Q, Hitomi M, Rahim N, Kim Y, Sloan AE, Weil RJ, Nakano I, Sarkaria JN, Stringer BW, Day BW, Li M, Lathia JD, Rich JN, Hjelmeland AB. PMID: 23995067; PMCID: PMC3930177.
      View in: PubMed   Mentions: 229     Fields:    Translation:HumansAnimalsCells
    167. Changing the fate of cancer, one splice at a time. Proc Natl Acad Sci U S A. 2013 Sep 03; 110(36):14510-1. Schonberg DL, Venere M, Rich JN. PMID: 23969832; PMCID: PMC3767506.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    168. Tumor cells upregulate normoxic HIF-1α in response to doxorubicin. Cancer Res. 2013 Oct 15; 73(20):6230-42. Cao Y, Eble JM, Moon E, Yuan H, Weitzel DH, Landon CD, Nien CY, Hanna G, Rich JN, Provenzale JM, Dewhirst MW. PMID: 23959856; PMCID: PMC3800255.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    169. Cadherin-11 regulates motility in normal cortical neural precursors and glioblastoma. PLoS One. 2013; 8(8):e70962. Schulte JD, Srikanth M, Das S, Zhang J, Lathia JD, Yin L, Rich JN, Olson EC, Kessler JA, Chenn A. PMID: 23951053; PMCID: PMC3737231.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    170. Lyn facilitates glioblastoma cell survival under conditions of nutrient deprivation by promoting autophagy. PLoS One. 2013; 8(8):e70804. Liu WM, Huang P, Kar N, Burgett M, Muller-Greven G, Nowacki AS, Distelhorst CW, Lathia JD, Rich JN, Kappes JC, Gladson CL. PMID: 23936469; PMCID: PMC3732228.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    171. Brain tumor stem cells: Molecular characteristics and their impact on therapy. Mol Aspects Med. 2014 Oct; 39:82-101. Schonberg DL, Lubelski D, Miller TE, Rich JN. PMID: 23831316; PMCID: PMC3866208.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    172. Decoding the cancer stem cell hypothesis in glioblastoma. CNS Oncol. 2013 Jul; 2(4):319-30. Hale JS, Sinyuk M, Rich JN, Lathia JD. PMID: 24379973; PMCID: PMC3873749.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    173. Aptamer identification of brain tumor-initiating cells. Cancer Res. 2013 Aug 01; 73(15):4923-36. Kim Y, Wu Q, Hamerlik P, Hitomi M, Sloan AE, Barnett GH, Weil RJ, Leahy P, Hjelmeland AB, Rich JN. PMID: 23796560; PMCID: PMC3933790.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    174. Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells. Cancer Cell. 2013 Jun 10; 23(6):839-52. Kim E, Kim M, Woo DH, Shin Y, Shin J, Chang N, Oh YT, Kim H, Rheey J, Nakano I, Lee C, Joo KM, Rich JN, Nam DH, Lee J. PMID: 23684459; PMCID: PMC4109796.
      View in: PubMed   Mentions: 380     Fields:    Translation:HumansAnimalsCells
    175. Tax-interacting protein 1 coordinates the spatiotemporal activation of Rho GTPases and regulates the infiltrative growth of human glioblastoma. Oncogene. 2014 Mar 20; 33(12):1558-69. Wang H, Han M, Whetsell W, Wang J, Rich J, Hallahan D, Han Z. PMID: 23563176; PMCID: PMC3965267.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    176. Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth. Cell. 2013 Mar 28; 153(1):139-52. Cheng L, Huang Z, Zhou W, Wu Q, Donnola S, Liu JK, Fang X, Sloan AE, Mao Y, Lathia JD, Min W, McLendon RE, Rich JN, Bao S. PMID: 23540695; PMCID: PMC3638263.
      View in: PubMed   Mentions: 388     Fields:    Translation:HumansAnimalsCells
    177. β-Catenin/POU5F1/SOX2 transcription factor complex mediates IGF-I receptor signaling and predicts poor prognosis in lung adenocarcinoma. Cancer Res. 2013 May 15; 73(10):3181-9. Xu C, Xie D, Yu SC, Yang XJ, He LR, Yang J, Ping YF, Wang B, Yang L, Xu SL, Cui W, Wang QL, Fu WJ, Liu Q, Qian C, Cui YH, Rich JN, Kung HF, Zhang X, Bian XW. PMID: 23539445.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    178. Growth factor receptors define cancer hierarchies. Cancer Cell. 2013 Feb 11; 23(2):135-7. Venere M, Lathia JD, Rich JN. PMID: 23410969; PMCID: PMC3616317.
      View in: PubMed   Mentions: 4     Fields:    
    179. Mitotic control of cancer stem cells. Cancer Discov. 2013 Feb; 3(2):141-4. Venere M, Miller TE, Rich JN. PMID: 23400473; PMCID: PMC3616319.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    180. Multiplex flow cytometry barcoding and antibody arrays identify surface antigen profiles of primary and metastatic colon cancer cell lines. PLoS One. 2013; 8(1):e53015. Sukhdeo K, Paramban RI, Vidal JG, Elia J, Martin J, Rivera M, Carrasco DR, Jarrar A, Kalady MF, Carson CT, Balderas R, Hjelmeland AB, Lathia JD, Rich JN. PMID: 23308131; PMCID: PMC3538639.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    181. Laminin alpha 2 enables glioblastoma stem cell growth. Ann Neurol. 2012 Nov; 72(5):766-78. Lathia JD, Li M, Hall PE, Gallagher J, Hale JS, Wu Q, Venere M, Levy E, Rani MR, Huang P, Bae E, Selfridge J, Cheng L, Guvenc H, McLendon RE, Nakano I, Sloan AE, Phillips HS, Lai A, Gladson CL, Bredel M, Bao S, Hjelmeland AB, Rich JN. PMID: 23280793; PMCID: PMC3615417.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansCells
    182. Bevacizumab continuation beyond initial bevacizumab progression among recurrent glioblastoma patients. Br J Cancer. 2012 Oct 23; 107(9):1481-7. Reardon DA, Herndon JE, Peters KB, Desjardins A, Coan A, Lou E, Sumrall AL, Turner S, Lipp ES, Sathornsumetee S, Rich JN, Sampson JH, Friedman AH, Boulton ST, Bigner DD, Friedman HS, Vredenburgh JJ. PMID: 23037712; PMCID: PMC3493761.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCTClinical Trials
    183. Looking in the miR-ror: TGF-β-mediated activation of NF-κB in glioma. J Clin Invest. 2012 Oct; 122(10):3473-5. Eyler CE, Rich JN. PMID: 23006324; PMCID: PMC3461933.
