James Mangan

Title(s)Clinical Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Acute Lymphoblastic Leukemia, Version 2.2024, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2024 10; 22(8):563-576. Shah B, Mattison RJ, Abboud R, Abdelmessieh P, Aldoss I, Burke PW, DeAngelo DJ, Dinner S, Fathi AT, Gauthier J, Haddadin M, Jain N, Jonas B, Kirby S, Liedtke M, Litzow M, Logan A, Long M, Luger S, Mangan JK, Massaro S, May W, Oluwole O, Park J, Przespolewski A, Rangaraju S, Saygin C, Schwartz M, Shami P, Tomlinson B, Webster J, Awotiwon A, Stehman K. PMID: 39413812.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    2. Results from phase 1 of the MANIFEST clinical trial to evaluate the safety and tolerability of pelabresib in patients with myeloid malignancies. Leuk Lymphoma. 2024 Apr; 65(4):503-510. Stein EM, Fathi AT, Harb WA, Colak G, Fusco A, Mangan JK. PMID: 38259250.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    3. IDH2-mutated near ETP-ALL with aggressive leukemia cutis and brisk response to venetoclax and decitabine. Leuk Res Rep. 2024; 21:100408. Vaidya P, Wang HY, Don MD, Hinds BR, Mangan JK. PMID: 38269085; PMCID: PMC10805932.
      View in: PubMed   Mentions:
    4. Myeloid lineage switch following CD7-targeted chimeric antigen receptor T-cell therapy in relapsed/refractory T-cell acute lymphoblastic leukemia. Haematologica. 2023 12 01; 108(12):3511-3516. Aldoss I, Tizro P, Bedi D, Mangan JK, Clark MC, Spencer D, Song JY, Cherian S, Pillai R, Kim Y, Mahajan N, Gendzekhadze K, James M, Jacobs K, Davidson-Moncada J, Forman SJ, Wang HY, Afkhami M. PMID: 37470155; PMCID: PMC10690902.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Acute Myeloid Leukemia, Version 3.2023, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2023 05; 21(5):503-513. Pollyea DA, Altman JK, Assi R, Bixby D, Fathi AT, Foran JM, Gojo I, Hall AC, Jonas BA, Kishtagari A, Lancet J, Maness L, Mangan J, Mannis G, Marcucci G, Mims A, Moriarty K, Mustafa Ali M, Neff J, Nejati R, Olin R, Percival ME, Perl A, Przespolewski A, Rao D, Ravandi F, Shallis R, Shami PJ, Stein E, Stone RM, Sweet K, Thota S, Uy G, Vachhani P, Cassara CJ, Freedman-Cass DA, Stehman K. PMID: 37156478.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    6. Clofarabine and Busulfan Myeloablative Conditioning in Allogeneic Hematopoietic Cell Transplantation for Patients With Active Myeloid Malignancies. Transplant Cell Ther. 2023 02; 29(2):113-118. Connor MP, Loren AW, Hexner EO, Martin ME, Gill SI, Luger SM, Mangan JK, Perl AE, McCurdy SR, Pratz KW, Timlin C, Freyer CW, Carulli A, Catania C, Smith J, Hollander L, Zebrowski AM, Stadtmauer EA, Porter DL, Frey NV. PMID: 36336258.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Age-Adjusted Schedules of Venetoclax and Hypomethylating Agents to Treat Extremely Elderly Patients with Acute Myeloid Leukemia. Case Rep Hematol. 2022; 2022:2802680. Lee AM, Goodman AM, Mangan JK. PMID: 35515507; PMCID: PMC9064535.
