Ilona Gaszek

Title(s)Postdoctoral Scholar, School of Pharmacy and Pharmaceutical Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Saturation mutagenesis map of generalist versus specialist adaptations of β-lactamase to novel antibiotics. bioRxiv. 2026 Feb 28. Gaszek IK, Yildiz MS, Sari L, Ahmed A, Toprak E, Lin MM. PMID: 42124703; PMCID: PMC13160169.
      View in: PubMed   Mentions:
    2. Higher-order epistasis drives evolutionary unpredictability toward novel antibiotic resistance. bioRxiv. 2025 Jul 11. Gaszek IK, Yildiz MS, Meng D, de la Paz JA, Alvarez SM, Morcos F, Lin M, Toprak E. PMID: 40672211; PMCID: PMC12265529.
      View in: PubMed   Mentions:
    3. Structural shifts in TolC facilitate Efflux-Mediated β-lactam resistance. Commun Biol. 2024 08 26; 7(1):1051. Kantarcioglu I, Gaszek IK, Guclu TF, Yildiz MS, Atilgan AR, Toprak E, Atilgan C. PMID: 39187619; PMCID: PMC11347637.
      View in: PubMed   Mentions: 4  Translation:Cells
    4. Kinetic Barrier to Enzyme Inhibition Is Manipulated by Dynamical Local Interactions in E. coli DHFR. J Chem Inf Model. 2023 08 14; 63(15):4839-4849. Cetin E, Guclu TF, Kantarcioglu I, Gaszek IK, Toprak E, Atilgan AR, Dedeoglu B, Atilgan C. PMID: 37491825; PMCID: PMC10428214.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    5. The Antibiotic Efflux Protein TolC Is a Highly Evolvable Target under Colicin E1 or TLS Phage Selection. Mol Biol Evol. 2021 09 27; 38(10):4493-4504. Tamer YT, Gaszek I, Rodrigues M, Coskun FS, Farid M, Koh AY, Russ W, Toprak E. PMID: 34175926; PMCID: PMC8476145.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    6. TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity. Cell. 2021 06 24; 184(13):3410-3425.e17. Fan W, Mar KB, Sari L, Gaszek IK, Cheng Q, Evers BM, Shelton JM, Wight-Carter M, Siegwart DJ, Lin MM, Schoggins JW. PMID: 34062120; PMCID: PMC8276836.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    7. A trimethoprim derivative impedes antibiotic resistance evolution. Nat Commun. 2021 05 19; 12(1):2949. Manna MS, Tamer YT, Gaszek I, Poulides N, Ahmed A, Wang X, Toprak FCR, Woodard DR, Koh AY, Williams NS, Borek D, Atilgan AR, Hulleman JD, Atilgan C, Tambar U, Toprak E. PMID: 34011959; PMCID: PMC8134463.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    8. High-Order Epistasis in Catalytic Power of Dihydrofolate Reductase Gives Rise to a Rugged Fitness Landscape in the Presence of Trimethoprim Selection. Mol Biol Evol. 2019 07 01; 36(7):1533-1550. Tamer YT, Gaszek IK, Abdizadeh H, Batur TA, Reynolds KA, Atilgan AR, Atilgan C, Toprak E. PMID: 30982891; PMCID: PMC6573477.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
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