      View in: PubMed   Mentions: 5     Fields:    
    184. TRP-ing up brain tumors. Nat Med. 2012 Aug; 18(8):1175-6. Schonberg DL, Bao S, Rich JN. PMID: 22869181.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    185. Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair. Trends Neurosci. 2012 Oct; 35(10):619-28. Li M, Hale JS, Rich JN, Ransohoff RM, Lathia JD. PMID: 22784557; PMCID: PMC3461091.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    186. The quest for self-identity: not all cancer stem cells are the same. Clin Cancer Res. 2012 Jul 01; 18(13):3495-8. Hjelmeland AB, Rich JN. PMID: 22711710; PMCID: PMC3389128.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    187. All-cause mortality and obstructive sleep apnea severity revisited. Otolaryngol Head Neck Surg. 2012 Sep; 147(3):583-7. Rich J, Raviv A, Raviv N, Brietzke SE. PMID: 22687326.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    188. Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity. Genes Dev. 2012 Jun 01; 26(11):1247-62. Kim Y, Kim E, Wu Q, Guryanova O, Hitomi M, Lathia JD, Serwanski D, Sloan AE, Weil RJ, Lee J, Nishiyama A, Bao S, Hjelmeland AB, Rich JN. PMID: 22661233; PMCID: PMC3371412.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    189. MET signaling regulates glioblastoma stem cells. Cancer Res. 2012 Aug 01; 72(15):3828-38. Joo KM, Jin J, Kim E, Ho Kim K, Kim Y, Gu Kang B, Kang YJ, Lathia JD, Cheong KH, Song PH, Kim H, Seol HJ, Kong DS, Lee JI, Rich JN, Lee J, Nam DH. PMID: 22617325.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    190. Holding on to stemness. Nat Cell Biol. 2012 May 02; 14(5):450-2. Lathia JD, Rich JN. PMID: 22552145.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    191. Phase 1 trial of dasatinib plus erlotinib in adults with recurrent malignant glioma. J Neurooncol. 2012 Jul; 108(3):499-506. Reardon DA, Vredenburgh JJ, Desjardins A, Peters KB, Sathornsumetee S, Threatt S, Sampson JH, Herndon JE, Coan A, McSherry F, Rich JN, McLendon RE, Zhang S, Friedman HS. PMID: 22407177; PMCID: PMC3690584.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    192. Endothelial expression of TNF receptor-1 generates a proapoptotic signal inhibited by integrin α6β1 in glioblastoma. Cancer Res. 2012 Mar 15; 72(6):1428-37. Huang P, Rani MR, Ahluwalia MS, Bae E, Prayson RA, Weil RJ, Nowacki AS, Hedayat H, Sloan AE, Lathia JD, Rich JN, Tipps R, Gladson CL. PMID: 22396498; PMCID: PMC3428239.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    193. Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth. J Exp Med. 2012 Mar 12; 209(3):507-20. Hamerlik P, Lathia JD, Rasmussen R, Wu Q, Bartkova J, Lee M, Moudry P, Bartek J, Fischer W, Lukas J, Rich JN, Bartek J. PMID: 22393126; PMCID: PMC3302235.
      View in: PubMed   Mentions: 221     Fields:    Translation:HumansCells
    194. Phase II study of Gleevec plus hydroxyurea in adults with progressive or recurrent low-grade glioma. Cancer. 2012 Oct 01; 118(19):4759-67. Reardon DA, Desjardins A, Vredenburgh JJ, Herndon JE, Coan A, Gururangan S, Peters KB, McLendon R, Sathornsumetee S, Rich JN, Lipp ES, Janney D, Friedman HS. PMID: 22371319; PMCID: PMC3748946.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    195. Molecularly targeted therapy in neuro-oncology. Handb Clin Neurol. 2012; 104:255-78. Sathornsumetee S, Rich JN. PMID: 22230448.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    196. Notch signaling in cancer stem cells. Adv Exp Med Biol. 2012; 727:174-85. Wang J, Sullenger BA, Rich JN. PMID: 22399347.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    197. Synthesis and preliminary evaluation of n.c.a. iodoquine: a novel radiotracer with high uptake in cells with high ALDH1 expression. Curr Radiopharm. 2012 Jan; 5(1):47-58. Chin BB, Hjelemand A, Rich J, Song H, Lascola C, Storms R, McLendon R, Reiman R, Greer KL, Metzler SD, McDougald D, Dai D, Vaidyanathan G. PMID: 21864242.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    198. Twisted tango: brain tumor neurovascular interactions. Nat Neurosci. 2011 Oct 26; 14(11):1375-81. Hjelmeland AB, Lathia JD, Sathornsumetee S, Rich JN. PMID: 22030548; PMCID: PMC3615423.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    199. Outcome after bevacizumab clinical trial therapy among recurrent grade III malignant glioma patients. J Neurooncol. 2012 Mar; 107(1):213-21. Reardon DA, Herndon JE, Peters K, Desjardins A, Coan A, Lou E, Sumrall A, Turner S, Sathornsumetee S, Rich JN, Boulton S, Lipp ES, Friedman HS, Vredenburgh JJ. PMID: 21997879; PMCID: PMC3403724.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    200. Pharmacokinetic drug interaction between AEE788 and RAD001 causing thrombocytopenia in patients with glioblastoma. Cancer Chemother Pharmacol. 2012 Jan; 69(1):281-7. Reardon DA, Cloughesy T, Rich J, Alfred Yung WK, Yung L, DiLea C, Huang J, Dugan M, Mietlowski W, Maes A, Conrad C. PMID: 21984222.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    201. Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells. PLoS One. 2011; 6(9):e24807. Lathia JD, Gallagher J, Myers JT, Li M, Vasanji A, McLendon RE, Hjelmeland AB, Huang AY, Rich JN. PMID: 21961046; PMCID: PMC3178553.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    202. Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions. Cell Death Dis. 2011 Sep 01; 2:e200. Lathia JD, Hitomi M, Gallagher J, Gadani SP, Adkins J, Vasanji A, Liu L, Eyler CE, Heddleston JM, Wu Q, Minhas S, Soeda A, Hoeppner DJ, Ravin R, McKay RD, McLendon RE, Corbeil D, Chenn A, Hjelmeland AB, Park DM, Rich JN. PMID: 21881602; PMCID: PMC3186899.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansCells
    203. Reduced neutrophil apoptosis in diabetic mice during staphylococcal infection leads to prolonged Tnfα production and reduced neutrophil clearance. PLoS One. 2011; 6(8):e23633. Hanses F, Park S, Rich J, Lee JC. PMID: 21912601; PMCID: PMC3166063.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    204. Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential. Cell Death Differ. 2012 Mar; 19(3):428-39. Heddleston JM, Wu Q, Rivera M, Minhas S, Lathia JD, Sloan AE, Iliopoulos O, Hjelmeland AB, Rich JN. PMID: 21836617; PMCID: PMC3229666.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    205. An epidemiologic study of snoring and all-cause mortality. Otolaryngol Head Neck Surg. 2011 Aug; 145(2):341-6. Rich J, Raviv A, Raviv N, Brietzke SE. PMID: 21493281.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    206. Glioma development: where did it all go wrong? Cell. 2011 Jul 22; 146(2):187-8. Sukhdeo K, Hambardzumyan D, Rich JN. PMID: 21784240.