      View in: PubMed   Mentions: 1  
    8. Letermovir vs. high-dose valacyclovir for cytomegalovirus prophylaxis following haploidentical or mismatched unrelated donor allogeneic hematopoietic cell transplantation receiving post-transplant cyclophosphamide. Leuk Lymphoma. 2022 08; 63(8):1925-1933. Freyer CW, Carulli A, Gier S, Ganetsky A, Timlin C, Schuster M, Babushok D, Frey NV, Gill SI, Hexner EO, Luger SM, Mangan JK, Martin ME, McCurdy SR, Perl AE, Porter DL, Pratz K, Smith J, Stadtmauer EA, Loren AW. PMID: 35188052.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    9. NCCN Guidelines® Insights: Myelodysplastic Syndromes, Version 3.2022. J Natl Compr Canc Netw. 2022 02; 20(2):106-117. Greenberg PL, Stone RM, Al-Kali A, Bennett JM, Borate U, Brunner AM, Chai-Ho W, Curtin P, de Castro CM, Deeg HJ, DeZern AE, Dinner S, Foucar C, Gaensler K, Garcia-Manero G, Griffiths EA, Head D, Jonas BA, Keel S, Madanat Y, Maness LJ, Mangan J, McCurdy S, McMahon C, Patel B, Reddy VV, Sallman DA, Shallis R, Shami PJ, Thota S, Varshavsky-Yanovsky AN, Westervelt P, Hollinger E, Shead DA, Hochstetler C. PMID: 35130502.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    10. FMS-Like Tyrosine Kinase 3 Inhibitors for the Treatment of Acute Myeloid Leukemia. Clin Lymphoma Myeloma Leuk. 2022 03; 22(3):e161-e184. Novatcheva ED, Anouty Y, Saunders I, Mangan JK, Goodman AM. PMID: 34649791.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    11. Leucovorin Rescue After Methotrexate Graft-Versus-Host Disease Prophylaxis Shortens the Duration of Mucositis, Time to Neutrophil Engraftment, and Hospital Length of Stay. Transplant Cell Ther. 2021 05; 27(5):431.e1-431.e8. Freyer CW, Gier S, Moyer ME, Berryman N, Carulli A, Ganetsky A, Timlin C, Babushok DV, Frey NV, Gill SI, Hexner EO, Loren AW, Mangan JK, Martin ME, McCurdy S, Perl AE, Smith J, Luger SM, Stadtmauer EA, Porter DL. PMID: 33965188.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    12. Venous thromboembolism following pegaspargase in adults receiving antithrombin supplementation. Leuk Lymphoma. 2020 09; 61(9):2200-2207. Freyer CW, Carulli A, Ganetsky A, Hughes ME, Krause TM, Timlin C, Frey NV, Gill SI, Hexner EO, Loren AW, Mangan JK, Martin ME, McCurdy SR, Perl AE, Pratz K, Porter DL, Luger SM. PMID: 32482107.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Risk of invasive fungal infections in patients with high-risk MDS and AML receiving hypomethylating agents. Am J Hematol. 2020 07; 95(7):792-798. Kim GYG, Burns J, Freyer CW, Hamilton KW, Frey NV, Gill SI, Hexner EO, Luger SM, Mangan JK, Martin ME, McCurdy SR, Perl AE, Porter DL, Schuster MG, Stadtmauer EA, Loren AW. PMID: 32242967.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    14. Optimizing Chimeric Antigen Receptor T-Cell Therapy for Adults With Acute Lymphoblastic Leukemia. J Clin Oncol. 2020 02 10; 38(5):415-422. Frey NV, Shaw PA, Hexner EO, Pequignot E, Gill S, Luger SM, Mangan JK, Loren AW, Perl AE, Maude SL, Grupp SA, Shah NN, Gilmore J, Lacey SF, Melenhorst JJ, Levine BL, June CH, Porter DL. PMID: 31815579; PMCID: PMC8312030.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansCTClinical Trials
    15. Persistent Mixed Donor Chimerism following Double Umbilical Cord Transplantation in a Patient with T-Cell Prolymphocytic Leukemia. Case Rep Hematol. 2019; 2019:8437805. Mistry RH, Hexner EO, Mangan JK. PMID: 31612087; PMCID: PMC6755299.
