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James Martin

TitleAssistant Clinical Professor
InstitutionUniversity of California San Diego
DepartmentPediatrics
Address9500 Gilman Drive #0984
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Leach JP, Martin J. Cardiomyocyte Proliferation for Therapeutic Regeneration. Curr Cardiol Rep. 2018 Jun 14; 20(8):63. PMID: 29904823.
      View in: PubMed
    2. Hill MC, Martin J. Heart muscle regeneration: the wonder of a Cardio-Cocktail. Cell Res. 2018 May; 28(5):503-504. PMID: 29674740.
      View in: PubMed
    3. Kadow ZA, Martin J. A Role for Ploidy in Heart Regeneration. Dev Cell. 2018 02 26; 44(4):403-404. PMID: 29486188.
      View in: PubMed
    4. Wang S, Singh M, Tran TT, Leach J, Aglyamov SR, Larina IV, Martin J, Larin KV. Biomechanical assessment of myocardial infarction using optical coherence elastography. Biomed Opt Express. 2018 Feb 01; 9(2):728-742. PMID: 29552408.
      View in: PubMed
    5. Li AH, Hanchard NA, Furthner D, Fernbach S, Azamian M, Nicosia A, Rosenfeld J, Muzny D, D'Alessandro LCA, Morris S, Jhangiani S, Parekh DR, Franklin WJ, Lewin M, Towbin JA, Penny DJ, Fraser CD, Martin J, Eng C, Lupski JR, Gibbs RA, Boerwinkle E, Belmont JW. Whole exome sequencing in 342 congenital cardiac left sided lesion cases reveals extensive genetic heterogeneity and complex inheritance patterns. Genome Med. 2017 Oct 31; 9(1):95. PMID: 29089047.
      View in: PubMed
    6. Leach JP, Heallen T, Zhang M, Rahmani M, Morikawa Y, Hill MC, Segura A, Willerson JT, Martin J. Hippo pathway deficiency reverses systolic heart failure after infarction. Nature. 2017 10 12; 550(7675):260-264. PMID: 28976966.
      View in: PubMed
    7. Eschenhagen T, Bolli R, Braun T, Field LJ, Fleischmann BK, Frisén J, Giacca M, Hare JM, Houser S, Lee RT, Marbán E, Martin J, Molkentin JD, Murry CE, Riley PR, Ruiz-Lozano P, Sadek HA, Sussman MA, Hill JA. Cardiomyocyte Regeneration: A Consensus Statement. Circulation. 2017 Aug 15; 136(7):680-686. PMID: 28684531.
      View in: PubMed
    8. Morikawa Y, Heallen T, Leach J, Xiao Y, Martin J. Dystrophin-glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation. Nature. 2017 07 13; 547(7662):227-231. PMID: 28581498.
      View in: PubMed
    9. Jarrett KE, Lee CM, Yeh YH, Hsu RH, Gupta R, Zhang M, Rodriguez PJ, Lee CS, Gillard BK, Bissig KD, Pownall HJ, Martin J, Bao G, Lagor WR. Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease. Sci Rep. 2017 Mar 16; 7:44624. PMID: 28300165.
      View in: PubMed
    10. Le NT, Martin J, Fujiwara K, Abe JI. Sub-cellular localization specific SUMOylation in the heart. Biochim Biophys Acta. 2017 Aug; 1863(8):2041-2055. PMID: 28130202.
      View in: PubMed
    11. Yi J, Lu L, Yanger K, Wang W, Sohn BH, Stanger BZ, Zhang M, Martin J, Ajani JA, Chen J, Lee JS, Song S, Johnson RL. Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ. Hepatology. 2016 11; 64(5):1757-1772. PMID: 27531557.
      View in: PubMed
    12. Xiao Y, Leach J, Wang J, Martin J. Hippo/Yap Signaling in Cardiac Development and Regeneration. Curr Treat Options Cardiovasc Med. 2016 Jun; 18(6):38. PMID: 27040401.
      View in: PubMed
    13. Chen X, Qin L, Liu Z, Liao L, Martin J, Xu J. Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype. Int J Biol Sci. 2015; 11(9):1056-72. PMID: 26221073; PMCID: PMC4515817.