      View in: PubMed   Mentions: 13     Fields:    
    207. Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival. Endocr Relat Cancer. 2011 Aug; 18(4):491-503. Zheng Q, Dunlap SM, Zhu J, Downs-Kelly E, Rich J, Hursting SD, Berger NA, Reizes O. PMID: 21636700; PMCID: PMC3197719.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    208. Phase I study of sunitinib and irinotecan for patients with recurrent malignant glioma. J Neurooncol. 2011 Dec; 105(3):621-7. Reardon DA, Vredenburgh JJ, Coan A, Desjardins A, Peters KB, Gururangan S, Sathornsumetee S, Rich JN, Herndon JE, Friedman HS. PMID: 21744079; PMCID: PMC3748953.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCTClinical Trials
    209. Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell. 2011 Jul 08; 146(1):53-66. Eyler CE, Wu Q, Yan K, MacSwords JM, Chandler-Militello D, Misuraca KL, Lathia JD, Forrester MT, Lee J, Stamler JS, Goldman SA, Bredel M, McLendon RE, Sloan AE, Hjelmeland AB, Rich JN. PMID: 21729780; PMCID: PMC3144745.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansAnimalsCells
    210. HIF induces human embryonic stem cell markers in cancer cells. Cancer Res. 2011 Jul 01; 71(13):4640-52. Mathieu J, Zhang Z, Zhou W, Wang AJ, Heddleston JM, Pinna CM, Hubaud A, Stadler B, Choi M, Bar M, Tewari M, Liu A, Vessella R, Rostomily R, Born D, Horwitz M, Ware C, Blau CA, Cleary MA, Rich JN, Ruohola-Baker H. PMID: 21712410; PMCID: PMC3129496.
      View in: PubMed   Mentions: 256     Fields:    Translation:HumansCells
    211. Seeing is believing: are cancer stem cells the Loch Ness monster of tumor biology? Stem Cell Rev Rep. 2011 Jun; 7(2):227-37. Lathia JD, Venere M, Rao MS, Rich JN. PMID: 20957452; PMCID: PMC3093710.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    212. Deadly teamwork: neural cancer stem cells and the tumor microenvironment. Cell Stem Cell. 2011 May 06; 8(5):482-5. Lathia JD, Heddleston JM, Venere M, Rich JN. PMID: 21549324; PMCID: PMC3494093.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimalsCells
    213. Cancer stem cells in gliomas: identifying and understanding the apex cell in cancer's hierarchy. Glia. 2011 Aug; 59(8):1148-54. Venere M, Fine HA, Dirks PB, Rich JN. PMID: 21547954; PMCID: PMC3107874.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    214. Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3. Cancer Cell. 2011 Apr 12; 19(4):498-511. Guryanova OA, Wu Q, Cheng L, Lathia JD, Huang Z, Yang J, MacSwords J, Eyler CE, McLendon RE, Heddleston JM, Shou W, Hambardzumyan D, Lee J, Hjelmeland AB, Sloan AE, Bredel M, Stark GR, Rich JN, Bao S. PMID: 21481791; PMCID: PMC3076106.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansAnimalsCells
    215. Elevated invasive potential of glioblastoma stem cells. Biochem Biophys Res Commun. 2011 Mar 25; 406(4):643-8. Cheng L, Wu Q, Guryanova OA, Huang Z, Huang Q, Rich JN, Bao S. PMID: 21371437; PMCID: PMC3065536.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    216. L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1. EMBO J. 2011 Mar 02; 30(5):800-13. Cheng L, Wu Q, Huang Z, Guryanova OA, Huang Q, Shou W, Rich JN, Bao S. PMID: 21297581; PMCID: PMC3049209.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    217. Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells. Nat Cell Biol. 2011 Feb; 13(2):142-52. Huang Z, Wu Q, Guryanova OA, Cheng L, Shou W, Rich JN, Bao S. PMID: 21258371; PMCID: PMC3076066.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    218. Bacterial flavohemoglobin: a molecular tool to probe mammalian nitric oxide biology. Biotechniques. 2011 Jan; 50(1):41-5. Forrester MT, Eyler CE, Rich JN. PMID: 21231921; PMCID: PMC3096140.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    219. Molecular targeting of neural cancer stem cells: TTAGGG, you're it! Clin Cancer Res. 2011 Jan 01; 17(1):3-5. Hjelmeland AB, Rich JN. PMID: 21208901; PMCID: PMC3099413.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    220. Glioma stem cell maintenance: the role of the microenvironment. Curr Pharm Des. 2011; 17(23):2386-401. Heddleston JM, Hitomi M, Venere M, Flavahan WA, Yang K, Kim Y, Minhas S, Rich JN, Hjelmeland AB. PMID: 21827414; PMCID: PMC3615428.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    221. Using a stem cell-based signature to guide therapeutic selection in cancer. Cancer Res. 2011 Mar 01; 71(5):1772-80. Shats I, Gatza ML, Chang JT, Mori S, Wang J, Rich J, Nevins JR. PMID: 21169407; PMCID: PMC3049992.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    222. Acidic stress promotes a glioma stem cell phenotype. Cell Death Differ. 2011 May; 18(5):829-40. Hjelmeland AB, Wu Q, Heddleston JM, Choudhary GS, MacSwords J, Lathia JD, McLendon R, Lindner D, Sloan A, Rich JN. PMID: 21127501; PMCID: PMC3095828.
      View in: PubMed   Mentions: 177     Fields:    Translation:HumansCells
    223. Glioblastoma Stem Cells: A Neuropathologist's View. J Oncol. 2011; 2011:397195. McLendon RE, Rich JN. PMID: 21052560; PMCID: PMC2971570.
      View in: PubMed   Mentions: 12  
    224. Improving the radiosensitivity of radioresistant and hypoxic glioblastoma. Future Oncol. 2010 Oct; 6(10):1591-601. Sheehan JP, Shaffrey ME, Gupta B, Larner J, Rich JN, Park DM. PMID: 21062158.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    225. Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy. J Neurooncol. 2011 Jun; 103(2):371-9. Reardon DA, Desjardins A, Peters K, Gururangan S, Sampson J, Rich JN, McLendon R, Herndon JE, Marcello J, Threatt S, Friedman AH, Vredenburgh JJ, Friedman HS. PMID: 20853132; PMCID: PMC3102515.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCTClinical Trials
    226. Phase II trial of bevacizumab and erlotinib in patients with recurrent malignant glioma. Neuro Oncol. 2010 Dec; 12(12):1300-10. Sathornsumetee S, Desjardins A, Vredenburgh JJ, McLendon RE, Marcello J, Herndon JE, Mathe A, Hamilton M, Rich JN, Norfleet JA, Gururangan S, Friedman HS, Reardon DA. PMID: 20716591; PMCID: PMC3018944.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCTClinical Trials
    227. Dynamic and transient cancer stem cells nurture melanoma. Nat Med. 2010 Jul; 16(7):758. Weinberg R, Fisher DE, Rich J. PMID: 20613753; PMCID: PMC6063736.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    228. Potential therapeutic implications of cancer stem cells in glioblastoma. Biochem Pharmacol. 2010 Sep 01; 80(5):654-65. Cheng L, Bao S, Rich JN. PMID: 20457135; PMCID: PMC2897968.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    229. Integrin alpha 6 regulates glioblastoma stem cells. Cell Stem Cell. 2010 May 07; 6(5):421-32. Lathia JD, Gallagher J, Heddleston JM, Wang J, Eyler CE, Macswords J, Wu Q, Vasanji A, McLendon RE, Hjelmeland AB, Rich JN. PMID: 20452317; PMCID: PMC2884275.
