Jenny Chong

Title(s)	SRA 3, School of Pharmacy and Pharmaceutical Science
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
vCard	Download vCard

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc Natl Acad Sci U S A. 2024 Jan 16; 121(3):e2314245121. Sarsam RD, Xu J, Lahiri I, Gong W, Li Q, Oh J, Zhou Z, Hou P, Chong J, Hao N, Li S, Wang D, Leschziner AE. PMID: 38194460; PMCID: PMC10801861.

View in: PubMed Mentions: 3 Fields:
Sci Science
Translation:Humans Animals Cells
A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase. Nat Commun. 2023 Dec 12; 14(1):8219. Oh J, Shan Z, Hoshika S, Xu J, Chong J, Benner SA, Lyumkis D, Wang D. PMID: 38086811; PMCID: PMC10716388.

View in: PubMed Mentions: Fields:
Bio Biology Sci Science
Translation:Cells
Structural basis of transcription recognition of a hydrophobic unnatural base pair by T7 RNA polymerase. Nat Commun. 2023 01 13; 14(1):195. Oh J, Kimoto M, Xu H, Chong J, Hirao I, Wang D. PMID: 36635281; PMCID: PMC9836923.

View in: PubMed Mentions: 3 Fields:
Bio Biology Sci Science
Translation:Cells
RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder. Proc Natl Acad Sci U S A. 2022 01 18; 119(3). Oh J, Jia T, Xu J, Chong J, Dervan PB, Wang D. PMID: 35022237; PMCID: PMC8784135.

View in: PubMed Mentions: 2 Fields:
Sci Science
Translation:Cells
Strand-specific effect of Rad26 and TFIIS in rescuing transcriptional arrest by CAG trinucleotide repeat slip-outs. Nucleic Acids Res. 2021 07 21; 49(13):7618-7627. Xu J, Chong J, Wang D. PMID: 34197619; PMCID: PMC8287942.

View in: PubMed Mentions: 2 Fields:
Bio Biochemistry
Translation:Cells
Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II. Nat Chem Biol. 2021 08; 17(8):906-914. Oh J, Shin J, Unarta IC, Wang W, Feldman AW, Karadeema RJ, Xu L, Xu J, Chong J, Krishnamurthy R, Huang X, Romesberg FE, Wang D. PMID: 34140682; PMCID: PMC8319059.

View in: PubMed Mentions: 7 Fields:
Bio Biology Che Chemistry
Translation:Animals Cells
Opposite roles of transcription elongation factors Spt4/5 and Elf1 in RNA polymerase II transcription through B-form versus non-B DNA structures. Nucleic Acids Res. 2021 05 21; 49(9):4944-4953. Xu J, Chong J, Wang D. PMID: 33877330; PMCID: PMC8136819.

View in: PubMed Mentions: 7 Fields:
Bio Biochemistry
Translation:Cells
Molecular basis of transcriptional pausing, stalling, and transcription-coupled repair initiation. Biochim Biophys Acta Gene Regul Mech. 2021 01; 1864(1):194659. Oh J, Xu J, Chong J, Wang D. PMID: 33271312; PMCID: PMC7836393.

View in: PubMed Mentions: 12 Fields:
Bio Biochemistry Bio Biophysics Gen Genetics Mol Molecular Biology
Translation:Humans Cells
Cockayne syndrome B protein acts as an ATP-dependent processivity factor that helps RNA polymerase II overcome nucleosome barriers. Proc Natl Acad Sci U S A. 2020 10 13; 117(41):25486-25493. Xu J, Wang W, Xu L, Chen JY, Chong J, Oh J, Leschziner AE, Fu XD, Wang D. PMID: 32989164; PMCID: PMC7568279.

View in: PubMed Mentions: 20 Fields:
Sci Science
Translation:Animals Cells
RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-π and CH-π interactions. Proc Natl Acad Sci U S A. 2020 04 28; 117(17):9338-9348. Oh J, Fleming AM, Xu J, Chong J, Burrows CJ, Wang D. PMID: 32284409; PMCID: PMC7196775.