    14. Tao G, Wang J, Martin J. Small RNA: from development to regeneration. Sci Transl Med. 2015 Mar 18; 7(279):279fs12. PMID: 25787761.
      View in: PubMed
    15. Chiang DY, Zhang M, Voigt N, Alsina KM, Jakob H, Martin J, Dobrev D, Wehrens XH, Li N. Identification of microRNA-mRNA dysregulations in paroxysmal atrial fibrillation. Int J Cardiol. 2015 Apr 01; 184:190-7. PMID: 25706326; PMCID: PMC4417399.
    16. Niklewski PJ, Phero JC, Martin J, Lisco SJ. A novel index of hypoxemia for assessment of risk during procedural sedation. Anesth Analg. 2014 Oct; 119(4):848-56. PMID: 25232693.
      View in: PubMed
    17. Sadek HA, Martin J, Takeuchi JK, Leor J, Nie Y, Nei Y, Giacca M, Lee RT. Multi-investigator letter on reproducibility of neonatal heart regeneration following apical resection. Stem Cell Reports. 2014 Jul 08; 3(1):1. PMID: 25068114; PMCID: PMC4110774.
    18. Yen ST, Zhang M, Deng JM, Usman SJ, Smith CN, Parker-Thornburg J, Swinton PG, Martin J, Behringer RR. Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes. Dev Biol. 2014 Sep 01; 393(1):3-9. PMID: 24984260; PMCID: PMC4166609.
    19. Song S, Ajani JA, Honjo S, Maru DM, Chen Q, Scott AW, Heallen TR, Xiao L, Hofstetter WL, Weston B, Lee JH, Wadhwa R, Sudo K, Stroehlein JR, Martin J, Hung MC, Johnson RL. Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties. Cancer Res. 2014 Aug 01; 74(15):4170-82. PMID: 24906622; PMCID: PMC4136429.
    20. Wang J, Martin J. Macro advances in microRNAs and myocardial regeneration. Curr Opin Cardiol. 2014 May; 29(3):207-13. PMID: 24625819; PMCID: PMC4286387.
    21. Chaudhury A, Kongchan N, Gengler JP, Mohanty V, Christiansen AE, Fachini JM, Martin J, Neilson JR. A piggyBac-based reporter system for scalable in vitro and in vivo analysis of 3' untranslated region-mediated gene regulation. Nucleic Acids Res. 2014 Jun; 42(10):e86. PMID: 24753411; PMCID: PMC4041432.
    22. Tao G, Martin J. MicroRNAs get to the heart of development. Elife. 2013 Nov 19; 2:e01710. PMID: 24252874; PMCID: PMC3833033.
    23. Wang J, Bai Y, Li H, Greene SB, Klysik E, Yu W, Schwartz RJ, Williams TJ, Martin J. MicroRNA-17-92, a direct Ap-2a transcriptional target, modulates T-box factor activity in orofacial clefting. PLoS Genet. 2013; 9(9):e1003785. PMID: 24068957; PMCID: PMC3777996.
    24. Stewart CA, Wang Y, Bonilla-Claudio M, Martin J, Gonzalez G, Taketo MM, Behringer RR. CTNNB1 in mesenchyme regulates epithelial cell differentiation during Müllerian duct and postnatal uterine development. Mol Endocrinol. 2013 Sep; 27(9):1442-54. PMID: 23904126; PMCID: PMC3753424.
    25. Yang W, Guo D, Harris MA, Cui Y, Gluhak-Heinrich J, Wu J, Chen XD, Skinner C, Nyman JS, Edwards JR, Mundy GR, Lichtler A, Kream BE, Rowe DW, Kalajzic I, David V, Quarles DL, Villareal D, Scott G, Ray M, Liu S, Martin J, Mishina Y, Harris SE. Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells. J Cell Sci. 2013 Sep 15; 126(Pt 18):4085-98. PMID: 23843612; PMCID: PMC3772385.