      View in: PubMed   Mentions: 327     Fields:    Translation:HumansAnimalsCells
    230. Informed consent in pediatric surgery: Do parents understand the risks? Arch Otolaryngol Head Neck Surg. 2010 Mar; 136(3):265-9. Nadeau DP, Rich JN, Brietzke SE. PMID: 20231645.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    231. Targeting A20 decreases glioma stem cell survival and tumor growth. PLoS Biol. 2010 Feb 23; 8(2):e1000319. Hjelmeland AB, Wu Q, Wickman S, Eyler C, Heddleston J, Shi Q, Lathia JD, Macswords J, Lee J, McLendon RE, Rich JN. PMID: 20186265; PMCID: PMC2826371.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    232. Medical oncology: treatment and management of malignant gliomas. Nat Rev Clin Oncol. 2010 Feb; 7(2):75-7. Park DM, Sathornsumetee S, Rich JN. PMID: 20118976.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    233. Hypoxia inducible factors in cancer stem cells. Br J Cancer. 2010 Mar 02; 102(5):789-95. Heddleston JM, Li Z, Lathia JD, Bao S, Hjelmeland AB, Rich JN. PMID: 20104230; PMCID: PMC2833246.
      View in: PubMed   Mentions: 187     Fields:    Translation:HumansAnimalsCells
    234. Notch promotes radioresistance of glioma stem cells. Stem Cells. 2010 Jan; 28(1):17-28. Wang J, Wakeman TP, Lathia JD, Hjelmeland AB, Wang XF, White RR, Rich JN, Sullenger BA. PMID: 19921751; PMCID: PMC2825687.
      View in: PubMed   Mentions: 298     Fields:    Translation:HumansAnimalsCells
    235. Hypoxia and hypoxia inducible factors in cancer stem cell maintenance. Curr Top Microbiol Immunol. 2010; 345:21-30. Li Z, Rich JN. PMID: 20582533.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    236. Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance. Genes Cancer. 2010 Jan 01; 1(1):50-61. Cao Y, Lathia JD, Eyler CE, Wu Q, Li Z, Wang H, McLendon RE, Hjelmeland AB, Rich JN. PMID: 20657792; PMCID: PMC2906804.
      View in: PubMed   Mentions: 35  
    237. Receptor channel TRPC6 is a key mediator of Notch-driven glioblastoma growth and invasiveness. Cancer Res. 2010 Jan 01; 70(1):418-27. Chigurupati S, Venkataraman R, Barrera D, Naganathan A, Madan M, Paul L, Pattisapu JV, Kyriazis GA, Sugaya K, Bushnev S, Lathia JD, Rich JN, Chan SL. PMID: 20028870.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCells
    238. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle. 2009 Oct 15; 8(20):3274-84. Heddleston JM, Li Z, McLendon RE, Hjelmeland AB, Rich JN. PMID: 19770585; PMCID: PMC2825672.
      View in: PubMed   Mentions: 386     Fields:    Translation:HumansAnimalsCells
    239. Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth. Stem Cells. 2009 Oct; 27(10):2393-404. Wang H, Lathia JD, Wu Q, Wang J, Li Z, Heddleston JM, Eyler CE, Elderbroom J, Gallagher J, Schuschu J, MacSwords J, Cao Y, McLendon RE, Wang XF, Hjelmeland AB, Rich JN. PMID: 19658188; PMCID: PMC2825688.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansAnimalsCells
    240. Squelching glioblastoma stem cells by targeting REST for proteasomal degradation. Trends Neurosci. 2009 Nov; 32(11):559-65. Zhang P, Lathia JD, Flavahan WA, Rich JN, Mattson MP. PMID: 19748686; PMCID: PMC2767465.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    241. Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy. Cancer. 2009 Aug 01; 115(15):3501-11. Affronti ML, Heery CR, Herndon JE, Rich JN, Reardon DA, Desjardins A, Vredenburgh JJ, Friedman AH, Bigner DD, Friedman HS. PMID: 19514083.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    242. Biology of glioma cancer stem cells. Mol Cells. 2009 Jul 31; 28(1):7-12. Park DM, Rich JN. PMID: 19655094.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    243. NDRG4 is required for cell cycle progression and survival in glioblastoma cells. J Biol Chem. 2009 Sep 11; 284(37):25160-9. Schilling SH, Hjelmeland AB, Radiloff DR, Liu IM, Wakeman TP, Fielhauer JR, Foster EH, Lathia JD, Rich JN, Wang XF, Datto MB. PMID: 19592488; PMCID: PMC2757219.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    244. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell. 2009 Jun 02; 15(6):501-13. Li Z, Bao S, Wu Q, Wang H, Eyler C, Sathornsumetee S, Shi Q, Cao Y, Lathia J, McLendon RE, Hjelmeland AB, Rich JN. PMID: 19477429; PMCID: PMC2693960.
      View in: PubMed   Mentions: 659     Fields:    Translation:HumansAnimalsCells
    245. Cancer stem cells in brain tumor biology. Cold Spring Harb Symp Quant Biol. 2008; 73:411-20. Rich JN, Eyler CE. PMID: 19329578; PMCID: PMC2822444.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    246. Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma. Neuro Oncol. 2009 Oct; 11(5):556-61. Quinn JA, Jiang SX, Reardon DA, Desjardins A, Vredenburgh JJ, Rich JN, Gururangan S, Friedman AH, Bigner DD, Sampson JH, McLendon RE, Herndon JE, Walker A, Friedman HS. PMID: 19289491; PMCID: PMC2765345.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    247. Turning cancer stem cells inside out: an exploration of glioma stem cell signaling pathways. J Biol Chem. 2009 Jun 19; 284(25):16705-16709. Li Z, Wang H, Eyler CE, Hjelmeland AB, Rich JN. PMID: 19286664; PMCID: PMC2719304.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    248. Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma. J Clin Oncol. 2009 Mar 10; 27(8):1262-7. Quinn JA, Jiang SX, Reardon DA, Desjardins A, Vredenburgh JJ, Rich JN, Gururangan S, Friedman AH, Bigner DD, Sampson JH, McLendon RE, Herndon JE, Walker A, Friedman HS. PMID: 19204199; PMCID: PMC2667825.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansCTClinical Trials
    249. Phase II trial of Gliadel plus O6-benzylguanine in adults with recurrent glioblastoma multiforme. Clin Cancer Res. 2009 Feb 01; 15(3):1064-8. Quinn JA, Jiang SX, Carter J, Reardon DA, Desjardins A, Vredenburgh JJ, Rich JN, Gururangan S, Friedman AH, Bigner DD, Sampson JH, McLendon RE, Herndon JE, Threatt S, Friedman HS. PMID: 19188181; PMCID: PMC2710963.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    250. Defects in innate immunity predispose C57BL/6J-Leprdb/Leprdb mice to infection by Staphylococcus aureus. Infect Immun. 2009 Mar; 77(3):1008-14. Park S, Rich J, Hanses F, Lee JC. PMID: 19103772; PMCID: PMC2643648.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    251. c-Myc is required for maintenance of glioma cancer stem cells. PLoS One. 2008; 3(11):e3769. Wang J, Wang H, Li Z, Wu Q, Lathia JD, McLendon RE, Hjelmeland AB, Rich JN. PMID: 19020659; PMCID: PMC2582454.
