James Mangan

Title(s)Associate Clinical Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Leucovorin Rescue After Methotrexate Graft-Versus-Host Disease Prophylaxis Shortens the Duration of Mucositis, Time to Neutrophil Engraftment, and Hospital Length of Stay. Transplant Cell Ther. 2021 May; 27(5):431.e1-431.e8. Freyer CW, Gier S, Moyer ME, Berryman N, Carulli A, Ganetsky A, Timlin C, Babushok DV, Frey NV, Gill SI, Hexner EO, Loren AW, Mangan JK, Martin ME, McCurdy S, Perl AE, Smith J, Luger SM, Stadtmauer EA, Porter DL. PMID: 33965188.
      View in: PubMed   Mentions:
    2. Venous thromboembolism following pegaspargase in adults receiving antithrombin supplementation. Leuk Lymphoma. 2020 09; 61(9):2200-2207. Freyer CW, Carulli A, Ganetsky A, Hughes ME, Krause TM, Timlin C, Frey NV, Gill SI, Hexner EO, Loren AW, Mangan JK, Martin ME, McCurdy SR, Perl AE, Pratz K, Porter DL, Luger SM. PMID: 32482107.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Risk of invasive fungal infections in patients with high-risk MDS and AML receiving hypomethylating agents. Am J Hematol. 2020 07; 95(7):792-798. Kim GYG, Burns J, Freyer CW, Hamilton KW, Frey NV, Gill SI, Hexner EO, Luger SM, Mangan JK, Martin ME, McCurdy SR, Perl AE, Porter DL, Schuster MG, Stadtmauer EA, Loren AW. PMID: 32242967.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    4. Optimizing Chimeric Antigen Receptor T-Cell Therapy for Adults With Acute Lymphoblastic Leukemia. J Clin Oncol. 2020 02 10; 38(5):415-422. Frey NV, Shaw PA, Hexner EO, Pequignot E, Gill S, Luger SM, Mangan JK, Loren AW, Perl AE, Maude SL, Grupp SA, Shah NN, Gilmore J, Lacey SF, Melenhorst JJ, Levine BL, June CH, Porter DL. PMID: 31815579.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    5. Persistent Mixed Donor Chimerism following Double Umbilical Cord Transplantation in a Patient with T-Cell Prolymphocytic Leukemia. Case Rep Hematol. 2019; 2019:8437805. Mistry RH, Hexner EO, Mangan JK. PMID: 31612087.
      View in: PubMed   Mentions:
    6. Oral Vancomycin Prophylaxis Is Highly Effective in Preventing Clostridium difficile Infection in Allogeneic Hematopoietic Cell Transplant Recipients. Clin Infect Dis. 2019 05 30; 68(12):2003-2009. Ganetsky A, Han JH, Hughes ME, Babushok DV, Frey NV, Gill SI, Hexner EO, Loren AW, Luger SM, Mangan JK, Martin ME, Smith J, Freyer CW, Gilmar C, Schuster M, Stadtmauer EA, Porter DL. PMID: 30256954.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    7. Dose-related periorbital edema following sorafenib in a patient with acute myeloid leukemia. J Oncol Pharm Pract. 2019 Dec; 25(8):2035-2037. Freyer CW, Mangan JK. PMID: 30537918.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Extended CCR5 Blockade for Graft-versus-Host Disease Prophylaxis Improves Outcomes of Reduced-Intensity Unrelated Donor Hematopoietic Cell Transplantation: A Phase II Clinical Trial. Biol Blood Marrow Transplant. 2019 03; 25(3):515-521. Reshef R, Ganetsky A, Acosta EP, Blauser R, Crisalli L, McGraw J, Frey NV, Hexner EO, Hoxie JA, Loren AW, Luger SM, Mangan J, Stadtmauer EA, Mick R, Vonderheide RH, Porter DL. PMID: 30315941.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    9. Tocilizumab for the treatment of severe steroid-refractory acute graft-versus-host disease of the lower gastrointestinal tract. Bone Marrow Transplant. 