      View in: PubMed   Mentions: 1  
    16. Oral Vancomycin Prophylaxis Is Highly Effective in Preventing Clostridium difficile Infection in Allogeneic Hematopoietic Cell Transplant Recipients. Clin Infect Dis. 2019 05 30; 68(12):2003-2009. Ganetsky A, Han JH, Hughes ME, Babushok DV, Frey NV, Gill SI, Hexner EO, Loren AW, Luger SM, Mangan JK, Martin ME, Smith J, Freyer CW, Gilmar C, Schuster M, Stadtmauer EA, Porter DL. PMID: 30256954; PMCID: PMC6541731.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    17. Dose-related periorbital edema following sorafenib in a patient with acute myeloid leukemia. J Oncol Pharm Pract. 2019 Dec; 25(8):2035-2037. Freyer CW, Mangan JK. PMID: 30537918.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Extended CCR5 Blockade for Graft-versus-Host Disease Prophylaxis Improves Outcomes of Reduced-Intensity Unrelated Donor Hematopoietic Cell Transplantation: A Phase II Clinical Trial. Biol Blood Marrow Transplant. 2019 03; 25(3):515-521. Reshef R, Ganetsky A, Acosta EP, Blauser R, Crisalli L, McGraw J, Frey NV, Hexner EO, Hoxie JA, Loren AW, Luger SM, Mangan J, Stadtmauer EA, Mick R, Vonderheide RH, Porter DL. PMID: 30315941; PMCID: PMC6445759.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    19. Tocilizumab for the treatment of severe steroid-refractory acute graft-versus-host disease of the lower gastrointestinal tract. Bone Marrow Transplant. 2019 02; 54(2):212-217. Ganetsky A, Frey NV, Hexner EO, Loren AW, Gill SI, Luger SM, Mangan JK, Martin ME, Babushok DV, Drobyski WR, Smith J, Timlin C, Freyer CW, Stadtmauer EA, Porter DL. PMID: 29795429.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    20. Sirolimus enhances remission induction in patients with high risk acute myeloid leukemia and mTORC1 target inhibition. Invest New Drugs. 2018 08; 36(4):657-666. Kasner MT, Mick R, Jeschke GR, Carabasi M, Filicko-O'Hara J, Flomenberg N, Frey NV, Hexner EO, Luger SM, Loren AW, Mangan JK, Wagner JL, Weiss M, Carroll M, Perl AE. PMID: 29607465; PMCID: PMC6060002.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCellsCTClinical Trials
    21. Edema with hypoalbuminemia as a rare manifestation of chronic graft versus host disease after allogeneic hematopoietic cell transplant. Leuk Lymphoma. 2017 08; 58(8):2008-2010. Hogan JJ, Loren AW, Denker MG, Mangan JK. PMID: 27998198.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Differences in treatment goals and perception of symptom burden between patients with myeloproliferative neoplasms (MPNs) and hematologists/oncologists in the United States: Findings from the MPN Landmark survey. Cancer. 2017 02 01; 123(3):449-458. Mesa RA, Miller CB, Thyne M, Mangan J, Goldberger S, Fazal S, Ma X, Wilson W, Paranagama DC, Dubinski DG, Naim A, Parasuraman S, Boyle J, Mascarenhas JO. PMID: 27690182; PMCID: PMC5297986.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    23. Unrelated donors are associated with improved relapse-free survival compared to related donors in patients with myelodysplastic syndrome undergoing reduced intensity allogeneic stem cell transplantation. Am J Hematol. 2016 09; 91(9):883-7. Yam C, Crisalli L, Luger SM, Loren AW, Hexner EO, Frey NV, Mangan JK, Gao A, Stadtmauer EA, Porter DL, Reshef R. PMID: 27197602; PMCID: PMC5066393.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. An Intraoral Mass Associated With Myelodysplastic Syndrome. JAMA Oncol. 2016 May 01; 2(5):679-680. Mangan JK, Chmieliauskaite M, Stoopler ET. PMID: 27031778.
      View in: PubMed   Mentions:    Fields:    
    25. Infusion of CD3/CD28 costimulated umbilical cord blood T cells at the time of single umbilical cord blood transplantation may enhance engraftment. Am J Hematol. 2016 May; 91(5):453-60. Hexner EO, Luger SM, Reshef R, Jeschke GR, Mangan JK, Frey NV, Frank DM, Richman LP, Vonderheide RH, Aqui NA, Rosenbach M, Zhang Y, Chew A, Loren AW, Stadtmauer EA, Levine BL, June CH, Emerson SG, Porter DL. PMID: 26858124; PMCID: PMC6145177.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsCTClinical Trials