      View in: PubMed   Mentions: 212     Fields:    Translation:AnimalsCells
    252. Bevacizumab plus irinotecan in recurrent WHO grade 3 malignant gliomas. Clin Cancer Res. 2008 Nov 01; 14(21):7068-73. Desjardins A, Reardon DA, Herndon JE, Marcello J, Quinn JA, Rich JN, Sathornsumetee S, Gururangan S, Sampson J, Bailey L, Bigner DD, Friedman AH, Friedman HS, Vredenburgh JJ. PMID: 18981004; PMCID: PMC3671765.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCTClinical Trials
    253. Designer therapies for glioblastoma multiforme. Ann N Y Acad Sci. 2008 Oct; 1142:108-32. Sathornsumetee S, Rich JN. PMID: 18990124.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    254. Brain cancer stem cells display preferential sensitivity to Akt inhibition. Stem Cells. 2008 Dec; 26(12):3027-36. Eyler CE, Foo WC, LaFiura KM, McLendon RE, Hjelmeland AB, Rich JN. PMID: 18802038; PMCID: PMC2739007.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    255. Efficacy of high-dose chemotherapy or standard salvage therapy in patients with recurrent medulloblastoma. Neuro Oncol. 2008 Oct; 10(5):745-51. Gururangan S, Krauser J, Watral MA, Driscoll T, Larrier N, Reardon DA, Rich JN, Quinn JA, Vredenburgh JJ, Desjardins A, McLendon RE, Fuchs H, Kurtzberg J, Friedman HS. PMID: 18755919; PMCID: PMC2666251.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    256. Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer Res. 2008 Aug 01; 68(15):6043-8. Bao S, Wu Q, Li Z, Sathornsumetee S, Wang H, McLendon RE, Hjelmeland AB, Rich JN. PMID: 18676824; PMCID: PMC2739001.
      View in: PubMed   Mentions: 195     Fields:    Translation:HumansAnimalsCells
    257. Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis. J Clin Oncol. 2008 Jun 10; 26(17):2839-45. Eyler CE, Rich JN. PMID: 18539962; PMCID: PMC2739000.
      View in: PubMed   Mentions: 302     Fields:    Translation:HumansAnimalsCells
    258. The Implications of the Cancer Stem Cell Hypothesis for Neuro-Oncology and Neurology. Future Neurol. 2008 May 01; 3(3):265-273. Rich JN. PMID: 19763280; PMCID: PMC2744958.
      View in: PubMed   Mentions: 2  
    259. Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma. Neuro Oncol. 2008 Jun; 10(3):330-40. Reardon DA, Desjardins A, Vredenburgh JJ, Sathornsumetee S, Rich JN, Quinn JA, Lagattuta TF, Egorin MJ, Gururangan S, McLendon R, Herndon JE, Friedman AH, Salvado AJ, Friedman HS. PMID: 18359865; PMCID: PMC2563055.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    260. A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost. Neuro Oncol. 2008 Apr; 10(2):182-9. Reardon DA, Zalutsky MR, Akabani G, Coleman RE, Friedman AH, Herndon JE, McLendon RE, Pegram CN, Quinn JA, Rich JN, Vredenburgh JJ, Desjardins A, Guruangan S, Boulton S, Raynor RH, Dowell JM, Wong TZ, Zhao XG, Friedman HS, Bigner DD. PMID: 18287339; PMCID: PMC2613820.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    261. The emerging role of anti-angiogenic therapy for malignant glioma. Curr Treat Options Oncol. 2008 Feb; 9(1):1-22. Reardon DA, Desjardins A, Rich JN, Vredenburgh JJ. PMID: 18256938.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    262. Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan. J Clin Oncol. 2008 Jan 10; 26(2):271-8. Sathornsumetee S, Cao Y, Marcello JE, Herndon JE, McLendon RE, Desjardins A, Friedman HS, Dewhirst MW, Vredenburgh JJ, Rich JN. PMID: 18182667; PMCID: PMC3930173.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansCTClinical Trials
    263. Diagnosis and treatment of high-grade astrocytoma. Neurol Clin. 2007 Nov; 25(4):1111-39, x. Sathornsumetee S, Rich JN, Reardon DA. PMID: 17964028.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    264. Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. J Clin Oncol. 2007 Oct 20; 25(30):4722-9. Vredenburgh JJ, Desjardins A, Herndon JE, Marcello J, Reardon DA, Quinn JA, Rich JN, Sathornsumetee S, Gururangan S, Sampson J, Wagner M, Bailey L, Bigner DD, Friedman AH, Friedman HS. PMID: 17947719.
      View in: PubMed   Mentions: 579     Fields:    Translation:HumansCTClinical Trials
    265. Chemotherapy and cancer stem cells. Cell Stem Cell. 2007 Oct 11; 1(4):353-5. Rich JN, Bao S. PMID: 18371369.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    266. Making a tumour's bed: glioblastoma stem cells and the vascular niche. Nat Rev Cancer. 2007 10; 7(10):733-6. Gilbertson RJ, Rich JN. PMID: 17882276.
      View in: PubMed   Mentions: 338     Fields:    Translation:HumansCells
    267. Cancer stem cells in radiation resistance. Cancer Res. 2007 Oct 01; 67(19):8980-4. Rich JN. PMID: 17908997.
      View in: PubMed   Mentions: 200     Fields:    Translation:HumansAnimalsCells
    268. Second messenger systems in human gliomas. Arch Pathol Lab Med. 2007 Oct; 131(10):1585-90. McLendon RE, Turner K, Perkinson K, Rich J. PMID: 17922598.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    269. The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion. Mol Cancer Ther. 2007 Sep; 6(9):2449-57. Hjelmeland AB, Lattimore KP, Fee BE, Shi Q, Wickman S, Keir ST, Hjelmeland MD, Batt D, Bigner DD, Friedman HS, Rich JN. PMID: 17766837.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    270. Molecularly targeted therapy for malignant glioma. Cancer. 2007 Jul 01; 110(1):13-24. Sathornsumetee S, Reardon DA, Desjardins A, Quinn JA, Vredenburgh JJ, Rich JN. PMID: 17520692.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansCells
    271. A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth. Mol Carcinog. 2007 Jun; 46(6):488-96. Shi Q, Hjelmeland AB, Keir ST, Song L, Wickman S, Jackson D, Ohmori O, Bigner DD, Friedman HS, Rich JN. PMID: 17219439.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCells
    272. Neurofibromatosis type 2. Neurology. 2007 Mar 27; 68(13):E14. Sathornsumetee S, DesJardins A, Reardon DA, Rich JN, Vredenburgh JJ. PMID: 17389295.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    273. Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin Cancer Res. 2007 Feb 15; 13(4):1253-9. Vredenburgh JJ, Desjardins A, Herndon JE, Dowell JM, Reardon DA, Quinn JA, Rich JN, Sathornsumetee S, Gururangan S, Wagner M, Bigner DD, Friedman AH, Friedman HS. PMID: 17317837.