    26. Jia S, Zhou J, Gao Y, Baek JA, Martin J, Lan Y, Jiang R. Roles of Bmp4 during tooth morphogenesis and sequential tooth formation. Development. 2013 Jan 15; 140(2):423-32. PMID: 23250216; PMCID: PMC3597212.
    27. Wang J, Greene SB, Martin J. BMP signaling in congenital heart disease: new developments and future directions. Birth Defects Res A Clin Mol Teratol. 2011 Jun; 91(6):441-8. PMID: 21384533; PMCID: PMC3124406.
    28. Huang Z, Wang D, Ihida-Stansbury K, Jones PL, Martin J. Defective pulmonary vascular remodeling in Smad8 mutant mice. Hum Mol Genet. 2009 Aug 01; 18(15):2791-801. PMID: 19419974; PMCID: PMC2706683.
    29. Kurpios NA, Ibañes M, Davis NM, Lui W, Katz T, Martin J, Izpisúa Belmonte JC, Tabin CJ. The direction of gut looping is established by changes in the extracellular matrix and in cell:cell adhesion. Proc Natl Acad Sci U S A. 2008 Jun 24; 105(25):8499-506. PMID: 18574143; PMCID: PMC2438376.
    30. Cretekos CJ, Wang Y, Green ED, Martin J, Rasweiler JJ, Behringer RR. Regulatory divergence modifies limb length between mammals. Genes Dev. 2008 Jan 15; 22(2):141-51. PMID: 18198333; PMCID: PMC2192750.
    31. Pangas SA, Li X, Umans L, Zwijsen A, Huylebroeck D, Gutierrez C, Wang D, Martin J, Jamin SP, Behringer RR, Robertson EJ, Matzuk MM. Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice. Mol Cell Biol. 2008 Jan; 28(1):248-57. PMID: 17967875; PMCID: PMC2223289.
    32. Zhang Z, Cerrato F, Xu H, Vitelli F, Morishima M, Vincentz J, Furuta Y, Ma L, Martin J, Baldini A, Lindsay E. Tbx1 expression in pharyngeal epithelia is necessary for pharyngeal arch artery development. Development. 2005 Dec; 132(23):5307-15. PMID: 16284121.
      View in: PubMed
    33. Ma L, Martin J. Generation of a Bmp2 conditional null allele. Genesis. 2005 Jul; 42(3):203-6. PMID: 15986484.
      View in: PubMed
    34. Ferraro TN, Golden GT, Smith GG, Martin J, Schwebel CL, Doyle GA, Buono RJ, Berrettini WH. Confirmation of a major QTL influencing oral morphine intake in C57 and DBA mice using reciprocal congenic strains. Neuropsychopharmacology. 2005 Apr; 30(4):742-6. PMID: 15508023.
      View in: PubMed
    35. Liu W, Sun X, Braut A, Mishina Y, Behringer RR, Mina M, Martin J. Distinct functions for Bmp signaling in lip and palate fusion in mice. Development. 2005 Mar; 132(6):1453-61. PMID: 15716346.
      View in: PubMed
    36. Lee CT, Li L, Takamoto N, Martin J, Demayo FJ, Tsai MJ, Tsai SY. The nuclear orphan receptor COUP-TFII is required for limb and skeletal muscle development. Mol Cell Biol. 2004 Dec; 24(24):10835-43. PMID: 15572686; PMCID: PMC533959.
    37. Matthews KW, Drouin SM, Liu C, Martin J, Skidgel RA, Wetsel RA. Expression of the third complement component (C3) and carboxypeptidase N small subunit (CPN1) during mouse embryonic development. Dev Comp Immunol. 2004 May 17; 28(6):647-55. PMID: 15177117.
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    38. Xia C, Ma W, Stafford LJ, Liu C, Gong L, Martin J, Liu M. GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins. Mol Cell Biol. 2003 Apr; 23(7):2476-88. PMID: 12640130; PMCID: PMC150724.
    39. Akiyama H, Chaboissier MC, Martin J, Schedl A, de Crombrugghe B. The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev. 2002 Nov 01; 16(21):2813-28. PMID: 12414734; PMCID: PMC187468.