2019 02; 54(2):212-217. Ganetsky A, Frey NV, Hexner EO, Loren AW, Gill SI, Luger SM, Mangan JK, Martin ME, Babushok DV, Drobyski WR, Smith J, Timlin C, Freyer CW, Stadtmauer EA, Porter DL. PMID: 29795429.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    10. Sirolimus enhances remission induction in patients with high risk acute myeloid leukemia and mTORC1 target inhibition. Invest New Drugs. 2018 08; 36(4):657-666. Kasner MT, Mick R, Jeschke GR, Carabasi M, Filicko-O'Hara J, Flomenberg N, Frey NV, Hexner EO, Luger SM, Loren AW, Mangan JK, Wagner JL, Weiss M, Carroll M, Perl AE. PMID: 29607465.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsCTClinical Trials
    11. Edema with hypoalbuminemia as a rare manifestation of chronic graft versus host disease after allogeneic hematopoietic cell transplant. Leuk Lymphoma. 2017 08; 58(8):2008-2010. Hogan JJ, Loren AW, Denker MG, Mangan JK. PMID: 27998198.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Differences in treatment goals and perception of symptom burden between patients with myeloproliferative neoplasms (MPNs) and hematologists/oncologists in the United States: Findings from the MPN Landmark survey. Cancer. 2017 02 01; 123(3):449-458. Mesa RA, Miller CB, Thyne M, Mangan J, Goldberger S, Fazal S, Ma X, Wilson W, Paranagama DC, Dubinski DG, Naim A, Parasuraman S, Boyle J, Mascarenhas JO. PMID: 27690182.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    13. Unrelated donors are associated with improved relapse-free survival compared to related donors in patients with myelodysplastic syndrome undergoing reduced intensity allogeneic stem cell transplantation. Am J Hematol. 2016 09; 91(9):883-7. Yam C, Crisalli L, Luger SM, Loren AW, Hexner EO, Frey NV, Mangan JK, Gao A, Stadtmauer EA, Porter DL, Reshef R. PMID: 27197602.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. An Intraoral Mass Associated With Myelodysplastic Syndrome. JAMA Oncol. 2016 May 01; 2(5):679-680. Mangan JK, Chmieliauskaite M, Stoopler ET. PMID: 27031778.
      View in: PubMed   Mentions:    Fields:    
    15. Infusion of CD3/CD28 costimulated umbilical cord blood T cells at the time of single umbilical cord blood transplantation may enhance engraftment. Am J Hematol. 2016 May; 91(5):453-60. Hexner EO, Luger SM, Reshef R, Jeschke GR, Mangan JK, Frey NV, Frank DM, Richman LP, Vonderheide RH, Aqui NA, Rosenbach M, Zhang Y, Chew A, Loren AW, Stadtmauer EA, Levine BL, June CH, Emerson SG, Porter DL. PMID: 26858124.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
    16. Myeloproliferative neoplasms (MPNs) have a significant impact on patients' overall health and productivity: the MPN Landmark survey. BMC Cancer. 2016 Feb 27; 16:167. Mesa R, Miller CB, Thyne M, Mangan J, Goldberger S, Fazal S, Ma X, Wilson W, Paranagama DC, Dubinski DG, Boyle J, Mascarenhas JO. PMID: 26922064.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    17. High Graft CD8 Cell Dose Predicts Improved Survival and Enables Better Donor Selection in Allogeneic Stem-Cell Transplantation With Reduced-Intensity Conditioning. J Clin Oncol. 2015 Jul 20; 33(21):2392-8. Reshef R, Huffman AP, Gao A, Luskin MR, Frey NV, Gill SI, Hexner EO, Kambayashi T, Loren AW, Luger SM, Mangan JK, Nasta SD, Richman LP, Sell M, Stadtmauer EA, Vonderheide RH, Mick R, Porter DL. PMID: 26056179.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    18. Approach to patients with primary refractory acute myeloid leukemia. Curr Opin Hematol. 2015 Mar; 22(2):97-107. Orlowski RJ, Mangan JK, Luger SM. PMID: 25575037.