Jacob Heng

Title(s)Assistant Professor Of Clinical, Ophthalmology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Case Report: Bilateral optic nerve head masses and retinopathy in a patient with B-cell acute lymphoblastic leukemia receiving CAR T-cell therapy masquerading as fungal endophthalmitis. Front Immunol. 2026; 17:1854882. Heng JS, Ramos-Davila E, Maiz AM, Henderson A, Eberhart CG, Liberman P, Métais JY, Gottschalk S, Schratz KE, Symons H, Bonifant CL, Handa JT. PMID: 42367755; PMCID: PMC13294182.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Bimanual Robotic Eye Manipulation Using Adaptive Sclera Force Control: Towards Safe Retinal Vein Cannulation. IEEE Trans Med Robot Bionics. 2025 Nov; 7(4):1499-1512. Esfandiari M, Kim JW, Zhang P, Heng JS, Gehlbach P, Taylor RH, Iordachita II. PMID: 41583546; PMCID: PMC12829964.
      View in: PubMed   Mentions:
    3. A Tear-Based Approach for Rapid Identification of Bacterial Pathogens in Corneal Ulcers Using Nanopore Sequencing. Transl Vis Sci Technol. 2025 Apr 01; 14(4):19. Dibbs M, Matesva M, Theotoka D, Jayaraj C, Metiku B, Demkowicz P, Heng JS, Wang Y, Bakhoum CY, Chow J, Bakhoum MF. PMID: 40244576; PMCID: PMC12013674.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Novel In-Office Procedure for Retinal Detachment. JAMA Ophthalmol. 2025 Jan 01; 143(1):60-61. Heng JS, Paulus YM. PMID: 39666351.
      View in: PubMed   Mentions:    Fields:    
    5. A Tear-Based Approach for Rapid Identification of Bacterial Pathogens in Corneal Ulcers Using Nanopore Sequencing. medRxiv. 2024 Sep 28. Dibbs M, Matesva M, Theotoka D, Jayaraj C, Metiku B, Demkowicz P, Heng JS, Wang Y, Bakhoum CY, Chow J, Bakhoum MF. PMID: 39399005; PMCID: PMC11469460.
      View in: PubMed   Mentions:
    6. Normal and Sjogren's syndrome models of the murine lacrimal gland studied at single-cell resolution. Proc Natl Acad Sci U S A. 2023 10 17; 120(42):e2311983120. Rattner A, Heng JS, Winer BL, Goff LA, Nathans J. PMID: 37812717; PMCID: PMC10589653.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    7. NK/T-cell Lymphoma With Orbital Involvement: A Case Report and Systematic Review of the Literature. Ophthalmic Plast Reconstr Surg. 2023 Jul-Aug 01; 39(4):316-327. Dhodapkar RM, Spadaro JZ, Heng JS, Sinard JH, Lee YH, Habib LA, Pointdujour-Lim R. PMID: 36692957.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Visual acuity after cataract surgery in Macular Telangiectasia Type 2 Stage 3 to 5. Int J Retina Vitreous. 2022 Jun 11; 8(1):38. Heng JS, Arevalo JF, Handa JT. PMID: 35690847; PMCID: PMC9188048.
      View in: PubMed   Mentions:
    9. Local recurrence of uveal melanoma and concomitant brain metastases associated with an activating telomerase promoter mutation seven years after secondary enucleation. Am J Ophthalmol Case Rep. 2022 Sep; 27:101607. Heng JS, Perzia BM, Sinard JH, Pointdujour-Lim R. PMID: 35707052; PMCID: PMC9189986.
      View in: PubMed   Mentions: 1  
    10. Autoimmune retinopathy with associated anti-retinal antibodies as a potential immune-related adverse event associated with immunotherapy in patients with advanced cutaneous melanoma: case series and systematic review. BMJ Open Ophthalmol. 2022; 7(1):e000889. Heng JS, Kim JM, Jones DK, Stoessel KM, Weiss SA, Sznol M, Kluger HM, Walter SD, Silverstein NA, Pointdujour-Lim R. PMID: 35047671; PMCID: PMC8724805.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    11. CRISPR Generated SIX6 and POU4F2 Reporters Allow Identification of Brain and Optic Transcriptional Differences in Human PSC-Derived Organoids. Front Cell Dev Biol. 2021; 9:764725. Wahlin KJ, Cheng J, Jurlina SL, Jones MK, Dash NR, Ogata A, Kibria N, Ray S, Eldred KC, Kim C, Heng JS, Phillips J, Johnston RJ, Gamm DM, Berlinicke C, Zack DJ. PMID: 34869356; PMCID: PMC8635054.