    26. Myeloproliferative neoplasms (MPNs) have a significant impact on patients' overall health and productivity: the MPN Landmark survey. BMC Cancer. 2016 Feb 27; 16:167. Mesa R, Miller CB, Thyne M, Mangan J, Goldberger S, Fazal S, Ma X, Wilson W, Paranagama DC, Dubinski DG, Boyle J, Mascarenhas JO. PMID: 26922064; PMCID: PMC4769833.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    27. High Graft CD8 Cell Dose Predicts Improved Survival and Enables Better Donor Selection in Allogeneic Stem-Cell Transplantation With Reduced-Intensity Conditioning. J Clin Oncol. 2015 Jul 20; 33(21):2392-8. Reshef R, Huffman AP, Gao A, Luskin MR, Frey NV, Gill SI, Hexner EO, Kambayashi T, Loren AW, Luger SM, Mangan JK, Nasta SD, Richman LP, Sell M, Stadtmauer EA, Vonderheide RH, Mick R, Porter DL. PMID: 26056179; PMCID: PMC4500833.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    28. Approach to patients with primary refractory acute myeloid leukemia. Curr Opin Hematol. 2015 Mar; 22(2):97-107. Orlowski RJ, Mangan JK, Luger SM. PMID: 25575037.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    29. Acute cholecystitis is a common complication after allogeneic stem cell transplantation and is associated with the use of total parenteral nutrition. Biol Blood Marrow Transplant. 2015 Apr; 21(4):768-71. Bagley SJ, Sehgal AR, Gill S, Frey NV, Hexner EO, Loren AW, Mangan JK, Porter DL, Stadtmauer EA, Reshef R, Luger SM. PMID: 25543093.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. Early donor chimerism levels predict relapse and survival after allogeneic stem cell transplantation with reduced-intensity conditioning. Biol Blood Marrow Transplant. 2014 Nov; 20(11):1758-66. Reshef R, Hexner EO, Loren AW, Frey NV, Stadtmauer EA, Luger SM, Mangan JK, Gill SI, Vassilev P, Lafferty KA, Smith J, Van Deerlin VM, Mick R, Porter DL. PMID: 25016197; PMCID: PMC4194246.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    31. Acute myeloid leukemia with translocation t(8;16) presents with features which mimic acute promyelocytic leukemia and is associated with poor prognosis. Leuk Res. 2013 Jan; 37(1):32-6. Diab A, Zickl L, Abdel-Wahab O, Jhanwar S, Gulam MA, Panageas KS, Patel JP, Jurcic J, Maslak P, Paietta E, Mangan JK, Carroll M, Fernandez HF, Teruya-Feldstein J, Luger SM, Douer D, Litzow MR, Lazarus HM, Rowe JM, Levine RL, Tallman MS. PMID: 23102703; PMCID: PMC5382928.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    32. A paraneoplastic syndrome characterized by extremity swelling with associated inflammatory infiltrate heralds aggressive transformation of myelodysplastic syndromes/myeloproliferative neoplasms to acute myeloid leukemia: a case series. Case Rep Hematol. 2012; 2012:582950. Mangan JK, Luger SM. PMID: 22928125; PMCID: PMC3420449.
      View in: PubMed   Mentions: 3  
    33. Runx1 loss minimally impacts long-term hematopoietic stem cells. PLoS One. 2011; 6(12):e28430. Cai X, Gaudet JJ, Mangan JK, Chen MJ, De Obaldia ME, Oo Z, Ernst P, Speck NA. PMID: 22145044; PMCID: PMC3228772.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    34. Salvage therapy for relapsed or refractory acute myeloid leukemia. Ther Adv Hematol. 2011 Apr; 2(2):73-82. Mangan JK, Luger SM. PMID: 23556078; PMCID: PMC3573399.
      View in: PubMed   Mentions: 13  
    35. RUNX1 mutations in clonal myeloid disorders: from conventional cytogenetics to next generation sequencing, a story 40 years in the making. Crit Rev Oncog. 2011; 16(1-2):77-91. Mangan JK, Speck NA. PMID: 22150309; PMCID: PMC3248792.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    36. Profound neutropenia resulting from metyrapone-induced adrenal crisis. Am J Hematol. 2009 Nov; 84(11):773. Mangan JK, Russell JE. PMID: 19760797.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Granulocyte colony-stimulating factor-induced upregulation of Jak3 transcription during granulocytic differentiation is mediated by the cooperative action of Sp1 and Stat3. Oncogene. 2006 Apr 20; 25(17):2489-99. Mangan JK, Tantravahi RV, Rane SG, Reddy EP. PMID: 16518416.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    38. Activation of the Jak3 pathway and myeloid differentiation. Leuk Lymphoma. 2005 Jan; 46(1):21-7. Mangan JK, Reddy EP. PMID: 15621777.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    39. Mechanisms associated with IL-6-induced up-regulation of Jak3 and its role in monocytic differentiation. Blood. 2004 Jun 01; 103(11):4093-101. Mangan JK, Rane SG, Kang AD, Amanullah A, Wong BC, Reddy EP. PMID: 14976041.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    40. Activation of the Jak3 pathway is associated with granulocytic differentiation of myeloid precursor cells. Blood. 2002 Oct 15; 100(8):2753-62. Rane SG, Mangan JK, Amanullah A, Wong BC, Vora RK, Liebermann DA, Hoffman B, Graña X, Reddy EP. PMID: 12351382.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
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