      View in: PubMed   Mentions: 447     Fields:    Translation:HumansCTClinical Trials
    274. Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas. J Neurooncol. 2007 May; 83(1):53-60. Desjardins A, Quinn JA, Vredenburgh JJ, Sathornsumetee S, Friedman AH, Herndon JE, McLendon RE, Provenzale JM, Rich JN, Sampson JH, Gururangan S, Dowell JM, Salvado A, Friedman HS, Reardon DA. PMID: 17245623.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCTClinical Trials
    275. Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases. Oncogene. 2007 Jun 14; 26(28):4084-94. Shi Q, Bao S, Song L, Wu Q, Bigner DD, Hjelmeland AB, Rich JN. PMID: 17213807.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    276. Antiangiogenic therapy in malignant glioma: promise and challenge. Curr Pharm Des. 2007; 13(35):3545-58. Sathornsumetee S, Rich JN. PMID: 18220791.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    277. Malignant glioma drug discovery - targeting protein kinases. Expert Opin Drug Discov. 2007 Jan; 2(1):1-17. Sathornsumetee S, Vredenburgh KA, Lattimore KP, Rich JN. PMID: 23496034.
      View in: PubMed   Mentions: 2     Fields:    
    278. Phase II study of Cloretazine for the treatment of adults with recurrent glioblastoma multiforme. Neuro Oncol. 2007 Jan; 9(1):70-4. Badruddoja MA, Penne K, Desjardins A, Reardon DA, Rich JN, Quinn JA, Sathornsumetee S, Friedman AH, Bigner DD, Herndon JE, Cahill A, Friedman HS, Vredenburgh JJ. PMID: 17108065; PMCID: PMC1828104.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    279. The cancer stem cell: a new therapeutic paradigm? Expert Rev Anticancer Ther. 2006 Nov; 6(11):1531-3. Rich JN. PMID: 17134357.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    280. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006 Dec 07; 444(7120):756-60. Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN. PMID: 17051156.
      View in: PubMed   Mentions: 2835     Fields:    Translation:HumansAnimalsCells
    281. New approaches to primary brain tumor treatment. Anticancer Drugs. 2006 Oct; 17(9):1003-16. Sathornsumetee S, Rich JN. PMID: 17001172.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    282. Vandetanib, a novel multitargeted kinase inhibitor, in cancer therapy. Drugs Today (Barc). 2006 Oct; 42(10):657-70. Sathornsumetee S, Rich JN. PMID: 17136225.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    283. APOE4-VLDL inhibits the HDL-activated phosphatidylinositol 3-kinase/Akt Pathway via the phosphoinositol phosphatase SHIP2. Circ Res. 2006 Oct 13; 99(8):829-36. DeKroon R, Robinette JB, Hjelmeland AB, Wiggins E, Blackwell M, Mihovilovic M, Fujii M, York J, Hart J, Kontos C, Rich J, Strittmatter WJ. PMID: 16973905.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    284. AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma. Cancer Res. 2006 Sep 01; 66(17):8722-30. Sathornsumetee S, Hjelmeland AB, Keir ST, McLendon RE, Batt D, Ramsey T, Yusuff N, Rasheed BK, Kieran MW, Laforme A, Bigner DD, Friedman HS, Rich JN. PMID: 16951188.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    285. Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res. 2006 Aug 15; 66(16):7843-8. Bao S, Wu Q, Sathornsumetee S, Hao Y, Li Z, Hjelmeland AB, Shi Q, McLendon RE, Bigner DD, Rich JN. PMID: 16912155.
      View in: PubMed   Mentions: 588     Fields:    Translation:HumansAnimalsCells
    286. New treatment strategies for malignant gliomas. Expert Rev Anticancer Ther. 2006 Jul; 6(7):1087-104. Sathornsumetee S, Rich JN. PMID: 16831080.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    287. CD4+ T cells and CXC chemokines modulate the pathogenesis of Staphylococcus aureus wound infections. Proc Natl Acad Sci U S A. 2006 Jul 05; 103(27):10408-10413. McLoughlin RM, Solinga RM, Rich J, Zaleski KJ, Cocchiaro JL, Risley A, Tzianabos AO, Lee JC. PMID: 16801559; PMCID: PMC1502471.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    288. Novel human IgG2b/murine chimeric antitenascin monoclonal antibody construct radiolabeled with 131I and administered into the surgically created resection cavity of patients with malignant glioma: phase I trial results. J Nucl Med. 2006 Jun; 47(6):912-8. Reardon DA, Quinn JA, Akabani G, Coleman RE, Friedman AH, Friedman HS, Herndon JE, McLendon RE, Pegram CN, Provenzale JM, Dowell JM, Rich JN, Vredenburgh JJ, Desjardins A, Sampson JH, Gururangan S, Wong TZ, Badruddoja MA, Zhao XG, Bigner DD, Zalutsky MR. PMID: 16741299.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsPHPublic HealthCTClinical Trials
    289. Recent advances in the treatment of malignant astrocytoma. J Clin Oncol. 2006 Mar 10; 24(8):1253-65. Reardon DA, Rich JN, Friedman HS, Bigner DD. PMID: 16525180.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansCells
    290. Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma. Clin Cancer Res. 2006 Feb 01; 12(3 Pt 1):860-8. Reardon DA, Quinn JA, Vredenburgh JJ, Gururangan S, Friedman AH, Desjardins A, Sathornsumetee S, Herndon JE, Dowell JM, McLendon RE, Provenzale JM, Sampson JH, Smith RP, Swaisland AJ, Ochs JS, Lyons P, Tourt-Uhlig S, Bigner DD, Friedman HS, Rich JN. PMID: 16467100.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCTClinical Trials
    291. Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: phase II study results. J Clin Oncol. 2006 Jan 01; 24(1):115-22. Reardon DA, Akabani G, Coleman RE, Friedman AH, Friedman HS, Herndon JE, McLendon RE, Pegram CN, Provenzale JM, Quinn JA, Rich JN, Vredenburgh JJ, Desjardins A, Gururangan S, Guruangan S, Badruddoja M, Dowell JM, Wong TZ, Zhao XG, Zalutsky MR, Bigner DD. PMID: 16382120.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCTClinical Trials
    292. Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme. J Clin Oncol. 2005 Dec 20; 23(36):9359-68. Reardon DA, Egorin MJ, Quinn JA, Rich JN, Rich JN, Gururangan S, Gururangan I, Vredenburgh JJ, Desjardins A, Sathornsumetee S, Provenzale JM, Herndon JE, Dowell JM, Badruddoja MA, McLendon RE, Lagattuta TF, Kicielinski KP, Dresemann G, Sampson JH, Friedman AH, Salvado AJ, Friedman HS. PMID: 16361636.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCTClinical Trials
    293. Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity. Cancer Res. 2005 Dec 15; 65(24):11276-81. Hjelmeland AB, Hjelmeland MD, Shi Q, Hart JL, Bigner DD, Wang XF, Kontos CD, Rich JN. PMID: 16357132.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    294. ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors. Clin Cancer Res. 2005 Nov 15; 11(22):8145-57. Rich JN, Sathornsumetee S, Keir ST, Kieran MW, Laforme A, Kaipainen A, McLendon RE, Graner MW, Rasheed BK, Wang L, Reardon DA, Ryan AJ, Wheeler C, Dimery I, Bigner DD, Friedman HS. PMID: 16299247.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    295. Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. J Clin Oncol. 2005 Oct 01; 23(28):7178-87. Quinn JA, Desjardins A, Weingart J, Brem H, Dolan ME, Delaney SM, Vredenburgh J, Rich J, Friedman AH, Reardon DA, Sampson JH, Pegg AE, Moschel RC, Birch R, McLendon RE, Provenzale JM, Gururangan S, Dancey JE, Maxwell J, Tourt-Uhlig S, Herndon JE, Bigner DD, Friedman HS. PMID: 16192602.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCTClinical Trials
    296. The pathogenesis of Staphylococcus aureus infection in the diabetic NOD mouse. Diabetes. 2005 Oct; 54(10):2904-10. Rich J, Lee JC. PMID: 16186391.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    297. Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma. Cancer. 2005 Oct 01; 104(7):1478-86. Reardon DA, Quinn JA, Rich JN, Desjardins A, Vredenburgh J, Gururangan S, Sathornsumetee S, Badruddoja M, McLendon R, Provenzale J, Herndon JE, Dowell JM, Burkart JL, Newton HB, Friedman AH, Friedman HS. PMID: 16088964.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCTClinical Trials
    298. Chemotherapy and novel therapeutic approaches in malignant glioma. Front Biosci. 2005 Sep 01; 10:2645-68. Desjardins A, Rich JN, Quinn JA, Vredenburgh J, Gururangan S, Sathornsumetee S, Reardon DA, Friedman AH, Bigner DD, Friedman HS. PMID: 15970525.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    299. Gene expression profiling and genetic markers in glioblastoma survival. Cancer Res. 2005 May 15; 65(10):4051-8. Rich JN, Hans C, Jones B, Iversen ES, McLendon RE, Rasheed BK, Dobra A, Dressman HK, Bigner DD, Nevins JR, West M. PMID: 15899794.
      View in: PubMed   Mentions: 127     Fields:    Translation:Humans
    300. Human identification from the ankle with pre- and postsurgical radiographs. J Clin Forensic Med. 2005 Feb; 12(1):5-9. Dean DE, Tatarek NE, Rich J, Brogdon BG, Powers RH. PMID: 15763682.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    301. Phase II trial of irinotecan plus celecoxib in adults with recurrent malignant glioma. Cancer. 2005 Jan 15; 103(2):329-38. Reardon DA, Quinn JA, Vredenburgh J, Rich JN, Gururangan S, Badruddoja M, Herndon JE, Dowell JM, Friedman AH, Friedman HS. PMID: 15558802.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCTClinical Trials
    302. Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition. Mol Cancer Ther. 2005 Jan; 4(1):101-12. Goudar RK, Shi Q, Hjelmeland MD, Keir ST, McLendon RE, Wikstrand CJ, Reese ED, Conrad CA, Traxler P, Lane HA, Reardon DA, Cavenee WK, Wang XF, Bigner DD, Friedman HS, Rich JN. PMID: 15657358.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    303. Secreted protein acidic, rich in cysteine (SPARC), mediates cellular survival of gliomas through AKT activation. J Biol Chem. 2004 Dec 10; 279(50):52200-9. Shi Q, Bao S, Maxwell JA, Reese ED, Friedman HS, Bigner DD, Wang XF, Rich JN. PMID: 15469933.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    304. EGFR mutations and sensitivity to gefitinib. N Engl J Med. 2004 Sep 16; 351(12):1260-1; author reply 1260-1. Rich JN, Rasheed BK, Yan H. PMID: 15376352.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    305. SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility. Mol Cancer Ther. 2004 Jun; 3(6):737-45. Hjelmeland MD, Hjelmeland AB, Sathornsumetee S, Reese ED, Herbstreith MH, Laping NJ, Friedman HS, Bigner DD, Wang XF, Rich JN. PMID: 15210860.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    306. Resistance to tyrosine kinase inhibition by mutant epidermal growth factor receptor variant III contributes to the neoplastic phenotype of glioblastoma multiforme. Clin Cancer Res. 2004 May 01; 10(9):3216-24. Learn CA, Hartzell TL, Wikstrand CJ, Archer GE, Rich JN, Friedman AH, Friedman HS, Bigner DD, Sampson JH. PMID: 15131063.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    307. Development of novel targeted therapies in the treatment of malignant glioma. Nat Rev Drug Discov. 2004 May; 3(5):430-46. Rich JN, Bigner DD. PMID: 15136790.
      View in: PubMed   Mentions: 89     Fields:    Translation:Humans
    308. International Hermelin brain tumor symposium on matricellular proteins in normal and cancer cell-matrix interactions. Matrix Biol. 2004 Apr; 23(1):63-9. Bos TJ, Cohn SL, Kleinman HK, Murphy-Ulrich JE, Podhajcer OL, Rempel SA, Rich JN, Rutka JT, Sage EH, Thompson EW. PMID: 15230275.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    309. Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma. Neuro Oncol. 2004 Apr; 6(2):145-53. Quinn JA, Reardon DA, Friedman AH, Rich JN, Sampson JH, Vredenburgh J, Gururangan S, Provenzale JM, Walker A, Schweitzer H, Bigner DD, Tourt-Uhlig S, Herndon JE, Affronti ML, Jackson S, Allen D, Ziegler K, Bohlin C, Lentz C, Friedman HS. PMID: 15134629; PMCID: PMC1871988.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    310. Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway. Cancer Cell. 2004 Apr; 5(4):329-39. Bao S, Ouyang G, Bai X, Huang Z, Ma C, Liu M, Shao R, Anderson RM, Rich JN, Wang XF. PMID: 15093540.
      View in: PubMed   Mentions: 257     Fields:    Translation:HumansAnimalsCells
    311. Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma. Neuro Oncol. 2004 Apr; 6(2):134-44. Reardon DA, Quinn JA, Rich JN, Gururangan S, Vredenburgh J, Sampson JH, Provenzale JM, Walker A, Badruddoja M, Tourt-Uhlig S, Herndon JE, Dowell JM, Affronti ML, Jackson S, Allen D, Ziegler K, Silverman S, Bohlin C, Friedman AH, Bigner DD, Friedman HS. PMID: 15134628; PMCID: PMC1871982.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    312. Phase II trial of gefitinib in recurrent glioblastoma. J Clin Oncol. 2004 Jan 01; 22(1):133-42. Rich JN, Reardon DA, Peery T, Dowell JM, Quinn JA, Penne KL, Wikstrand CJ, Van Duyn LB, Dancey JE, McLendon RE, Kao JC, Stenzel TT, Ahmed Rasheed BK, Tourt-Uhlig SE, Herndon JE, Vredenburgh JJ, Sampson JH, Friedman AH, Bigner DD, Friedman HS. PMID: 14638850.