      View in: PubMed   Mentions: 21  
    12. Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing. Proc Natl Acad Sci U S A. 2019 Dec 26; 116(52):26734-26744. Heng JS, Hackett SF, Stein-O'Brien GL, Winer BL, Williams J, Goff LA, Nathans J. PMID: 31843893; PMCID: PMC6936593.
      View in: PubMed   Mentions: 48     Fields:    
    13. Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution. Proc Natl Acad Sci U S A. 2019 04 30; 116(18):9103-9114. Heng JS, Rattner A, Stein-O'Brien GL, Winer BL, Jones BW, Vernon HJ, Goff LA, Nathans J. PMID: 30988181; PMCID: PMC6500147.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    14. Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells. Elife. 2018 09 06; 7. Sabbagh MF, Heng JS, Luo C, Castanon RG, Nery JR, Rattner A, Goff LA, Ecker JR, Nathans J. PMID: 30188322; PMCID: PMC6126923.
      View in: PubMed   Mentions: 159     Fields:    Translation:AnimalsCells
    15. Principles of pharmacology in the eye. Br J Pharmacol. 2017 Dec; 174(23):4205-4223. Awwad S, Mohamed Ahmed AHA, Sharma G, Heng JS, Khaw PT, Brocchini S, Lockwood A. PMID: 28865239; PMCID: PMC5715579.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimals
    16. Geographical variation in glaucoma prescribing trends in England 2008-2012: an observational ecological study. BMJ Open. 2016 05 17; 6(5):e010429. Heng JS, Wormald R, Khaw PT. PMID: 27188806; PMCID: PMC4874115.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    17. Revised Baux Score and updated Charlson comorbidity index are independently associated with mortality in burns intensive care patients. Burns. 2015 Nov; 41(7):1420-7. Heng JS, Clancy O, Atkins J, Leon-Villapalos J, Williams AJ, Keays R, Hayes M, Takata M, Jones I, Vizcaychipi MP. PMID: 26187055.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    18. Filiform Polyposis Secondary to Colonic Tuberculosis Presenting as Acute Colo-Colonic Intussusception. Case Rep Surg. 2015; 2015:578263. Heng JS, Baird A, Novelli MR, Davidson RN, Bhutiani RP. PMID: 26114005; PMCID: PMC4465708.
      View in: PubMed   Mentions: 2  
    19. Metastatic renal cell carcinoma presenting with mediastinal eggshell calcification. BMJ Case Rep. 2015 Apr 28; 2015. Heng JS, Ghuman AS, Hamdulay SS, Hirji H. PMID: 25920738; PMCID: PMC4422929.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Atrial enlargement associated with non-valvular atrial fibrillation: an unusual cause of dysphagia and weight loss. BMJ Case Rep. 2015 Mar 05; 2015. Heng JS, Elghamaz A. PMID: 25743870; PMCID: PMC4368948.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Geographical analysis of socioeconomic factors in risk of domestic burn injury in London 2007-2013. Burns. 2015 May; 41(3):437-45. Heng JS, Atkins J, Clancy O, Takata M, Dunn KW, Jones I, Vizcaychipi MP. PMID: 25554260.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    22. Severity of acute ocular involvement is independently associated with time to resolution of ocular disease in toxic epidermal necrolysis patients. Br J Ophthalmol. 2015 Feb; 99(2):251-4. Heng JS, Malik N, Joshi N, Hayes M, Jones I, Fuller LC, Vizcaychipi MP. PMID: 25138767.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. J wave patterns--morphology, prevalence and nomenclature. J Electrocardiol. 2013 Nov-Dec; 46(6):505-9. Macfarlane PW, Clark EN, Heng JS. PMID: 24075127.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
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