View in: PubMed Mentions: 19 Fields:
Sci Science
Translation:Animals Cells
Molecular basis of chromatin remodeling by Rhp26, a yeast CSB ortholog. Proc Natl Acad Sci U S A. 2019 03 26; 116(13):6120-6129. Wang W, Xu J, Limbo O, Fei J, Kassavetis GA, Chong J, Kadonaga JT, Russell P, Li B, Wang D. PMID: 30867290; PMCID: PMC6442633.

View in: PubMed Mentions: 9 Fields:
Sci Science
Translation:Animals Cells
Structural and biochemical analysis of DNA lesion-induced RNA polymerase II arrest. Methods. 2019 04 15; 159-160:29-34. Oh J, Xu J, Chong J, Wang D. PMID: 30797902; PMCID: PMC6589100.

View in: PubMed Mentions: 5 Fields:
Bio Biochemistry
Translation:Animals Cells
Structural basis of DNA lesion recognition for eukaryotic transcription-coupled nucleotide excision repair. DNA Repair (Amst). 2018 11; 71:43-55. Wang W, Xu J, Chong J, Wang D. PMID: 30174298; PMCID: PMC6340766.

View in: PubMed Mentions: 23 Fields:
Bio Biochemistry Mol Molecular Biology
Translation:Humans Animals Cells
Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc Natl Acad Sci U S A. 2018 03 13; 115(11):E2538-E2545. Wang W, Walmacq C, Chong J, Kashlev M, Wang D. PMID: 29487211; PMCID: PMC5856558.

View in: PubMed Mentions: 27 Fields:
Sci Science
Translation:Cells
Structural basis for the initiation of eukaryotic transcription-coupled DNA repair. Nature. 2017 11 30; 551(7682):653-657. Xu J, Lahiri I, Wang W, Wier A, Cianfrocco MA, Chong J, Hare AA, Dervan PB, DiMaio F, Leschziner AE, Wang D. PMID: 29168508; PMCID: PMC5907806.

View in: PubMed Mentions: 104 Fields:
Sci Science
Translation:Animals Cells
Mechanism of DNA alkylation-induced transcriptional stalling, lesion bypass, and mutagenesis. Proc Natl Acad Sci U S A. 2017 08 22; 114(34):E7082-E7091. Xu L, Wang W, Wu J, Shin JH, Wang P, Unarta IC, Chong J, Wang Y, Wang D. PMID: 28784758; PMCID: PMC5576830.

View in: PubMed Mentions: 23 Fields:
Sci Science
Translation:Humans Animals Cells
RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):12426-12431. Xu L, Wang W, Gotte D, Yang F, Hare AA, Welch TR, Li BC, Shin JH, Chong J, Strathern JN, Dervan PB, Wang D. PMID: 27791148; PMCID: PMC5098678.

View in: PubMed Mentions: 18 Fields:
Sci Science
Translation:Cells
BindingDB in 2015: A public database for medicinal chemistry, computational chemistry and systems pharmacology. Nucleic Acids Res. 2016 Jan 04; 44(D1):D1045-53. Gilson MK, Liu T, Baitaluk M, Nicola G, Hwang L, Chong J. PMID: 26481362; PMCID: PMC4702793.

View in: PubMed Mentions: 447 Fields:
Bio Biochemistry
Translation:Cells
RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications. Crit Rev Biochem Mol Biol. 2015; 50(6):503-19. Xu L, Wang W, Chong J, Shin JH, Xu J, Wang D. PMID: 26392149; PMCID: PMC4891981.

View in: PubMed Mentions: 20 Fields:
Bio Biochemistry Mol Molecular Biology
Translation:Humans Animals Cells
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex. Nature. 2015 Jul 30; 523(7562):621-5. Wang L, Zhou Y, Xu L, Xiao R, Lu X, Chen L, Chong J, Li H, He C, Fu XD, Wang D. PMID: 26123024; PMCID: PMC4521995.

View in: PubMed Mentions: 75 Fields:
Sci Science
Translation:Animals Cells
Impact of template backbone heterogeneity on RNA polymerase II transcription. Nucleic Acids Res. 2015 Feb 27; 43(4):2232-41. Xu L, Wang W, Zhang L, Chong J, Huang X, Wang D. PMID: 25662224; PMCID: PMC4344504.

View in: PubMed Mentions: 10 Fields:
Bio Biochemistry
Translation:Cells
Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif. Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52):18566-71. Wang L, Limbo O, Fei J, Chen L, Kim B, Luo J, Chong J, Conaway RC, Conaway JW, Ranish JA, Kadonaga JT, Russell P, Wang D. PMID: 25512493; PMCID: PMC4284531.

View in: PubMed Mentions: 17 Fields:
Sci Science
Translation:Humans Animals Cells
Pyrene-based quantitative detection of the 5-formylcytosine loci symmetry in the CpG duplex content during TET-dependent demethylation. Angew Chem Int Ed Engl. 2014 Oct 13; 53(42):11223-7. Xu L, Chen YC, Chong J, Fin A, McCoy LS, Xu J, Zhang C, Wang D. PMID: 25159856; PMCID: PMC4227401.

View in: PubMed Mentions: 13 Fields:
Che Chemistry
Translation:Cells
Strand-specific (asymmetric) contribution of phosphodiester linkages on RNA polymerase II transcriptional efficiency and fidelity. Proc Natl Acad Sci U S A. 2014 Aug 12; 111(32):E3269-76. Xu L, Zhang L, Chong J, Xu J, Huang X, Wang D. PMID: 25074911; PMCID: PMC4136571.

View in: PubMed Mentions: 7 Fields:
Sci Science
Translation:Animals Cells
Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis. DNA Repair (Amst). 2014 Jul; 19:71-83. Xu L, Da L, Plouffe SW, Chong J, Kool E, Wang D. PMID: 24767259; PMCID: PMC4051827.

View in: PubMed Mentions: 21 Fields:
Bio Biochemistry Mol Molecular Biology
Translation:Cells
Dissecting the chemical interactions and substrate structural signatures governing RNA polymerase II trigger loop closure by synthetic nucleic acid analogues. Nucleic Acids Res. 2014 May; 42(9):5863-70. Xu L, Butler KV, Chong J, Wengel J, Kool ET, Wang D. PMID: 24692664; PMCID: PMC4027217.

View in: PubMed Mentions: 12 Fields:
Bio Biochemistry
Translation:Animals Cells
A Chemical Probe Targets DNA 5-Formylcytosine Sites and Inhibits TDG Excision, Polymerases Bypass, and Gene Expression. Chem Sci. 2014 Feb 01; 5(2):567-574. Xu L, Chen YC, Nakajima S, Chong J, Wang L, Lan L, Zhang C, Wang D. PMID: 24883182; PMCID: PMC4038700.

View in: PubMed Mentions: 6
A chemical perspective on transcriptional fidelity: dominant contributions of sugar integrity revealed by unlocked nucleic acids. Angew Chem Int Ed Engl. 2013 Nov 18; 52(47):12341-5. Xu L, Plouffe SW, Chong J, Wengel J, Wang D. PMID: 24167045; PMCID: PMC3866818.

View in: PubMed Mentions: 11 Fields:
Che Chemistry
Translation:Cells
Effect of a monofunctional phenanthriplatin-DNA adduct on RNA polymerase II transcriptional fidelity and translesion synthesis. J Am Chem Soc. 2013 Sep 04; 135(35):13054-61. Kellinger MW, Park GY, Chong J, Lippard SJ, Wang D. PMID: 23927577; PMCID: PMC3791135.

View in: PubMed Mentions: 37 Fields:
Che Chemistry
Translation:Cells
5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription. Nat Struct Mol Biol. 2012 Aug; 19(8):831-3. Kellinger MW, Song CX, Chong J, Lu XY, He C, Wang D. PMID: 22820989; PMCID: PMC3414690.

View in: PubMed Mentions: 112 Fields:
Mol Molecular Biology
Translation:Humans Cells
Dissecting chemical interactions governing RNA polymerase II transcriptional fidelity. J Am Chem Soc. 2012 May 16; 134(19):8231-40. Kellinger MW, Ulrich S, Chong J, Kool ET, Wang D. PMID: 22509745; PMCID: PMC3367139.

View in: PubMed Mentions: 24 Fields:
Che Chemistry
Translation:Animals Cells