      View in: PubMed   Mentions: 239     Fields:    Translation:HumansCTClinical Trials
    313. Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors. J Neurooncol. 2003 Oct; 65(1):27-35. Sampson JH, Akabani G, Archer GE, Bigner DD, Berger MS, Friedman AH, Friedman HS, Herndon JE, Kunwar S, Marcus S, McLendon RE, Paolino A, Penne K, Provenzale J, Quinn J, Reardon DA, Rich J, Stenzel T, Tourt-Uhlig S, Wikstrand C, Wong T, Williams R, Yuan F, Zalutsky MR, Pastan I. PMID: 14649883.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCellsCTClinical Trials
    314. Forensic implications of the foot and ankle. J Foot Ankle Surg. 2003 Jul-Aug; 42(4):221-5. Rich J, Dean DE, Cheung YY. PMID: 12907933.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    315. High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas. J Clin Oncol. 2003 Jun 01; 21(11):2187-91. Gururangan S, McLaughlin C, Quinn J, Rich J, Reardon D, Halperin EC, Herndon J, Fuchs H, George T, Provenzale J, Watral M, McLendon RE, Friedman A, Friedman HS, Kurtzberg J, Vredenbergh J, Martin PL. PMID: 12775745.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    316. Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model. J Biol Chem. 2003 May 02; 278(18):15951-7. Rich JN, Shi Q, Hjelmeland M, Cummings TJ, Kuan CT, Bigner DD, Counter CM, Wang XF. PMID: 12590137.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    317. Phase II trial of temozolomide in patients with progressive low-grade glioma. J Clin Oncol. 2003 Feb 15; 21(4):646-51. Quinn JA, Reardon DA, Friedman AH, Rich JN, Sampson JH, Provenzale JM, McLendon RE, Gururangan S, Bigner DD, Herndon JE, Avgeropoulos N, Finlay J, Tourt-Uhlig S, Affronti ML, Evans B, Stafford-Fox V, Zaknoen S, Friedman HS. PMID: 12586801.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCTClinical Trials
    318. Role of C-nociceptive fibers in the nerve axon reflex-related vasodilation in diabetes. Neurology. 2003 Jan 28; 60(2):297-300. Caselli A, Rich J, Hanane T, Uccioli L, Veves A. PMID: 12552048.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCellsCTClinical Trials
    319. Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma. J Clin Oncol. 2002 May 01; 20(9):2277-83. Quinn JA, Pluda J, Dolan ME, Delaney S, Kaplan R, Rich JN, Friedman AH, Reardon DA, Sampson JH, Colvin OM, Haglund MM, Pegg AE, Moschel RC, McLendon RE, Provenzale JM, Gururangan S, Tourt-Uhlig S, Herndon JE, Bigner DD, Friedman HS. PMID: 11980998.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCTClinical Trials
    320. Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas. J Clin Oncol. 2002 Mar 01; 20(5):1389-97. Reardon DA, Akabani G, Coleman RE, Friedman AH, Friedman HS, Herndon JE, Cokgor I, McLendon RE, Pegram CN, Provenzale JM, Quinn JA, Rich JN, Regalado LV, Sampson JH, Shafman TD, Wikstrand CJ, Wong TZ, Zhao XG, Zalutsky MR, Bigner DD. PMID: 11870184.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCTClinical Trials
    321. Using living skin equivalents for diabetic foot ulceration. Int J Low Extrem Wounds. 2002 Mar; 1(1):27-32. Pham HT, Rich J, Veves A. PMID: 15871949.
      View in: PubMed   Mentions: 4     Fields:    
    322. A genetically tractable model of human glioma formation. Cancer Res. 2001 May 01; 61(9):3556-60. Rich JN, Guo C, McLendon RE, Bigner DD, Wang XF, Counter CM. PMID: 11325817.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    323. Transforming growth factor-beta signaling in cancer. Microsc Res Tech. 2001 Feb 15; 52(4):363-73. Rich J, Borton A, Wang X. PMID: 11170295.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    324. Inability of transforming growth factor-beta 1, combined with a bioabsorbable polymer paste, to promote healing of bone defects in the rat distal femur. Arch Orthop Trauma Surg. 2001; 121(4):191-6. Tielinen L, Manninen M, Puolakkainen P, Kellomäki M, Törmälä P, Rich J, Seppälä J, Rokkanen P. PMID: 11317678.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    325. Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. J Clin Oncol. 2000 Oct 15; 18(20):3522-8. Friedman HS, Pluda J, Quinn JA, Ewesuedo RB, Long L, Friedman AH, Cokgor I, Colvin OM, Haglund MM, Ashley DM, Rich JN, Sampson J, Pegg AE, Moschel RC, McLendon RE, Provenzale JM, Stewart ES, Tourt-Uhlig S, Garcia-Turner AM, Herndon JE, Bigner DD, Dolan ME. PMID: 11032594.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCTClinical Trials
    326. Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines. J Biol Chem. 1999 Dec 03; 274(49):35053-8. Rich JN, Zhang M, Datto MB, Bigner DD, Wang XF. PMID: 10574984.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    327. Irinotecan therapy in adults with recurrent or progressive malignant glioma. J Clin Oncol. 1999 May; 17(5):1516-25. Friedman HS, Petros WP, Friedman AH, Schaaf LJ, Kerby T, Lawyer J, Parry M, Houghton PJ, Lovell S, Rasheed K, Cloughsey T, Stewart ES, Colvin OM, Provenzale JM, McLendon RE, Bigner DD, Cokgor I, Haglund M, Rich J, Ashley D, Malczyn J, Elfring GL, Miller LL. PMID: 10334539.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCTClinical Trials
    328. DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma. J Clin Oncol. 1998 Dec; 16(12):3851-7. Friedman HS, McLendon RE, Kerby T, Dugan M, Bigner SH, Henry AJ, Ashley DM, Krischer J, Lovell S, Rasheed K, Marchev F, Seman AJ, Cokgor I, Rich J, Stewart E, Colvin OM, Provenzale JM, Bigner DD, Haglund MM, Friedman AH, Modrich PL. PMID: 9850030.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCells
    329. Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant glioma. J Clin Oncol. 1998 Nov; 16(11):3570-5. Friedman HS, Kokkinakis DM, Pluda J, Friedman AH, Cokgor I, Haglund MM, Ashley DM, Rich J, Dolan ME, Pegg AE, Moschel RC, McLendon RE, Kerby T, Herndon JE, Bigner DD, Schold SC. PMID: 9817277.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCTClinical Trials
    330. Invasive Aspergillus sinusitis in patients with human immunodeficiency virus infection. Report of 2 cases and review. Medicine (Baltimore). 1997 Jul; 76(4):249-55. Mylonakis E, Rich J, Skolnik PR, De Orchis DF, Flanigan T. PMID: 9279331.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    331. A prison release program for HIV-positive women: linking them to health services and community follow-up. Am J Public Health. 1996 Jun; 86(6):886-7. Flanigan TP, Kim JY, Zierler S, Rich J, Vigilante K, Bury-Maynard D. PMID: 8659671; PMCID: PMC1380412.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    332. The effect of L-amino acid oxidase on activity of melphalan against an intracranial xenograft. Cancer Chemother Pharmacol. 1995; 36(5):379-84. Rich JN, Elion GB, Wellner D, Colvin OM, Groothuis DR, Hilton JH, Schlageter KE, Bigner DD, Griffith OW, Friedman HS. PMID: 7634379.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    333. Radiochemical Solar Neutrino Experiments. Ann N Y Acad Sci. 1993 Jun; 688:364-75. Rich J, Spiro M. PMID: 26469435.
      View in: PubMed   Mentions:    Fields:    
    334. Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme. J Natl Cancer Inst. 1992 Dec 16; 84(24):1926-31. Friedman HS, Dolan ME, Moschel RC, Pegg AE, Felker GM, Rich J, Bigner DD, Schold SC. PMID: 1334154.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
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