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Acute cholecystitis is a common complication after allogeneic stem cell transplantation and is associated with the use of total parenteral nutrition. Biol Blood Marrow Transplant. 2015 Apr; 21(4):768-71. Bagley SJ, Sehgal AR, Gill S, Frey NV, Hexner EO, Loren AW, Mangan JK, Porter DL, Stadtmauer EA, Reshef R, Luger SM. PMID: 25543093.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Early donor chimerism levels predict relapse and survival after allogeneic stem cell transplantation with reduced-intensity conditioning. Biol Blood Marrow Transplant. 2014 Nov; 20(11):1758-66. Reshef R, Hexner EO, Loren AW, Frey NV, Stadtmauer EA, Luger SM, Mangan JK, Gill SI, Vassilev P, Lafferty KA, Smith J, Van Deerlin VM, Mick R, Porter DL. PMID: 25016197.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    21. Acute myeloid leukemia with translocation t(8;16) presents with features which mimic acute promyelocytic leukemia and is associated with poor prognosis. Leuk Res. 2013 Jan; 37(1):32-6. Diab A, Zickl L, Abdel-Wahab O, Jhanwar S, Gulam MA, Panageas KS, Patel JP, Jurcic J, Maslak P, Paietta E, Mangan JK, Carroll M, Fernandez HF, Teruya-Feldstein J, Luger SM, Douer D, Litzow MR, Lazarus HM, Rowe JM, Levine RL, Tallman MS. PMID: 23102703.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    22. A paraneoplastic syndrome characterized by extremity swelling with associated inflammatory infiltrate heralds aggressive transformation of myelodysplastic syndromes/myeloproliferative neoplasms to acute myeloid leukemia: a case series. Case Rep Hematol. 2012; 2012:582950. Mangan JK, Luger SM. PMID: 22928125.
      View in: PubMed   Mentions:
    23. Runx1 loss minimally impacts long-term hematopoietic stem cells. PLoS One. 2011; 6(12):e28430. Cai X, Gaudet JJ, Mangan JK, Chen MJ, De Obaldia ME, Oo Z, Ernst P, Speck NA. PMID: 22145044.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    24. Salvage therapy for relapsed or refractory acute myeloid leukemia. Ther Adv Hematol. 2011 Apr; 2(2):73-82. Mangan JK, Luger SM. PMID: 23556078.
      View in: PubMed   Mentions:
    25. RUNX1 mutations in clonal myeloid disorders: from conventional cytogenetics to next generation sequencing, a story 40 years in the making. Crit Rev Oncog. 2011; 16(1-2):77-91. Mangan JK, Speck NA. PMID: 22150309.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    26. Profound neutropenia resulting from metyrapone-induced adrenal crisis. Am J Hematol. 2009 Nov; 84(11):773. Mangan JK, Russell JE. PMID: 19760797.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Activation of the Jak3 pathway and myeloid differentiation. Leuk Lymphoma. 2005 Jan; 46(1):21-7. Mangan JK, Reddy EP. PMID: 15621777.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    28. Mechanisms associated with IL-6-induced up-regulation of Jak3 and its role in monocytic differentiation. Blood. 2004 Jun 01; 103(11):4093-101. Mangan JK, Rane SG, Kang AD, Amanullah A, Wong BC, Reddy EP. PMID: 14976041.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    29. Activation of the Jak3 pathway is associated with granulocytic differentiation of myeloid precursor cells. Blood. 2002 Oct 15; 100(8):2753-62. Rane SG, Mangan JK, Amanullah A, Wong BC, Vora RK, Liebermann DA, Hoffman B, Graña X, Reddy EP. PMID: 12351382.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells